Postmenopausal PeriodHIFT-PMNCT07471620
The Effect of High Intensity Functional Exercise Programs on Menopausal Symptoms, Physical Performance, and Dual Task Performance in Postmenopausal Women
A study testing High-intensity functional exercise and moderate to low intensity exercise in people with Postmenopausal Period, run by Uskudar University at 1 site in Turkey (Türkiye).
Trial summary
This study was conducted to examine the effects of exercise programs on the physical and psychosocial health of postmenopausal women. The postmenopausal period is characterized by an increased risk of problems such as decreased muscle strength, balance problems, fatigue, stress, and reduced quality of life due to… Read more about this study
- Who is it for?
- Ages 50 to 65 years, women only
- Conditions the study is for
- Postmenopausal Period
- What is being tested?
- High-intensity functional exercise and moderate to low intensity exercise
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 29 Nov 2025to 1 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 65 years
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- The participant must have had at least 12 months pass since their last menstrual period.
- The participant must be between 50-65 years of age.
- The participant must be able to walk independently.
- The participant must have sufficient cognitive function.
Who cannot join
- Neurological disorders
- Active vestibular disorder
- Lower extremity surgery or serious orthopedic injury
- Severe arthritis and pain affecting walking
- Use of sedative psychoactive drugs
- Cognitive impairment
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of High-Intensity Functional Exercise Programs on Menopausal Symptoms, Physical Performance, and Dual-Task Performance in Postmenopausal Women
This study was conducted to examine the effects of exercise programs on the physical and psychosocial health of postmenopausal women. The postmenopausal period is characterized by an increased risk of problems such as decreased muscle strength, balance problems, fatigue, stress, and reduced quality of life due to hormonal changes. Therefore, appropriate exercise approaches are crucial during this period.
The study evaluated the effects of regular and planned exercise programs on the physical functions and overall well-being of postmenopausal women.
The study also addressed structured exercise approaches such as high-intensity functional training (HIFT). HIFT consists of short but intense exercises similar to daily activities. However, such exercises should be planned and monitored by healthcare professionals according to the individual's age and health status.
Read the detailed description
Menopause is a natural process that occurs with the end of a woman's reproductive years, and due to hormonal changes, many physiological, psychological, and functional symptoms are observed. During this period, decreased estrogen levels are associated with sleep disturbances, vasomotor symptoms, fatigue, depressive mood, musculoskeletal complaints, and a significant decrease in quality of life. Exercise is one of the most effective, low-cost, and safe methods to alleviate menopausal symptoms and improve functionality. However, studies investigating the effects of HIFT on menopausal symptoms, physical performance, and dual-task performance in postmenopausal women are quite limited.
- Conditions
- Postmenopausal Period
- Being tested
- High-intensity functional exercise, moderate to low intensity exercise
- Keywords
- dual task, postmenopause, high intensity functional training
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
High-intensity functional exerciseBehavioural
Participants in the exercise group followed a high-intensity functional exercise program designed to improve physical function, menopausal symptoms, and dual-task performance during the postmenopausal period.
moderate to low intensity exerciseBehavioural
Control group participants performed moderate or low-intensity exercise.
| Study group | Role | What they receive |
|---|---|---|
| High Intensity Functional Training Group | Experimental | group that performs high-intensity functional exercises Receives: Behavioral: High-intensity functional exercise |
| Control Group | Active comparator | moderate to low intensity exercise Receives: Behavioral: moderate to low intensity exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
short physical performance battery
Short Physical Performance Battery (SPPB) is a brief and standardized test battery used to assess lower-extremity physical performance, particularly in older adults. The test evaluates three main functional components: balance, gait speed, and chair-stand performance.
Each subtest is scored between 0 and 4 points, resulting in a total score ranging from 0 to 12. Higher scores indicate better physical performance. The SPPB is widely used in clinical research and geriatric assessments to determine functional capacity, risk of falls, and level of physical independence.
Measured: 8 weeks
Secondary outcomes (1)
Dual task performance
Dual-task performance refers to an individual's ability to perform two tasks simultaneously. It is commonly assessed by combining a motor task (such as walking) with a cognitive task (such as counting or word generation) at the same time. This assessment is widely used to examine cognitive-motor interaction, balance control, and fall risk, particularly in older adults.
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Mar 2026
- Study start29 Nov 2025
- Primary completion1 Feb 2026
- Study completion1 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Postmenopausal PeriodStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- A two-group parallel intervention model was applied, with exercise and control groups monitored simultaneously.
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Uskudar University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Filiz Eyüboğlu, PhD, Study director, Uskudar UniversityNazlı H Gözütok, Principal investigator, Uskudar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07471620
- Sponsor's protocol ID
- 61351342/020-1603
- Acronym
- HIFT-PM
- Status last verified
- Mar 2026
- First submitted
- 26 Feb 2026
- Last updated
- 13 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Feito Y, Heinrich KM, Butcher SJ, Poston WSC. High-Intensity Functional Training (HIFT): Definition and Research Implications for Improved Fitness. Sports (Basel). 2018 Aug 7;6(3):76. doi: 10.3390/sports6030076.
PubMed 30087252Crawford DA, Drake NB, Carper MJ, DeBlauw J, Heinrich KM. Are Changes in Physical Work Capacity Induced by High-Intensity Functional Training Related to Changes in Associated Physiologic Measures? Sports (Basel). 2018 Mar 27;6(2):26. doi: 10.3390/sports6020026.
PubMed 29910330Gozutok NH, Eyuboglu F. Effects of a high-intensity functional exercise program on menopausal symptoms, physical performance, and dual-task performance in postmenopausal women: a randomized controlled trial. BMC Womens Health. 2026 Jun 1;26(1):393. doi: 10.1186/s12905-026-04572-2.
PubMed 42226147
Study at a glance
From the registry record, last updated by the sponsor on 13 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of High-Intensity Functional Exercise Programs on Menopausal Symptoms, Physical Performance, and Dual-Task Performance in Postmenopausal Women
- ClinicalTrials.gov ID
- NCT07471620
- Acronym / sponsor ID
- HIFT-PM / 61351342/020-1603
- Conditions
- Postmenopausal Period
- Keywords
- dual task, postmenopause, high intensity functional training
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Uskudar UniversityUniversity, hospital or other
- Study start
- 29 Nov 2025 (actual)
- Primary completion
- 1 Feb 2026 (actual)
- Study completion
- 1 Feb 2026 (actual)
- First posted
- 13 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study was conducted to examine the effects of exercise programs on the physical and psychosocial health of postmenopausal women. The postmenopausal period is characterized by an increased risk of problems such as decreased muscle strength, balance problems, fatigue, stress, and reduced quality of life due to hormonal changes. Therefore, appropriate exercise approaches are crucial during this period.
The study evaluated the effects of regular and planned exercise programs on the physical functions and overall well-being of postmenopausal women.
The study also addressed structured exercise approaches such as high-intensity functional training (HIFT). HIFT consists of short but intense exercises similar to daily activities. However, such exercises should be planned and monitored by healthcare professionals according to the individual's age and health status.
Detailed description
Menopause is a natural process that occurs with the end of a woman's reproductive years, and due to hormonal changes, many physiological, psychological, and functional symptoms are observed. During this period, decreased estrogen levels are associated with sleep disturbances, vasomotor symptoms, fatigue, depressive mood, musculoskeletal complaints, and a significant decrease in quality of life. Exercise is one of the most effective, low-cost, and safe methods to alleviate menopausal symptoms and improve functionality. However, studies investigating the effects of HIFT on menopausal symptoms, physical performance, and dual-task performance in postmenopausal women are quite limited.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- A two-group parallel intervention model was applied, with exercise and control groups monitored simultaneously.
| Arm | Type | Receives |
|---|---|---|
| High Intensity Functional Training Group | Experimental | Behavioral: High-intensity functional exercisegroup that performs high-intensity functional exercises |
| Control Group | Active comparator | Behavioral: moderate to low intensity exercisemoderate to low intensity exercise |
Who may qualify
- Ages
- 50 to 65 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- The participant must have had at least 12 months pass since their last menstrual period.
- The participant must be between 50-65 years of age.
- The participant must be able to walk independently.
- The participant must have sufficient cognitive function.
Key exclusion criteria (6 listed)
- Neurological disorders
- Active vestibular disorder
- Lower extremity surgery or serious orthopedic injury
- Severe arthritis and pain affecting walking
- Use of sedative psychoactive drugs
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| High-intensity functional exerciseParticipants in the exercise group followed a high-intensity functional exercise program designed to improve physical function, menopausal symptoms, and dual-task performance during the postmenopausal period. | Behavioural | High Intensity Functional Training Group |
| moderate to low intensity exerciseControl group participants performed moderate or low-intensity exercise. | Behavioural | Control Group |
Primary outcome
short physical performance battery
Time frame: 8 weeks
Short Physical Performance Battery (SPPB) is a brief and standardized test battery used to assess lower-extremity physical performance, particularly in older adults. The test evaluates three main functional components: balance, gait speed, and chair-stand performance. Each subtest is scored between 0 and 4 points, resulting in a total score ranging from 0 to 12. Higher scores indicate better physical performance. The SPPB is widely used in clinical research and geriatric assessments to determine functional capacity, risk of falls, and level of physical independence.
1 secondary outcome
Dual task performance
Time frame: 8 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Mar 2026.
- Background: PubMed 30087252Feito Y, Heinrich KM, Butcher SJ, Poston WSC. High-Intensity Functional Training (HIFT): Definition and Research Implications for Improved Fitness. Sports (Basel). 2018 Aug 7;6(3):76. doi: 10.3390/sports6030076.
- Background: PubMed 29910330Crawford DA, Drake NB, Carper MJ, DeBlauw J, Heinrich KM. Are Changes in Physical Work Capacity Induced by High-Intensity Functional Training Related to Changes in Associated Physiologic Measures? Sports (Basel). 2018 Mar 27;6(2):26. doi: 10.3390/sports6020026.
- Derived from this study: PubMed 42226147Gozutok NH, Eyuboglu F. Effects of a high-intensity functional exercise program on menopausal symptoms, physical performance, and dual-task performance in postmenopausal women: a randomized controlled trial. BMC Womens Health. 2026 Jun 1;26(1):393. doi: 10.1186/s12905-026-04572-2.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Filiz Eyüboğlu, PhD study director
Uskudar University
Nazlı H Gözütok principal investigator
Uskudar University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing High-intensity functional exercise and moderate to low intensity exercise in people with Postmenopausal Period, run by Uskudar University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
short physical performance battery (time frame: 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07471620, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Mar 2026.