TeenagersCALYPSONCT07440134
Visual and Postural Behavior in Myopic and Non-Myopic Teenagers
A study testing Ophtalmic measurements and Visuo-postual measurements in people with Teenagers and Myopia, run by Essilor International at 1 site in France.
Trial summary
The goal of this observational study is to learn whether different types of eyeglasses prescription and different types of lenses change how close teenagers hold objects when looking at them up close. Read more about this study
- Who is it for?
- Ages 12 to 17 yearsHealthy volunteers can take part
- What is being tested?
- Ophtalmic measurements and Visuo-postual measurements
- Type of treatment
- Medical device, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteFrance
- Study dates
- 3 Apr 2026to May 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 to 17 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
- Volunteer adolescent, fluent in French, able to follow protocol and read and write
- Aged between 12 and 17 years and 6 months
- Adolescent with no history, according to the participant and/or their legal representatives, of any pathology, deficit, or disorder that could interfere with visual or cognitive functions.
- If the subject wears glasses, they must have an ophthalmic prescription dated within the last year, certifying that a consultation was carried out during the previous year
- If the subject wears Essilor® Stellest® 1.0 lenses, they must have worn them for at least two (2) consecutive months prior to inclusion in the study.
- If the subject is nearsighted: -6.5D ≤ equivalent sphere ≤ -0.5D with usual correction
- If the subject is not nearsighted: -0.5 < equivalent sphere ≤ +2.5
Who cannot join
- Age < 12 years
- Age > 17 years and 6 months
- Pregnant or breastfeeding women (Article L1121-5)
- Persons (legal representatives or subjects) deprived of their liberty by a judicial or administrative decision and persons hospitalized without consent pursuant to Articles L. 3212-1 and L. 3213-1 who are not covered by the provisions of Article L. 1121-8 and persons admitted to a health or social care facility for purposes other than research
- Participants who are currently excluded from another study
- All categories of persons who are particularly protected under French law are excluded from this research (Articles L1121-5 to L1121-9 of the Public Health Code)
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- Declared neurological deficit, in particular a history of epileptic pathology or sensorimotor coordination disorders, vestibular or cerebellar pathology (e.g., balance disorders)
- Severe declared eye disease involving loss of visual field, such as glaucoma, involving loss of acuity and severe discomfort in low-light or overly bright environments, such as retinitis pigmentosa, or declared and treated dry eye syndrome.
- Gougerot-Sjögren syndrome or declared dry eye syndrome
- Declared aphakia or pseudophakia (intraocular implant)
- Declared systemic pathology, medical treatment, or medication with an effect on vision
- People with declared muscle paralysis
- Binocular vision problems such as amblyopia, strabismus, or nystagmus
- Children of employees or employees of Essilor International, Luxottica, GrandVision, and their subsidiaries
- Individuals who have undergone previous refractive surgery, have a history of strabismus surgery, or have a history of any type of eye surgery
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Paris Bastille
Paris, 75012
David Rio, Main investigator, +33(0)155964840, riod@essilor.fr
About this study
Official title: Comportement Visuo-postural Des Adolescents Myopes et Non Myopes (CALYPSO)
The goal of this observational study is to learn whether different types of eyeglasses prescription and different types of lenses change how close teenagers hold objects when looking at them up close. The study includes adolescents who are non-myopic and adolescents who are myopic and wear either single-vision lenses or lenses slowing down myopia progression.
The main questions it aims to answer are:
Read more
Do teenagers in these three groups use different average working distances (eye-to-object distance) during everyday tasks?
Does wearing Essilor® Stellest® lenses change working distance compared with wearing single-vision lenses?
Researchers will compare the three groups to see if their working distances differ.
Participants will:
Complete an initial optometric eye examination.
Come for a second visit where they perform everyday activities while wearing a motion-capture system that measures how they move and how far they hold objects.
- Being tested
- Ophtalmic measurements, Visuo-postual measurements
- Keywords
- Myopia, Ophthalmological measurements
- Medical subject headings
- Myopia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ophtalmic measurementsDevice
Participants will undergo a standard ophthalmic examination during the initial visit. All procedures are non-invasive, non-ionising, and conducted using devices routinely employed in clinical ophthalmic practice.
Visuo-postual measurementsBehavioural
The behavioral part of the study consists of a set of tasks designed to assess eye movements and visual behavior in both controlled and ecological conditions. Participants perform everyday activities while eye movements and body motion are recorded using an eye tracker and motion capture systems.
| Study group | Role | What they receive |
|---|---|---|
| non-myopic teenagers | Experimental | Not described Receives: Device: Ophtalmic measurements; Behavioral: Visuo-postual measurements |
| myopic teenagers wearing Essilor® Stellest® lenses | Experimental | Not described Receives: Device: Ophtalmic measurements; Behavioral: Visuo-postual measurements |
| myopic teenagers wearing single vision lenses | Experimental | Worn lenses do not have a myopia-control effect Receives: Device: Ophtalmic measurements; Behavioral: Visuo-postual measurements |
What is being measured
The primary outcome is the main question the study is designed to answer.
Working distance using motion capture system
Quantitative assessment of working distance in meters during near vision tasks using a motion capture system
Measured: From enrollment to 3 months after enrollment
Secondary outcomes (3)
Gaze behavior during near vision tasks accessed with an eye-tracking system
Assessment of eye movements (spatial coordinates) during near vision tasks
Measured: From enrollment to 3 months after enrollment
Posture, eye-head coordination during near-vision tasks (with motion capture system)
Quantitative evaluation of postural behavior (spatial coordinates of body parts) while performing near vision tasks.
Measured: From enrollment to 3 months after enrollment
Correlation coefficient (R2) between optometric profile and near-vision behavior
Statistical analysis of the association between participants' optometric characteristics and their near vision behavioral patterns.
Measured: From enrollment to 3 months after enrollment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Feb 2026
- Study start3 Apr 2026
- Primary completionMay 2027 (estimated)
- Study completionMay 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for TeenagersStudies of the same condition, open and under way.
- More trials run by Essilor InternationalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Essilor International
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07440134
- Sponsor's protocol ID
- WS10477
- Other IDs
- 2025-A02517-42
- Acronym
- CALYPSO
- Status last verified
- Jan 2026
- First submitted
- 12 Feb 2026
- Last updated
- 17 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comportement Visuo-postural Des Adolescents Myopes et Non Myopes (CALYPSO)
- ClinicalTrials.gov ID
- NCT07440134
- Acronym / sponsor ID
- CALYPSO / WS10477
- Keywords
- Myopia, Ophthalmological measurements
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Essilor InternationalIndustry (pharma, biotech, devices)
- Study start
- 3 Apr 2026 (actual)
- Primary completion
- May 2027 (estimated)
- Study completion
- May 2027 (estimated)
- First posted
- 27 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to learn whether different types of eyeglasses prescription and different types of lenses change how close teenagers hold objects when looking at them up close. The study includes adolescents who are non-myopic and adolescents who are myopic and wear either single-vision lenses or lenses slowing down myopia progression.
The main questions it aims to answer are:
Do teenagers in these three groups use different average working distances (eye-to-object distance) during everyday tasks?
Does wearing Essilor® Stellest® lenses change working distance compared with wearing single-vision lenses?
Researchers will compare the three groups to see if their working distances differ.
Participants will:
Complete an initial optometric eye examination.
Come for a second visit where they perform everyday activities while wearing a motion-capture system that measures how they move and how far they hold objects.
Study design
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| non-myopic teenagers | Experimental | Device: Ophtalmic measurements, Behavioral: Visuo-postual measurements |
| myopic teenagers wearing Essilor® Stellest® lenses | Experimental | Device: Ophtalmic measurements, Behavioral: Visuo-postual measurements |
| myopic teenagers wearing single vision lenses | Experimental | Device: Ophtalmic measurements, Behavioral: Visuo-postual measurementsWorn lenses do not have a myopia-control effect |
Who may qualify
- Ages
- 12 to 17 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (7 listed)
- Volunteer adolescent, fluent in French, able to follow protocol and read and write
- Aged between 12 and 17 years and 6 months
- Adolescent with no history, according to the participant and/or their legal representatives, of any pathology, deficit, or disorder that could interfere with visual or cognitive functions.
- If the subject wears glasses, they must have an ophthalmic prescription dated within the last year, certifying that a consultation was carried out during the previous year
- If the subject wears Essilor® Stellest® 1.0 lenses, they must have worn them for at least two (2) consecutive months prior to inclusion in the study.
Key exclusion criteria (15 listed)
- Age < 12 years
- Age > 17 years and 6 months
- Pregnant or breastfeeding women (Article L1121-5)
- Persons (legal representatives or subjects) deprived of their liberty by a judicial or administrative decision and persons hospitalized without consent pursuant to Articles L. 3212-1 and L. 3213-1 who are not covered by the provisions of Article L. 1121-8 and persons admitted to a health or social care facility for purposes other than research
- Participants who are currently excluded from another study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ophtalmic measurementsParticipants will undergo a standard ophthalmic examination during the initial visit. All procedures are non-invasive, non-ionising, and conducted using devices routinely employed in clinical ophthalmic practice. | Device | myopic teenagers wearing Essilor® Stellest® lenses, myopic teenagers wearing single vision lenses, non-myopic teenagers |
| Visuo-postual measurementsThe behavioral part of the study consists of a set of tasks designed to assess eye movements and visual behavior in both controlled and ecological conditions. Participants perform everyday activities while eye movements and body motion are recorded using an eye tracker and motion capture systems. | Behavioural | myopic teenagers wearing Essilor® Stellest® lenses, myopic teenagers wearing single vision lenses, non-myopic teenagers |
Primary outcome
Working distance using motion capture system
Time frame: From enrollment to 3 months after enrollment
Quantitative assessment of working distance in meters during near vision tasks using a motion capture system
3 secondary outcomes
Gaze behavior during near vision tasks accessed with an eye-tracking system
Time frame: From enrollment to 3 months after enrollment
Posture, eye-head coordination during near-vision tasks (with motion capture system)
Time frame: From enrollment to 3 months after enrollment
Correlation coefficient (R2) between optometric profile and near-vision behavior
Time frame: From enrollment to 3 months after enrollment
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ophtalmic measurements and Visuo-postual measurements in people with Teenagers and Myopia, run by Essilor International at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 15 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact David Rio, Phd (+33(0)155964840, riod@essilor.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Working distance using motion capture system (time frame: From enrollment to 3 months after enrollment). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2026.