Shoulder Impingement SyndromeNCT07484360
Effects of Kinetic Chain Exercises on Pain, Range of Motion and Disability in Shoulder Impingement Syndrome
A study testing Kinetic chain exercises and conventional physical therapy treatment in people with Shoulder Impingement Syndrome, run by Riphah International University at 1 site in Pakistan.
Trial summary
PROJECT SUMMARY Shoulder pain is secondary only to lower back pain in occurrence. Impingement is one of the most common shoulder disorders. The aim of this study is to evaluate the effects of kinetic chain exercises on pain, ROM and disability in patients with shoulder impingement syndrome which is important in… Read more about this study
- Who is it for?
- Ages 30 to 50 years
- Conditions the study is for
- Shoulder Impingement Syndrome
- What is being tested?
- Kinetic chain exercises and conventional physical therapy treatment
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 sitePakistan
- Study dates
- 10 Jul 2025to 29 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- • Age group 30-50 years
- Males and Females
- Subjects with history of pain in upper lateral aspect of arm with a NPRS score between >3 to <8 on a 0-10 scale
- Neers impingement test positive
- Hawkins- Kennedy test positive
- Painful arc positive
- Empty can (Jobe test) positive
Who cannot join
- • Subjects having Capsular Pattern +ve
- Individuals with OA of GH joint
- Type III acromion process decreasing the sub-acromial space leading to sub-acromial impingement (on X-ray evaluation)
- AC joint arthritis
- Rheumatoid Arthritis
- Fracture history involving upper limb
Show all 9Show fewer
- Shoulder surgery on affected side.
- Subjects with signs of total rotator cuff tears i.e. gross weakness in abduction.
- Subjects who received corticosteroid injections in last three months
Trial locations and contacts
1 site in 1 country.
About this study
PROJECT SUMMARY Shoulder pain is secondary only to lower back pain in occurrence. Impingement is one of the most common shoulder disorders. The aim of this study is to evaluate the effects of kinetic chain exercises on pain, ROM and disability in patients with shoulder impingement syndrome which is important in establishing eveidence for a holistic and potentially more effective rehabilitation method for shoulder impingement syndrome. This study will be a randomized control trial and will be conducted in Riphah International University associated hospital and physiotherapy outpatient department of Jinnah hospital Lahore.
Non probability consecutive sampling will be used. Sample size of 32 subjects with age group 30 to 50 years will be taken. Data will be collected from patients having present complaint of shoulder pain due to shoulder impingement. Outcome measures will be taken using numeric pain rating scale(NPRS) for pain, universal Goniometer for ROM and Shoulder pain and disability index (SPADI) for function. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be equally divided into two groups. Group A will receive kinetic chain exercises (both open and closed chain exercises) and group B will receive conventional physical therapy treatment. Data analysis will be done by SPSS version 28
Read the detailed description
PROJECT SUMMARY Shoulder pain is secondary only to lower back pain in occurrence. Impingement is one of the most common shoulder disorders. The aim of this study is to evaluate the effects of kinetic chain exercises on pain, ROM and disability in patients with shoulder impingement syndrome which is important in establishing eveidence for a holistic and potentially more effective rehabilitation method for shoulder impingement syndrome. This study will be a randomized control trial and will be conducted in Riphah International University associated hospital and physiotherapy outpatient department of Jinnah hospital Lahore.
Non probability consecutive sampling will be used. Sample size of 32 subjects with age group 30 to 50 years will be taken. Data will be collected from patients having present complaint of shoulder pain due to shoulder impingement. Outcome measures will be taken using numeric pain rating scale(NPRS) for pain, universal Goniometer for ROM and Shoulder pain and disability index (SPADI) for function. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be equally divided into two groups. Group A will receive kinetic chain exercises (both open and closed chain exercises) and group B will receive conventional physical therapy treatment. Data analysis will be done by SPSS version 28
- Conditions
- Shoulder Impingement Syndrome
- Being tested
- Kinetic chain exercises, conventional physical therapy treatment
- Keywords
- Disability, Impingement syndrome, Kinetic chain exercises, Pain, Range of Motion
- Medical subject headings
- Shoulder Impingement Syndrome, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Kinetic chain exercisesOther
Kinetic chain exercises work on the stabilizer muscles of scapula, such as the anterior serratus, rhomboids, and trapezius, which are responsible for maintaining the scapula-humeral rhythm. These scapular stabilizers reduce the undesirable movements that would otherwise cause shoulder impingement, therefore reducing stress on the sub-acromial structures. Kinetic chain exercises enhance body's proper movement patterns, improving proprioception, and increase the activation of primary movers. Decreased biomechanical dysfunction results in better arm positioning. By performing exercises that address the entire kinetic chain, these would assist in avoiding the compensatory mechanisms and repetitive strain injuries that act as relapse triggers for SIS. The patients enjoy sustained relief from shoulder impingement syndrome pain and notice less frequency of future shoulder injuries Kinetic chain shoulder therapy exercises involve kinetic link and model called biomechanical model and cranial t
conventional physical therapy treatmentOther
- Heating pad for ten minutes
- Therapeutic ultrasound for 5 minutes
- Active range of motion exercises (two sets of 15 repetitions for each exercise)
- Codman exercises (two sets of 15 repetitions)
| Study group | Role | What they receive |
|---|---|---|
| KINETIC CHAIN EXERCISES (OPEN AND CLOSED) | Experimental | Not described Receives: Other: Kinetic chain exercises; Other: conventional physical therapy treatment |
| CONVENTIONAL PHYSIOTHERAPY TREATMENT | Active comparator | Not described Receives: Other: conventional physical therapy treatment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Numeric Pain Rating scale
. This scale ranges from 0 to 10 where 0 indicating "no pain" and 10 indicating "worst pain possible"
Measured: from start of study to 4 weeks
Shoulder Pain and Disability Index
The Shoulder Pain and Disability Index (SPADI) is a self-administered questionnaire that consisting of two dimensions, one for the pain and other for functional ability of the subject. The pain dimension consists of five questions regarding the severity of an individual's pain intensity
Measured: From start of study upto 4 weeks
Universal Goniometer
Health care practitioners often use universal goniometer to obtain objective measurements of joint range of motion (ROM) to find out the baseline functional status and to measure the effectiveness of treatment interventions
Measured: From start of study upto 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Mar 2026
- Study start10 Jul 2025
- Primary completion29 Dec 2025
- Study completion29 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (10)Papers the sponsor has linked to this study.
- Other trials for Shoulder Impingement SyndromeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Ali Raza, Ms.PT(OM), Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07484360
- Sponsor's protocol ID
- REC/RCR & AHS/24/01100
- Status last verified
- Mar 2026
- First submitted
- 16 Mar 2026
- Last updated
- 20 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Afzalifard, Z., Soltani, A., & Oskouei, A. E. (2023). The effects of magnet therapy on pain and disability in patients with shoulder impingement syndrome. Middle East Journal of Rehabilitation and Health Studies, 10(1).
Mitra D, Mitra P, Rau S. Effect of Specific Exercise Program and Conventional Exercise Protocol on Pain and Disability in Patients with Subacromial Impingement Syndrome
Lo YP, Hsu YC, Chan KM. Epidemiology of shoulder impingement in upper arm sports events. Br J Sports Med. 1990 Sep;24(3):173-7. doi: 10.1136/bjsm.24.3.173.
PubMed 2078803Saadatian A, Babaei Khorzoghi M, Sahebozamani M, Taghi Karimi M. The Impact of OKC Exercises and TRX Exercises on Shoulder Joint Proprioception in Overhead Athletes With Shoulder Impingement Syndrome: A Randomized Controlled Trial. Physical Treatments - Specific Physical Therapy. 2022;12(2):77-84.
Kanthanathan Subbiah SR, AS Subhashini, Sailakshmi Ganeshan. Functional Ability and Quality of Life Status following Manual Therapy and Specific Exercise Conditioning in Subacromial Impingement Syndrome: A Randomised Controlled Study. Journal of Clinical and Diagnostic Research. 2023;17(3):YC11- YC6.
Webb R, Cofre Lizama LE, Galea MP. Moving with ease: feldenkrais method classes for people with osteoarthritis. Evid Based Complement Alternat Med. 2013;2013:479142. doi: 10.1155/2013/479142. Epub 2013 Sep 3.
PubMed 24078825Wen M, Hu X, Bao G. Scapular dyskinesis-based exercise therapy versus multimodal physical therapy for subacromial impingement syndrome in young overhead athletes with scapular dyskinesis: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2025 Jul 16;17(1):204. doi: 10.1186/s13102-025-01254-8.
PubMed 40671042Qamar, M. M., Basharat, A., Kiran, Q., Nazir, A., Ahmad, W., & Basharat, S. (2023). Comparison of the Effects of Conventional Physical Therapy Versus Progressive Overload Training in Patients with Shoulder Impingement Syndrome; A Randomised Clinical Trial. Annals of King Edward Medical University, 29(1), 50-54.
McKim KR. A comprehensive analysis of the swimmers' shoulder [Text]1998.
McMullen J, Uhl TL. A kinetic chain approach for shoulder rehabilitation. J Athl Train. 2000 Jul;35(3):329-37.
PubMed 16558646
Study at a glance
From the registry record, last updated by the sponsor on 20 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Kinetic Chain Exercises on Pain, Range of Motion and Disability in Shoulder Impingement Syndrome
- ClinicalTrials.gov ID
- NCT07484360
- Acronym / sponsor ID
- REC/RCR & AHS/24/01100
- Conditions
- Shoulder Impingement Syndrome
- Keywords
- Disability, Impingement syndrome, Kinetic chain exercises, Pain, Range of Motion
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 10 Jul 2025 (actual)
- Primary completion
- 29 Dec 2025 (actual)
- Study completion
- 29 Dec 2025 (actual)
- First posted
- 20 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
PROJECT SUMMARY Shoulder pain is secondary only to lower back pain in occurrence. Impingement is one of the most common shoulder disorders. The aim of this study is to evaluate the effects of kinetic chain exercises on pain, ROM and disability in patients with shoulder impingement syndrome which is important in establishing eveidence for a holistic and potentially more effective rehabilitation method for shoulder impingement syndrome. This study will be a randomized control trial and will be conducted in Riphah International University associated hospital and physiotherapy outpatient department of Jinnah hospital Lahore.
Non probability consecutive sampling will be used. Sample size of 32 subjects with age group 30 to 50 years will be taken. Data will be collected from patients having present complaint of shoulder pain due to shoulder impingement. Outcome measures will be taken using numeric pain rating scale(NPRS) for pain, universal Goniometer for ROM and Shoulder pain and disability index (SPADI) for function. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be equally divided into two groups. Group A will receive kinetic chain exercises (both open and closed chain exercises) and group B will receive conventional physical therapy treatment. Data analysis will be done by SPSS version 28
Detailed description
PROJECT SUMMARY Shoulder pain is secondary only to lower back pain in occurrence. Impingement is one of the most common shoulder disorders. The aim of this study is to evaluate the effects of kinetic chain exercises on pain, ROM and disability in patients with shoulder impingement syndrome which is important in establishing eveidence for a holistic and potentially more effective rehabilitation method for shoulder impingement syndrome. This study will be a randomized control trial and will be conducted in Riphah International University associated hospital and physiotherapy outpatient department of Jinnah hospital Lahore.
Non probability consecutive sampling will be used. Sample size of 32 subjects with age group 30 to 50 years will be taken. Data will be collected from patients having present complaint of shoulder pain due to shoulder impingement. Outcome measures will be taken using numeric pain rating scale(NPRS) for pain, universal Goniometer for ROM and Shoulder pain and disability index (SPADI) for function. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be equally divided into two groups. Group A will receive kinetic chain exercises (both open and closed chain exercises) and group B will receive conventional physical therapy treatment. Data analysis will be done by SPSS version 28
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| KINETIC CHAIN EXERCISES (OPEN AND CLOSED) | Experimental | Other: Kinetic chain exercises, Other: conventional physical therapy treatment |
| CONVENTIONAL PHYSIOTHERAPY TREATMENT | Active comparator | Other: conventional physical therapy treatment |
Who may qualify
- Ages
- 30 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- • Age group 30-50 years
Key exclusion criteria (9 listed)
- • Subjects having Capsular Pattern +ve
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Kinetic chain exercisesKinetic chain exercises work on the stabilizer muscles of scapula, such as the anterior serratus, rhomboids, and trapezius, which are responsible for maintaining the scapula-humeral rhythm. These scapular stabilizers reduce the undesirable movements that would otherwise cause shoulder impingement, therefore reducing stress on the sub-acromial structures. Kinetic chain exercises enhance body's proper movement patterns, improving proprioception, and increase the activation of primary movers. Decreased biomechanical dysfunction results in better arm positioning. By performing exercises that address the entire kinetic chain, these would assist in avoiding the compensatory mechanisms and repetitive strain injuries that act as relapse triggers for SIS. The patients enjoy sustained relief from shoulder impingement syndrome pain and notice less frequency of future shoulder injuries Kinetic chain shoulder therapy exercises involve kinetic link and model called biomechanical model and cranial t | Other | KINETIC CHAIN EXERCISES (OPEN AND CLOSED) |
| conventional physical therapy treatment* Heating pad for ten minutes * Therapeutic ultrasound for 5 minutes * Active range of motion exercises (two sets of 15 repetitions for each exercise) * Codman exercises (two sets of 15 repetitions) | Other | CONVENTIONAL PHYSIOTHERAPY TREATMENT, KINETIC CHAIN EXERCISES (OPEN AND CLOSED) |
Primary outcome
Numeric Pain Rating scale
Time frame: from start of study to 4 weeks
. This scale ranges from 0 to 10 where 0 indicating "no pain" and 10 indicating "worst pain possible"
Shoulder Pain and Disability Index
Time frame: From start of study upto 4 weeks
The Shoulder Pain and Disability Index (SPADI) is a self-administered questionnaire that consisting of two dimensions, one for the pain and other for functional ability of the subject. The pain dimension consists of five questions regarding the severity of an individual's pain intensity
Universal Goniometer
Time frame: From start of study upto 4 weeks
Health care practitioners often use universal goniometer to obtain objective measurements of joint range of motion (ROM) to find out the baseline functional status and to measure the effectiveness of treatment interventions
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Mar 2026.
- BackgroundAfzalifard, Z., Soltani, A., & Oskouei, A. E. (2023). The effects of magnet therapy on pain and disability in patients with shoulder impingement syndrome. Middle East Journal of Rehabilitation and Health Studies, 10(1).
- BackgroundMitra D, Mitra P, Rau S. Effect of Specific Exercise Program and Conventional Exercise Protocol on Pain and Disability in Patients with Subacromial Impingement Syndrome
- Background: PubMed 2078803Lo YP, Hsu YC, Chan KM. Epidemiology of shoulder impingement in upper arm sports events. Br J Sports Med. 1990 Sep;24(3):173-7. doi: 10.1136/bjsm.24.3.173.
- BackgroundSaadatian A, Babaei Khorzoghi M, Sahebozamani M, Taghi Karimi M. The Impact of OKC Exercises and TRX Exercises on Shoulder Joint Proprioception in Overhead Athletes With Shoulder Impingement Syndrome: A Randomized Controlled Trial. Physical Treatments - Specific Physical Therapy. 2022;12(2):77-84.
- BackgroundKanthanathan Subbiah SR, AS Subhashini, Sailakshmi Ganeshan. Functional Ability and Quality of Life Status following Manual Therapy and Specific Exercise Conditioning in Subacromial Impingement Syndrome: A Randomised Controlled Study. Journal of Clinical and Diagnostic Research. 2023;17(3):YC11- YC6.
- Background: PubMed 24078825Webb R, Cofre Lizama LE, Galea MP. Moving with ease: feldenkrais method classes for people with osteoarthritis. Evid Based Complement Alternat Med. 2013;2013:479142. doi: 10.1155/2013/479142. Epub 2013 Sep 3.
- Background: PubMed 40671042Wen M, Hu X, Bao G. Scapular dyskinesis-based exercise therapy versus multimodal physical therapy for subacromial impingement syndrome in young overhead athletes with scapular dyskinesis: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2025 Jul 16;17(1):204. doi: 10.1186/s13102-025-01254-8.
- BackgroundQamar, M. M., Basharat, A., Kiran, Q., Nazir, A., Ahmad, W., & Basharat, S. (2023). Comparison of the Effects of Conventional Physical Therapy Versus Progressive Overload Training in Patients with Shoulder Impingement Syndrome; A Randomised Clinical Trial. Annals of King Edward Medical University, 29(1), 50-54.
- BackgroundMcKim KR. A comprehensive analysis of the swimmers' shoulder [Text]1998.
- Background: PubMed 16558646McMullen J, Uhl TL. A kinetic chain approach for shoulder rehabilitation. J Athl Train. 2000 Jul;35(3):329-37.
- Individual participant dataSharing planned: No
Related trials for Shoulder Impingement Syndrome
Not yet recruiting
TECAR With Shoulder Chronic Shoulder Impingement Syndrome
Shoulder Impingement Syndrome
Recruiting
Device-Assisted Balance Training for People With Shoulder Impingement
Shoulder
Not yet recruiting
"Effectiveness of a Telerehabilitation Program Versus a Conventional Rehabilitation Program in Patients With Subacromial Pain"
Subacromial Impingement Syndrome
Active, not recruitingObservational study
Natural History of Shoulder Pathology in Manual Wheelchair Users
Paraplegia, Spinal Cord Injuries
Not yet recruiting
Spencer vs Positional Release Techniques for Chronic Subacromial Impingement
Chronic Subacromial Impingement Syndrome
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Ali Raza, Ms.PT(OM) principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Kinetic chain exercises and conventional physical therapy treatment in people with Shoulder Impingement Syndrome, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Numeric Pain Rating scale (time frame: from start of study to 4 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07484360, which also lists 10 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Mar 2026.