Impacted ToothImmediateIMPNCT07456553
Impacted Tooth With Immediate Implant Placement
A study testing Implantology in people with Impacted Tooth, run by University of Bari Aldo Moro at 1 site in Italy.
Trial summary
This is a prospective study, in which there are involved four clinical cases of surgical extraction of impacted maxillary canines followed by immediate implant placement and immediate screw-retained temporary crown using a full-digital workflow that included performing a CBCT, an intraoral scan, AI-assisted… Read more about this study
- Who is it for?
- Ages 18 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Impacted Tooth
- What is being tested?
- Implantology
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 5 participants
- Where
- 1 siteItaly
- Study dates
- 1 Jan 2024to 1 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Refuse Orthodontic treatments
- Patients had to be healthy according to System of the American Society of Anesthesiology (ASA) and aged 18 years or older
- No general medical condition representing a contraindication to implant therapy
- minimum 2 missing teeth in the maxilla or mandible from the canine to the second molar
- No periodontal disease (periodontal probing depth <4 mm) or treated periodontitis
- Good oral hygiene (full mouth plaque index<25%)
- Adequate control of inflammation (full mouth bleeding on probing<25%)
Who cannot join
- smoking of more than 15 cigarettes a day
- untreated periodontal disease
- pregnancy or breastfeeding at date of inclusion
- acute infections
- keratinized mucosal tissue less than 2 mm
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Surgical Extraction of an Impacted Canine and Immediate Implant Placement: A Prosthetically Guided Digital Approach
This is a prospective study, in which there are involved four clinical cases of surgical extraction of impacted maxillary canines followed by immediate implant placement and immediate screw-retained temporary crown using a full-digital workflow that included performing a CBCT, an intraoral scan, AI-assisted segmentation, a virtual wax-up, and the design of a surgical guide and a 30° angled abutment. Then, the follow-up lasting two years is performed to verify the functional and esthetical outcomes. The patients included in this report are part of an ongoing clinical trial, and the complete data set will be published separately upon study completion. The aims is to present clinical outcomes and synthesize evidence comparing placing implant to avoid buccal augmentation using angles abutments versus performing guided bone regeneration (GBR) to allow ideal implant placement with straight abutments, and to evaluate the risk of abutment screw loosening.
- Conditions
- Impacted Tooth
- Being tested
- Implantology
- Keywords
- Implantology, Prosthesis, Fixed Crown
- Medical subject headings
- Tooth, Impacted
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ImplantologyProcedure or surgery
Following local anesthetic infiltration and a minimally invasive access, the atraumatic extraction of the impacted canine is performed, preserving the vestibular soft and bone tissues. The implant site is then prepared, and the implant is placed using the surgical guide, with the required insertion torque to achieve primary implant stability.
| Study group | Role | What they receive |
|---|---|---|
| Patients with impacted tooth | Experimental | Patient with impacted Maxillary Canine. Receives: Procedure: Implantology |
What is being measured
The primary outcome is the main question the study is designed to answer.
ISQ
Implant stability quotient. ( 0 - 100)
Measured: At implant insertion and after 3 months
Periimplant chart
Probing the implant in 6 site.
Measured: 3 month after implant insertion, 1 year, 2 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Mar 2026
- Study start1 Jan 2024
- Primary completion1 Mar 2026
- Study completion1 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Impacted ToothStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 5 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Bari Aldo Moro
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Giuseppe D'Albis, University of Bari Aldo Moro
- Investigators
- Francesco Colacicco, Principal investigator, University of Bari Aldo MoroGiuseppe D'Albis, Dr., Principal investigator, University of Bari Aldo MoroSaverio Capodiferro, Prof. Dr., Study director, University of Bari Aldo MoroMassimo Corsalini, Prof. Dr., Study director, University of Bari Aldo Moro
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07456553
- Sponsor's protocol ID
- TiltedImplant2026
- Acronym
- ImmediateIMP
- Status last verified
- Mar 2026
- First submitted
- 2 Mar 2026
- Last updated
- 11 Mar 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Surgical Extraction of an Impacted Canine and Immediate Implant Placement: A Prosthetically Guided Digital Approach
- ClinicalTrials.gov ID
- NCT07456553
- Acronym / sponsor ID
- ImmediateIMP / TiltedImplant2026
- Conditions
- Impacted Tooth
- Keywords
- Implantology, Prosthesis, Fixed Crown
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 5 participants (actual)
- Lead sponsor
- University of Bari Aldo MoroUniversity, hospital or other
- Study start
- 1 Jan 2024 (actual)
- Primary completion
- 1 Mar 2026 (actual)
- Study completion
- 1 Mar 2026 (actual)
- First posted
- 6 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a prospective study, in which there are involved four clinical cases of surgical extraction of impacted maxillary canines followed by immediate implant placement and immediate screw-retained temporary crown using a full-digital workflow that included performing a CBCT, an intraoral scan, AI-assisted segmentation, a virtual wax-up, and the design of a surgical guide and a 30° angled abutment. Then, the follow-up lasting two years is performed to verify the functional and esthetical outcomes. The patients included in this report are part of an ongoing clinical trial, and the complete data set will be published separately upon study completion. The aims is to present clinical outcomes and synthesize evidence comparing placing implant to avoid buccal augmentation using angles abutments versus performing guided bone regeneration (GBR) to allow ideal implant placement with straight abutments, and to evaluate the risk of abutment screw loosening.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patients with impacted tooth | Experimental | Procedure: ImplantologyPatient with impacted Maxillary Canine. |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- Refuse Orthodontic treatments
- Patients had to be healthy according to System of the American Society of Anesthesiology (ASA) and aged 18 years or older
- No general medical condition representing a contraindication to implant therapy
- minimum 2 missing teeth in the maxilla or mandible from the canine to the second molar
- No periodontal disease (periodontal probing depth <4 mm) or treated periodontitis
Key exclusion criteria (5 listed)
- smoking of more than 15 cigarettes a day
- untreated periodontal disease
- pregnancy or breastfeeding at date of inclusion
- acute infections
- keratinized mucosal tissue less than 2 mm
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ImplantologyFollowing local anesthetic infiltration and a minimally invasive access, the atraumatic extraction of the impacted canine is performed, preserving the vestibular soft and bone tissues. The implant site is then prepared, and the implant is placed using the surgical guide, with the required insertion torque to achieve primary implant stability. | Procedure or surgery | Patients with impacted tooth |
Primary outcome
ISQ
Time frame: At implant insertion and after 3 months
Implant stability quotient. ( 0 - 100)
Periimplant chart
Time frame: 3 month after implant insertion, 1 year, 2 years
Probing the implant in 6 site.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Mar 2026.
Related trials for Impacted Tooth
RecruitingObservational study
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
Stomatognatic, Tooth Diseases
Not yet recruiting
mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System
HIV Prevention, Substance Use
Not yet recruiting
Immediate vs Conventional Loading With Different Crown Materials on Immediately Placed Single Implants
Partial Edentulism, Dental Implant
Recruiting
Effect of Alpha-Band Binaural Beats on Stress and Recovery in Third Molar Surgery
Dental Anxiety, Postoperative Pain
Not yet recruiting
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth
Accelerate Tooth Movement
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Francesco Colacicco principal investigator
University of Bari Aldo Moro
Giuseppe D'Albis, Dr. principal investigator
University of Bari Aldo Moro
Saverio Capodiferro, Prof. Dr. study director
University of Bari Aldo Moro
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Implantology in people with Impacted Tooth, run by University of Bari Aldo Moro at 1 site in Italy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
ISQ (time frame: At implant insertion and after 3 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Mar 2026.