Septal Extension Graft in RhinoplastyNCT07446426
Unilateral Septal Extension Graft and Bilateral Septal Extension Graft in Droopy Tip and Its Effect on Tip Deviation
A study testing Unilateral septal extension graft and Bilateral septal extension graft in people with Septal Extension Graft in Rhinoplasty and Primary Rhinoplasty, run by Tanta University at 1 site in Egypt.
Trial summary
This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation. Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty, Nasal Projection
- What is being tested?
- Unilateral septal extension graft and Bilateral septal extension graft
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 siteEgypt
- Study dates
- 28 Feb 2026to 30 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients above 18years
- Aesthetic complain related to nasal tip
- presented for primary rhinoplast.
Who cannot join
- Patients under 18year old
- Patients need extensive nasal reconstructions lacking septal cartilage
- Patients with severely deficient cartilaginous septum.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Yousef Elfert, Resident contact
Egypt1 site
Tanta University
Tanta
Yousef Elfert, Resident, +20 10 69690777, Yousef192356_pg@med.tanta.edu.eg
About this study
Official title: Comparison Between Unilateral Septal Extension Graft and Bilateral Septal Extension Graft in Droopy Tip and Its Effect on Tip Deviation
This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation.
Read the detailed description
The Nasal tip from an aesthetic perspective is one of the most visible nd defining features of the nose, Even with a well- shaped dorsum; a droopy, asymmetric or poorly supported tip can distort the overall appearance of the nose; as it play a key role in projection and rotation -the primary parameters that contribute to nasal attractiveness . Functionally the nasal tip is structurally essential for maintaining airway patency, A weak or collapsed tip can result in external nasal valve collapse leading to breathing issues .
The nasal tip is supported by several mechanisms including: the length and integrity of the lower lateral cartilages, the medial crural attachment to the septal cartilage, the connection to the upper lateral and lower lateral cartilages, the nasal membranous and cartilaginous septum, the anterior nasal spine, and the lateral crural attachment to the nasal aperture , Tip plasty is crucial as it ensures that the nose not only appears proportionate and aesthetically pleasing, but also functions properly, and maintains long-term structural support. Neglecting the nasal tip can result in an unnatural or imbalanced outcome even when the rest of the nose is well-shaped .
In primary rhinoplasty, the nasal tip is often the centeral cus for achieving a refined yet natural look. Tip plasty often includes several mechanisms such as (e.g., Colum umellar strut graft, septal extensions graft these are used to support or reposition the tip without compromising function. The Septal Extension Graft is considered one of the most reliable technique offering a wide range of applications. However, it may be associated with some drawbacks such as the tip's stiffness and potential aesthetical or functional issues. This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation.
- Being tested
- Unilateral septal extension graft, Bilateral septal extension graft
- Keywords
- nasal projection, Septal Extension Graft, Tip Deviation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Unilateral septal extension graftProcedure or surgery
Seventeen patients will undergo unilateral septal extension graft
Bilateral septal extension graftProcedure or surgery
Seventeen will undergo bilateral septal extension graft
| Study group | Role | What they receive |
|---|---|---|
| unilateral septal extension graft | Experimental | seventeen patients will undergo unilateral septal extension graft Receives: Procedure: Unilateral septal extension graft |
| Bilateral septal extension graft | Experimental | Seventeen will undergo bilateral septal extension graft Receives: Procedure: Bilateral septal extension graft |
What is being measured
The primary outcome is the main question the study is designed to answer.
Arabic Rhinoplasty Outcome Evaluation Questionnaire
Patient satisfaction with primary septorhinoplasty will be assessed using the Arabic Rhinoplasty Outcome Evaluation Questionnaire. Validated Arabic Rhinoplasty Outcomes Evaluation questionnaire is a 6-item, self-report tool (0-24 scale) assessing physical, emotional, and social satisfaction after nasal surgery, with higher scores (0-100%) indicating better outcomes.
Measured: 3 months
Secondary outcomes (1)
Deviation angle
Measured: 3 months after the operation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Mar 2026
- Study start28 Feb 2026 (estimated)
- Primary completion30 Oct 2026 (estimated)
- Study completion30 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Septal Extension Graft in RhinoplastyStudies of the same condition, open and under way.
- More trials run by Tanta UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 34 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tanta University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yousef Abd El Raouf Abd El Monem Elfert, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07446426
- Sponsor's protocol ID
- 36264MS1042/8/25
- Status last verified
- Oct 2025
- First submitted
- 25 Feb 2026
- Last updated
- 5 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: It will be available if it needed
Study at a glance
From the registry record, last updated by the sponsor on 5 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison Between Unilateral Septal Extension Graft and Bilateral Septal Extension Graft in Droopy Tip and Its Effect on Tip Deviation
- ClinicalTrials.gov ID
- NCT07446426
- Acronym / sponsor ID
- 36264MS1042/8/25
- Keywords
- nasal projection, Septal Extension Graft, Tip Deviation
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 34 participants (estimated)
- Lead sponsor
- Tanta UniversityUniversity, hospital or other
- Study start
- 28 Feb 2026 (estimated)
- Primary completion
- 30 Oct 2026 (estimated)
- Study completion
- 30 Oct 2026 (estimated)
- First posted
- 3 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation.
Detailed description
The Nasal tip from an aesthetic perspective is one of the most visible nd defining features of the nose, Even with a well- shaped dorsum; a droopy, asymmetric or poorly supported tip can distort the overall appearance of the nose; as it play a key role in projection and rotation -the primary parameters that contribute to nasal attractiveness . Functionally the nasal tip is structurally essential for maintaining airway patency, A weak or collapsed tip can result in external nasal valve collapse leading to breathing issues .
The nasal tip is supported by several mechanisms including: the length and integrity of the lower lateral cartilages, the medial crural attachment to the septal cartilage, the connection to the upper lateral and lower lateral cartilages, the nasal membranous and cartilaginous septum, the anterior nasal spine, and the lateral crural attachment to the nasal aperture , Tip plasty is crucial as it ensures that the nose not only appears proportionate and aesthetically pleasing, but also functions properly, and maintains long-term structural support. Neglecting the nasal tip can result in an unnatural or imbalanced outcome even when the rest of the nose is well-shaped .
In primary rhinoplasty, the nasal tip is often the centeral cus for achieving a refined yet natural look. Tip plasty often includes several mechanisms such as (e.g., Colum umellar strut graft, septal extensions graft these are used to support or reposition the tip without compromising function. The Septal Extension Graft is considered one of the most reliable technique offering a wide range of applications. However, it may be associated with some drawbacks such as the tip's stiffness and potential aesthetical or functional issues. This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| unilateral septal extension graft | Experimental | Procedure: Unilateral septal extension graftseventeen patients will undergo unilateral septal extension graft |
| Bilateral septal extension graft | Experimental | Procedure: Bilateral septal extension graftSeventeen will undergo bilateral septal extension graft |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Patients above 18years
- Aesthetic complain related to nasal tip
- presented for primary rhinoplast.
Key exclusion criteria (3 listed)
- Patients under 18year old
- Patients need extensive nasal reconstructions lacking septal cartilage
- Patients with severely deficient cartilaginous septum.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Unilateral septal extension graftSeventeen patients will undergo unilateral septal extension graft | Procedure or surgery | unilateral septal extension graft |
| Bilateral septal extension graftSeventeen will undergo bilateral septal extension graft | Procedure or surgery | Bilateral septal extension graft |
Primary outcome
Arabic Rhinoplasty Outcome Evaluation Questionnaire
Time frame: 3 months
Patient satisfaction with primary septorhinoplasty will be assessed using the Arabic Rhinoplasty Outcome Evaluation Questionnaire. Validated Arabic Rhinoplasty Outcomes Evaluation questionnaire is a 6-item, self-report tool (0-24 scale) assessing physical, emotional, and social satisfaction after nasal surgery, with higher scores (0-100%) indicating better outcomes.
1 secondary outcome
Deviation angle
Time frame: 3 months after the operation
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Mar 2026.
- Individual participant dataSharing planned: Yes. It will be available if it needed
Related trials for Septal Extension Graft in Rhinoplasty
Not yet recruiting
Outcomes Assessment of Septal Extension Graft Versus Columellar Strut Graft in Rhinoplasty.
Septal Extension Graft in Rhinoplasty
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Yousef Elfert, Resident contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Unilateral septal extension graft and Bilateral septal extension graft in people with Septal Extension Graft in Rhinoplasty and Primary Rhinoplasty, run by Tanta University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 5 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Yousef Elfert, Resident (+20 10 69690777, Yousef192356_pg@med.tanta.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Arabic Rhinoplasty Outcome Evaluation Questionnaire (time frame: 3 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2026.