Pregnancy-induced HypertensionBCRPIHNCT07464379
Basic and Clinical Research of Pregnancy-Induced Hypertension
An observational study of Pregnancy-induced Hypertension, run by Second Affiliated Hospital of Wenzhou Medical University at 1 site in China.
Trial summary
Collect blood pressure, blood, amniotic fluid, placenta and other samples from normal pregnant women, patients with pregnancy-induced hypertension and those who have experienced miscarriage, and conduct tests on them. Read more about this study
- Who is it for?
- Ages 20 to 50 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Pregnancy-induced Hypertension
- How many people
- 100 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2020to 31 Dec 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 50 years
- Women only
- Healthy volunteers accepted
- Adult
Study population: Healthy parturient women, women who have had miscarriages, patients with pregnancy-induced hypertension
Who may be able to join
- Healthy pregnant women, patients with miscarriage, etc.
Who cannot join
- Heart disease, infections, etc. in pregnant women Uncooperative patients
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
The Second Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, 325000
Qian Wang, PHD, 13587638653, wqian84@163.com
About this study
Official title: Collect Blood Pressure, Blood, Amniotic Fluid, Placenta and Other Samples From Normal Pregnant Women, Patients With Pregnancy-induced Hypertension and Those Who Have Experienced Miscarriage, and Conduct Tests on Them.
Collect blood pressure, blood, amniotic fluid, placenta and other samples from normal pregnant women, patients with pregnancy-induced hypertension and those who have experienced miscarriage, and conduct tests on them.
- Conditions
- Pregnancy-induced Hypertension
- Being tested
- no Intervention
- Medical subject headings
- Hypertension, Pregnancy-Induced
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
no InterventionOther
observation
| Study group | Role | What they receive |
|---|---|---|
| control group | Healthy pregnant women Receives: Other: no Intervention | |
| PIH group | Pregnancy-induced hypertension patients Receives: Other: no Intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
PIH
the content of GPR18 type macrophages
Measured: Early pregnancy：Weeks 1 to 12 (the first to third months of pregnancy) ；mid-pregnancy：Weeks 13 to 27 (the 4th to 6th month of pregnancy) ；post-delivery period：Weeks 28 to 40 (the 7th to 9th months of pregnancy)；the day of delivery。
Secondary outcomes (3)
PIH
Blood pressure
Measured: delivery
PIH
SPM content
Measured: delivery
PIH
Spiral artery morphology
Measured: delivery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Mar 2026
- Study start1 Jan 2020
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pregnancy-induced HypertensionStudies of the same condition, open and under way.
- More trials run by Second Affiliated Hospital of Wenzhou Medical UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Qian Wang, Study chair, The Second Affiliated Hospital of wenzhou Medical University Longwan Branch
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07464379
- Sponsor's protocol ID
- SAHoWMU-CR2025-03-134
- Acronym
- BCRPIH
- Status last verified
- Mar 2026
- First submitted
- 5 Jan 2026
- Last updated
- 11 Mar 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Collect Blood Pressure, Blood, Amniotic Fluid, Placenta and Other Samples From Normal Pregnant Women, Patients With Pregnancy-induced Hypertension and Those Who Have Experienced Miscarriage, and Conduct Tests on Them.
- ClinicalTrials.gov ID
- NCT07464379
- Acronym / sponsor ID
- BCRPIH / SAHoWMU-CR2025-03-134
- Conditions
- Pregnancy-induced Hypertension
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Second Affiliated Hospital of Wenzhou Medical UniversityUniversity, hospital or other
- Study start
- 1 Jan 2020 (actual)
- Primary completion
- 31 Dec 2027 (estimated)
- Study completion
- 31 Dec 2028 (estimated)
- First posted
- 11 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Collect blood pressure, blood, amniotic fluid, placenta and other samples from normal pregnant women, patients with pregnancy-induced hypertension and those who have experienced miscarriage, and conduct tests on them.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| control group | – | Other: no InterventionHealthy pregnant women |
| PIH group | – | Other: no InterventionPregnancy-induced hypertension patients |
Who may qualify
- Ages
- 20 to 50 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Healthy parturient women, women who have had miscarriages, patients with pregnancy-induced hypertension
Key inclusion criteria (1 listed)
- Healthy pregnant women, patients with miscarriage, etc.
Key exclusion criteria (1 listed)
- Heart disease, infections, etc. in pregnant women Uncooperative patients
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| no Interventionobservation | Other | PIH group, control group |
Primary outcome
PIH
Time frame: Early pregnancy：Weeks 1 to 12 (the first to third months of pregnancy) ；mid-pregnancy：Weeks 13 to 27 (the 4th to 6th month of pregnancy) ；post-delivery period：Weeks 28 to 40 (the 7th to 9th months of pregnancy)；the day of delivery。
the content of GPR18 type macrophages
3 secondary outcomes
PIH
Time frame: delivery
PIH
Time frame: delivery
PIH
Time frame: delivery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Qian Wang study chair
The Second Affiliated Hospital of wenzhou Medical University Longwan Branch
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Pregnancy-induced Hypertension, run by Second Affiliated Hospital of Wenzhou Medical University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 11 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Qian Wang, PHD (13587638653, wqian84@163.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
PIH (time frame: Early pregnancy：Weeks 1 to 12 (the first to third months of pregnancy) ；mid-pregnancy：Weeks 13 to 27 (the 4th to 6th month of pregnancy) ；post-delivery period：Weeks 28 to 40 (the 7th to 9th months of pregnancy)；the day of delivery。). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Mar 2026.