Visual CorrectionNCT07481487
Outcomes of Cataract & Refractive Procedures
An observational study of Visual Correction and Refractive Surgery, run by Vision Care Collective Limited at 1 site in United Kingdom.
Trial summary
The primary objective of the database is to retrospectively analyse the visual and refractive outcomes of cataract and refractive procedures in order to continuously assess outcomes and also compare outcomes between the different IOLs, or the different refractive procedures. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Visual Correction, Refractive Surgery, Cataract Surgery
- How many people
- 150 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 15 Apr 2025to 31 Oct 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The population for the database will be existing patients of the clinic. These are patients who presented to the clinic with an interest for a refractive or cataract procedure.
Who may be able to join
- Adult patients who have undergone a refractive procedure
- Adult patients who have undergone a cataract procedure with implantation of an intraocular lens
- Age ≥ 18 years old
- Patient able to consent for their pseudonymised data to be used for research purposes
Who cannot join
- NONE
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United Kingdom1 site, 1 recruiting
- Recruiting
Vision Care Clinic Bristol
Bristol, England, BS8 1BN
Kieren Darcy, BM MRCS (Eng) CertLRS FRCOphth, +44 117 905 7722, contact@visioncareclinic.com
About this study
The primary objective of the database is to retrospectively analyse the visual and refractive outcomes of cataract and refractive procedures in order to continuously assess outcomes and also compare outcomes between the different IOLs, or the different refractive procedures.
- Conditions
- Visual Correction, Refractive Surgery, Cataract Surgery
- Keywords
- cataract, IOL
- Medical subject headings
- Cataract
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Patient of the clinic | The population for the database will be existing patients of the clinic. These are patients who presented to the clinic with an interest for a refractive or cataract procedure. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Post-operative Uncorrected Distance Visual Acuity
Measured: postoperative visit 3-6 months
Post-operative Distance Corrected Visual Acuity
Measured: postoperative visit 3-6 months
Post-operative subjective refraction (Sphere, Cylinder, Axis)
Measured: postoperative visit 3-6 months
Accuracy of post-operative refraction achieved compared to targeted refraction
Measured: postoperative visit 3-6 months
Loss of best-corrected visual acuity compared to preoperatively
Measured: postoperative visit 3-6 months
Occurrence of surgical complications and post-operative complications
Measured: postoperative visit 3-6 months
Post-operative Uncorrected Near Visual Acuity
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Measured: postoperative visit 3-6 months
Post-operative Uncorrected Intermediate Visual Acuity
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Measured: postoperative visit 3-6 months
Post-operative Distance Corrected Near Visual Acuity
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Measured: postoperative visit 3-6 months
Post-operative Distance Corrected Intermediate Visual Acuity
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Measured: postoperative visit 3-6 months
Defocus Curve
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Measured: postoperative visit 3-6 months
Quality of Vision Questionnaire
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Measured: postoperative visit 3-6 months
Contrast Sensitivity
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Measured: postoperative visit 3-6 months
Secondary outcomes (2)
Comparative analysis - Different types of IOLs
Comparative analysis between different types of IOLs might be performed to investigate whether one IOL might offer additional benefits to patients compared to another IOL.
Measured: postoperative visit 3-6 months
Comparative analysis - Refractive procedure
Comparative analysis between different types of refractive procedures might be performed to investigate whether one procedure might offer additional benefits to patients.
Measured: postoperative visit 3-6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Mar 2026
- Study start15 Apr 2025
- Primary completion31 Oct 2026 (estimated)
- Study completion31 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Visual CorrectionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 150 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Vision Care Collective Limited
- Sponsor type
- University, hospital or other
- Collaborators
- Rayner Intraocular Lenses Limited
- Responsible party
- Principal investigator, Kieren Darcy, Vision Care Collective Limited
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07481487
- Sponsor's protocol ID
- DrDarcy_RefractiveDatabase
- Status last verified
- Mar 2026
- First submitted
- 13 Mar 2026
- Last updated
- 18 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Outcomes of Cataract & Refractive Procedures
- ClinicalTrials.gov ID
- NCT07481487
- Acronym / sponsor ID
- DrDarcy_RefractiveDatabase
- Conditions
- Visual Correction, Refractive Surgery, Cataract Surgery
- Keywords
- cataract, IOL
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 150 participants (estimated)
- Lead sponsor
- Vision Care Collective LimitedUniversity, hospital or other
- Collaborators
- Rayner Intraocular Lenses Limited
- Study start
- 15 Apr 2025 (actual)
- Primary completion
- 31 Oct 2026 (estimated)
- Study completion
- 31 Oct 2026 (estimated)
- First posted
- 18 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary objective of the database is to retrospectively analyse the visual and refractive outcomes of cataract and refractive procedures in order to continuously assess outcomes and also compare outcomes between the different IOLs, or the different refractive procedures.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patient of the clinic | – | –The population for the database will be existing patients of the clinic. These are patients who presented to the clinic with an interest for a refractive or cataract procedure. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The population for the database will be existing patients of the clinic. These are patients who presented to the clinic with an interest for a refractive or cataract procedure.
Key inclusion criteria (4 listed)
- Adult patients who have undergone a refractive procedure
- Adult patients who have undergone a cataract procedure with implantation of an intraocular lens
- Age ≥ 18 years old
- Patient able to consent for their pseudonymised data to be used for research purposes
Key exclusion criteria (1 listed)
- NONE
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Post-operative Uncorrected Distance Visual Acuity
Time frame: postoperative visit 3-6 months
Post-operative Distance Corrected Visual Acuity
Time frame: postoperative visit 3-6 months
Post-operative subjective refraction (Sphere, Cylinder, Axis)
Time frame: postoperative visit 3-6 months
Accuracy of post-operative refraction achieved compared to targeted refraction
Time frame: postoperative visit 3-6 months
Loss of best-corrected visual acuity compared to preoperatively
Time frame: postoperative visit 3-6 months
Occurrence of surgical complications and post-operative complications
Time frame: postoperative visit 3-6 months
Post-operative Uncorrected Near Visual Acuity
Time frame: postoperative visit 3-6 months
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Post-operative Uncorrected Intermediate Visual Acuity
Time frame: postoperative visit 3-6 months
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Post-operative Distance Corrected Near Visual Acuity
Time frame: postoperative visit 3-6 months
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Post-operative Distance Corrected Intermediate Visual Acuity
Time frame: postoperative visit 3-6 months
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Defocus Curve
Time frame: postoperative visit 3-6 months
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Quality of Vision Questionnaire
Time frame: postoperative visit 3-6 months
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
Contrast Sensitivity
Time frame: postoperative visit 3-6 months
For intraocular lens offering a visual benefit at near and/or intermediate, such as multifocal IOLs, EDoF (Extended Depth of Focus) IOLs, enhanced monofocal IOLs, and for refractive procedures offering a visual benefit at near and/or intermediate, additional visual outcomes and safety outcomes may be assessed.
2 secondary outcomes
Comparative analysis - Different types of IOLs
Time frame: postoperative visit 3-6 months
Comparative analysis - Refractive procedure
Time frame: postoperative visit 3-6 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Visual Correction and Refractive Surgery, run by Vision Care Collective Limited at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 18 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Kieren Darcy, BM MRCS (Eng) CertLRS FRCOphth (+44 117 905 7722, contact@visioncareclinic.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Post-operative Uncorrected Distance Visual Acuity (time frame: postoperative visit 3-6 months). The study lists 13 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Mar 2026.