Cognitive ImpairmentNCT07484048
A Modified Test of Goal-directed Behaviour: a Feasibility Study
A study testing Five cognitive tasks in people with Cognitive Impairment and Coginitive Assessment, run by Gloucestershire Hospitals NHS Foundation Trust at 2 sites in United Kingdom.
Trial summary
Cognitive assessment plays an important part in decision making in acute neurological settings, partly because difficulties with cognitive skills such as attention, memory and executive functioning (which includes planning and problem-solving) have direct implications for patents' levels of independence and safety… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Cognitive Impairment, Coginitive Assessment
- What is being tested?
- Five cognitive tasks
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 2 sitesUnited Kingdom
- Study dates
- 15 Sep 2025to 1 Apr 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Inclusion criteria for the main (non-neuropsychologist) element include:
- General population. For convenience at this feasibility study stage this will be largely comprised of colleagues working with GHT, above the age of 18, with no upper age limit.
- Have given informed consent having followed the procedure in the protocol
- Have the physical/sensory abilities to undertake the test procedures (e.g. use of both hands, adequate vision)
- Sufficient English language to be able to follow test instructions
Exclusion criteria for the main (non-neuropsychologist) element include:
- Under the age of 18
- Refusal/inability to give informed consent
- Insufficient English language to be able to follow test instructions
- Using cognitive testing as part of their clinical work, or ongoing familiarity with cognitive tests.
- Working directly with the main investigator.
- Presence of a self-reported cognitive difficulty/neurological condition - not because that in itself would be problematic for test administration or for the information generated, but rather to avoid potential distress to participants were they to find the tests administered challenging.
- Presence of any physical/sensory/cognitive difficulty that would confound administration of the tasks, e.g. being partially sighted or having use of only one upper limb
- There are no exclusion criteria based on gender identity, ethnicity or handedness.
- There are no exclusion criteria relating to medication.
Inclusion criteria for the PPI (neuropsychologist) element include:
- clinical psychologists in GHT who have or have had a role that involves the administration of cognitive tests
- Have given informed consent having followed the procedure in the protocol
- Have the physical/sensory abilities to undertake the test procedures (e.g. use of both hands, adequate vision)
- Sufficient English language to be able to follow test instructions
Exclusion criteria for the PPI (neuropsychologist) element include:
- Under the age of 18
- Refusal/inability to give informed consent
- Insufficient English language to be able to follow test instructions
- Presence of a self-reported cognitive difficulty/neurological condition - not because that in itself would be problematic for test administration or for the information generated, but rather to avoid potential distress to participants were they to find the tests administered challenging.
- Presence of any physical/sensory/cognitive difficulty that would confound administration of the tasks, e.g. being partially sighted or having use of only one upper limb
- There are no exclusion criteria based on gender identity, ethnicity or handedness.
- There are no exclusion criteria relating to medication.
Trial locations and contacts
2 sites in 1 country.
United Kingdom2 sites
Cheltenham General Hospital
Cheltenham, Gloucestershire, GL53 7AN
Gloucestershire Royal Hospital
Gloucester, Gloucestershire, GL1 3NN
About this study
Official title: Feasibility Study for Development of a Modified Bedside Test of Goal-directed Behaviour
Cognitive assessment plays an important part in decision making in acute neurological settings, partly because difficulties with cognitive skills such as attention, memory and executive functioning (which includes planning and problem-solving) have direct implications for patents' levels of independence and safety upon discharge.
A bedside cognitive task that could shed light upon a patient's ability to demonstrate effective goal-directed behaviour (potentially along with other aspects of executive functioning such as cognitive flexibility) would be a useful addition to the existing repertoire of bedside cognitive assessments.
Read more
One such test could be 'Link's Cube'. The Link's Cube Test is impractical for bedside use in an acute ward setting, as it comprises 27 small blocks. The feasibility study aims to preserve the information that is provided by Link's Cube Test (i.e. an indication of the patient's ability to engage in goal-directed behaviour) whilst altering the testing material such that only nine, slightly larger blocks are used.
The objectives for the feasibility study are:
- To identify any practical difficulties in administration of the tests that may not be apparent without trialling them
- To generate information regarding the timing and sequence of overall administration and in particular the proposed modified Link's Cube test
- To obtain feedback from neuropsychologists about ease of administration of the proposed new test and to obtain their views regarding potential benefits
- Conditions
- Cognitive Impairment, Coginitive Assessment
- Being tested
- Five cognitive tasks
- Medical subject headings
- Cognitive Dysfunction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Five cognitive tasksOther
The five tests are:
- Link's Cube: participants are asked to construct a large cube from 27 smaller cubes such that the outer surface is all the same colour
- Modified Links' Cube: participants are asked to construct a large cube from 9 smaller blocks such that the outer surface is all the same colour, and then amend their response according to 2 further instructions
- D-KEFS Tower Test - participants are asked to move discs of varying sizes across three pegs to build a target tower in as few moves as possible
- Weigl test - participants are asked to sort blocks into one group according to shape/colour and then shift mental set by sorting them according to the second characteristic
- Brixton Spatial Anticipation test - participants are asked to detect rules and rule changes when presented a targets that changes location
| Study group | Role | What they receive |
|---|---|---|
| Neuropsychologists | Other | Clinical psychologists in Gloucestershire Hospitals NHS FT Receives: Other: Five cognitive tasks |
| Non-neuropsychologists | Other | General population, non-neuropsychologists Receives: Other: Five cognitive tasks |
What is being measured
The primary outcome is the main question the study is designed to answer.
Procedural obstacles of the modified Link's Cube test.
Assessed using the Link's Cube Scoring Matrix (total score between 0-30)
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Mar 2026
- Study start15 Sep 2025
- Primary completion1 Apr 2026
- Study completion1 Apr 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cognitive ImpairmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Gloucestershire Hospitals NHS Foundation Trust
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07484048
- Sponsor's protocol ID
- 25/001/GHT
- Other IDs
- 358626
- Status last verified
- Apr 2026
- First submitted
- 29 Jan 2026
- Last updated
- 27 Apr 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Feasibility Study for Development of a Modified Bedside Test of Goal-directed Behaviour
- ClinicalTrials.gov ID
- NCT07484048
- Acronym / sponsor ID
- 25/001/GHT
- Conditions
- Cognitive Impairment, Coginitive Assessment
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Gloucestershire Hospitals NHS Foundation TrustUniversity, hospital or other
- Study start
- 15 Sep 2025 (actual)
- Primary completion
- 1 Apr 2026 (actual)
- Study completion
- 1 Apr 2026 (actual)
- First posted
- 19 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cognitive assessment plays an important part in decision making in acute neurological settings, partly because difficulties with cognitive skills such as attention, memory and executive functioning (which includes planning and problem-solving) have direct implications for patents' levels of independence and safety upon discharge.
A bedside cognitive task that could shed light upon a patient's ability to demonstrate effective goal-directed behaviour (potentially along with other aspects of executive functioning such as cognitive flexibility) would be a useful addition to the existing repertoire of bedside cognitive assessments.
One such test could be 'Link's Cube'. The Link's Cube Test is impractical for bedside use in an acute ward setting, as it comprises 27 small blocks. The feasibility study aims to preserve the information that is provided by Link's Cube Test (i.e. an indication of the patient's ability to engage in goal-directed behaviour) whilst altering the testing material such that only nine, slightly larger blocks are used.
The objectives for the feasibility study are:
- To identify any practical difficulties in administration of the tests that may not be apparent without trialling them
- To generate information regarding the timing and sequence of overall administration and in particular the proposed modified Link's Cube test
- To obtain feedback from neuropsychologists about ease of administration of the proposed new test and to obtain their views regarding potential benefits
Study design
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Neuropsychologists | Other | Other: Five cognitive tasksClinical psychologists in Gloucestershire Hospitals NHS FT |
| Non-neuropsychologists | Other | Other: Five cognitive tasksGeneral population, non-neuropsychologists |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Five cognitive tasksThe five tests are: * Link's Cube: participants are asked to construct a large cube from 27 smaller cubes such that the outer surface is all the same colour * Modified Links' Cube: participants are asked to construct a large cube from 9 smaller blocks such that the outer surface is all the same colour, and then amend their response according to 2 further instructions * D-KEFS Tower Test - participants are asked to move discs of varying sizes across three pegs to build a target tower in as few moves as possible * Weigl test - participants are asked to sort blocks into one group according to shape/colour and then shift mental set by sorting them according to the second characteristic * Brixton Spatial Anticipation test - participants are asked to detect rules and rule changes when presented a targets that changes location | Other | Neuropsychologists, Non-neuropsychologists |
Primary outcome
Procedural obstacles of the modified Link's Cube test.
Time frame: Day 1
Assessed using the Link's Cube Scoring Matrix (total score between 0-30)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Apr 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Five cognitive tasks in people with Cognitive Impairment and Coginitive Assessment, run by Gloucestershire Hospitals NHS Foundation Trust at 2 sites in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Procedural obstacles of the modified Link's Cube test. (time frame: Day 1). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Apr 2026.