Caries AssessmentEcofriendlyNCT07467538
Ecofriendly Versus Nylon Tooth Brushes on Cariogram Outcomes
A study testing Nylon based tooth brush and Ecofriendly toothbrush in people with Caries Assessment and Caries Risk, run by Cairo University at 1 site in Egypt.
Trial summary
The goal of this clinical trial is to evaluate the effectiveness of an eco-friendly toothbrush compared to a conventional nylon-based toothbrush on cariogram parameters in children and adults. It will also assess the impact of toothbrush type on caries risk factors. Read more about this study
- Who is it for?
- Ages 8 to 35 months
- Conditions the study is for
- Caries Assessment, Caries Risk, Oral Health
- What is being tested?
- Nylon based tooth brush and Ecofriendly toothbrush
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 44 participants
- Where
- 1 siteEgypt
- Study dates
- 18 Nov 2025to 1 May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 8 to 35 months
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Children's age group: Participants must be within the age range of 8 to 11 years.
- This age group is specifically chosen due to the prevalence of mixed dentition, which presents unique challenges and considerations for oral hygiene practices and assessment, and is considered as being a high caries risk profile according to the cariogram parameters. (Tavargeri \& Banerjee, 2021)(Lodha, Saraf, \& Jawdekar, 2023) Adults' age Group: Participants must be within the age range of 18 to 35 years consider as being a high caries risk profile according to the cariogram parameters.
- (AlDhawi et al., 2020; Fageeh et al., 2024) and (Fouad et al., 2022)
Who cannot join
- For the children's age group:
- Lack of parental/guardian consent for participation.
- Currently undergoing orthodontic treatment (fixed or removable appliances).
- Children with special healthcare needs or those who are physically unwell at the time of the study.
- Receipt of professional dental prophylaxis within the previous 3 months.(Tavargeri \& Banerjee, 2021)
- Patient with a cariogenic diet.(Fouad et al., 2022)
Show all 12Show fewer
- For the adult group:
- Currently undergoing orthodontic treatment (fixed or removable appliances).
- Individuals with physical disabilities or any systemic health conditions (e.g.,
- diabetes) that could influence oral health or the ability to perform oral hygiene effectively.
- Receipt of professional dental prophylaxis (e.g., scaling and polishing) within the previous 3 months.(Fageeh et al., 2024)
- Patients with a cariogenic diet. (Fouad et al., 2022)
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effectiveness of Eco-Friendly Toothbrush Compared to Nylon-Based Toothbrush on Cariogram Parameters in Children and Adults: Randomized Controlled Trial
The goal of this clinical trial is to evaluate the effectiveness of an eco-friendly toothbrush compared to a conventional nylon-based toothbrush on cariogram parameters in children and adults. It will also assess the impact of toothbrush type on caries risk factors. The main questions it aims to answer are:
Does the use of an eco-friendly toothbrush improve cariogram parameters compared to a nylon-based toothbrush? Does toothbrush type influence overall caries risk in children and adults?
Read more
Participants will:
- Be randomly assigned to use either an eco-friendly toothbrush or a nylon-based toothbrush
- Use the assigned toothbrush as part of their daily oral hygiene routine for the study period
- Attend scheduled follow-up visits for clinical examination and cariogram assessment
Read the detailed description
This study is a randomized controlled clinical trial designed to compare the effects of an eco-friendly toothbrush and a conventional nylon-based toothbrush on cariogram parameters in children and adults. Eligible participants will be classified by age group and randomly allocated into two intervention groups. At baseline, all participants will undergo clinical examination and caries risk assessment using the Cariogram model. Standardized oral hygiene instructions will be provided to all participants. Participants in each group will use the assigned toothbrush exclusively throughout the study period.
Follow-up assessments will be conducted at predetermined intervals to evaluate changes in cariogram parameters. Compliance with toothbrush use will be monitored during follow-up visits.
The primary outcome is the change in cariogram parameters from baseline to the end of the study period. Secondary outcomes include differences in overall caries risk profile between the two toothbrush groups and between age categories. Data will be analyzed to compare the effects of toothbrush type on cariogram outcomes while accounting for age-related differences
- Conditions
- Caries Assessment, Caries Risk, Oral Health
- Being tested
- Nylon based tooth brush, Ecofriendly toothbrush
- Keywords
- ecofriendly tooth brush, cariogram, nylon tooth brush, children age group, adult age group
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nylon based tooth brushOther
nylon based tooth brush will be used by children and adults age groups
Ecofriendly toothbrushOther
Children and adults group will use ecofriendly tooth brush
| Study group | Role | What they receive |
|---|---|---|
| Children age group | Experimental | children will be randomly assigned to one of the two subgroups accoridng to the type of tooth brushes used Receives: Other: Nylon based tooth brush; Other: Ecofriendly toothbrush |
| Adults age group | Experimental | Adults will be randomly assigned to one of the two subgroups accoridng to the type of tooth brushes used Receives: Other: Nylon based tooth brush; Other: Ecofriendly toothbrush |
What is being measured
The primary outcome is the main question the study is designed to answer.
Caries risk profile determined by cariogram
it determines if the patient is high, moderate and low caries risk after the study
Measured: 6 months follow up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Mar 2026
- Study start18 Nov 2025
- Primary completion18 Apr 2026 (estimated)
- Study completion1 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Caries AssessmentStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 44 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Raneen Ahmed, Suez University
- Investigators
- Raneen Ahmed Gohar, Lecturer, Principal investigator, Lecturer at Department of Operative Dentistry, Faculty of Dentistry, Suez University, P.O. Box:43221, Suez, Egypt
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07467538
- Sponsor's protocol ID
- SUEZMed- IRB-94
- Acronym
- Ecofriendly
- Status last verified
- Mar 2026
- First submitted
- 6 Feb 2026
- Last updated
- 12 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Individual participant data (IPD) will not be shared for the protection of participant confidentiality.
Publications
Fouad, H., Elzoghbi, A., Mosallam, R., & Abouauf, E. (2022). Effectiveness of different preventive regimens on Cariogram parameters of high caries risk patients: A randomized controlled trial. Journal of International Oral Health, 14(2), 128. doi:10.4103/jioh.jioh_316_21
Study at a glance
From the registry record, last updated by the sponsor on 12 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Eco-Friendly Toothbrush Compared to Nylon-Based Toothbrush on Cariogram Parameters in Children and Adults: Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07467538
- Acronym / sponsor ID
- Ecofriendly / SUEZMed- IRB-94
- Conditions
- Caries Assessment, Caries Risk, Oral Health
- Keywords
- ecofriendly tooth brush, cariogram, nylon tooth brush, children age group, adult age group
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 44 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 18 Nov 2025 (actual)
- Primary completion
- 18 Apr 2026 (estimated)
- Study completion
- 1 May 2026 (estimated)
- First posted
- 12 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to evaluate the effectiveness of an eco-friendly toothbrush compared to a conventional nylon-based toothbrush on cariogram parameters in children and adults. It will also assess the impact of toothbrush type on caries risk factors. The main questions it aims to answer are:
Does the use of an eco-friendly toothbrush improve cariogram parameters compared to a nylon-based toothbrush? Does toothbrush type influence overall caries risk in children and adults?
Participants will:
- Be randomly assigned to use either an eco-friendly toothbrush or a nylon-based toothbrush
- Use the assigned toothbrush as part of their daily oral hygiene routine for the study period
- Attend scheduled follow-up visits for clinical examination and cariogram assessment
Detailed description
This study is a randomized controlled clinical trial designed to compare the effects of an eco-friendly toothbrush and a conventional nylon-based toothbrush on cariogram parameters in children and adults. Eligible participants will be classified by age group and randomly allocated into two intervention groups. At baseline, all participants will undergo clinical examination and caries risk assessment using the Cariogram model. Standardized oral hygiene instructions will be provided to all participants. Participants in each group will use the assigned toothbrush exclusively throughout the study period.
Follow-up assessments will be conducted at predetermined intervals to evaluate changes in cariogram parameters. Compliance with toothbrush use will be monitored during follow-up visits.
The primary outcome is the change in cariogram parameters from baseline to the end of the study period. Secondary outcomes include differences in overall caries risk profile between the two toothbrush groups and between age categories. Data will be analyzed to compare the effects of toothbrush type on cariogram outcomes while accounting for age-related differences
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Children age group | Experimental | Other: Nylon based tooth brush, Other: Ecofriendly toothbrushchildren will be randomly assigned to one of the two subgroups accoridng to the type of tooth brushes used |
| Adults age group | Experimental | Other: Nylon based tooth brush, Other: Ecofriendly toothbrushAdults will be randomly assigned to one of the two subgroups accoridng to the type of tooth brushes used |
Who may qualify
- Ages
- 8 to 35 months
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (3 listed)
- Children's age group: Participants must be within the age range of 8 to 11 years.
- This age group is specifically chosen due to the prevalence of mixed dentition, which presents unique challenges and considerations for oral hygiene practices and assessment, and is considered as being a high caries risk profile according to the cariogram parameters. (Tavargeri \& Banerjee, 2021)(Lodha, Saraf, \& Jawdekar, 2023) Adults' age Group: Participants must be within the age range of 18 to 35 years consider as being a high caries risk profile according to the cariogram parameters.
- (AlDhawi et al., 2020; Fageeh et al., 2024) and (Fouad et al., 2022)
Key exclusion criteria (12 listed)
- For the children's age group:
- For the adult group:
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nylon based tooth brushnylon based tooth brush will be used by children and adults age groups | Other | Adults age group, Children age group |
| Ecofriendly toothbrushChildren and adults group will use ecofriendly tooth brush | Other | Adults age group, Children age group |
Primary outcome
Caries risk profile determined by cariogram
Time frame: 6 months follow up
it determines if the patient is high, moderate and low caries risk after the study
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Mar 2026.
- BackgroundFouad, H., Elzoghbi, A., Mosallam, R., & Abouauf, E. (2022). Effectiveness of different preventive regimens on Cariogram parameters of high caries risk patients: A randomized controlled trial. Journal of International Oral Health, 14(2), 128. doi:10.4103/jioh.jioh_316_21
- the ecofriendly toothbrushLink provided by the sponsor.
- Individual participant dataSharing planned: Undecided. Individual participant data (IPD) will not be shared for the protection of participant confidentiality.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Raneen Ahmed Gohar, Lecturer principal investigator
Lecturer at Department of Operative Dentistry, Faculty of Dentistry, Suez University, P.O. Box:43221, Suez, Egypt
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nylon based tooth brush and Ecofriendly toothbrush in people with Caries Assessment and Caries Risk, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 12 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Caries risk profile determined by cariogram (time frame: 6 months follow up). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07467538, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Mar 2026.