ARFIDDNA_ARFIDNCT07478510
Cognitive Evaluation of Patients With Eating Disorders
An observational study of ARFID and Anorexia Nervosa, run by Istituti Clinici Scientifici Maugeri SpA at 3 sites in Italy.
Trial summary
The goal of this cross - sectional observational study is to improve understanding of the psychological and cognitive characteristics of Feeding and Eating Disorders (FEDs), a group of conditions that represent a growing public health concern due to their significant impact on physical health, emotional well-being… Read more about this study
- Who is it for?
- Ages 14 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- ARFID, Anorexia Nervosa, Bulimia Nervosa
- What is being tested?
- Go/No-go, IAT and WCST
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 84 participants
- Where
- 3 sitesItaly
- Study dates
- 26 Nov 2024to 31 Mar 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 65 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: The study population includes adolescent and adult participants aged between 14 and 65 years, of both sexes, recruited among individuals diagnosed with Feeding and Eating Disorders and healthy control volunteers. The clinical group consists of patients with a diagnosis of Avoidant/Restrictive Food Intake Disorder, anorexia nervosa, or bulimia nervosa, with a Body Mass Index (BMI) lower than 25. Eligible participants must meet the diagnostic criteria for a Feeding and Eating Disorder according to DSM-5-TR and must provide written informed consent to participate in the study. For participants under the age of 18, written consent from parents or legal guardians is required in addition to the minor's assent. A group of healthy control participants will be recruited in order to obtain a sample balanced with the patient group in terms of sex, age, and educational level. The same inclusion and exclusion criteria applied to the patient group will be considered for the control group.
Who may be able to join
- Diagnosis of a Feeding and Eating Disorder (ARFID, anorexia nervosa, or bulimia nervosa);
- Patients of both sexes;
- Age between 14 and 65 years;
- Confirmed diagnosis of a Feeding and Eating Disorder;
- Body Mass Index (BMI) < 25;
- Signed informed consent form for participation in the study.
Who cannot join
- Diagnosis of Bipolar Disorder according to DSM-5-TR criteria;
- Diagnosis of a Schizophrenia Spectrum Disorder according to DSM-5-TR criteria;
- Intellectual disability according to DSM-5-TR criteria;
- Presence of brain tumors;
- History of seizure events;
- Presence of other moderate to severe neurological disorders;
- Lack of the patient's consent to voluntary participation in the study;
- Lack of parental or legal guardian consent for participation of a minor in the study.
Trial locations and contacts
3 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Italy3 sites, 3 recruiting
- Recruiting
Istituto Psicologico Italiano s.r.l.s.
Milan, 20124
Pablo Zuglian, PhD, 349 7430677, pablo.zuglian@istitutopsicologico.it
- Recruiting
ASST Fatebenefratelli Sacco
Milan, 20157
Lorenzo Casati, MD Psychiatrist, +390239042904, lorenzo.casati@asst-fbf-sacco.it
- Recruiting
IUSS Pavia - Istituto Universitario di Studi Superiori
Pavia, PV, 27100
Giulia Camilla Mattavelli, giulia.mattavelli@iusspavia.it
About this study
Official title: Neuro-cognitive Profiles of Patients With Nutritional and Eating Disorders
The goal of this cross - sectional observational study is to improve understanding of the psychological and cognitive characteristics of Feeding and Eating Disorders (FEDs), a group of conditions that represent a growing public health concern due to their significant impact on physical health, emotional well-being, and everyday functioning. Within this broader diagnostic category, particular attention is given to Avoidant/Restrictive Food Intake Disorder (ARFID), a diagnosis introduced in the DSM-5 and still relatively underexplored compared to other feeding and eating disorders.
Despite its clinical relevance, ARFID remains less well understood in terms of its underlying cognitive and psychological mechanisms. Individuals with ARFID often experience severe food avoidance or restriction that is not driven by weight or shape concerns, but rather by sensory sensitivities, fear of negative consequences of eating, or a lack of interest in food. For this reason, investigating ARFID can offer important insights into the diversity of mechanisms involved in feeding and eating disorders as a whole.
Read more
The study has two main objectives. The first objective is to examine the cognitive profile of individuals with ARFID, with a specific focus on autistic traits and cognitive flexibility, as previous research suggests potential overlaps between ARFID and neurodevelopmental conditions such as Autism Spectrum Disorders. Cognitive flexibility refers to the ability to adapt thoughts and behaviors in response to changing situations, and reduced flexibility may contribute to rigid eating patterns and food avoidance.
The second objective is to explore the role of body representation (how individuals perceive and mentally represent their own body) and inhibitory control (the ability to regulate or suppress automatic responses) in shaping the cognitive and behavioral features of ARFID and other feeding and eating disorders. These processes may help distinguish ARFID from other diagnoses and clarify shared and disorder-specific mechanisms across the FED spectrum.
The study involves adult participants of all genders, including individuals diagnosed with ARFID, anorexia nervosa, and bulimia nervosa, as well as healthy control participants without a history of feeding or eating disorders. This design allows meaningful comparisons between different diagnostic groups and with the general population.
The main questions the study aims to answer are:
Do individuals with ARFID show a distinct cognitive profile, particularly in terms of autistic traits and cognitive flexibility, compared to individuals with other feeding and eating disorders and healthy controls?
How do body representation and inhibitory control contribute to differences in eating-related behaviors across feeding and eating disorders?
Are there differences in brain activity associated with implicit, automatic attitudes toward food in individuals with feeding and eating disorders compared to healthy individuals?
Where comparison groups are included, researchers will compare participants with ARFID, anorexia nervosa, bulimia nervosa, and healthy controls to examine differences in cognitive functioning, psychological characteristics, and neural responses related to food processing.
Participants will be asked to take part in a series of non-invasive and well-established research activities, designed to be accessible and safe. These include:
Completing self-report questionnaires assessing autistic traits, body image perception, and general psychological well-being;
Performing computer-based tasks that assess cognitive flexibility and decision-making;
Completing behavioral tasks designed to measure inhibitory control and automatic associations with food-related stimuli;
- Conditions
- ARFID, Anorexia Nervosa, Bulimia Nervosa, Cognitive Flexibility, Implicit Association Test, Executive Functions
- Being tested
- Go/No-go, IAT, WCST
- Medical subject headings
- Avoidant Restrictive Food Intake Disorder, Anorexia Nervosa, Bulimia Nervosa
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Go/No-goBehavioural
The investigators designed a specific task, base in literature, to evaluate the inibithory response to food stimuli of different types (high calories, low calories, neutral stimuli). The images have been defined by a pilot selection and added to the task designed on Psychopy.
IATBehavioural
The investigators designed a specific task, base in literature, to evaluate the implicit association of body images (overweight, underweight, normalweight) and word to different lables. The body images have been defined by a pilot selection and added to the task designed on Psychopy.
WCSTBehavioural
The Wisconsin Card Sorting Test (WCST) is a neuropsychological assessment of executive function, cognitive flexibility, and abstract reasoning. Participants match stimulus cards based on color, form, or number, adapting to changing, unstated rules based on examiner feedback. It measures the ability to display flexibility in the face of changing schedules of reinforcement, specifically "set-shifting". A participant is given a deck of cards and told to match them, but not how. The examiner says "right" or "wrong," forcing the participant to deduce the rule (color, shape, or number). The rule changes unexpectedly after a certain number of correct matches. It provides scores for categories completed, trials, total errors, and, critically, perseverative errors (continuing to use a previous, invalid rule). The investigators used the 128 cards version.
| Study group | Role | What they receive |
|---|---|---|
| Healthy control | Every participant recieve all the interventions described, each one of them with the specific randomization of subministration. Receives: Behavioral: Go/No-go; Behavioral: IAT; Behavioral: WCST | |
| ARFID | Patients with Avoidant Restrictive Food Intake Disorder. Every participant recieve all the interventions described, each one of them with the specific randomization of subministration. Receives: Behavioral: Go/No-go; Behavioral: IAT; Behavioral: WCST | |
| AN/BN | Patients with a diagnosis of Anorexia Nervosa or Bulimia Nervosa. Every participant recieve all the interventions described, each one of them with the specific randomization of subministration. Receives: Behavioral: Go/No-go; Behavioral: IAT; Behavioral: WCST |
What is being measured
The primary outcome is the main question the study is designed to answer.
What is the cognitive profile of patients with ARFID, with particular reference to autistic traits and cognitive flexibility?
The Autism Spectrum Quotient (AQ) questionnarie has the purpose to evaluate the levels of autistic traits in each participant and permit to understand the differences between the groups.
The scoring of this questionnaire stays in the range 0-50, where 0 is the minimum and associated with less autistic traits and 50 is the maximum outcome possible, explaining elevated autistic traits. Usually, the cut-off is defined as 32, over that score is possible to define the presence of autistic traits.
Measured: Baseline
What is the cognitive profile of patients with ARFID, with particular reference to autistic traits and cognitive flexibility?
The higher the percentage of perseverative errors out of the total errors made on the Wisconsin Card Sorting Test (WCST), the lower the subject's cognitive flexibility. The WCST assesses executive functions, particularly cognitive flexibility, set-shifting ability, and problem-solving strategies. Scoring is typically based on several indices, including number of categories completed, total errors, and perseverative errors, with perseverative errors often expressed as a percentage of total responses.
There is no universally accepted clinical cut-off for WCST performance, as interpretation is usually based on comparison with age-adjusted normative data; however, higher percentages of perseverative errors are generally interpreted as indicating greater executive dysfunction.
The scale starts at 0%, which indicates full cognitive flexibility, and increases accordingly torwards 100%, indicating cognitive rigidity.
Measured: Baseline
Secondary outcomes (4)
What is the role of body representation and inhibitory control capacity in the differential diagnosis between ARFID and other eating disorders, such as Anorexia Nervosa and Bulimia Nervosa?
The assessment of body representation is carried out through the scoring and comparison of participants' scores through the scoring of the Implicit Association Task (IAT), involving implicit associations with body images. Scores on the D-scores emerging as outcomes from the computerized IAT task will be evaluated. The interpretation of scoring has this pattern:
- +0.15 <: no implicit preference
- 0.16 - 0.35: weak preference
- 0.36 - 0.65: moderate preference
- > 0.65: strong preference
The theoretical range of D score is between -2 and 2, but in empirical practise it's moreover between -1,5 and 1,5.
Measured: Baseline
What is the role of body representation and inhibitory control capacity in the differential diagnosis between ARFID and other eating disorders, such as Anorexia Nervosa and Bulimia Nervosa?
The assessment of body representation is carried out through the scoring and comparison of participants' scores on one of the questionnaires included in the project, namely the Body Image Concern Inventory (BICI). It is a 19-item self-report questionnaire assessing dysmorphic concerns related to body image. Each item is rated on a 5-point Likert scale (1 = never, 5 = always). The total score is obtained by summing all items and ranges from 19 to 95, with higher scores indicating greater body image concern. A commonly used cut-off is ≥55 (95th percentile in normative samples), suggesting clinically relevant dysmorphic concern. The scale also includes two subscales: F1 - Dysmorphic Symptoms (preoccupation with perceived appearance flaws) and F2 - Symptom Interference (impact of these concerns on daily functioning).
Measured: Baseline
What is the role of body representation and inhibitory control capacity in the differential diagnosis between ARFID and other eating disorders, such as Anorexia Nervosa and Bulimia Nervosa?
The evaluation of inhibitory control capacity is carried out through a Go/No-go task. The test consists of high and low calorie food pictures or neutral stimuli (circles and squares). This kind of task presents two main outcomes: reaction time (RT) and accuracy.
Reaction time is recorded in milliseconds (ms) and has no theoretical maximum, but in this specific protocol the range of evaluations of answers is between 300 and 1000 ms, where stimuli under 300ms reflects a pattern of impulsivity and stimuli over 1000 ms of answers are not registred by the task, defining low reactivity.
Accuracy represents the percentage of correct responses (0-100%). The task does not have validated clinical cut-offs, as it is a continuous experimental measure rather than a diagnostic test. Normative interpretation is usually based on sample comparison or statistical ranges (e.g., mean ± 2 SD) rather than fixed thresholds.
Measured: Baseline
What is the role of body representation and inhibitory control capacity in the differential diagnosis between ARFID and other eating disorders, such as Anorexia Nervosa and Bulimia Nervosa?
The Eating Disorder Inventory-3 (EDI-3) is a self-report questionnaire used to assess psychological and behavioral traits associated with eating disorders and is commonly used in the differential diagnosis, particularly to evaluate body image disturbance. It includes 91 items rated on a 6-point Likert scale that are recoded from 0 to 4 and summed to produce 12 primary scales.
The instrument does not provide a single total score and cut-offs are not strictly diagnostic, although T-scores ≥60-65 are generally considered clinically elevated and ≥70 indicates high clinical concern.
Scales most relevant for research on body representation and differential diagnosis are Drive for Thinness, Body Dissatisfaction, and Bulimia, which form the Eating Disorder Risk Composite. Individuals with ARFID are expected to show low scores on these body-image related dimensions compared to those with Anorexia Nervosa or Bulimia Nervosa.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Mar 2026
- Study start26 Nov 2024
- Primary completion31 Mar 2028 (estimated)
- Study completion31 Mar 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ARFIDStudies of the same condition, open and under way.
- More trials run by Istituti Clinici Scientifici Maugeri SpAThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Other
- Enrolment
- 84 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Istituti Clinici Scientifici Maugeri SpA
- Sponsor type
- University, hospital or other
- Collaborators
- Istituto Psicologico Italiano s.r.l.s., ASST Fatebenefratelli Sacco
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07478510
- Sponsor's protocol ID
- 0025652/24
- Acronym
- DNA_ARFID
- Status last verified
- Apr 2026
- First submitted
- 2 Feb 2026
- Last updated
- 16 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Neuro-cognitive Profiles of Patients With Nutritional and Eating Disorders
- ClinicalTrials.gov ID
- NCT07478510
- Acronym / sponsor ID
- DNA_ARFID / 0025652/24
- Conditions
- ARFID, Anorexia Nervosa, Bulimia Nervosa, Cognitive Flexibility, Implicit Association Test, Executive Functions
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 84 participants (estimated)
- Lead sponsor
- Istituti Clinici Scientifici Maugeri SpAUniversity, hospital or other
- Collaborators
- Istituto Psicologico Italiano s.r.l.s., ASST Fatebenefratelli Sacco
- Study start
- 26 Nov 2024 (actual)
- Primary completion
- 31 Mar 2028 (estimated)
- Study completion
- 31 Mar 2028 (estimated)
- First posted
- 17 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this cross - sectional observational study is to improve understanding of the psychological and cognitive characteristics of Feeding and Eating Disorders (FEDs), a group of conditions that represent a growing public health concern due to their significant impact on physical health, emotional well-being, and everyday functioning. Within this broader diagnostic category, particular attention is given to Avoidant/Restrictive Food Intake Disorder (ARFID), a diagnosis introduced in the DSM-5 and still relatively underexplored compared to other feeding and eating disorders.
Despite its clinical relevance, ARFID remains less well understood in terms of its underlying cognitive and psychological mechanisms. Individuals with ARFID often experience severe food avoidance or restriction that is not driven by weight or shape concerns, but rather by sensory sensitivities, fear of negative consequences of eating, or a lack of interest in food. For this reason, investigating ARFID can offer important insights into the diversity of mechanisms involved in feeding and eating disorders as a whole.
The study has two main objectives. The first objective is to examine the cognitive profile of individuals with ARFID, with a specific focus on autistic traits and cognitive flexibility, as previous research suggests potential overlaps between ARFID and neurodevelopmental conditions such as Autism Spectrum Disorders. Cognitive flexibility refers to the ability to adapt thoughts and behaviors in response to changing situations, and reduced flexibility may contribute to rigid eating patterns and food avoidance.
The second objective is to explore the role of body representation (how individuals perceive and mentally represent their own body) and inhibitory control (the ability to regulate or suppress automatic responses) in shaping the cognitive and behavioral features of ARFID and other feeding and eating disorders. These processes may help distinguish ARFID from other diagnoses and clarify shared and disorder-specific mechanisms across the FED spectrum.
The study involves adult participants of all genders, including individuals diagnosed with ARFID, anorexia nervosa, and bulimia nervosa, as well as healthy control participants without a history of feeding or eating disorders. This design allows meaningful comparisons between different diagnostic groups and with the general population.
The main questions the study aims to answer are:
Do individuals with ARFID show a distinct cognitive profile, particularly in terms of autistic traits and cognitive flexibility, compared to individuals with other feeding and eating disorders and healthy controls?
How do body representation and inhibitory control contribute to differences in eating-related behaviors across feeding and eating disorders?
Are there differences in brain activity associated with implicit, automatic attitudes toward food in individuals with feeding and eating disorders compared to healthy individuals?
Where comparison groups are included, researchers will compare participants with ARFID, anorexia nervosa, bulimia nervosa, and healthy controls to examine differences in cognitive functioning, psychological characteristics, and neural responses related to food processing.
Participants will be asked to take part in a series of non-invasive and well-established research activities, designed to be accessible and safe. These include:
Completing self-report questionnaires assessing autistic traits, body image perception, and general psychological well-being;
Performing computer-based tasks that assess cognitive flexibility and decision-making;
Completing behavioral tasks designed to measure inhibitory control and automatic associations with food-related stimuli;
Study design
- Observational model
- Other
- Time perspective
- Other
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Healthy control | – | Behavioral: Go/No-go, Behavioral: IAT, Behavioral: WCSTEvery participant recieve all the interventions described, each one of them with the specific randomization of subministration. |
| ARFID | – | Behavioral: Go/No-go, Behavioral: IAT, Behavioral: WCSTPatients with Avoidant Restrictive Food Intake Disorder. Every participant recieve all the interventions described, each one of them with the specific randomization of subministration. |
| AN/BN | – | Behavioral: Go/No-go, Behavioral: IAT, Behavioral: WCSTPatients with a diagnosis of Anorexia Nervosa or Bulimia Nervosa. Every participant recieve all the interventions described, each one of them with the specific randomization of subministration. |
Who may qualify
- Ages
- 14 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The study population includes adolescent and adult participants aged between 14 and 65 years, of both sexes, recruited among individuals diagnosed with Feeding and Eating Disorders and healthy control volunteers. The clinical group consists of patients with a diagnosis of Avoidant/Restrictive Food Intake Disorder, anorexia nervosa, or bulimia nervosa, with a Body Mass Index (BMI) lower than 25. Eligible participants must meet the diagnostic criteria for a Feeding and Eating Disorder according to DSM-5-TR and must provide written informed consent to participate in the study. For participants under the age of 18, written consent from parents or legal guardians is required in addition to the minor's assent. A group of healthy control participants will be recruited in order to obtain a sample balanced with the patient group in terms of sex, age, and educational level. The same inclusion and exclusion criteria applied to the patient group will be considered for the control group.
Key inclusion criteria (6 listed)
- Diagnosis of a Feeding and Eating Disorder (ARFID, anorexia nervosa, or bulimia nervosa);
- Patients of both sexes;
- Age between 14 and 65 years;
- Confirmed diagnosis of a Feeding and Eating Disorder;
- Body Mass Index (BMI) < 25;
Key exclusion criteria (8 listed)
- Diagnosis of Bipolar Disorder according to DSM-5-TR criteria;
- Diagnosis of a Schizophrenia Spectrum Disorder according to DSM-5-TR criteria;
- Intellectual disability according to DSM-5-TR criteria;
- Presence of brain tumors;
- History of seizure events;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Go/No-goThe investigators designed a specific task, base in literature, to evaluate the inibithory response to food stimuli of different types (high calories, low calories, neutral stimuli). The images have been defined by a pilot selection and added to the task designed on Psychopy. | Behavioural | AN/BN, ARFID, Healthy control |
| IATThe investigators designed a specific task, base in literature, to evaluate the implicit association of body images (overweight, underweight, normalweight) and word to different lables. The body images have been defined by a pilot selection and added to the task designed on Psychopy. | Behavioural | AN/BN, ARFID, Healthy control |
| WCSTThe Wisconsin Card Sorting Test (WCST) is a neuropsychological assessment of executive function, cognitive flexibility, and abstract reasoning. Participants match stimulus cards based on color, form, or number, adapting to changing, unstated rules based on examiner feedback. It measures the ability to display flexibility in the face of changing schedules of reinforcement, specifically "set-shifting". A participant is given a deck of cards and told to match them, but not how. The examiner says "right" or "wrong," forcing the participant to deduce the rule (color, shape, or number). The rule changes unexpectedly after a certain number of correct matches. It provides scores for categories completed, trials, total errors, and, critically, perseverative errors (continuing to use a previous, invalid rule). The investigators used the 128 cards version. | Behavioural | AN/BN, ARFID, Healthy control |
Primary outcome
What is the cognitive profile of patients with ARFID, with particular reference to autistic traits and cognitive flexibility?
Time frame: Baseline
The Autism Spectrum Quotient (AQ) questionnarie has the purpose to evaluate the levels of autistic traits in each participant and permit to understand the differences between the groups. The scoring of this questionnaire stays in the range 0-50, where 0 is the minimum and associated with less autistic traits and 50 is the maximum outcome possible, explaining elevated autistic traits. Usually, the cut-off is defined as 32, over that score is possible to define the presence of autistic traits.
What is the cognitive profile of patients with ARFID, with particular reference to autistic traits and cognitive flexibility?
Time frame: Baseline
The higher the percentage of perseverative errors out of the total errors made on the Wisconsin Card Sorting Test (WCST), the lower the subject's cognitive flexibility. The WCST assesses executive functions, particularly cognitive flexibility, set-shifting ability, and problem-solving strategies. Scoring is typically based on several indices, including number of categories completed, total errors, and perseverative errors, with perseverative errors often expressed as a percentage of total responses. There is no universally accepted clinical cut-off for WCST performance, as interpretation is usually based on comparison with age-adjusted normative data; however, higher percentages of perseverative errors are generally interpreted as indicating greater executive dysfunction. The scale starts at 0%, which indicates full cognitive flexibility, and increases accordingly torwards 100%, indicating cognitive rigidity.
4 secondary outcomes
What is the role of body representation and inhibitory control capacity in the differential diagnosis between ARFID and other eating disorders, such as Anorexia Nervosa and Bulimia Nervosa?
Time frame: Baseline
What is the role of body representation and inhibitory control capacity in the differential diagnosis between ARFID and other eating disorders, such as Anorexia Nervosa and Bulimia Nervosa?
Time frame: Baseline
What is the role of body representation and inhibitory control capacity in the differential diagnosis between ARFID and other eating disorders, such as Anorexia Nervosa and Bulimia Nervosa?
Time frame: Baseline
What is the role of body representation and inhibitory control capacity in the differential diagnosis between ARFID and other eating disorders, such as Anorexia Nervosa and Bulimia Nervosa?
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Apr 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
3 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of ARFID and Anorexia Nervosa, run by Istituti Clinici Scientifici Maugeri SpA at 3 sites in Italy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 16 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 3 sites in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Giulia Mattavelli, Associated prof., researcher (+39 3397893500, giulia.mattavelli@iusspavia.it), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
What is the cognitive profile of patients with ARFID, with particular reference to autistic traits and cognitive flexibility? (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Apr 2026.