Stroke, CerebrovascularDTOCT-StrokeNCT07494357
Effects of Dual Task-Oriented Circuit Training on Walking Recovery in Sub-acute Stroke
A study testing Dual task oriented circuit training, Task Oriented Circuit Training and Dual task training in people with Stroke, Cerebrovascular, run by Universitas Padjadjaran at 1 site in Indonesia.
Trial summary
This pilot study aims to assess the feasibility, safety, and initial efficacy of an integrated Dual Task-Oriented Circuit Training (DTOCT) program for individuals in the subacute phase of stroke recovery. Read more about this study
- Who is it for?
- Ages 40 to 65 years
- Conditions the study is for
- Stroke, Cerebrovascular
- What is being tested?
- Dual task oriented circuit training, Task Oriented Circuit Training and Dual task training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteIndonesia
- Study dates
- 1 Jun 2026to 30 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosed with a first-ever subacute stroke (defined as 2 weeks to 5 months post-onset) with anterior circulation involvement.
- Diagnosis confirmed via neuroimaging (CT or MRI).
- Men and women aged 40 to 65 years.
- Motor recovery in the lower limbs corresponding to Brunnstrom stages 4 to
- Functional Ambulation Category (FAC) score of at least grade 3.
- Ability to walk independently, with or without walking aids.
- Montreal Cognitive Assessment Indonesian version (MoCA-INA) score of ≥20, demonstrating the capacity to collaborate and follow multi-step instructions.
- Medically stable with controlled comorbidities.
Who cannot join
- Expressive or receptive aphasia that impedes task comprehension
- Unstable cardiovascular or medical conditions (e.g., severe hypertension, congestive heart failure) for which moderate exercise is contraindicated.
- Moderate to severe depression, indicated by a Patient Health Questionnaire-9 (PHQ-9) score of ≥ 15.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Indonesia1 site
RS Dustira Bandung
Bandung, West Java, 40131
Bernadeta Cahyo Setianingrum Poernomo, MD, PMR, +6281214544779, nuningbernadeta@ymail.com
About this study
Official title: The Effect of Dual Task-Oriented Circuit Training on Neuroplasticity and Walking Adaptability in Subacute Stroke Patients: A Pilot and Feasibility Study
This pilot study aims to assess the feasibility, safety, and initial efficacy of an integrated Dual Task-Oriented Circuit Training (DTOCT) program for individuals in the subacute phase of stroke recovery. Although numerous patients recover the capacity to walk in a regulated hospital environment, they frequently encounter difficulties with "community ambulation," the capability to traverse real-world settings while multitasking (e.g., walking while conversing or circumventing barriers). This study will examine if the integration of high-intensity circuit training with cognitive difficulties can promote neuroplasticity and enhance the patient's capacity to safely traverse intricate daily settings.
Read the detailed description
Cognitive-Motor Interference (CMI) makes it challenging for stroke survivors to reintegrate into their communities. Walking is an automatic subcortical process in a healthy brain. After a stroke, however, the brain often has to "consciously" control walking, which takes away mental resources from other tasks. This "functional gap" is why almost 80% of survivors can walk house-hold, but only 30% can safely get around in the community. This study examines the "Golden Window" of recovery (2 weeks to 5 months post-stroke), a timeframe characterized by optimal physiological conditions for neuroplasticity. The DTOCT protocol functions as a synergistic intervention: the circuit training induces cardiovascular intensity to stimulate systemic Brain-Derived Neurotrophic Factor (BDNF) release, while concurrent cognitive tasks (e.g., memory recall or the Stroop test) focus on localized neurotrophic support within the prefrontal cortex and hippocampus. This three-arm pilot study (DTOCT vs. pure task-oriented training vs. pure dual-tasking) will give us important information about how easy it is to recruit participants, how well they stick to the plan, and how big the initial effects are. These results will constitute an essential basis for an upcoming comprehensive Randomized Controlled Trial (RCT) designed to enhance the standard of neurorehabilitation in Indonesia.
- Conditions
- Stroke, Cerebrovascular
- Being tested
- Dual task oriented circuit training, Task Oriented Circuit Training, Dual task training
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dual task oriented circuit trainingBehavioural
Also called DTOCT
- Experimental Arm: Dual Task-Oriented Circuit Training (DTOCT) Intervention Name: Behavioral: Dual Task-Oriented Circuit Training (DTOCT)
Description:
Participants will undergo an integrated 60-minute rehabilitation session, 3 times per week for 4 weeks (total 12 sessions). Each session includes 25-50 minutes of active circuit training across five specialized stations:
Dual-Task Walking: Straight walking (3-8m) while performing forward/backward number sequencing.
Obstacle Walking: Stepping over cone or hurdle obstacles (5-14cm) while naming object categories from long-term memory.
Stair Navigation: Ascending/descending stairs (10-17cm step height) while identifying colors and shapes.
Walking with Navigation: Navigating an oval path (3-8m) while performing an incongruent Stroop color-word task.
ADL Stimulation: Walking while carrying a cup of liquid or a shopping bag to train executive function and working memory.
Training intensity and cognitive difficulty are progressed weekly
Task Oriented Circuit TrainingBehavioural
Also called TOCT
- Active Comparator Arm: Task-Oriented Circuit Training (TOCT) Intervention Name: Behavioral: Task-Oriented Circuit Training (TOCT)
Description:
Participants will focus exclusively on functional motor relearning and cardiovascular endurance through 6 circuit-based stations:
Standing and Reaching: Multidirectional reaching to targets while standing. Sit-to-Stand: Transitions using chairs of various heights to strengthen extensors.
Anterior/Posterior Stepping: Stepping onto blocks of various heights. Lateral Stepping: Side-stepping for lateral stability. Forward Step-Up: Strengthening for stair climbing mechanics. Heel Raise: Improving gait push-off mechanics.
Each station is performed for 2.5 to 5 minutes with 1-minute rest periods. Training is conducted 3 times per week for 4 weeks (total 12 sessions), with each session lasting 60 minutes including warm-up and cool-down. No explicit secondary cognitive tasks are added.
Dual task trainingBehavioural
Also called DTT
- Active Comparator Arm: Pure Dual-Task Training (DT) Intervention Name: Behavioral: Pure Dual-Task Training (DT)
Description:
Participants will perform standard, non-circuit walking at a self-selected comfortable speed while executing simultaneous cognitive demands. The protocol includes:
Backward Counting: Continuous subtraction from a random 3-digit number. Stroop Task: Identifying font colors or semantic meanings of incongruent words. Memory Tasks: Sequential recall of shopping lists (3-5 items) and reverse word recall (2-4 words).
Verbal Fluency: Generating word chains or category naming.
Each session consists of two 15-minute sets of core dual-task training (30 minutes total activity) within a 60-minute therapist-supervised visit. Training is conducted 3 times per week for 4 weeks (total 12 sessions). Cognitive difficulty is adjusted weekly to maintain an optimal challenge.
| Study group | Role | What they receive |
|---|---|---|
| Dual Task Oriented Circuit Training (DTOCT) | Experimental | Experimental: DTOCT Behavioral: Dual Task-Oriented Circuit Training. Participants engage in 5 circuit stations (e.g., obstacle walking, stair navigation) while performing secondary cognitive tasks (e.g., backward counting, object naming). 3 sessions/week for 4 weeks. Receives: Behavioral: Dual task oriented circuit training |
| Task Orinted Circuit Training (TOCT) | Active comparator | Behavioral: Task-Oriented Circuit Training. Focuses on high-intensity motor repetition using circuit stations (e.g., sit-to-stand, stepping) without added cognitive load. Receives: Behavioral: Task Oriented Circuit Training |
| Dual Task Training (DTT) | Active comparator | Behavioral: Pure Dual-Task Training. Participants practice walking under cognitive load (e.g., Stroop task) in a standard non-circuit format. Receives: Behavioral: Dual task training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Adherence Rate
Description: Percentage of attended sessions (out of 12) during the 4-week intervention period.
Measured: 4 weeks
Retention Rate
Proportion of participants who complete the full 4-week protocol and follow-up assessments
Measured: 4 weeks
Incidence of Adverse Events
Frequency of falls or medical adverse events documented during the training sessions.
Measured: 4 weeks
Mean Exercise Heart Rate
Evaluation of cardiovascular demand and tolerability during the circuit training stations. Measured using a digital heart rate monitor.
Unit of Measure: Beats per minute (bpm)
Measured: During each of the 12 training sessions (4 weeks)
Mean Systolic and Diastolic Blood Pressure
Monitoring of hemodynamic stability to ensure the high-intensity circuit training is safe for subacute stroke patients Unit of Measure: Millimeters of mercury (mmHg)
Measured: Pre-and post-each training session (4 weeks)
Mean Borg Rating of Perceived Exertion (RPE) Score
Assessment of subjective physical effort and tolerability. The scale ranges from 6 to 20 (or 0-10 depending on the version used), where higher scores indicate greater perceived exertion.
Unit of Measure: Units on a scale
Measured: At the end of each circuit station during all 12 sessions (4 weeks)
Secondary outcomes (6)
Change from Baseline in 6-Minute Walk Test (6MWT)
Change in total distance walked in meters during the 6-Minute Walk Test from baseline to 4 weeks.
Measured: Baseline and 4 weeks
Change from Baseline in 10-Meter Walk Test (10MWT)
Change in gait speed measured in meters per second (m/s) in 10 meter walk test
Measured: Baseline and 4 weeks
Change from Baseline of Completion Time in Standardized Walking Obstacle Course (SWOC)
Mean time taken to complete the 12.2-meter curved course across three conditions (normal, tray, dark-glasses) and measured using a stopwatch. The total time in seconds taken to complete the 12.2-meter curved obstacle course under three conditions (normal, tray, and dark-glasses). A shorter time indicates better walking adaptability.
Unit of Measure: Seconds
Measured: Baseline and 4 weeks
Change from Baseline in Standardized Walking Obstacle Course (SWOC) Step Count
Mean number of contacts between the foot and ground during course completion across three conditions Unit of measure : Number of steps
Measured: Baseline and 4 weeks
Change of number of errors in Standardized Walking Obstacle Course (SWOC)
Errors are operationally defined as the aggregate sum of "stumbles" (where the participant's leg or walking aid strikes an obstacle) and "step-offs" (where a whole foot is placed outside the 0.92-meter wide curved pathway) Number of errors (atau "Count of errors")
Measured: Baseline and 4 weeks (Post-intervention)
Change from Baseline in Serum BDNF Concentration
Concentration of Brain-Derived Neurotrophic Factor quantified via sandwich ELISA to measure neuroplasticity.
Unit of measure : Picograms per milliliter (pg/mL)
Measured: Baseline and 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Mar 2026
- Study start1 Jun 2026 (estimated)
- Primary completion30 Aug 2026 (estimated)
- Study completion30 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Stroke, CerebrovascularStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Parallel asgnment
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 36 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Universitas Padjadjaran
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Farida Arisanti, Universitas Padjadjaran
- Investigators
- Farida Arisanti, MD, PMR, Principal investigator, Universitas Padjadjaran
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07494357
- Sponsor's protocol ID
- IKFR-202603.01
- Acronym
- DTOCT-Stroke
- Status last verified
- May 2026
- First submitted
- 14 Mar 2026
- Last updated
- 28 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Arisanti F, Ropii B, Ghaida S, Tristiana Dewi T, Poernomo BCS, Sribudiani Y, Amalia L, Engkasan JP, Biben V. The effect of dual task-oriented circuit training on neuroplasticity and walking adaptability in subacute stroke patients: A pilot and feasibility study. PLoS One. 2026 Oct 27;21(10):e0361255. doi: 10.1371/journal.pone.0361255. eCollection 2026.
PubMed 42945228
Study at a glance
From the registry record, last updated by the sponsor on 28 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Dual Task-Oriented Circuit Training on Neuroplasticity and Walking Adaptability in Subacute Stroke Patients: A Pilot and Feasibility Study
- ClinicalTrials.gov ID
- NCT07494357
- Acronym / sponsor ID
- DTOCT-Stroke / IKFR-202603.01
- Conditions
- Stroke, Cerebrovascular
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 36 participants (estimated)
- Lead sponsor
- Universitas PadjadjaranUniversity, hospital or other
- Study start
- 1 Jun 2026 (estimated)
- Primary completion
- 30 Aug 2026 (estimated)
- Study completion
- 30 Aug 2026 (estimated)
- First posted
- 27 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This pilot study aims to assess the feasibility, safety, and initial efficacy of an integrated Dual Task-Oriented Circuit Training (DTOCT) program for individuals in the subacute phase of stroke recovery. Although numerous patients recover the capacity to walk in a regulated hospital environment, they frequently encounter difficulties with "community ambulation," the capability to traverse real-world settings while multitasking (e.g., walking while conversing or circumventing barriers). This study will examine if the integration of high-intensity circuit training with cognitive difficulties can promote neuroplasticity and enhance the patient's capacity to safely traverse intricate daily settings.
Detailed description
Cognitive-Motor Interference (CMI) makes it challenging for stroke survivors to reintegrate into their communities. Walking is an automatic subcortical process in a healthy brain. After a stroke, however, the brain often has to "consciously" control walking, which takes away mental resources from other tasks. This "functional gap" is why almost 80% of survivors can walk house-hold, but only 30% can safely get around in the community. This study examines the "Golden Window" of recovery (2 weeks to 5 months post-stroke), a timeframe characterized by optimal physiological conditions for neuroplasticity. The DTOCT protocol functions as a synergistic intervention: the circuit training induces cardiovascular intensity to stimulate systemic Brain-Derived Neurotrophic Factor (BDNF) release, while concurrent cognitive tasks (e.g., memory recall or the Stroop test) focus on localized neurotrophic support within the prefrontal cortex and hippocampus. This three-arm pilot study (DTOCT vs. pure task-oriented training vs. pure dual-tasking) will give us important information about how easy it is to recruit participants, how well they stick to the plan, and how big the initial effects are. These results will constitute an essential basis for an upcoming comprehensive Randomized Controlled Trial (RCT) designed to enhance the standard of neurorehabilitation in Indonesia.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
- Model description
- Parallel asgnment
| Arm | Type | Receives |
|---|---|---|
| Dual Task Oriented Circuit Training (DTOCT) | Experimental | Behavioral: Dual task oriented circuit trainingExperimental: DTOCT Behavioral: Dual Task-Oriented Circuit Training. Participants engage in 5 circuit stations (e.g., obstacle walking, stair navigation) while performing secondary cognitive tasks (e.g., backward counting, object naming). 3 sessions/week for 4 weeks. |
| Task Orinted Circuit Training (TOCT) | Active comparator | Behavioral: Task Oriented Circuit TrainingBehavioral: Task-Oriented Circuit Training. Focuses on high-intensity motor repetition using circuit stations (e.g., sit-to-stand, stepping) without added cognitive load. |
| Dual Task Training (DTT) | Active comparator | Behavioral: Dual task trainingBehavioral: Pure Dual-Task Training. Participants practice walking under cognitive load (e.g., Stroop task) in a standard non-circuit format. |
Who may qualify
- Ages
- 40 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Diagnosed with a first-ever subacute stroke (defined as 2 weeks to 5 months post-onset) with anterior circulation involvement.
- Diagnosis confirmed via neuroimaging (CT or MRI).
- Men and women aged 40 to 65 years.
- Motor recovery in the lower limbs corresponding to Brunnstrom stages 4 to
- Functional Ambulation Category (FAC) score of at least grade 3.
Key exclusion criteria (3 listed)
- Expressive or receptive aphasia that impedes task comprehension
- Unstable cardiovascular or medical conditions (e.g., severe hypertension, congestive heart failure) for which moderate exercise is contraindicated.
- Moderate to severe depression, indicated by a Patient Health Questionnaire-9 (PHQ-9) score of ≥ 15.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dual task oriented circuit trainingAlso: DTOCT1. Experimental Arm: Dual Task-Oriented Circuit Training (DTOCT) Intervention Name: Behavioral: Dual Task-Oriented Circuit Training (DTOCT) Description: Participants will undergo an integrated 60-minute rehabilitation session, 3 times per week for 4 weeks (total 12 sessions). Each session includes 25-50 minutes of active circuit training across five specialized stations: Dual-Task Walking: Straight walking (3-8m) while performing forward/backward number sequencing. Obstacle Walking: Stepping over cone or hurdle obstacles (5-14cm) while naming object categories from long-term memory. Stair Navigation: Ascending/descending stairs (10-17cm step height) while identifying colors and shapes. Walking with Navigation: Navigating an oval path (3-8m) while performing an incongruent Stroop color-word task. ADL Stimulation: Walking while carrying a cup of liquid or a shopping bag to train executive function and working memory. Training intensity and cognitive difficulty are progressed weekly | Behavioural | Dual Task Oriented Circuit Training (DTOCT) |
| Task Oriented Circuit TrainingAlso: TOCT2. Active Comparator Arm: Task-Oriented Circuit Training (TOCT) Intervention Name: Behavioral: Task-Oriented Circuit Training (TOCT) Description: Participants will focus exclusively on functional motor relearning and cardiovascular endurance through 6 circuit-based stations: Standing and Reaching: Multidirectional reaching to targets while standing. Sit-to-Stand: Transitions using chairs of various heights to strengthen extensors. Anterior/Posterior Stepping: Stepping onto blocks of various heights. Lateral Stepping: Side-stepping for lateral stability. Forward Step-Up: Strengthening for stair climbing mechanics. Heel Raise: Improving gait push-off mechanics. Each station is performed for 2.5 to 5 minutes with 1-minute rest periods. Training is conducted 3 times per week for 4 weeks (total 12 sessions), with each session lasting 60 minutes including warm-up and cool-down. No explicit secondary cognitive tasks are added. | Behavioural | Task Orinted Circuit Training (TOCT) |
| Dual task trainingAlso: DTT3. Active Comparator Arm: Pure Dual-Task Training (DT) Intervention Name: Behavioral: Pure Dual-Task Training (DT) Description: Participants will perform standard, non-circuit walking at a self-selected comfortable speed while executing simultaneous cognitive demands. The protocol includes: Backward Counting: Continuous subtraction from a random 3-digit number. Stroop Task: Identifying font colors or semantic meanings of incongruent words. Memory Tasks: Sequential recall of shopping lists (3-5 items) and reverse word recall (2-4 words). Verbal Fluency: Generating word chains or category naming. Each session consists of two 15-minute sets of core dual-task training (30 minutes total activity) within a 60-minute therapist-supervised visit. Training is conducted 3 times per week for 4 weeks (total 12 sessions). Cognitive difficulty is adjusted weekly to maintain an optimal challenge. | Behavioural | Dual Task Training (DTT) |
Primary outcome
Adherence Rate
Time frame: 4 weeks
Description: Percentage of attended sessions (out of 12) during the 4-week intervention period.
Retention Rate
Time frame: 4 weeks
Proportion of participants who complete the full 4-week protocol and follow-up assessments
Incidence of Adverse Events
Time frame: 4 weeks
Frequency of falls or medical adverse events documented during the training sessions.
Mean Exercise Heart Rate
Time frame: During each of the 12 training sessions (4 weeks)
Evaluation of cardiovascular demand and tolerability during the circuit training stations. Measured using a digital heart rate monitor. Unit of Measure: Beats per minute (bpm)
Mean Systolic and Diastolic Blood Pressure
Time frame: Pre-and post-each training session (4 weeks)
Monitoring of hemodynamic stability to ensure the high-intensity circuit training is safe for subacute stroke patients Unit of Measure: Millimeters of mercury (mmHg)
Mean Borg Rating of Perceived Exertion (RPE) Score
Time frame: At the end of each circuit station during all 12 sessions (4 weeks)
Assessment of subjective physical effort and tolerability. The scale ranges from 6 to 20 (or 0-10 depending on the version used), where higher scores indicate greater perceived exertion. Unit of Measure: Units on a scale
6 secondary outcomes
Change from Baseline in 6-Minute Walk Test (6MWT)
Time frame: Baseline and 4 weeks
Change from Baseline in 10-Meter Walk Test (10MWT)
Time frame: Baseline and 4 weeks
Change from Baseline of Completion Time in Standardized Walking Obstacle Course (SWOC)
Time frame: Baseline and 4 weeks
Change from Baseline in Standardized Walking Obstacle Course (SWOC) Step Count
Time frame: Baseline and 4 weeks
Change of number of errors in Standardized Walking Obstacle Course (SWOC)
Time frame: Baseline and 4 weeks (Post-intervention)
Change from Baseline in Serum BDNF Concentration
Time frame: Baseline and 4 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 May 2026.
- Derived from this study: PubMed 42945228Arisanti F, Ropii B, Ghaida S, Tristiana Dewi T, Poernomo BCS, Sribudiani Y, Amalia L, Engkasan JP, Biben V. The effect of dual task-oriented circuit training on neuroplasticity and walking adaptability in subacute stroke patients: A pilot and feasibility study. PLoS One. 2026 Oct 27;21(10):e0361255. doi: 10.1371/journal.pone.0361255. eCollection 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Farida Arisanti, MD, PMR principal investigator
Universitas Padjadjaran
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Dual task oriented circuit training, Task Oriented Circuit Training and Dual task training in people with Stroke, Cerebrovascular, run by Universitas Padjadjaran at 1 site in Indonesia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 28 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Indonesia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Farida Arisanti, MD, PMR (+62-85351111946, farida.arisanti@unpad.ac.id), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Adherence Rate (time frame: 4 weeks). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07494357, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 May 2026.