Kidney FailureURMNCT07484308
Application and Impact Assessment of Ultrasound Super-Resolution Blood Flow Imaging (URM) in Patients With Renal Failure
A study testing Ultrasound super-resolution blood flow imaging in people with Kidney Failure, run by Ma Zhe at 1 site in China.
Trial summary
The aim of this study is to evaluate the utility of URM technology in imaging renal microcirculatory blood flow in patients with renal failure, and to investigate its clinical feasibility for assessing renal function, disease staging and monitoring treatment response. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Kidney Failure
- What is being tested?
- Ultrasound super-resolution blood flow imaging
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 150 participants
- Where
- 1 siteChina
- Study dates
- 1 Oct 2024to 1 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Inclusion Criteria:① Clinically diagnosed with acute or chronic renal failure; ② Complete laboratory test results and ultrasound images are available.
Exclusion Criteria:① Concurrent severe organ failure; ② Poor image quality; ③ History of renal surgery; ④ Pregnant or breastfeeding women.
Trial locations and contacts
1 site in 1 country.
China1 site
The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province)
Jinan, Shandong
About this study
The aim of this study is to evaluate the utility of URM technology in imaging renal microcirculatory blood flow in patients with renal failure, and to investigate its clinical feasibility for assessing renal function, disease staging and monitoring treatment response.
- Conditions
- Kidney Failure
- Being tested
- Ultrasound super-resolution blood flow imaging
- Keywords
- URM, Kidney failure
- Medical subject headings
- Renal Insufficiency
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound super-resolution blood flow imagingDiagnostic test
Also called Patients with acute kidney failure, Patients with chronic kidney failure
The primary objective is to examine the correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory markers of renal function (eGFR, Scr)
| Study group | Role | What they receive |
|---|---|---|
| Patients with acute kidney failure | Experimental | Not described Receives: Diagnostic Test: Ultrasound super-resolution blood flow imaging |
| Patients with chronic kidney failure | Experimental | Not described Receives: Diagnostic Test: Ultrasound super-resolution blood flow imaging |
What is being measured
The primary outcome is the main question the study is designed to answer.
Correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory renal function markers (eGFR, Scr)
Measured: From enrollment to the end of treatment at 14 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Mar 2026
- Study start1 Oct 2024
- Primary completion1 Oct 2025
- Study completion1 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Kidney FailureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 150 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ma Zhe
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Ma Zhe, Qianfoshan Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07484308
- Sponsor's protocol ID
- YXLL-KY-2026(007)
- Acronym
- URM
- Status last verified
- Mar 2026
- First submitted
- 16 Mar 2026
- Last updated
- 20 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Application and Impact Assessment of Ultrasound Super-Resolution Blood Flow Imaging (URM) in Patients With Renal Failure
- ClinicalTrials.gov ID
- NCT07484308
- Acronym / sponsor ID
- URM / YXLL-KY-2026(007)
- Conditions
- Kidney Failure
- Keywords
- URM, Kidney failure
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 150 participants (actual)
- Lead sponsor
- Ma ZheUniversity, hospital or other
- Study start
- 1 Oct 2024 (actual)
- Primary completion
- 1 Oct 2025 (actual)
- Study completion
- 1 Mar 2026 (actual)
- First posted
- 20 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to evaluate the utility of URM technology in imaging renal microcirculatory blood flow in patients with renal failure, and to investigate its clinical feasibility for assessing renal function, disease staging and monitoring treatment response.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Patients with acute kidney failure | Experimental | Diagnostic Test: Ultrasound super-resolution blood flow imaging |
| Patients with chronic kidney failure | Experimental | Diagnostic Test: Ultrasound super-resolution blood flow imaging |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound super-resolution blood flow imagingAlso: Patients with acute kidney failure, Patients with chronic kidney failureThe primary objective is to examine the correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory markers of renal function (eGFR, Scr) | Diagnostic test | Patients with acute kidney failure, Patients with chronic kidney failure |
Primary outcome
Correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory renal function markers (eGFR, Scr)
Time frame: From enrollment to the end of treatment at 14 days
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultrasound super-resolution blood flow imaging in people with Kidney Failure, run by Ma Zhe at 1 site in China.
The full registered description is in the About this study section and the official record.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory renal function markers (eGFR, Scr) (time frame: From enrollment to the end of treatment at 14 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Mar 2026.