Q-angleNCT07500597
Regional Associations Between Q-Angle and Plantar Loading in Active Young Adults
An observational study of Q-angle and Plantar Loading Patterns, run by Harran University at 1 site in Turkey (Türkiye).
Trial summary
This observational study aims to examine the association between Q-angle and plantar loading characteristics in physically active young adults. Q-angle is a commonly used clinical measure of lower-extremity alignment, but its relationship with regional plantar loading during gait remains unclear. Read more about this study
- Who is it for?
- Ages 18 to 27 yearsHealthy volunteers can take part
- Conditions the study is for
- Q-angle, Plantar Loading Patterns
- What is being tested?
- Q-angle and plantar pressure assessment
- How many people
- 92 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 22 Dec 2025to 6 Mar 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 27 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Physically active young adults aged 18 years and older who were able to walk independently and had no current lower-extremity injury, neurological disorder, or other condition affecting gait or plantar loading. Participants underwent Q-angle measurement and plantar pressure assessment during walking.
Who may be able to join
- being within the predefined young age range, (2) being physically active according to the IPAQ-SF based assessment, and (3) willingness to participate voluntarily.
Who cannot join
- history of lower extremity injury within the previous 6 months, (2) previous lower extremity surgery, (3) known neurological or vestibular disorder affecting gait or balance, (4) current musculoskeletal pain in the spine or lower extremities during assessment, (5) diagnosed structural lower extremity deformity, and (6) inability to complete the assessment procedures independently.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Marmara University, Faculty of Health Sciences
Istanbul, 34864
About this study
Official title: Region-Specific Associations Between Q-Angle and Plantar Loading in Physically Active Young Adults
This observational study aims to examine the association between Q-angle and plantar loading characteristics in physically active young adults. Q-angle is a commonly used clinical measure of lower-extremity alignment, but its relationship with regional plantar loading during gait remains unclear. Participants will undergo bilateral Q-angle assessment and plantar pressure evaluation during walking. The study will investigate whether Q-angle is associated with specific plantar loading variables across different foot regions in active young adults.
Read the detailed description
This observational study is designed to investigate the association between Q-angle and plantar loading characteristics in physically active young adults. Q-angle is a commonly used measure of lower-extremity alignment, but its relationship with regional plantar loading during gait has not been fully clarified.
Participants will undergo bilateral Q-angle assessment under standardized conditions and dynamic pedobarographic evaluation during walking. Plantar pressure variables will be obtained for different foot regions, including the toes, forefoot, midfoot, hindfoot, and total foot. The primary objective is to determine whether Q-angle is associated with selected regional plantar loading variables. Secondary analyses will explore whether these associations differ according to sex and limb dominance.
Statistical analyses will be performed using linear mixed-effects models to account for within-subject dependence between bilateral measurements.This study focuses on the relationship between lower-extremity alignment and regional plantar loading patterns in physically active young adults.
- Conditions
- Q-angle, Plantar Loading Patterns
- Being tested
- Q-angle and plantar pressure assessment
- Keywords
- Q angle, Plantar loading, Pedobarography, Lower extremity alignment, Foot biomechanics, Young adults
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Q-angle and plantar pressure assessmentDiagnostic test
Participants underwent Q-angle measurement and plantar pressure assessment during walking for observational evaluation. No therapeutic or preventive intervention was applied.
| Study group | Role | What they receive |
|---|---|---|
| Physically active young adults | Physically active young adults who underwent Q-angle measurement and plantar pressure assessment during walking. No therapeutic intervention was applied. Receives: Diagnostic Test: Q-angle and plantar pressure assessment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Association between Q-angle and regional pedobarography outcomes
Regional plantar pressure, force, contact area, and contact time outcomes assessed in relation to Q-angle.
Measured: At baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Mar 2026
- Study start22 Dec 2025
- Primary completion23 Jan 2026
- Study completion6 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (8)Papers the sponsor has linked to this study.
- Other trials for Q-angleStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 92 participants (actual)
Sponsor and investigators
- Lead sponsor
- Harran University
- Sponsor type
- University, hospital or other
- Collaborators
- Marmara University
- Responsible party
- Principal investigator, Veysel Akduman, Harran University
- Investigators
- Veysel Akduman, PhD, Principal investigator, Marmara UniversityVeysel akduman, PhD, Principal investigator, Harran University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07500597
- Sponsor's protocol ID
- HRÜ/25.20.26
- Other IDs
- HRÜ/25.20.26
- Status last verified
- Mar 2026
- First submitted
- 18 Mar 2026
- Last updated
- 30 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Individual participant data sharing has not yet been determined. Any future data sharing will depend on ethical approval, participant consent, institutional policies, and data de-identification requirements.
Publications
Dowling GJ, Murley GS, Munteanu SE, Smith MM, Neal BS, Griffiths IB, Barton CJ, Collins NJ. Dynamic foot function as a risk factor for lower limb overuse injury: a systematic review. J Foot Ankle Res. 2014 Dec 19;7(1):53. doi: 10.1186/s13047-014-0053-6. eCollection 2014.
PubMed 25598843Harvey HD, Game C, Walsh TP, Wearing SC, Platt SR. Are models of plantar heel pain suitable for competitive runners? A narrative review. J Orthop. 2022 Jun 21;33:9-14. doi: 10.1016/j.jor.2022.06.011. eCollection 2022 Sep-Oct.
PubMed 35789776Freedman BR, Brindle TJ, Sheehan FT. Re-evaluating the functional implications of the Q-angle and its relationship to in-vivo patellofemoral kinematics. Clin Biomech (Bristol). 2014 Dec;29(10):1139-45. doi: 10.1016/j.clinbiomech.2014.09.012. Epub 2014 Oct 7.
PubMed 25451861Hu Z, Zhang Y, Dong T, Dong M, Kim S, Kim Y. Gender Differences in Neuromuscular Control during the Preparation Phase of Single-Leg Landing Task in Badminton. J Clin Med. 2023 May 5;12(9):3296. doi: 10.3390/jcm12093296.
PubMed 37176736Lee OE, Braun TM. Permutation tests for random effects in linear mixed models. Biometrics. 2012 Jun;68(2):486-93. doi: 10.1111/j.1541-0420.2011.01675.x. Epub 2011 Sep 27.
PubMed 21950470Setia MS. Methodology Series Module 3: Cross-sectional Studies. Indian J Dermatol. 2016 May-Jun;61(3):261-4. doi: 10.4103/0019-5154.182410.
PubMed 27293245Cen X, Xu D, Baker JS, Gu Y. Association of Arch Stiffness with Plantar Impulse Distribution during Walking, Running, and Gait Termination. Int J Environ Res Public Health. 2020 Mar 21;17(6):2090. doi: 10.3390/ijerph17062090.
PubMed 32245235Akduman V, Karakoc ZB, Senocak E, Mete E, Acar G. Region-specific associations between Q-angle and plantar loading in physically active young adults. J Biomech. 2026 Oct 8;208:113611. doi: 10.1016/j.jbiomech.2026.113611. Online ahead of print.
PubMed 42854518
Study at a glance
From the registry record, last updated by the sponsor on 30 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Region-Specific Associations Between Q-Angle and Plantar Loading in Physically Active Young Adults
- ClinicalTrials.gov ID
- NCT07500597
- Acronym / sponsor ID
- HRÜ/25.20.26
- Conditions
- Q-angle, Plantar Loading Patterns
- Keywords
- Q angle, Plantar loading, Pedobarography, Lower extremity alignment, Foot biomechanics, Young adults
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 92 participants (actual)
- Lead sponsor
- Harran UniversityUniversity, hospital or other
- Collaborators
- Marmara University
- Study start
- 22 Dec 2025 (actual)
- Primary completion
- 23 Jan 2026 (actual)
- Study completion
- 6 Mar 2026 (actual)
- First posted
- 30 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational study aims to examine the association between Q-angle and plantar loading characteristics in physically active young adults. Q-angle is a commonly used clinical measure of lower-extremity alignment, but its relationship with regional plantar loading during gait remains unclear. Participants will undergo bilateral Q-angle assessment and plantar pressure evaluation during walking. The study will investigate whether Q-angle is associated with specific plantar loading variables across different foot regions in active young adults.
Detailed description
This observational study is designed to investigate the association between Q-angle and plantar loading characteristics in physically active young adults. Q-angle is a commonly used measure of lower-extremity alignment, but its relationship with regional plantar loading during gait has not been fully clarified.
Participants will undergo bilateral Q-angle assessment under standardized conditions and dynamic pedobarographic evaluation during walking. Plantar pressure variables will be obtained for different foot regions, including the toes, forefoot, midfoot, hindfoot, and total foot. The primary objective is to determine whether Q-angle is associated with selected regional plantar loading variables. Secondary analyses will explore whether these associations differ according to sex and limb dominance.
Statistical analyses will be performed using linear mixed-effects models to account for within-subject dependence between bilateral measurements.This study focuses on the relationship between lower-extremity alignment and regional plantar loading patterns in physically active young adults.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Physically active young adults | – | Diagnostic Test: Q-angle and plantar pressure assessmentPhysically active young adults who underwent Q-angle measurement and plantar pressure assessment during walking. No therapeutic intervention was applied. |
Who may qualify
- Ages
- 18 to 27 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Physically active young adults aged 18 years and older who were able to walk independently and had no current lower-extremity injury, neurological disorder, or other condition affecting gait or plantar loading. Participants underwent Q-angle measurement and plantar pressure assessment during walking.
Key inclusion criteria (1 listed)
- being within the predefined young age range, (2) being physically active according to the IPAQ-SF based assessment, and (3) willingness to participate voluntarily.
Key exclusion criteria (1 listed)
- history of lower extremity injury within the previous 6 months, (2) previous lower extremity surgery, (3) known neurological or vestibular disorder affecting gait or balance, (4) current musculoskeletal pain in the spine or lower extremities during assessment, (5) diagnosed structural lower extremity deformity, and (6) inability to complete the assessment procedures independently.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Q-angle and plantar pressure assessmentParticipants underwent Q-angle measurement and plantar pressure assessment during walking for observational evaluation. No therapeutic or preventive intervention was applied. | Diagnostic test | Physically active young adults |
Primary outcome
Association between Q-angle and regional pedobarography outcomes
Time frame: At baseline
Regional plantar pressure, force, contact area, and contact time outcomes assessed in relation to Q-angle.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Mar 2026.
- Results publication: PubMed 25598843Dowling GJ, Murley GS, Munteanu SE, Smith MM, Neal BS, Griffiths IB, Barton CJ, Collins NJ. Dynamic foot function as a risk factor for lower limb overuse injury: a systematic review. J Foot Ankle Res. 2014 Dec 19;7(1):53. doi: 10.1186/s13047-014-0053-6. eCollection 2014.
- Results publication: PubMed 35789776Harvey HD, Game C, Walsh TP, Wearing SC, Platt SR. Are models of plantar heel pain suitable for competitive runners? A narrative review. J Orthop. 2022 Jun 21;33:9-14. doi: 10.1016/j.jor.2022.06.011. eCollection 2022 Sep-Oct.
- Results publication: PubMed 25451861Freedman BR, Brindle TJ, Sheehan FT. Re-evaluating the functional implications of the Q-angle and its relationship to in-vivo patellofemoral kinematics. Clin Biomech (Bristol). 2014 Dec;29(10):1139-45. doi: 10.1016/j.clinbiomech.2014.09.012. Epub 2014 Oct 7.
- Results publication: PubMed 37176736Hu Z, Zhang Y, Dong T, Dong M, Kim S, Kim Y. Gender Differences in Neuromuscular Control during the Preparation Phase of Single-Leg Landing Task in Badminton. J Clin Med. 2023 May 5;12(9):3296. doi: 10.3390/jcm12093296.
- Results publication: PubMed 21950470Lee OE, Braun TM. Permutation tests for random effects in linear mixed models. Biometrics. 2012 Jun;68(2):486-93. doi: 10.1111/j.1541-0420.2011.01675.x. Epub 2011 Sep 27.
- Results publication: PubMed 27293245Setia MS. Methodology Series Module 3: Cross-sectional Studies. Indian J Dermatol. 2016 May-Jun;61(3):261-4. doi: 10.4103/0019-5154.182410.
- Results publication: PubMed 32245235Cen X, Xu D, Baker JS, Gu Y. Association of Arch Stiffness with Plantar Impulse Distribution during Walking, Running, and Gait Termination. Int J Environ Res Public Health. 2020 Mar 21;17(6):2090. doi: 10.3390/ijerph17062090.
- Derived from this study: PubMed 42854518Akduman V, Karakoc ZB, Senocak E, Mete E, Acar G. Region-specific associations between Q-angle and plantar loading in physically active young adults. J Biomech. 2026 Oct 8;208:113611. doi: 10.1016/j.jbiomech.2026.113611. Online ahead of print.
- Individual participant dataSharing planned: Undecided. Individual participant data sharing has not yet been determined. Any future data sharing will depend on ethical approval, participant consent, institutional policies, and data de-identification requirements.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Veysel Akduman, PhD principal investigator
Marmara University
Veysel akduman, PhD principal investigator
Harran University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Q-angle and Plantar Loading Patterns, run by Harran University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Association between Q-angle and regional pedobarography outcomes (time frame: At baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07500597, which also lists 8 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Mar 2026.