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Alcohol Use DisorderIDEAS-AUDNCT07475988

Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in Tanzania

A study testing IDEAS-AUD in people with Alcohol Use Disorder and Suicide Prevention, run by Duke University.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts
Official record
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Trial summary

Together, alcohol use and suicide account for approximately 4 million deaths per year, with a considerable burden on low and middle-income countries. Tanzania is among the world's most underserved nations for mental health treatment, with very little capacity to treat suicidality or alcohol use disorders. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Alcohol Use Disorder, Suicide Prevention
What is being tested?
IDEAS-AUD
Could I receive a placebo?
No, everyone receives an active treatment
How many people
30 participants
Where
No sites listed yet
Study dates
Aug 2027to Mar 2029
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • 18 years of age or older
  • screen positive for alcohol use disorder (AUDIT >=8)
  • have had suicidal thinking (C-SSRS item indicating "actual thoughts of suicide") in last 30 days
  • clinically sober
  • medically stable
  • have the physical and cognitive capacity to provide consent and complete study procedures
  • able to communicate in Swahili or English

Who cannot join

  • prisoners
  • decline or unable to complete informed consent

Trial locations and contacts

No sites are listed yet. Contact the study team or a site near you to ask about taking part.

Brandon Knettel, PhD contact

9196601218

brandon.knettel@duke.edu

About this study

Official title: Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in Tanzania: IDEAS-AUD

Together, alcohol use and suicide account for approximately 4 million deaths per year, with a considerable burden on low and middle-income countries. Tanzania is among the world's most underserved nations for mental health treatment, with very little capacity to treat suicidality or alcohol use disorders. In this study, the researchers will adapt an evidence-based intervention for suicide prevention to address the unique needs of people with alcohol use disorders in Tanzania, and rigorously pilot test the intervention to assess its feasibility and acceptability in a Tanzanian emergency department.

Read the detailed description

Globally, alcohol use disorders (AUD) cause 3.3 million deaths each year and account for nearly 100 million disability-adjusted life years (DALYs). Alcohol use is also one of the most prominent risk factors for death by suicide, as people with AUD have a lifetime risk of suicide more than 7 times higher than the general population. In preliminary studies at Kilimanjaro Christian Medical Centre (KCMC) in Tanzania, 7% of patients with AUD met criteria for comorbid depression, 7% were experiencing suicidal thoughts or behavior, and nearly half reported challenges in social support. Unfortunately, Tanzania is also among the most underserved nations in the world for mental health treatment, with fewer than 1 psychologist or psychiatrist per 1 million people and very little capacity to intervene for suicide risk or AUD. Given this shortage in treatment, there is a critical need for innovative, resource-efficient treatments for suicide prevention among people with AUD. In Tanzania, 91% of the population owns a cellular phone and nearly 50% use mobile internet, yet telehealth interventions have been largely unexplored, representing a major missed opportunity for delivering evidence-based interventions. By adapting an evidence-based Motivational Interviewing intervention, MI-SafeCope, the team developed IDEAS for Hope, a telehealth intervention for suicide prevention in HIV care in Tanzania. In the current grant, the researchers propose to revisit this process by adapting MI-SafeCope, with lessons learned from the HIV study, to reduce suicide risk among people with AUD who are presenting for care in the KCMC Emergency Department (ED). The resulting intervention, IDEAS-AUD, will address suicide risk with a four-pillared approach: reducing alcohol-related harm, building social support, enhancing emotional health, and addressing social determinants of health. The pillars are integrated with Motivational Interviewing-enhanced safety planning and referral for local psychiatric care as appropriate. The long-term goal is to create evidence-based, accessible, and cost-effective treatments for mental health and substance use treatment in low-resource settings. The objectives of this proposal are to: 1) adapt IDEAS-AUD for the AUD population in Kilimanjaro, Tanzania; 2) rigorously evaluate the acceptability and feasibility of IDEAS-AUD; and 3) develop the intervention package, along with a trialability evaluation, for a future implementation evaluation and clinical trial. In Aim 1 of the current study, the researchers will identify drivers of suicide risk and desired intervention characteristics to prevent suicide in the AUD population at KCMC. In Aim 2, the study team will adapt an evidence-based suicide prevention intervention to existing AUD care, guided by a community coalition. In Aim 3, the investigators will pilot test the telehealth intervention to assess its feasibility and acceptability for reducing suicide risk in the KCMC AUD population. By the end of this proposed project, the researchers will have a framework-guided, culturally- and resource-adapted, piloted protocol for IDEAS-AUD, including screening tools, programmatic, and implementation components.

Being tested
IDEAS-AUD
Keywords
Telehealth, Nurse-delivered interventions, Stigma reduction, Care engagement, Suicide prevention, Health behavior, Alcohol use disorder, Harm reduction
Medical subject headings
Alcoholism, Suicide Prevention, Health Behavior, Harm Reduction

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • IDEAS-AUDBehavioural

    Telehealth-delivered counseling to reduce suicide risk among people with Alcohol Use Disorder (AUD) who are presenting for care in the KCMC Emergency Department (ED).

Study groups in NCT07475988
Study groupRoleWhat they receive
IDEAS-AUDExperimental3 sessions of telehealth-delivered counseling
Receives: Behavioral: IDEAS-AUD

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Acceptability of intervention

    Acceptability of Intervention Measure (AIM). Four items scored from 1-Completely disagree to 5-Completely agree. Scores are summed for a total score of 4 to 20, with higher scores indicating greater acceptability.

    Measured: 3 months

  2. Enrollment feasibility as measured by the percentage of ED patients with documented screening for study eligibility

    Measured: up to 1 year

  3. Enrollment feasibility as measured by the number of eligible participants who declined enrollment

    Measured: up to 1 year

  4. Enrollment feasibility as measured by the time needed to enroll 30 eligible participants

    Measured: up to 1 year

  5. Retention feasibility as measured by the number of participants retained for follow-up

    Measured: session 2 (2 weeks), session 3 (4 weeks), and 3 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted17 Mar 2026
  2. Study startAug 2027 (estimated)
  3. Primary completionMar 2029 (estimated)
  4. Study completionMar 2029 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Health services research
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrolment
30 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07475988
Sponsor's protocol ID
Pro00118645
Acronym
IDEAS-AUD
Status last verified
Mar 2026
First submitted
12 Mar 2026
Last updated
17 Mar 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes

Questions about this trial

What is this clinical trial studying?

A study testing IDEAS-AUD in people with Alcohol Use Disorder and Suicide Prevention, run by Duke University.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 17 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Brandon Knettel, PhD (9196601218, brandon.knettel@duke.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Acceptability of intervention (time frame: 3 months). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Mar 2026.

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