AsthmaBPAT-TurkishNCT07450885
"Turkish Validation and Reliability Study of the Brompton Breathing Pattern Assessment Tool in Asthma Patients"
An observational study of Asthma and Breathing Pattern Disorder, run by Istanbul Saglik Bilimleri University at 1 site in Turkey (Türkiye).
Trial summary
The purpose of this study is to evaluate the validity and reliability of the Turkish version of the Brompton Breathing Pattern Assessment Tool (BPAT) in individuals with asthma. This study aims to determine whether the BPAT is a valid and reliable tool for assessing breathing patterns in Turkish-speaking asthma… Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Asthma, Breathing Pattern Disorder
- What is being tested?
- Brompton Breathing Pattern Assessment Tool (BPAT) - Turkish Version
- How many people
- 101 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 14 Jul 2025to 30 Apr 2026
- How long will I take part?
- 1 Week
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The participants for this study will be recruited from Health Sciences University, İstanbul Süreyyapaşa Chest Diseases and Chest Surgery Education and Research Hospital in Istanbul, Turkey. Participants will be selected based on the eligibility criteria outlined, including those diagnosed with severe persistent asthma as per the Global Initiative for Asthma (GINA) guidelines. Participants will be recruited from local clinics specializing in respiratory diseases and asthma management.
Who may be able to join
- Aged between 18 and 75 years
- Diagnosed with severe persistent asthma according to the Global Initiative for Asthma (GINA) criteria
- Turkish ethnicity
- Ability to read and write in Turkish
- Willingness to participate in the study
Who cannot join
- Having had a respiratory infection in the last 1 month
- Use of oral corticosteroids in the last 4 weeks
- Presence of malignancy, vasculitis, or pregnancy
- Body Mass Index (BMI) > 35 kg/m2
- Diagnosis of COPD or other primary respiratory diseases (excluding asthma)
- Any musculoskeletal, neurological, or cardiovascular condition that could interfere with breathing pattern assessment or impede potential respiratory physiotherapy applications
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Süreyyapaşa Chest Diseases And Thoracic Surgery Training And Research Hospital
Istanbul, Istanbul, 34844
About this study
Official title: Validity and Reliability Study of the Turkish Version of the Brompton Breathing Pattern Assessment Tool (BPAT) in Individuals With Asthma
The purpose of this study is to evaluate the validity and reliability of the Turkish version of the Brompton Breathing Pattern Assessment Tool (BPAT) in individuals with asthma. This study aims to determine whether the BPAT is a valid and reliable tool for assessing breathing patterns in Turkish-speaking asthma patients. The research question being addressed is: "Is the Turkish version of the BPAT a valid and reliable tool for assessing breathing patterns in individuals with asthma?"
Read the detailed description
This study is designed to assess the validity and reliability of the Turkish version of the Brompton Breathing Pattern Assessment Tool (BPAT). BPAT is a well-established tool used to assess the breathing patterns of individuals with respiratory conditions. In this study, a group of asthma patients will be evaluated using the BPAT to determine its applicability and consistency in the Turkish-speaking population.
The reliability of the tool will be tested through repeated measurements, and its validity will be assessed by comparing BPAT results with other validated asthma assessment tools. The data will be analyzed to evaluate the internal consistency, test-retest reliability, and construct validity of the BPAT in a clinical asthma population.
The linguistic validation process will be conducted following the ISPOR Task Force guidelines, including forward translation, reconciliation, back-translation, and cognitive debriefing. The psychometric properties of the tool, including internal consistency, test-retest reliability, and construct validity, will be evaluated according to the COSMIN checklist standards.
Additionally, participant eligibility will be defined as individuals who are diagnosed with asthma and can understand and respond to questions in Turkish. The study will also explore any cultural adaptations necessary for the Turkish version of the BPAT to ensure its cultural relevance and accuracy in assessments.
- Conditions
- Asthma, Breathing Pattern Disorder
- Being tested
- Brompton Breathing Pattern Assessment Tool (BPAT) - Turkish Version, Validation Battery (Nijmegen Questionnaire, Dyspnea-12, Asthma Control Test (ACT), Asthma Quality of Life Questionnaire (Mini AQLQ), Spirometry)
- Keywords
- Brompton Breathing Pattern Assessment Tool, Turkish Version, Validity Study, Reliability Study
- Medical subject headings
- Asthma
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Brompton Breathing Pattern Assessment Tool (BPAT) - Turkish VersionOther
A tool used to assess breathing patterns in asthma patients through clinical observation.
Validation Battery (Nijmegen Questionnaire, Dyspnea-12, Asthma Control Test (ACT), Asthma Quality of Life Questionnaire (Mini AQLQ), Spirometry)Other
A set of validated questionnaires and objective tests used to compare with BPAT results for construct validity
| Study group | Role | What they receive |
|---|---|---|
| Asthma Patients | Individuals aged 18-75, diagnosed with severe persistent asthma according to GINA criteria, who are native Turkish speakers. Receives: Other: Brompton Breathing Pattern Assessment Tool (BPAT) - Turkish Version; Other: Validation Battery (Nijmegen Questionnaire, Dyspnea-12, Asthma Control Test (ACT), Asthma Quality of Life Questionnaire (Mini AQLQ), Spirometry) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Construct Validity of the Turkish Version of the Brompton Breathing Pattern Assessment Tool (BPAT)
The study aims to evaluate the construct validity of the Turkish version of the BPAT in assessing breathing patterns among Turkish-speaking asthma patients. Validity will be determined by calculating correlation coefficients (e.g., Spearman's or Pearson's r) between the total BPAT scores, objective physiological measures (spirometry results such as FEV1 and FVC), and the scores of established reference clinical tools (Nijmegen Questionnaire, Dyspnea-12, Asthma Control Test (ACT), and Asthma Quality of Life Questionnaire (Mini-AQLQ).
Measured: Baseline
Secondary outcomes (3)
Test-Retest Reliability of the Turkish Version of BPAT
This outcome will assess the test-retest reliability of the Turkish version of BPAT by measuring the consistency of the tool in repeated assessments. The BPAT will be administered twice to the same participants. Reliability will be evaluated by calculating the Intraclass Correlation Coefficient (ICC).
Measured: 7 to 14 days
Inter-Rater Reliability of the Turkish Version of BPAT
This outcome will assess the inter-rater reliability of the Turkish version of BPAT. Two independent physiotherapists will evaluate the breathing pattern of the same asthma patient. The raters will be blinded to each other's scores to determine the consistency of the tool's application between different users. Reliability will be evaluated by calculating the Intraclass Correlation Coefficient (ICC) or Cohen's Kappa.
Measured: Baseline
Comparison of BPAT Results with Other Asthma Assessment Tools
Description: This outcome will compare the BPAT results with other validated asthma assessment tools, such as Nijmegen Questionnaire, Dyspnea-12 Questionnaire , spirometry, ACT (Asthma Control Test), and Mini AQLQ (Asthma Quality of Life Questionnaire), to determine the congruence between different assessment methods.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Mar 2026
- Study start14 Jul 2025
- Primary completion30 Apr 2026
- Study completion30 Apr 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for AsthmaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 101 participants (actual)
- Target duration
- 1 Week
Sponsor and investigators
- Lead sponsor
- Istanbul Saglik Bilimleri University
- Sponsor type
- University, hospital or other
- Collaborators
- Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital
- Responsible party
- Principal investigator, Dilek Unsal, Istanbul Saglik Bilimleri University
- Investigators
- Zuhal Kunduracılar, Prof., Principal investigator, Istanbul Gelisim UniversityFatma M. Tepetam, Prof., Study chair, Saglik Bilimleri UniversitesiŞeyma Ozden, Dr., Study chair, Saglik Bilimleri UniversitesiDilek Unsal, PT PhD(c), Principal investigator, Saglik Bilimleri UniversitesiNisanur Tutus, PT Phd (c), Study chair, Saglik Bilimleri Universitesi
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07450885
- Sponsor's protocol ID
- 25/428
- Acronym
- BPAT-Turkish
- Status last verified
- May 2026
- First submitted
- 28 Sep 2025
- Last updated
- 7 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be publicly shared in order to protect patient confidentiality and comply with the local ethics committee regulations. However, completely anonymized data may be made available upon reasonable academic request to the Principal Investigator following the publication of the study results.
Publications
Todd S, Walsted ES, Grillo L, Livingston R, Menzies-Gow A, Hull JH. Novel assessment tool to detect breathing pattern disorder in patients with refractory asthma. Respirology. 2018 Mar;23(3):284-290. doi: 10.1111/resp.13173. Epub 2017 Sep 14.
PubMed 28905471
Study at a glance
From the registry record, last updated by the sponsor on 7 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Validity and Reliability Study of the Turkish Version of the Brompton Breathing Pattern Assessment Tool (BPAT) in Individuals With Asthma
- ClinicalTrials.gov ID
- NCT07450885
- Acronym / sponsor ID
- BPAT-Turkish / 25/428
- Conditions
- Asthma, Breathing Pattern Disorder
- Keywords
- Brompton Breathing Pattern Assessment Tool, Turkish Version, Validity Study, Reliability Study
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 101 participants (actual)
- Lead sponsor
- Istanbul Saglik Bilimleri UniversityUniversity, hospital or other
- Collaborators
- Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital
- Study start
- 14 Jul 2025 (actual)
- Primary completion
- 30 Apr 2026 (actual)
- Study completion
- 30 Apr 2026 (actual)
- First posted
- 5 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to evaluate the validity and reliability of the Turkish version of the Brompton Breathing Pattern Assessment Tool (BPAT) in individuals with asthma. This study aims to determine whether the BPAT is a valid and reliable tool for assessing breathing patterns in Turkish-speaking asthma patients. The research question being addressed is: "Is the Turkish version of the BPAT a valid and reliable tool for assessing breathing patterns in individuals with asthma?"
Detailed description
This study is designed to assess the validity and reliability of the Turkish version of the Brompton Breathing Pattern Assessment Tool (BPAT). BPAT is a well-established tool used to assess the breathing patterns of individuals with respiratory conditions. In this study, a group of asthma patients will be evaluated using the BPAT to determine its applicability and consistency in the Turkish-speaking population.
The reliability of the tool will be tested through repeated measurements, and its validity will be assessed by comparing BPAT results with other validated asthma assessment tools. The data will be analyzed to evaluate the internal consistency, test-retest reliability, and construct validity of the BPAT in a clinical asthma population.
The linguistic validation process will be conducted following the ISPOR Task Force guidelines, including forward translation, reconciliation, back-translation, and cognitive debriefing. The psychometric properties of the tool, including internal consistency, test-retest reliability, and construct validity, will be evaluated according to the COSMIN checklist standards.
Additionally, participant eligibility will be defined as individuals who are diagnosed with asthma and can understand and respond to questions in Turkish. The study will also explore any cultural adaptations necessary for the Turkish version of the BPAT to ensure its cultural relevance and accuracy in assessments.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Week
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Asthma Patients | – | Other: Brompton Breathing Pattern Assessment Tool (BPAT) - Turkish Version, Other: Validation Battery (Nijmegen Questionnaire, Dyspnea-12, Asthma Control Test (ACT), Asthma Quality of Life Questionnaire (Mini AQLQ), Spirometry)Individuals aged 18-75, diagnosed with severe persistent asthma according to GINA criteria, who are native Turkish speakers. |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The participants for this study will be recruited from Health Sciences University, İstanbul Süreyyapaşa Chest Diseases and Chest Surgery Education and Research Hospital in Istanbul, Turkey. Participants will be selected based on the eligibility criteria outlined, including those diagnosed with severe persistent asthma as per the Global Initiative for Asthma (GINA) guidelines. Participants will be recruited from local clinics specializing in respiratory diseases and asthma management.
Key inclusion criteria (5 listed)
- Aged between 18 and 75 years
- Diagnosed with severe persistent asthma according to the Global Initiative for Asthma (GINA) criteria
- Turkish ethnicity
- Ability to read and write in Turkish
- Willingness to participate in the study
Key exclusion criteria (6 listed)
- Having had a respiratory infection in the last 1 month
- Use of oral corticosteroids in the last 4 weeks
- Presence of malignancy, vasculitis, or pregnancy
- Body Mass Index (BMI) > 35 kg/m2
- Diagnosis of COPD or other primary respiratory diseases (excluding asthma)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Brompton Breathing Pattern Assessment Tool (BPAT) - Turkish VersionA tool used to assess breathing patterns in asthma patients through clinical observation. | Other | Asthma Patients |
| Validation Battery (Nijmegen Questionnaire, Dyspnea-12, Asthma Control Test (ACT), Asthma Quality of Life Questionnaire (Mini AQLQ), Spirometry)A set of validated questionnaires and objective tests used to compare with BPAT results for construct validity | Other | Asthma Patients |
Primary outcome
Construct Validity of the Turkish Version of the Brompton Breathing Pattern Assessment Tool (BPAT)
Time frame: Baseline
The study aims to evaluate the construct validity of the Turkish version of the BPAT in assessing breathing patterns among Turkish-speaking asthma patients. Validity will be determined by calculating correlation coefficients (e.g., Spearman's or Pearson's r) between the total BPAT scores, objective physiological measures (spirometry results such as FEV1 and FVC), and the scores of established reference clinical tools (Nijmegen Questionnaire, Dyspnea-12, Asthma Control Test (ACT), and Asthma Quality of Life Questionnaire (Mini-AQLQ).
3 secondary outcomes
Test-Retest Reliability of the Turkish Version of BPAT
Time frame: 7 to 14 days
Inter-Rater Reliability of the Turkish Version of BPAT
Time frame: Baseline
Comparison of BPAT Results with Other Asthma Assessment Tools
Time frame: Baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 May 2026.
- Background: PubMed 28905471Todd S, Walsted ES, Grillo L, Livingston R, Menzies-Gow A, Hull JH. Novel assessment tool to detect breathing pattern disorder in patients with refractory asthma. Respirology. 2018 Mar;23(3):284-290. doi: 10.1111/resp.13173. Epub 2017 Sep 14.
- Individual participant dataSharing planned: No. Individual participant data will not be publicly shared in order to protect patient confidentiality and comply with the local ethics committee regulations. However, completely anonymized data may be made available upon reasonable academic request to the Principal Investigator following the publication of the study results.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Zuhal Kunduracılar, Prof. principal investigator
Istanbul Gelisim University
Fatma M. Tepetam, Prof. study chair
Saglik Bilimleri Universitesi
Şeyma Ozden, Dr. study chair
Saglik Bilimleri Universitesi
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Asthma and Breathing Pattern Disorder, run by Istanbul Saglik Bilimleri University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Construct Validity of the Turkish Version of the Brompton Breathing Pattern Assessment Tool (BPAT) (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07450885, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 May 2026.