Wound Infection Post-TraumaticNCT07456072
Effectiveness of Chlorhexidine Impregnated Gauze Versus Povidone Iodine Dressing in Post Trauma Wound Care
A study testing Chlorhexidine impregnated paraffin gauze and Povidone iodine dressing in people with Wound Infection Post-Traumatic and Wound Healing, run by Pakistan Institute of Medical Sciences at 1 site in Pakistan.
Trial summary
To compare rate of infection and wound healing between chlorhexidine impregnated paraffin gauze and dry povidone-iodine dressings in post-traumatic wounds. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Wound Infection Post-Traumatic, Wound Healing
- What is being tested?
- Chlorhexidine impregnated paraffin gauze and Povidone iodine dressing
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 176 participants
- Where
- 1 sitePakistan
- Study dates
- 13 May 2026to 12 Aug 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients 18-65 years of age with acute post-trauma wounds.
- Wounds that are clean contaminated at presentation.
Who cannot join
- Patients with the known allergies to Chlorhexidine or Povidone-Iodine.
- Chronic wounds or those with underlying chronic conditions, such as diabetes.
- Patients with compromised immune systems.
- Pregnant females
Trial locations and contacts
1 site in 1 country.
About this study
To compare rate of infection and wound healing between chlorhexidine impregnated paraffin gauze and dry povidone-iodine dressings in post-traumatic wounds.
- Conditions
- Wound Infection Post-Traumatic, Wound Healing
- Being tested
- Chlorhexidine impregnated paraffin gauze, Povidone iodine dressing
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Chlorhexidine impregnated paraffin gauzeProcedure or surgery
Paraffin gauze impregnated with 0.2 % chlorhexidine
Povidone iodine dressingProcedure or surgery
Standard povidone iodine dressing
| Study group | Role | What they receive |
|---|---|---|
| Povidone iodine group | Active comparator | Not described Receives: Procedure: Povidone iodine dressing |
| Chlorhexidine impregnated paraffin gauze group | Experimental | Not described Receives: Procedure: Chlorhexidine impregnated paraffin gauze |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in infection rate
Measured: 3 months
Secondary outcomes (1)
Change in Wound healing
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Mar 2026
- Study start13 May 2026
- Primary completion12 Aug 2026
- Study completion12 Aug 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Wound Infection Post-TraumaticStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 176 participants (actual)
Sponsor and investigators
- Lead sponsor
- Pakistan Institute of Medical Sciences
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Ibrahim Nasir Idrees, Pakistan Institute of Medical Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07456072
- Sponsor's protocol ID
- No.F.1-1/2015/ERB/SZABMU/1482
- Status last verified
- Mar 2026
- First submitted
- 26 Feb 2026
- Last updated
- 17 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Chlorhexidine Impregnated Gauze Versus Povidone Iodine Dressing in Post Trauma Wound Care
- ClinicalTrials.gov ID
- NCT07456072
- Acronym / sponsor ID
- No.F.1-1/2015/ERB/SZABMU/1482
- Conditions
- Wound Infection Post-Traumatic, Wound Healing
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 176 participants (actual)
- Lead sponsor
- Pakistan Institute of Medical SciencesOther government
- Study start
- 13 May 2026 (actual)
- Primary completion
- 12 Aug 2026 (actual)
- Study completion
- 12 Aug 2026 (actual)
- First posted
- 6 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To compare rate of infection and wound healing between chlorhexidine impregnated paraffin gauze and dry povidone-iodine dressings in post-traumatic wounds.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Povidone iodine group | Active comparator | Procedure: Povidone iodine dressing |
| Chlorhexidine impregnated paraffin gauze group | Experimental | Procedure: Chlorhexidine impregnated paraffin gauze |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Patients 18-65 years of age with acute post-trauma wounds.
- Wounds that are clean contaminated at presentation.
Key exclusion criteria (4 listed)
- Patients with the known allergies to Chlorhexidine or Povidone-Iodine.
- Chronic wounds or those with underlying chronic conditions, such as diabetes.
- Patients with compromised immune systems.
- Pregnant females
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Chlorhexidine impregnated paraffin gauzeParaffin gauze impregnated with 0.2 % chlorhexidine | Procedure or surgery | Chlorhexidine impregnated paraffin gauze group |
| Povidone iodine dressingStandard povidone iodine dressing | Procedure or surgery | Povidone iodine group |
Primary outcome
Change in infection rate
Time frame: 3 months
1 secondary outcome
Change in Wound healing
Time frame: 3 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Chlorhexidine impregnated paraffin gauze and Povidone iodine dressing in people with Wound Infection Post-Traumatic and Wound Healing, run by Pakistan Institute of Medical Sciences at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in infection rate (time frame: 3 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2026.