Sacroiliac DysfunctionNCT07477717
COMBINATION OF LATISSIMUS DORSI AND GLUTEAL STRENGTHENING IN SACROILIAC DYSFUNCTION
A study testing Gluteal strengthening exercise program and Gluteal strengthening combined with LD strengthening exercise program in people with Sacroiliac Dysfunction, run by Cairo University at 1 site in Egypt.
Trial summary
The current study will try to answer the following research question: In adults with sacroiliac joint dysfunction, what is the effect of combination LD strengthening exercises with gluteal strengthening exercises compared with gluteal strengthening exercises alone on the primary outcomes of this study (pain intensity… Read more about this study
- Who is it for?
- Ages 35 to 55 years
- Conditions the study is for
- Sacroiliac Dysfunction
- What is being tested?
- Gluteal strengthening exercise program and Gluteal strengthening combined with LD strengthening exercise program
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Apr 2026to 30 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 55 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patient with clinical diagnosis of low back pain because of SIJD.
- Age between 35-55 years old.
- Numeric pain rating scale (NPRS) score of less than 8
- moderate disability score ranging from 5-14 on the Arabic version of Roland-Arabic Disability Questionnaire (ArRMDQ).
- Patients with unilateral chronic pain for more than 3 months below L5 overlap the posterior aspect of the SIJ around PSIS.
- Patients with gluteal pain with or without groin pain, with or without lower extremity pain that are not compatible with the lumbar nerve roots dermatome.
- ≥4 in the diagnostic scoring system.
- Two out of 4 positive tests in a cluster of Laslett.
Who cannot join
- Patients with any previous fractures or surgery in the lumbosacral or pelvic region before the study.
- Pregnancy and lactation during study.
- Radicular pain or radiculopathy.
- Spinal pathology.
- Participation in physiotherapy sessions within 6 months before enrollment in the study.
- Injection of corticosteroids or anaesthetics in the SIJ during the previous month.
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- Sacroiliac infection or sacroiliitis.
- Neurological signs of spinal stenosis.
- Uncontrolled hyper-tension.
- Treatment, including non-steroidal anti-inflammatories and painkillers, during the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
Outpatient clinic of faculty of physical therapy, Cairo University
Cairo
About this study
Official title: COMBINATION OF LATISSIMUS DORSI AND GLUTEAL STRENGTHENING ON CLINICAL SYMPTOMS AND PELVIC ALIGNMENT IN SACROILIAC DYSFUNCTION
The current study will try to answer the following research question:
In adults with sacroiliac joint dysfunction, what is the effect of combination LD strengthening exercises with gluteal strengthening exercises compared with gluteal strengthening exercises alone on the primary outcomes of this study (pain intensity during pressure on posterior superior iliac spine [PSIS] and neuropathic pain severity) and the secondary outcomes (disability, pelvic inclination, pelvic torsion, sacral inclination, GMax and LD strength)?
Read more
Participants will be devided equally into two groups:
- Group A (Control group): will receive a gluteal strengthening exercise program.
- Group B (Intervention group): will receive the same gluteal strengthening exercise program as group A, in addition to the LD strengthening exercise program.
Read the detailed description
Sacroiliac joint dysfunction (SIJD) is an underappreciated source of low back or buttock pain. It accounts for up to 40% of nonspecific low back pain cases. The prevalence of SIJD was 30% in students with LBP. The impact of SIJD on quality of life is comparable to that observed with osteoarthritis and spinal stenosis and is higher than many cardiovascular-related medical conditions.
One of the main risk factors associated with SIJD is inadequate force closure needed to stabilize the joint during movement, altered muscle coordination, and reduced muscle strength. The primary muscles responsible for force closure are the gluteus maximus (GMax) and latissimus dorsi (LD), as tension is transmitted from one side of the trunk to the other through their connection into the superficial layer of the thoracolumbar fascia (TLF).
GMax muscles showed a trend of reduced resting thickness of the muscles on the side of SJD when compared with the contralateral joint, as well as against the matched healthy individuals, while muscle thickness of LD reduced on the contralateral side as compared to the ipsilateral as well as against the matched healthy controls. On the other hand, the amplitude values of LD of the LBP group were significantly higher than those of the control group on both sides. But GMax amplitude was significantly lower than that of the control group on both sides.
To the best of the authors' knowledge, although both the latissimus dorsi (LD) and gluteal muscles play a crucial role in maintaining sacroiliac joint (SIJ) stability, limited studies compared the effect of incorporating LD activation exercises into gluteal strengthening programs for patients with sacroiliac joint dysfunction (SIJD).
This study will evaluate and compare between effect of adding LD activation exercises to the gluteal strengthening exercises and gluteal strengthening alone on neuropathic pain severity, pain intensity during pressure on PSIS, disability, pelvic inclination, pelvic torsion, and sacral inclination, GMax and LD strength.
- Conditions
- Sacroiliac Dysfunction
- Being tested
- Gluteal strengthening exercise program, Gluteal strengthening combined with LD strengthening exercise program
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gluteal strengthening exercise programOther
Retro Step-Up Unilateral Wall Squat Wall Press Exercise Prone Hip Extension The treatment duration will be 6 weeks at a frequency of 3 supervised sessions/week (18 sessions total).
Gluteal strengthening combined with LD strengthening exercise programOther
Retro Step-Up Unilateral Wall Squat Wall Press Exercise Prone Hip Extension Conventional shoulder extension in the prone position Downward bar pulling in the seated position (LPD) following expert instruction Pull-down exercises from standing position Inverted row body weight exercises with a supinated grip and double-leg WB Modified curl-up Ipsilateral upper trunk bending The treatment duration will be 6 weeks at a frequency of 3 supervised sessions/week (18 sessions total).
| Study group | Role | What they receive |
|---|---|---|
| Gluteal strengthening exercise program | Active comparator | Retro Step-Up Unilateral Wall Squat Wall Press Exercise Prone Hip Extension Receives: Other: Gluteal strengthening exercise program |
| Gluteal strengthening combined with LD strengthening exercise program | Experimental | Retro Step-Up Unilateral Wall Squat Wall Press Exercise Prone Hip Extension Conventional shoulder extension in the prone position Downward bar pulling in the seated position (LPD) following expert instruction Pull-down exercises from standing position Inverted row body weight exercises with a supinated grip and double-leg WB Modified curl-up Ipsilateral upper trunk bending Receives: Other: Gluteal strengthening combined with LD strengthening exercise program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain intensity using the Arabic version of the numeric pain rating scale (Ar-NPRS) during PSIS pressure
Ar- NPRS comprises an 11-point -horizontal scale‖ of 0-10 in Arabic numerals anchored by the two ends, the left (0 indicating no pain at all) and right (10) indicating the worst pain ever. Mild pain ranges from 1-3, moderate pain 4-6 and severe pain 7-10. The patients can indicate the number that describes their pain level closely.
Measured: week 7
Secondary outcomes (1)
Disability using the Arabic Roland-Morris disability questionnaire (ArRMDQ)
The Arabic version of Roland-Morris Disability Questionnaire (ArRMDQ) consists of 24 items ranging from 0 to 24. Statements were chosen to cover multiple aspects of daily living, and the phrase -because of my back‖ was added to each statement to specify that the limitation described was due to back problems
Measured: week 7
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Mar 2026
- Study start1 Apr 2026 (estimated)
- Primary completion30 Aug 2026 (estimated)
- Study completion30 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Sacroiliac DysfunctionStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Shefaa Abdel-Aziz Mohamed Elsayed Shuaib, Cairo University
- Investigators
- Shefaa AA Shuaib, MSc, Principal investigator, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07477717
- Sponsor's protocol ID
- LD strengthening in SID
- Status last verified
- Mar 2026
- First submitted
- 13 Mar 2026
- Last updated
- 17 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- COMBINATION OF LATISSIMUS DORSI AND GLUTEAL STRENGTHENING ON CLINICAL SYMPTOMS AND PELVIC ALIGNMENT IN SACROILIAC DYSFUNCTION
- ClinicalTrials.gov ID
- NCT07477717
- Acronym / sponsor ID
- LD strengthening in SID
- Conditions
- Sacroiliac Dysfunction
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Apr 2026 (estimated)
- Primary completion
- 30 Aug 2026 (estimated)
- Study completion
- 30 Nov 2026 (estimated)
- First posted
- 17 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The current study will try to answer the following research question:
In adults with sacroiliac joint dysfunction, what is the effect of combination LD strengthening exercises with gluteal strengthening exercises compared with gluteal strengthening exercises alone on the primary outcomes of this study (pain intensity during pressure on posterior superior iliac spine [PSIS] and neuropathic pain severity) and the secondary outcomes (disability, pelvic inclination, pelvic torsion, sacral inclination, GMax and LD strength)?
Participants will be devided equally into two groups:
- Group A (Control group): will receive a gluteal strengthening exercise program.
- Group B (Intervention group): will receive the same gluteal strengthening exercise program as group A, in addition to the LD strengthening exercise program.
Detailed description
Sacroiliac joint dysfunction (SIJD) is an underappreciated source of low back or buttock pain. It accounts for up to 40% of nonspecific low back pain cases. The prevalence of SIJD was 30% in students with LBP. The impact of SIJD on quality of life is comparable to that observed with osteoarthritis and spinal stenosis and is higher than many cardiovascular-related medical conditions.
One of the main risk factors associated with SIJD is inadequate force closure needed to stabilize the joint during movement, altered muscle coordination, and reduced muscle strength. The primary muscles responsible for force closure are the gluteus maximus (GMax) and latissimus dorsi (LD), as tension is transmitted from one side of the trunk to the other through their connection into the superficial layer of the thoracolumbar fascia (TLF).
GMax muscles showed a trend of reduced resting thickness of the muscles on the side of SJD when compared with the contralateral joint, as well as against the matched healthy individuals, while muscle thickness of LD reduced on the contralateral side as compared to the ipsilateral as well as against the matched healthy controls. On the other hand, the amplitude values of LD of the LBP group were significantly higher than those of the control group on both sides. But GMax amplitude was significantly lower than that of the control group on both sides.
To the best of the authors' knowledge, although both the latissimus dorsi (LD) and gluteal muscles play a crucial role in maintaining sacroiliac joint (SIJ) stability, limited studies compared the effect of incorporating LD activation exercises into gluteal strengthening programs for patients with sacroiliac joint dysfunction (SIJD).
This study will evaluate and compare between effect of adding LD activation exercises to the gluteal strengthening exercises and gluteal strengthening alone on neuropathic pain severity, pain intensity during pressure on PSIS, disability, pelvic inclination, pelvic torsion, and sacral inclination, GMax and LD strength.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Gluteal strengthening exercise program | Active comparator | Other: Gluteal strengthening exercise programRetro Step-Up Unilateral Wall Squat Wall Press Exercise Prone Hip Extension |
| Gluteal strengthening combined with LD strengthening exercise program | Experimental | Other: Gluteal strengthening combined with LD strengthening exercise programRetro Step-Up Unilateral Wall Squat Wall Press Exercise Prone Hip Extension Conventional shoulder extension in the prone position Downward bar pulling in the seated position (LPD) following expert instruction Pull-down exercises from standing position Inverted row body weight exercises with a supinated grip and double-leg WB Modified curl-up Ipsilateral upper trunk bending |
Who may qualify
- Ages
- 35 to 55 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (8 listed)
- Patient with clinical diagnosis of low back pain because of SIJD.
- Age between 35-55 years old.
- Numeric pain rating scale (NPRS) score of less than 8
- moderate disability score ranging from 5-14 on the Arabic version of Roland-Arabic Disability Questionnaire (ArRMDQ).
- Patients with unilateral chronic pain for more than 3 months below L5 overlap the posterior aspect of the SIJ around PSIS.
Key exclusion criteria (10 listed)
- Patients with any previous fractures or surgery in the lumbosacral or pelvic region before the study.
- Pregnancy and lactation during study.
- Radicular pain or radiculopathy.
- Spinal pathology.
- Participation in physiotherapy sessions within 6 months before enrollment in the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gluteal strengthening exercise programRetro Step-Up Unilateral Wall Squat Wall Press Exercise Prone Hip Extension The treatment duration will be 6 weeks at a frequency of 3 supervised sessions/week (18 sessions total). | Other | Gluteal strengthening exercise program |
| Gluteal strengthening combined with LD strengthening exercise programRetro Step-Up Unilateral Wall Squat Wall Press Exercise Prone Hip Extension Conventional shoulder extension in the prone position Downward bar pulling in the seated position (LPD) following expert instruction Pull-down exercises from standing position Inverted row body weight exercises with a supinated grip and double-leg WB Modified curl-up Ipsilateral upper trunk bending The treatment duration will be 6 weeks at a frequency of 3 supervised sessions/week (18 sessions total). | Other | Gluteal strengthening combined with LD strengthening exercise program |
Primary outcome
Pain intensity using the Arabic version of the numeric pain rating scale (Ar-NPRS) during PSIS pressure
Time frame: week 7
Ar- NPRS comprises an 11-point -horizontal scale‖ of 0-10 in Arabic numerals anchored by the two ends, the left (0 indicating no pain at all) and right (10) indicating the worst pain ever. Mild pain ranges from 1-3, moderate pain 4-6 and severe pain 7-10. The patients can indicate the number that describes their pain level closely.
1 secondary outcome
Disability using the Arabic Roland-Morris disability questionnaire (ArRMDQ)
Time frame: week 7
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Shefaa AA Shuaib, MSc principal investigator
Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gluteal strengthening exercise program and Gluteal strengthening combined with LD strengthening exercise program in people with Sacroiliac Dysfunction, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 17 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Shefaa AA Shuaib, MSc (Egypt: 002 01065891770, sshh70535@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain intensity using the Arabic version of the numeric pain rating scale (Ar-NPRS) during PSIS pressure (time frame: week 7). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Mar 2026.