StrokeNCT07502326
Functional Changes and Home Discharge After Inpatient Stroke Rehabilitation
An observational study of Stroke and Cerebrovascular Disease, run by SeongKi Min at 1 site in South Korea.
Trial summary
This retrospective observational study will evaluate whether changes in functional status during inpatient rehabilitation are associated with discharge destination in patients with stroke treated at a post-acute rehabilitation hospital. Read more about this study
- Who is it for?
- Ages 19 years and older
- Conditions the study is for
- Stroke, Cerebrovascular Disease
- What is being tested?
- Inpatient Rehabilitation
- How many people
- 119 participants
- Where
- 1 siteSouth Korea
- Study dates
- 1 Jan 2024to 31 Mar 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult patients with stroke who were admitted to the post-acute rehabilitation ward at Zenith Hospital and discharged between January 1, 2024 and March 31, 2025, with de-identified electronic medical record data available for integrated rehabilitation functional assessments at both admission and discharge.
Who may be able to join
- Patients with stroke who were admitted to and discharged from the convalescent rehabilitation ward at Zenith Hospital between January 1, 2024, and March 31, 2025
- Age 19 years or older
- Integrated rehabilitation functional assessment data available in the electronic medical record at both admission and discharge, including Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT)
Who cannot join
- Missing admission or discharge functional assessment data
- Patients with terminal illnesses that made rehabilitation treatment infeasible, such as advanced cancer or end-stage heart failure
- In-hospital death or transfer before discharge assessment, resulting in no discharge functional assessment data
- Insufficient electronic medical record data for the study analysis
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Association Between Changes in Integrated Rehabilitation Functional Assessment and Discharge Destination in Patients With Stroke in a Post-Acute Rehabilitation Hospital: A Retrospective EMR-Based Observational Study
This retrospective observational study will evaluate whether changes in functional status during inpatient rehabilitation are associated with discharge destination in patients with stroke treated at a post-acute rehabilitation hospital. The study will use de-identified electronic medical record data from adult patients with stroke who were admitted to Zenith Hospital and discharged between January 1, 2024 and March 31, 2025.
Integrated rehabilitation functional assessment data obtained at admission and discharge will be analyzed, including the Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT). The main objective is to determine whether changes in these measures during hospitalization are associated with discharge destination, defined as home discharge versus transfer to another institution.
A total of 119 eligible patients were included in the final analysis. Only existing de-identified EMR data will be used. No direct participant contact, additional data collection, or protocol-assigned intervention will occur. Findings from this study may provide evidence to support discharge planning and community reintegration strategies for patients with stroke receiving post-acute rehabilitation.
Read the detailed description
Stroke is a major cause of disability, and discharge destination after inpatient rehabilitation is an important clinical and social outcome. In post-acute rehabilitation settings, integrated functional assessments are routinely performed during hospitalization, but there is limited evidence on whether the magnitude of functional improvement between admission and discharge is associated with home discharge among patients with stroke in Korean rehabilitation hospitals. This study is designed to address that gap using de-identified electronic medical record data from a post-acute rehabilitation hospital.
The primary purpose of this study is to investigate the association between changes in integrated rehabilitation functional assessment scores during hospitalization and discharge destination in patients with stroke. Specifically, the study will evaluate whether changes in Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT) are associated with home discharge versus transfer to another institution.
This is a retrospective observational study conducted at Zenith Hospital, a post-acute rehabilitation hospital in the Republic of Korea. The study population will include adult patients with stroke who were admitted to the rehabilitation ward and discharged between January 1, 2024 and March 31, 2025. Eligible participants must have integrated rehabilitation functional assessment data recorded in the electronic medical record at both admission and discharge. Patients with missing admission or discharge functional assessment data, terminal illness preventing rehabilitation, in-hospital death, or insufficient EMR data for analysis will be excluded.
The main independent variables are changes in functional assessment scores between admission and discharge, including delta K-MBI, delta FAC, delta BBS, delta MMSE, and delta MFT. The primary outcome is discharge destination, categorized as home discharge or transfer to another institution. Covariates available in the EMR, such as age, sex, length of stay, and stroke type, will also be analyzed as potential confounders.
The study procedures are as follows: the hospital medical records team will identify potentially eligible patients according to the inclusion and exclusion criteria; all direct identifiers will be removed from the EMR data; a study-specific de-identified code will be assigned; and only de-identified data will be provided to the investigator for analysis. The investigator will calculate functional changes and perform statistical analyses to identify factors associated with discharge destination. There will be no participant contact, no prospective enrollment, no survey administration, and no intervention assigned as part of this study.
The study has been reviewed and approved by the Public Institutional Bioethics Committee No. 1 designated by the Ministry of Health and Welfare (Approval No. P01-202512-01-054). The findings are expected to provide practical evidence for discharge planning, patient stratification, and community reintegration support in post-acute stroke rehabilitation.
- Conditions
- Stroke, Cerebrovascular Disease
- Being tested
- Inpatient Rehabilitation
- Keywords
- Post-Acute Rehabilitation, Discharge Destination, Home Discharge, Electronic Medical Record, Functional Recovery, Korean Modified Barthel Index, Functional Ambulation Category, Berg Balance Scale, Mini-Mental State Examination, Manual Function Test
- Medical subject headings
- Stroke, Cerebrovascular Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Inpatient RehabilitationOther
Usual inpatient rehabilitation received during admission as part of routine clinical care. No intervention was assigned by the study protocol.
| Study group | Role | What they receive |
|---|---|---|
| Stroke Rehabilitation Cohort | Adult patients with stroke who received inpatient rehabilitation at Zenith Hospital and met the study eligibility criteria. Receives: Other: Inpatient Rehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Discharge Destination
Discharge destination assessed at discharge from inpatient rehabilitation, categorized as home discharge or transfer to another institution.
Measured: At discharge from inpatient rehabilitation
Secondary outcomes (5)
Change in Korean Modified Barthel Index (K-MBI) score
Change in Korean Modified Barthel Index score from admission to discharge. The Korean Modified Barthel Index is a measure of activities of daily living with scores ranging from 0 to 100, where higher scores indicate greater independence.
Measured: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Change in Functional Ambulation Category (FAC) score
Change in Functional Ambulation Category score from admission to discharge. The Functional Ambulation Category is a measure of walking ability with scores ranging from 0 to 5, where higher scores indicate better ambulation.
Measured: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Change in Berg Balance Scale (BBS) score
Change in Berg Balance Scale score from admission to discharge. The Berg Balance Scale assesses functional balance using 14 items scored from 0 to 4, with total scores ranging from 0 to 56; higher scores indicate better balance function.
Measured: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Change in Mini-Mental State Examination (MMSE) score
Change in Mini-Mental State Examination score from admission to discharge. The MMSE is a measure of cognitive function with scores ranging from 0 to 30, where higher scores indicate better cognitive status.
Measured: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Change in Manual Function Test (MFT) score
Change in Manual Function Test score from admission to discharge. The Manual Function Test is a measure of upper extremity motor function with scores ranging from 0 to 32, where higher scores indicate better upper extremity function.
Measured: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Mar 2026
- Study start1 Jan 2024
- Primary completion31 Mar 2025
- Study completion31 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 119 participants (actual)
Sponsor and investigators
- Lead sponsor
- SeongKi Min
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, SeongKi Min, Zenith Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07502326
- Sponsor's protocol ID
- P01-202512-01-054
- Status last verified
- Aug 2026
- First submitted
- 8 Mar 2026
- Last updated
- 17 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared because this retrospective study uses de-identified electronic medical record data collected at a single institution, and data sharing is restricted by institutional policy and ethics requirements to protect participant privacy and confidentiality.
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Association Between Changes in Integrated Rehabilitation Functional Assessment and Discharge Destination in Patients With Stroke in a Post-Acute Rehabilitation Hospital: A Retrospective EMR-Based Observational Study
- ClinicalTrials.gov ID
- NCT07502326
- Acronym / sponsor ID
- P01-202512-01-054
- Conditions
- Stroke, Cerebrovascular Disease
- Keywords
- Post-Acute Rehabilitation, Discharge Destination, Home Discharge, Electronic Medical Record, Functional Recovery, Korean Modified Barthel Index, Functional Ambulation Category, Berg Balance Scale
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 119 participants (actual)
- Lead sponsor
- SeongKi MinUniversity, hospital or other
- Study start
- 1 Jan 2024 (actual)
- Primary completion
- 31 Mar 2025 (actual)
- Study completion
- 31 Mar 2025 (actual)
- First posted
- 31 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This retrospective observational study will evaluate whether changes in functional status during inpatient rehabilitation are associated with discharge destination in patients with stroke treated at a post-acute rehabilitation hospital. The study will use de-identified electronic medical record data from adult patients with stroke who were admitted to Zenith Hospital and discharged between January 1, 2024 and March 31, 2025.
Integrated rehabilitation functional assessment data obtained at admission and discharge will be analyzed, including the Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT). The main objective is to determine whether changes in these measures during hospitalization are associated with discharge destination, defined as home discharge versus transfer to another institution.
A total of 119 eligible patients were included in the final analysis. Only existing de-identified EMR data will be used. No direct participant contact, additional data collection, or protocol-assigned intervention will occur. Findings from this study may provide evidence to support discharge planning and community reintegration strategies for patients with stroke receiving post-acute rehabilitation.
Detailed description
Stroke is a major cause of disability, and discharge destination after inpatient rehabilitation is an important clinical and social outcome. In post-acute rehabilitation settings, integrated functional assessments are routinely performed during hospitalization, but there is limited evidence on whether the magnitude of functional improvement between admission and discharge is associated with home discharge among patients with stroke in Korean rehabilitation hospitals. This study is designed to address that gap using de-identified electronic medical record data from a post-acute rehabilitation hospital.
The primary purpose of this study is to investigate the association between changes in integrated rehabilitation functional assessment scores during hospitalization and discharge destination in patients with stroke. Specifically, the study will evaluate whether changes in Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT) are associated with home discharge versus transfer to another institution.
This is a retrospective observational study conducted at Zenith Hospital, a post-acute rehabilitation hospital in the Republic of Korea. The study population will include adult patients with stroke who were admitted to the rehabilitation ward and discharged between January 1, 2024 and March 31, 2025. Eligible participants must have integrated rehabilitation functional assessment data recorded in the electronic medical record at both admission and discharge. Patients with missing admission or discharge functional assessment data, terminal illness preventing rehabilitation, in-hospital death, or insufficient EMR data for analysis will be excluded.
The main independent variables are changes in functional assessment scores between admission and discharge, including delta K-MBI, delta FAC, delta BBS, delta MMSE, and delta MFT. The primary outcome is discharge destination, categorized as home discharge or transfer to another institution. Covariates available in the EMR, such as age, sex, length of stay, and stroke type, will also be analyzed as potential confounders.
The study procedures are as follows: the hospital medical records team will identify potentially eligible patients according to the inclusion and exclusion criteria; all direct identifiers will be removed from the EMR data; a study-specific de-identified code will be assigned; and only de-identified data will be provided to the investigator for analysis. The investigator will calculate functional changes and perform statistical analyses to identify factors associated with discharge destination. There will be no participant contact, no prospective enrollment, no survey administration, and no intervention assigned as part of this study.
The study has been reviewed and approved by the Public Institutional Bioethics Committee No. 1 designated by the Ministry of Health and Welfare (Approval No. P01-202512-01-054). The findings are expected to provide practical evidence for discharge planning, patient stratification, and community reintegration support in post-acute stroke rehabilitation.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Stroke Rehabilitation Cohort | – | Other: Inpatient RehabilitationAdult patients with stroke who received inpatient rehabilitation at Zenith Hospital and met the study eligibility criteria. |
Who may qualify
- Ages
- 19 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adult patients with stroke who were admitted to the post-acute rehabilitation ward at Zenith Hospital and discharged between January 1, 2024 and March 31, 2025, with de-identified electronic medical record data available for integrated rehabilitation functional assessments at both admission and discharge.
Key inclusion criteria (3 listed)
- Patients with stroke who were admitted to and discharged from the convalescent rehabilitation ward at Zenith Hospital between January 1, 2024, and March 31, 2025
- Age 19 years or older
- Integrated rehabilitation functional assessment data available in the electronic medical record at both admission and discharge, including Korean Modified Barthel Index (K-MBI), Functional Ambulation Category (FAC), Berg Balance Scale (BBS), Mini-Mental State Examination (MMSE), and Manual Function Test (MFT)
Key exclusion criteria (4 listed)
- Missing admission or discharge functional assessment data
- Patients with terminal illnesses that made rehabilitation treatment infeasible, such as advanced cancer or end-stage heart failure
- In-hospital death or transfer before discharge assessment, resulting in no discharge functional assessment data
- Insufficient electronic medical record data for the study analysis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Inpatient RehabilitationUsual inpatient rehabilitation received during admission as part of routine clinical care. No intervention was assigned by the study protocol. | Other | Stroke Rehabilitation Cohort |
Primary outcome
Discharge Destination
Time frame: At discharge from inpatient rehabilitation
Discharge destination assessed at discharge from inpatient rehabilitation, categorized as home discharge or transfer to another institution.
5 secondary outcomes
Change in Korean Modified Barthel Index (K-MBI) score
Time frame: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Change in Functional Ambulation Category (FAC) score
Time frame: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Change in Berg Balance Scale (BBS) score
Time frame: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Change in Mini-Mental State Examination (MMSE) score
Time frame: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Change in Manual Function Test (MFT) score
Time frame: Within 3 days after admission and within 3 days before discharge from inpatient rehabilitation
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared because this retrospective study uses de-identified electronic medical record data collected at a single institution, and data sharing is restricted by institutional policy and ethics requirements to protect participant privacy and confidentiality.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Stroke and Cerebrovascular Disease, run by SeongKi Min at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Discharge Destination (time frame: At discharge from inpatient rehabilitation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2026.