CancerEHCancerNCT07457112
EHealth Educational Intervention to Improve Self-Management and Coping Behaviors Among Cancer Patients
A study testing Structured eHealth Educational Intervention in people with Cancer and Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), run by Zagazig University at 1 site in Egypt.
Trial summary
Brief Summary This study evaluates the effectiveness of a structured eHealth-based educational and support intervention in improving self-management practices and psychological coping behaviors among adult cancer patients. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Cancer, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)
- What is being tested?
- Structured eHealth Educational Intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 212 participants
- Where
- 1 siteEgypt
- Study dates
- 30 Nov 2023to 26 Nov 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Male and female adult cancer patients
- Diagnosed with cancer and currently receiving chemotherapy
- Able to read and understand Arabic
- Own a mobile phone and able to use online applications (e.g., Zoom or similar platforms)
- Willing to participate in the eHealth educational program
- Provided informed consent to participate in the study
Who cannot join
- Patients with severe cognitive impairment or psychiatric disorders that interfere with participation
- Patients with critical health conditions preventing attendance in the intervention sessions
- Patients who participated in similar structured educational or coping programs during the study period
- Patients unwilling to complete baseline or follow-up assessments
Trial locations and contacts
1 site in 1 country.
About this study
Official title: A Controlled Evaluation of EHealth Interventions for Self-Management and Psychological Coping in Cancer Patients
Brief Summary This study evaluates the effectiveness of a structured eHealth-based educational and support intervention in improving self-management practices and psychological coping behaviors among adult cancer patients. Using a quasi-experimental pretest-posttest design with study and control groups, the intervention integrates online education, interactive sessions, and digital communication platforms to enhance symptom management, emotional regulation, and adaptive coping strategies. The findings aim to inform scalable digital health solutions in oncology care.
Read the detailed description
Cancer patients often experience complex physical and psychological challenges related to disease progression and treatment side effects. eHealth interventions offer accessible, personalized, and cost-effective tools that support patient engagement, self-efficacy, and coping.
This study applies a structured eHealth intervention grounded in Self-Determination Theory to enhance autonomy, competence, and relatedness among cancer patients. The intervention includes synchronous online sessions, digital educational materials, and ongoing communication via mobile platforms over six weeks. Outcomes are measured using validated self-management and coping scales before and after the intervention. The study contributes evidence on the effectiveness of digital health interventions within the Saudi Arabian healthcare context.
- Conditions
- Cancer, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)
- Being tested
- Structured eHealth Educational Intervention
- Keywords
- EHealth, Self-Management, Educational Intervention
- Medical subject headings
- Neoplasms, Colonic Neoplasms, Breast Neoplasms, Lymphoma, Multiple Myeloma
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Structured eHealth Educational InterventionBehavioural
The intervention consists of structured online educational sessions delivered via video conferencing platforms, supported by digital educational materials including videos and informational resources. The program incorporates scenario-based discussions, peer interaction, and continuous follow-up communication. The content focuses on symptom self-management, emotional regulation, and adaptive coping strategies for cancer patients.
| Study group | Role | What they receive |
|---|---|---|
| Structured eHealth Intervention Group | Experimental | Participants receive a structured eHealth educational intervention program delivered over six weeks in addition to routine care. The program focuses on enhancing self-management skills and psychological coping strategies among cancer patients. Receives: Behavioral: Structured eHealth Educational Intervention |
| Routine Care Control Group | No intervention | Participants receive routine care provided by the healthcare facility without additional eHealth educational intervention. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Symptom-Management Self-Efficacy Score
Measured using the Symptom-Management Self-Efficacy Scale (SMSE) developed by Liang et al. (2015). The scale consists of 27 items across three subscales: acquiring problem-solving (7 items), managing chemotherapy-related symptoms (15 items), and managing emotional and interpersonal disturbance (5 items). Each item is scored on an 11-point scale ranging from 0 (not at all confident) to 10 (completely confident). The total possible score ranges from 0 to 270. Higher scores indicate greater perceived self-efficacy in symptom management.
Measured: Baseline and 6 weeks (immediately post-intervention)
Secondary outcomes (2)
Change in Coping Behavior Score
Measured using the Jalowiec Coping Scale developed by Jalowiec and Powers (1981). The scale includes 40 items divided into two subscales: affective-oriented coping (25 items) and problem-oriented coping (15 items). Items are rated on a 5-point Likert scale ranging from 0 (never) to 4 (always). The total possible score ranges from 0 to 160. Higher scores indicate greater use of coping strategies.
Measured: Baseline and 6 weeks (post-intervention)
Correlation Between Self-Efficacy and Coping Scores
Assessment of the correlation between total Symptom-Management Self-Efficacy Scale scores and total Jalowiec Coping Scale scores at post-intervention.
Measured: 6 weeks (post-intervention)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Mar 2026
- Study start30 Nov 2023
- Primary completion26 Feb 2024
- Study completion26 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for CancerStudies of the same condition, open and under way.
- More trials run by Zagazig UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants receive a structured eHealth intervention over 6 weeks, including: * Online educational sessions (Zoom / Google Meet) * Digital learning materials (videos, posters, pamphlets) * Scenario-based discussions and peer interaction * Continuous communication and reminders via WhatsApp * Focus areas: symptom self-management, emotional regulation, adaptive coping strategies Control Group Participants receive standard educational materials only (limited sessions without interactive eHealth components).
- Masking
- None (open label)
- Enrolment
- 212 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zagazig University
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Manal Saleh Moustafa Saleh, Zagazig University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07457112
- Sponsor's protocol ID
- SU-ERC-2023-011-EH
- Acronym
- EHCancer
- Status last verified
- Feb 2024
- First submitted
- 25 Feb 2026
- Last updated
- 9 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Saleh MSM, Aly Salem SG, Khader KA, Fathi RH, Elsabahy HE, Dailah HG, Alshamry HMF, Mohamed SMN, Ahmed EAG, Hamed LA. A Randomized Controlled Trial: eHealth Interventions for Self-Management and Psychological Coping in Cancer Patients. Healthcare (Basel). 2026 Aug 4;14(15):2391. doi: 10.3390/healthcare14152391.
PubMed 42588359
Study at a glance
From the registry record, last updated by the sponsor on 9 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Controlled Evaluation of EHealth Interventions for Self-Management and Psychological Coping in Cancer Patients
- ClinicalTrials.gov ID
- NCT07457112
- Acronym / sponsor ID
- EHCancer / SU-ERC-2023-011-EH
- Conditions
- Cancer, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)
- Keywords
- EHealth, Self-Management, Educational Intervention
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 212 participants (actual)
- Lead sponsor
- Zagazig UniversityOther government
- Study start
- 30 Nov 2023 (actual)
- Primary completion
- 26 Feb 2024 (actual)
- Study completion
- 26 Nov 2025 (actual)
- First posted
- 9 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Brief Summary This study evaluates the effectiveness of a structured eHealth-based educational and support intervention in improving self-management practices and psychological coping behaviors among adult cancer patients. Using a quasi-experimental pretest-posttest design with study and control groups, the intervention integrates online education, interactive sessions, and digital communication platforms to enhance symptom management, emotional regulation, and adaptive coping strategies. The findings aim to inform scalable digital health solutions in oncology care.
Detailed description
Cancer patients often experience complex physical and psychological challenges related to disease progression and treatment side effects. eHealth interventions offer accessible, personalized, and cost-effective tools that support patient engagement, self-efficacy, and coping.
This study applies a structured eHealth intervention grounded in Self-Determination Theory to enhance autonomy, competence, and relatedness among cancer patients. The intervention includes synchronous online sessions, digital educational materials, and ongoing communication via mobile platforms over six weeks. Outcomes are measured using validated self-management and coping scales before and after the intervention. The study contributes evidence on the effectiveness of digital health interventions within the Saudi Arabian healthcare context.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants receive a structured eHealth intervention over 6 weeks, including: * Online educational sessions (Zoom / Google Meet) * Digital learning materials (videos, posters, pamphlets) * Scenario-based discussions and peer interaction * Continuous communication and reminders via WhatsApp * Focus areas: symptom self-management, emotional regulation, adaptive coping strategies Control Group Participants receive standard educational materials only (limited sessions without interactive eHealth components).
| Arm | Type | Receives |
|---|---|---|
| Structured eHealth Intervention Group | Experimental | Behavioral: Structured eHealth Educational InterventionParticipants receive a structured eHealth educational intervention program delivered over six weeks in addition to routine care. The program focuses on enhancing self-management skills and psychological coping strategies among cancer patients. |
| Routine Care Control Group | No intervention | –Participants receive routine care provided by the healthcare facility without additional eHealth educational intervention. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Male and female adult cancer patients
- Diagnosed with cancer and currently receiving chemotherapy
- Able to read and understand Arabic
- Own a mobile phone and able to use online applications (e.g., Zoom or similar platforms)
- Willing to participate in the eHealth educational program
Key exclusion criteria (4 listed)
- Patients with severe cognitive impairment or psychiatric disorders that interfere with participation
- Patients with critical health conditions preventing attendance in the intervention sessions
- Patients who participated in similar structured educational or coping programs during the study period
- Patients unwilling to complete baseline or follow-up assessments
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Structured eHealth Educational InterventionThe intervention consists of structured online educational sessions delivered via video conferencing platforms, supported by digital educational materials including videos and informational resources. The program incorporates scenario-based discussions, peer interaction, and continuous follow-up communication. The content focuses on symptom self-management, emotional regulation, and adaptive coping strategies for cancer patients. | Behavioural | Structured eHealth Intervention Group |
Primary outcome
Change in Symptom-Management Self-Efficacy Score
Time frame: Baseline and 6 weeks (immediately post-intervention)
Measured using the Symptom-Management Self-Efficacy Scale (SMSE) developed by Liang et al. (2015). The scale consists of 27 items across three subscales: acquiring problem-solving (7 items), managing chemotherapy-related symptoms (15 items), and managing emotional and interpersonal disturbance (5 items). Each item is scored on an 11-point scale ranging from 0 (not at all confident) to 10 (completely confident). The total possible score ranges from 0 to 270. Higher scores indicate greater perceived self-efficacy in symptom management.
2 secondary outcomes
Change in Coping Behavior Score
Time frame: Baseline and 6 weeks (post-intervention)
Correlation Between Self-Efficacy and Coping Scores
Time frame: 6 weeks (post-intervention)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Mar 2026.
- Derived from this study: PubMed 42588359Saleh MSM, Aly Salem SG, Khader KA, Fathi RH, Elsabahy HE, Dailah HG, Alshamry HMF, Mohamed SMN, Ahmed EAG, Hamed LA. A Randomized Controlled Trial: eHealth Interventions for Self-Management and Psychological Coping in Cancer Patients. Healthcare (Basel). 2026 Aug 4;14(15):2391. doi: 10.3390/healthcare14152391.
Related trials for Cancer
Not yet recruitingPhase 1
Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy
Colorectal Neoplasms, Neoplasms
RecruitingPhase 2
Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Active, not recruitingPhase 1/2
Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Low Grade Glioma, Recurrent Childhood Pilocytic Astrocytoma
Enrolling by invitationPhase 2
A Single-Arm Study of Nimotuzumab Combined With NALIRIFOX as First-Line Treatment for Pancreatic Cancer
Pancreatic Cancer Metastatic
Recruiting
Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological Cancers
Gynaecological Cancers, Ovarian Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Structured eHealth Educational Intervention in people with Cancer and Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), run by Zagazig University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Symptom-Management Self-Efficacy Score (time frame: Baseline and 6 weeks (immediately post-intervention)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07457112, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Mar 2026.