CancerNCT07454330
Study of a Support Program for Quality of Life in Chinese Cancer Patients and Survivors
A study testing Cancer Education, Meaning-Centered Counseling and Peer Support in people with Cancer and Survivorship, run by Memorial Sloan Kettering Cancer Center at 7 sites in United States.
Trial summary
The purpose of this study is to evaluate different combinations of cancer education sessions, counseling sessions, and peer support meetings developed for Chinese cancer patients and survivors. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Cancer, Survivorship
- What is being tested?
- Cancer Education, Meaning-Centered Counseling and Peer Support
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 64 participants
- Where
- 7 sitesUnited States
- Study dates
- 27 Feb 2026to Feb 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosed with cancer (any type/stage) (per EMR for MSK patients or self-report for external participants) within the last 5 years
- Age ≥ 18 years (per EMR for MSK patients or self-report for external participants)
- Self-Report Criteria:
- Of Chinese descent
- Speaks Mandarin "well" or "very well"
- Moderately low HRQOL (<70 FACT-G score)4, 48
Show all 9Show fewer
- Resides in New York or New Jersey
- Agrees to participate via telehealth (video or phone)
- Agrees to be audio-recorded
Who cannot join
- Self-Report Criteria:
- Per PI determination, requires a higher level of care for current passive or active suicidal ideation than current protocol is able to provide. If a participant receives a score of > 0 on item 9 of the PHQ-9,5 they will be referred to study PI for further evaluation using the Columbia-Suicide Severity Rating Scale. They will be excluded from participation in this study if there is presence of suicidal risk, determined by affirmative response(s) on the Columbia-Suicide Severity Rating Scale (C-SSRS)
- Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"
- Cognitive impairment (Montreal Cognitive Assessment 5 Minute - telephone version with a score < 12)
- Per consenting professional determination, unable to understand the informed consent procedure
- Participation in study #14-076: Adaptation of Individual Meaning-Centered Psychotherapy for Chinese immigrant cancer patients)
- Currently receiving/have received psychotherapy/counseling/peer support within the last 6 months (patients being treated solely with psychotropic medications will not be excluded if they are not receiving psychotherapy/counseling/peer support)
Trial locations and contacts
7 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Jennifer Leng, MD, MPH contact
7 sites in 1 country
United States7 sites, 7 recruiting
- Recruiting
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge, New Jersey, 07920
Florence Lui, PhD, 646-888-8375
- Recruiting
Memorial Sloan Kettering Cancer Center Suffolk- Commack (All Protocol Activities)
Commack, New York, 11725
Florence Lui, PhD, 646-888-8375
- Recruiting
Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, New York, 10604
Florence Lui, PhD, 646-888-8375
- Recruiting
Memorial Sloan Kettering Monmouth (All Protocol Activities)
Middletown, New Jersey, 07748
Florence Lui, PhD, 646-888-8375
- Recruiting
Memorial Sloan Kettering Bergen (All Protocol Activities)
Montvale, New Jersey, 07645
Florence Lui, PhD, 646-888-8375
- Recruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065
Florence Lui, PhD, 646-888-8375
Jennifer Leng, MD, MPH, 646-888-8057
- Recruiting
Memorial Sloan Kettering Nassau (All Protocol Activities)
Uniondale, New York, 11553
Florence Lui, PhD, 646-888-8375
About this study
Official title: A Multicomponent Support Program to Enhance Quality of Life in Chinese Cancer Patients and Survivors (MSP-CCS): Pilot Optimization Trial and Implementation Outcomes
The purpose of this study is to evaluate different combinations of cancer education sessions, counseling sessions, and peer support meetings developed for Chinese cancer patients and survivors. The researchers will look at whether the combinations are practical and effective, and how they impact participants' quality of life.
- Conditions
- Cancer, Survivorship
- Being tested
- Cancer Education, Meaning-Centered Counseling, Peer Support, Enhanced Standard Care
- Keywords
- Chinese, Quality of Life, Patients, Survivors, 26-025
- Medical subject headings
- Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cancer EducationOther
Cancer Education on side effects and their management, treatment options, advance care planning, and survivorship. Each session will last about 30-60 minutes and will be completed over the phone or by video call.
Meaning-Centered CounselingOther
Meaning-centered counseling aims to activate culturally relevant meaning-focused coping strategies in Chinese-speaking patients and survivors (CCS). Each session will last about 45-60 minutes and will be completed over the phone or by video call.
Peer SupportOther
Peer support aims to increase social support for CCS to decrease cancer stigma, which has been associated with greater psychological distress, especially among less acculturated Chinese immigrant CCS. The meetings will include up to 6-8 Mandarin-speaking patients and survivors and will last about 90 minutes.
Enhanced Standard CareOther
enhanced standard care ( written cancer information materials in Chinese and referral to counseling)
| Study group | Role | What they receive |
|---|---|---|
| 1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care | Experimental | All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.Counseling sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings. Receives: Other: Cancer Education; Other: Meaning-Centered Counseling; Other: Peer Support; Other: Enhanced Standard Care |
| 2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care | Experimental | All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.Counseling sessions, will have 3 weekly sessions. Receives: Other: Cancer Education; Other: Meaning-Centered Counseling; Other: Enhanced Standard Care |
| 3 - Cancer Education + Peer Support + Enhanced Standard Care | Experimental | All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings. Receives: Other: Cancer Education; Other: Peer Support; Other: Enhanced Standard Care |
| 4 - Cancer Education + Enhanced Standard Care | Experimental | All participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions. Receives: Other: Cancer Education; Other: Enhanced Standard Care |
| 5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care | Experimental | All participants will also receive cancer information materials and resources.Counseling sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings Receives: Other: Meaning-Centered Counseling; Other: Peer Support; Other: Enhanced Standard Care |
| 6 - Meaning-Centered Counseling- + Enhanced Standard Care | Experimental | All participants will also receive cancer information materials and resources. Counseling sessions, will have 3 weekly sessions. Receives: Other: Meaning-Centered Counseling; Other: Enhanced Standard Care |
| 7 - Peer Support + Enhanced Standard Care | Experimental | All participants will also receive cancer information materials and resources. Peer support meetings, will have 3 monthly meetings Receives: Other: Peer Support; Other: Enhanced Standard Care |
| 8 - Enhanced Standard Care | Active comparator | All participants will also receive cancer information materials and resources. Receives: Other: Enhanced Standard Care |
What is being measured
The primary outcome is the main question the study is designed to answer.
Proportion of eligible participants who enroll in the trial.
Measured: 2 years
Proportion of participants who complete treatment
Proportion of assessments that are completed, with completion defined as submitting the assessment with a minimum of the FACT-G completed.
Measured: up to 24 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Mar 2026
- Study start27 Feb 2026
- Primary completionFeb 2028 (estimated)
- Study completionFeb 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CancerStudies of the same condition, open and under way.
- More trials run by Memorial Sloan Kettering Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Factorial
- Model description
- Using a 2x2x2 factorial design. Participants will be randomized to receive a combination of one or more culturally tailored telehealth-delivered intervention components.
- Masking
- None (open label)
- Enrolment
- 64 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Sponsor type
- University, hospital or other
- Collaborators
- American Cancer Society, Inc., Brooklyn College Cancer Center, Herald Cancer Association
- Responsible party
- Sponsor
- Investigators
- Florence Lui, PhD, Principal investigator, Memorial Sloan Kettering Cancer Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07454330
- Sponsor's protocol ID
- 26-025
- Status last verified
- Nov 2026
- First submitted
- 2 Mar 2026
- Last updated
- 6 Nov 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.
Study at a glance
From the registry record, last updated by the sponsor on 6 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Multicomponent Support Program to Enhance Quality of Life in Chinese Cancer Patients and Survivors (MSP-CCS): Pilot Optimization Trial and Implementation Outcomes
- ClinicalTrials.gov ID
- NCT07454330
- Acronym / sponsor ID
- 26-025
- Conditions
- Cancer, Survivorship
- Keywords
- Chinese, Quality of Life, Patients, Survivors, 26-025
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 64 participants (estimated)
- Lead sponsor
- Memorial Sloan Kettering Cancer CenterUniversity, hospital or other
- Collaborators
- American Cancer Society, Inc., Brooklyn College Cancer Center, Herald Cancer Association
- Study start
- 27 Feb 2026 (actual)
- Primary completion
- Feb 2028 (estimated)
- Study completion
- Feb 2028 (estimated)
- First posted
- 6 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to evaluate different combinations of cancer education sessions, counseling sessions, and peer support meetings developed for Chinese cancer patients and survivors. The researchers will look at whether the combinations are practical and effective, and how they impact participants' quality of life.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- None (open label)
- Number of arms
- 8
- Model description
- Using a 2x2x2 factorial design. Participants will be randomized to receive a combination of one or more culturally tailored telehealth-delivered intervention components.
| Arm | Type | Receives |
|---|---|---|
| 1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care | Experimental | Other: Cancer Education, Other: Meaning-Centered Counseling, Other: Peer Support, Other: Enhanced Standard CareAll participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.Counseling sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings. |
| 2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care | Experimental | Other: Cancer Education, Other: Meaning-Centered Counseling, Other: Enhanced Standard CareAll participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions.Counseling sessions, will have 3 weekly sessions. |
| 3 - Cancer Education + Peer Support + Enhanced Standard Care | Experimental | Other: Cancer Education, Other: Peer Support, Other: Enhanced Standard CareAll participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings. |
| 4 - Cancer Education + Enhanced Standard Care | Experimental | Other: Cancer Education, Other: Enhanced Standard CareAll participants will also receive cancer information materials and resources. Cancer education sessions, will have 3 weekly sessions. |
| 5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care | Experimental | Other: Meaning-Centered Counseling, Other: Peer Support, Other: Enhanced Standard CareAll participants will also receive cancer information materials and resources.Counseling sessions, will have 3 weekly sessions. Peer support meetings, will have 3 monthly meetings |
| 6 - Meaning-Centered Counseling- + Enhanced Standard Care | Experimental | Other: Meaning-Centered Counseling, Other: Enhanced Standard CareAll participants will also receive cancer information materials and resources. Counseling sessions, will have 3 weekly sessions. |
| 7 - Peer Support + Enhanced Standard Care | Experimental | Other: Peer Support, Other: Enhanced Standard CareAll participants will also receive cancer information materials and resources. Peer support meetings, will have 3 monthly meetings |
| 8 - Enhanced Standard Care | Active comparator | Other: Enhanced Standard CareAll participants will also receive cancer information materials and resources. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (9 listed)
- Diagnosed with cancer (any type/stage) (per EMR for MSK patients or self-report for external participants) within the last 5 years
- Age ≥ 18 years (per EMR for MSK patients or self-report for external participants)
- Of Chinese descent
- Speaks Mandarin "well" or "very well"
- Moderately low HRQOL (<70 FACT-G score)4, 48
Key exclusion criteria (7 listed)
- Per PI determination, requires a higher level of care for current passive or active suicidal ideation than current protocol is able to provide. If a participant receives a score of > 0 on item 9 of the PHQ-9,5 they will be referred to study PI for further evaluation using the Columbia-Suicide Severity Rating Scale. They will be excluded from participation in this study if there is presence of suicidal risk, determined by affirmative response(s) on the Columbia-Suicide Severity Rating Scale (C-SSRS)
- Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"
- Cognitive impairment (Montreal Cognitive Assessment 5 Minute - telephone version with a score < 12)
- Per consenting professional determination, unable to understand the informed consent procedure
- Participation in study #14-076: Adaptation of Individual Meaning-Centered Psychotherapy for Chinese immigrant cancer patients)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cancer EducationCancer Education on side effects and their management, treatment options, advance care planning, and survivorship. Each session will last about 30-60 minutes and will be completed over the phone or by video call. | Other | 1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care, 2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care, 3 - Cancer Education + Peer Support + Enhanced Standard Care, 4 - Cancer Education + Enhanced Standard Care |
| Meaning-Centered CounselingMeaning-centered counseling aims to activate culturally relevant meaning-focused coping strategies in Chinese-speaking patients and survivors (CCS). Each session will last about 45-60 minutes and will be completed over the phone or by video call. | Other | 1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care, 2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care, 5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care, 6 - Meaning-Centered Counseling- + Enhanced Standard Care |
| Peer SupportPeer support aims to increase social support for CCS to decrease cancer stigma, which has been associated with greater psychological distress, especially among less acculturated Chinese immigrant CCS. The meetings will include up to 6-8 Mandarin-speaking patients and survivors and will last about 90 minutes. | Other | 1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care, 3 - Cancer Education + Peer Support + Enhanced Standard Care, 5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care, 7 - Peer Support + Enhanced Standard Care |
| Enhanced Standard Careenhanced standard care ( written cancer information materials in Chinese and referral to counseling) | Other | 1 - Cancer Education + Meaning-Centered Counseling + Peer Support + Enhanced Standard Care, 2 - Cancer Education + Meaning-Centered Counseling + Enhanced Standard Care, 3 - Cancer Education + Peer Support + Enhanced Standard Care, 4 - Cancer Education + Enhanced Standard Care, 5 - Meaning-Centered Counseling + Peer Support + Enhanced Standard Care, 6 - Meaning-Centered Counseling- + Enhanced Standard Care, 7 - Peer Support + Enhanced Standard Care, 8 - Enhanced Standard Care |
Primary outcome
Proportion of eligible participants who enroll in the trial.
Time frame: 2 years
Proportion of participants who complete treatment
Time frame: up to 24 weeks
Proportion of assessments that are completed, with completion defined as submitting the assessment with a minimum of the FACT-G completed.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Nov 2026.
- Memorial Sloan Kettering Cancer CenterLink provided by the sponsor.
- Individual participant dataSharing planned: Yes. Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Jennifer Leng, MD, MPH contact
Florence Lui, PhD principal investigator
Memorial Sloan Kettering Cancer Center
7 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cancer Education, Meaning-Centered Counseling and Peer Support in people with Cancer and Survivorship, run by Memorial Sloan Kettering Cancer Center at 7 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 6 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 7 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Florence Lui, PhD (646-888-8375, luif@mskcc.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Proportion of eligible participants who enroll in the trial. (time frame: 2 years). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Nov 2026.