Alcohol Use Disorder (AUD)NCT07451574
Acceptability and Feasibility Study of Non-alcoholic Beverages
A study testing Non-alcoholic beer and Sparkling water in people with Alcohol Use Disorder (AUD), run by Stanford University at 1 site in United States.
Trial summary
This project will elucidate the acceptability and feasibility of incorporating provision of non-alcoholic beers into alcohol use disorder treatment, for patients interested in using non-alcoholic beers as part of their recovery from alcohol use disorder. Read more about this study
- Who is it for?
- Ages 21 to 89 years
- Conditions the study is for
- Alcohol Use Disorder (AUD)
- What is being tested?
- Non-alcoholic beer and Sparkling water
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteUnited States
- Study dates
- 14 May 2026to Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 89 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Participants will be eligible if they report on the screening survey:
- living in California and provide a California mailing address (to ship study materials to)
- consuming ≤42 alcoholic beverages per week (as we seek to provide an equal count of the substitute beverage and budgetary restrictions prevent an amount greater than that)
- having alcohol use disorder documented with ≥2 symptoms on the Alcohol Symptom Checklist
- being enrolled in Ria Health treatment
- having English language fluency
Who cannot join
- Individuals will be excluded at the online screener survey stage if they do not meet all of the inclusion criteria.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Stanford Prevention Research Center
Stanford, California, 94304
About this study
Official title: Non-alcoholic Beverages as a Therapeutic Adjunct in Alcohol Use Disorder Treatment: a Pilot Study of Acceptability and Feasibility
This project will elucidate the acceptability and feasibility of incorporating provision of non-alcoholic beers into alcohol use disorder treatment, for patients interested in using non-alcoholic beers as part of their recovery from alcohol use disorder.
- Conditions
- Alcohol Use Disorder (AUD)
- Being tested
- Non-alcoholic beer, Sparkling water
- Keywords
- non-alcoholic beer, alcohol
- Medical subject headings
- Alcoholism
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Non-alcoholic beerOther
Participants will receive non-alcoholic beers and will be encouraged to consume the beverages to the extent they find useful/desirable during the 6-week study period.
Sparkling waterOther
Participants will receive sparkling water and will be encouraged to consume the beverages to the extent they find useful/desirable during the 6-week study period.
| Study group | Role | What they receive |
|---|---|---|
| Non-alcoholic beer | Experimental | Participants will receive non-alcoholic beers (volume matching alcohol volume intake prior to alcohol use disorder treatment enrollment) for 6 weeks. Receives: Other: Non-alcoholic beer |
| Sparkling water | Other | Participants will receive sparkling water (volume matching alcohol volume intake prior to alcohol use disorder treatment enrollment) for 6 weeks. Receives: Other: Sparkling water |
What is being measured
The primary outcome is the main question the study is designed to answer.
Participant Beverage Satisfaction (Acceptability)
"How satisfied were you with the beverages you received in this study?" with 5-pt scale response options ranging from "Very Unsatisfied" to "Very Satisfied." Higher scores [split by condition] will indicate greater acceptability.
Measured: Assessed at the end of week 6
Participant Intention to Consume Assigned Beverage in the Future (Acceptability)
"Do you intend to consume the beverage type you received in the future?" with 5-pt scale response options ranging from "Definitely not" to "Definitely." Higher scores [split by condition] will indicate greater acceptability.
Measured: Assessed at the end of week 6
Participant Likelihood of Recommending Beverage (Acceptability)
"Would you recommend the use of the beverage type you received for people who have alcohol use disorder?" with 5-pt scale response options ranging from "Definitely not" to "Definitely." Higher scores [split by condition] will indicate greater acceptability.
Measured: Assessed at the end of week 6
Screened Out of Contacted (Feasibility)
Percentage of participants who completed the screening measure out of those who were contacted. Higher percentage will indicate greater feasibility.
Measured: Beginning of recruitment to end of recruitment (approximately 3-6 months)
Eligible Out of Screened (Feasibility)
Percentage of participants who screen eligible out of those who were screened. Higher percentage will indicate greater feasibility.
Measured: Beginning of recruitment to end of recruitment (approximately 3-6 months)
Enrolled Out of Eligible (Feasibility)
Percentage of participants who enrolled out of those who screened eligible. Higher percentage will indicate greater feasibility.
Measured: Beginning of recruitment to end of recruitment (approximately 3-6 months)
Retention (Feasibility)
Percentage of participants who completed the study out of those who enrolled. Higher percentage [split by condition] will indicate greater feasibility.
Measured: Beginning of recruitment to end of data collection (approximately 3-6 months)
Perception of Beverage Supply (Feasibility)
Percentage of participants whose response to "How was the supply of beverages you received throughout the study?" is "just right" [as opposed to "too little" or "too much"]. Higher percentage [split by condition] will indicate greater feasibility.
Measured: Assessed at the end of week 6
Secondary outcomes (8)
Average Blood Alcohol Content Across 6 Weeks
Average blood alcohol content (measured via breathalyzer) across the 6-week period split by condition.
Measured: Study weeks 1-6
Change in Blood Alcohol Content Across 6 Weeks
Slopes of blood alcohol content separated by condition for: a) start of treatment to pre-study and b) during the 6-week study period [split by condition].
Measured: Treatment entry to week 6
Average Number of Days with Breathalyzer Readings
Average number of days with breathalyzer readings across the 6-week study.
Measured: Assessed at 6 weeks.
Median Number of Breathalyzer Readings Among Days with Readings
Median number of breathalyzer readings among days with readings across the 6-week study.
Measured: Assessed at 6 weeks.
Change in Reported Alcohol Use
Percentage of participants endorsing use of study-provided beverages who experienced (a) increase in alcohol use (defined as change in average use per week pre-study to average use per week across the study), (b) no change in alcohol use, (c) decrease in alcohol use [split by condition].
Measured: Baseline to 6 weeks.
Perceived Change in Craving
Percentage of participants endorsing use of study-provided beverages who reported (a) increased in desire to drink alcohol, (b) no change in desire to drink alcohol, (c) decreased desire to drink alcohol [split by condition] in response to the item "When I drink the study provided beverages I experience…Less desire to drink alcohol; No change in my desire to drink alcohol; or More desire to drink alcohol.
Measured: Assessed at 6 weeks.
Perceived Change in Alcohol Use
Percentage of participants endorsing use of study-provided beverages who reported (a) increased in alcohol use, (b) no change in alcohol use, (c) increased alcohol use [split by condition] in response to the item "Because I drink the study provided beverages I drink...Less alcohol than I otherwise would; The same amount of alcohol that I otherwise would; or More alcohol than I otherwise would."
Measured: Assessed at 6 weeks.
Perceived Impact of Beverages on Recovery
Percentage of participants who responded to the item "What impact did the study provided beverages have on your recovery from alcohol use disorder?" with (a) Harmful; (b) No impact; or (c) Helpful [split by condition].
Measured: Assessed at 6 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Mar 2026
- Study start14 May 2026
- Primary completionOct 2026 (estimated)
- Study completionNov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Alcohol Use Disorder (AUD)Studies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Responsible party
- Principal investigator, Molly Anne Bowdring, Stanford University
- Investigators
- Molly A Bowdring, PhD, Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07451574
- Sponsor's protocol ID
- 83997
- Other IDs
- 1K99AA031716
- Status last verified
- Jul 2026
- First submitted
- 27 Feb 2026
- Last updated
- 20 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Data will be uploaded to the NIAAA data archive
Study at a glance
From the registry record, last updated by the sponsor on 20 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Non-alcoholic Beverages as a Therapeutic Adjunct in Alcohol Use Disorder Treatment: a Pilot Study of Acceptability and Feasibility
- ClinicalTrials.gov ID
- NCT07451574
- Acronym / sponsor ID
- 83997
- Conditions
- Alcohol Use Disorder (AUD)
- Keywords
- non-alcoholic beer, alcohol
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Collaborators
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Study start
- 14 May 2026 (actual)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Nov 2026 (estimated)
- First posted
- 5 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This project will elucidate the acceptability and feasibility of incorporating provision of non-alcoholic beers into alcohol use disorder treatment, for patients interested in using non-alcoholic beers as part of their recovery from alcohol use disorder.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Non-alcoholic beer | Experimental | Other: Non-alcoholic beerParticipants will receive non-alcoholic beers (volume matching alcohol volume intake prior to alcohol use disorder treatment enrollment) for 6 weeks. |
| Sparkling water | Other | Other: Sparkling waterParticipants will receive sparkling water (volume matching alcohol volume intake prior to alcohol use disorder treatment enrollment) for 6 weeks. |
Who may qualify
- Ages
- 21 to 89 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- living in California and provide a California mailing address (to ship study materials to)
- consuming ≤42 alcoholic beverages per week (as we seek to provide an equal count of the substitute beverage and budgetary restrictions prevent an amount greater than that)
- having alcohol use disorder documented with ≥2 symptoms on the Alcohol Symptom Checklist
- being enrolled in Ria Health treatment
- having English language fluency
Key exclusion criteria (1 listed)
- Individuals will be excluded at the online screener survey stage if they do not meet all of the inclusion criteria.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Non-alcoholic beerParticipants will receive non-alcoholic beers and will be encouraged to consume the beverages to the extent they find useful/desirable during the 6-week study period. | Other | Non-alcoholic beer |
| Sparkling waterParticipants will receive sparkling water and will be encouraged to consume the beverages to the extent they find useful/desirable during the 6-week study period. | Other | Sparkling water |
Primary outcome
Participant Beverage Satisfaction (Acceptability)
Time frame: Assessed at the end of week 6
"How satisfied were you with the beverages you received in this study?" with 5-pt scale response options ranging from "Very Unsatisfied" to "Very Satisfied." Higher scores [split by condition] will indicate greater acceptability.
Participant Intention to Consume Assigned Beverage in the Future (Acceptability)
Time frame: Assessed at the end of week 6
"Do you intend to consume the beverage type you received in the future?" with 5-pt scale response options ranging from "Definitely not" to "Definitely." Higher scores [split by condition] will indicate greater acceptability.
Participant Likelihood of Recommending Beverage (Acceptability)
Time frame: Assessed at the end of week 6
"Would you recommend the use of the beverage type you received for people who have alcohol use disorder?" with 5-pt scale response options ranging from "Definitely not" to "Definitely." Higher scores [split by condition] will indicate greater acceptability.
Screened Out of Contacted (Feasibility)
Time frame: Beginning of recruitment to end of recruitment (approximately 3-6 months)
Percentage of participants who completed the screening measure out of those who were contacted. Higher percentage will indicate greater feasibility.
Eligible Out of Screened (Feasibility)
Time frame: Beginning of recruitment to end of recruitment (approximately 3-6 months)
Percentage of participants who screen eligible out of those who were screened. Higher percentage will indicate greater feasibility.
Enrolled Out of Eligible (Feasibility)
Time frame: Beginning of recruitment to end of recruitment (approximately 3-6 months)
Percentage of participants who enrolled out of those who screened eligible. Higher percentage will indicate greater feasibility.
Retention (Feasibility)
Time frame: Beginning of recruitment to end of data collection (approximately 3-6 months)
Percentage of participants who completed the study out of those who enrolled. Higher percentage [split by condition] will indicate greater feasibility.
Perception of Beverage Supply (Feasibility)
Time frame: Assessed at the end of week 6
Percentage of participants whose response to "How was the supply of beverages you received throughout the study?" is "just right" [as opposed to "too little" or "too much"]. Higher percentage [split by condition] will indicate greater feasibility.
8 secondary outcomes
Average Blood Alcohol Content Across 6 Weeks
Time frame: Study weeks 1-6
Change in Blood Alcohol Content Across 6 Weeks
Time frame: Treatment entry to week 6
Average Number of Days with Breathalyzer Readings
Time frame: Assessed at 6 weeks.
Median Number of Breathalyzer Readings Among Days with Readings
Time frame: Assessed at 6 weeks.
Change in Reported Alcohol Use
Time frame: Baseline to 6 weeks.
Perceived Change in Craving
Time frame: Assessed at 6 weeks.
Perceived Change in Alcohol Use
Time frame: Assessed at 6 weeks.
Perceived Impact of Beverages on Recovery
Time frame: Assessed at 6 weeks.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Jul 2026.
- Individual participant dataSharing planned: Yes. Data will be uploaded to the NIAAA data archive
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Molly A Bowdring, PhD principal investigator
Stanford University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Non-alcoholic beer and Sparkling water in people with Alcohol Use Disorder (AUD), run by Stanford University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 20 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Participant Beverage Satisfaction (Acceptability) (time frame: Assessed at the end of week 6). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Jul 2026.