Piriformis SyndromePIRI-REHABNCT07502573
Telerehabilitation vs. Home Exercise in Piriformis Syndrome: A Comparative Study
A study testing Home exercise programme and telerehabilitation in people with Piriformis Syndrome and Exercise Training, run by Hacettepe University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to compare the effects of asynchronous telerehabilitation and home exercise programs on pain, fear of pain, functionality, and performance in individuals with piriformis syndrome. Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- Piriformis Syndrome, Exercise Training, Telerehabilitation
- What is being tested?
- Home exercise programme and telerehabilitation
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 46 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Mar 2026to 30 May 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Be between the ages of 18 and 45,
- Be willing to participate in the study,
- Have been diagnosed with piriformis syndrome by a specialist doctor,
- Have positive Fair and Lasegue tests,
- Have pain between 3 and 9 on the Numerical Pain Scale,
Who cannot join
- Bilateral pain,
- Having a systemic disease,
- Recent injury to the lower extremity, having undergone surgery, having a pathology,
- Sacroiliac joint dysfunction, disc herniation, facet joint problem
- Having congenital problems,
- Having cognitive problems,
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Saglik Bilimleri University
Ankara, Kecioren, 06018
About this study
Official title: COMPARISON OF THE EFFECTS OF ASYNCHRONOUS TELEREHABILITATION AND HOME EXERCISE PROGRAM ON PAIN, PAIN FEAR, FUNCTIONALITY, AND PERFORMANCE IN INDIVIDUALS WITH PIRIFORMIS SYNDROME
The aim of this study is to compare the effects of asynchronous telerehabilitation and home exercise programs on pain, fear of pain, functionality, and performance in individuals with piriformis syndrome.
Read the detailed description
In this randomized controlled trial, performance has been determined as the primary outcome measure. Pain, functionality, and fear of pain have been determined as secondary outcome measures. A 6-week asynchronous telerehabilitation protocol is planned for patients with Piriformis Syndrome, with a home program serving as the control group. Informed consent forms will be obtained from participants. Participants will be enrolled at the Physical Therapy and Rehabilitation Home Exercise Program Clinic of Kocaeli City Hospital Physical Therapy Hospital and the study will commence after obtaining ethical committee approval. The Helsinki Principles will be adhered to for individuals included in the study.
- Conditions
- Piriformis Syndrome, Exercise Training, Telerehabilitation
- Being tested
- Home exercise programme, telerehabilitation
- Keywords
- telerehabilitation, exercise training, piriformis syndrome, pain, physical performance
- Medical subject headings
- Piriformis Muscle Syndrome, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Home exercise programmeBehavioural
Applications to be used for telerehabilitation: Musclewiki, YouTube (Medstar Health) may be used. Participants will be directed to exercise for 45 minutes, 3 days a week, via recorded videos sent to them. The difficulty level of the exercises is planned to increase every two weeks.
telerehabilitationBehavioural
Applications to be used for telerehabilitation: Musclewiki, YouTube (Medstar Health) may be used. Participants will be directed to exercise for 45 minutes, 3 days a week, via recorded videos sent to them. The difficulty level of the exercises is planned to increase every two weeks.
| Study group | Role | What they receive |
|---|---|---|
| physical performance | Active comparator | Participants evaluted with 5 times sit stand test Receives: Behavioral: Home exercise programme; Behavioral: telerehabilitation |
| pain | Active comparator | Pain levels of participants will evaluated Receives: Behavioral: Home exercise programme; Behavioral: telerehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Physical performance
The Timed Up and Go Test (TUG) measures the time it takes for an individual to stand up from a chair upon command, walk around a point 3 meters away, and return to sit in the chair. A time exceeding 15 seconds indicates a risk of falling.
Measured: before and after 8 week exercise programme
Secondary outcomes (1)
pain catastrophise
This is a questionnaire developed to measure how much people are driven to disaster in response to pain. The questionnaire lists 13 situations using a 5-point Likert scale (0-4) that describes different feelings and thoughts that may be related to pain. The total score can range from 0 to 52. It consists of 3 subfactors: helplessness, magnification, rumination. High scale scores are associated with more pain and more functional impairment.
Measured: before and after the 8 week exercise programme
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Mar 2026
- Study start1 Mar 2026
- Primary completion1 Sep 2026 (estimated)
- Study completion30 May 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Piriformis SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Stretching and nerve mobilization exercises will be performed before other exercises in telerehabilitation and home program groups. These exercises will be demonstrated to participants by the physical therapist in person during the first session.
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 46 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hacettepe University
- Sponsor type
- University, hospital or other
- Collaborators
- Kocaeli City Hospital, Saglik Bilimleri Universitesi
- Responsible party
- Principal investigator, Tezel Yıldırım Şahan, Saglik Bilimleri Universitesi
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07502573
- Sponsor's protocol ID
- 2026-333
- Acronym
- PIRI-REHAB
- Status last verified
- Apr 2026
- First submitted
- 25 Mar 2026
- Last updated
- 20 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Ozden F, Sari Z, Karaman ON, Aydogmus H. The effect of video exercise-based telerehabilitation on clinical outcomes, expectation, satisfaction, and motivation in patients with chronic low back pain. Ir J Med Sci. 2022 Jun;191(3):1229-1239. doi: 10.1007/s11845-021-02727-8. Epub 2021 Aug 6.
PubMed 34357527Onan D, Demirci E, Turhan E, Ulger O. Spinal stabilization exercises for transversus abdominis and lumbar multifidus thickness via telerehabilitation and face-to-face approaches in patients with nonspecific chronic neck pain: a randomized controlled trial. Turk J Med Sci. 2024 Jul 12;54(4):811-821. doi: 10.55730/1300-0144.5853. eCollection 2024.
PubMed 39295626Munoz-Tomas MT, Burillo-Lafuente M, Vicente-Parra A, Sanz-Rubio MC, Suarez-Serrano C, Marcen-Roman Y, Franco-Sierra MA. Telerehabilitation as a Therapeutic Exercise Tool versus Face-to-Face Physiotherapy: A Systematic Review. Int J Environ Res Public Health. 2023 Feb 28;20(5):4358. doi: 10.3390/ijerph20054358.
PubMed 36901375Ahmad Siraj S, Dadgal R. Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release. Cureus. 2022 Dec 26;14(12):e32952. doi: 10.7759/cureus.32952. eCollection 2022 Dec.
PubMed 36712711
Study at a glance
From the registry record, last updated by the sponsor on 20 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- COMPARISON OF THE EFFECTS OF ASYNCHRONOUS TELEREHABILITATION AND HOME EXERCISE PROGRAM ON PAIN, PAIN FEAR, FUNCTIONALITY, AND PERFORMANCE IN INDIVIDUALS WITH PIRIFORMIS SYNDROME
- ClinicalTrials.gov ID
- NCT07502573
- Acronym / sponsor ID
- PIRI-REHAB / 2026-333
- Conditions
- Piriformis Syndrome, Exercise Training, Telerehabilitation
- Keywords
- telerehabilitation, exercise training, piriformis syndrome, pain, physical performance
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 46 participants (estimated)
- Lead sponsor
- Hacettepe UniversityUniversity, hospital or other
- Collaborators
- Kocaeli City Hospital, Saglik Bilimleri Universitesi
- Study start
- 1 Mar 2026 (actual)
- Primary completion
- 1 Sep 2026 (estimated)
- Study completion
- 30 May 2027 (estimated)
- First posted
- 31 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to compare the effects of asynchronous telerehabilitation and home exercise programs on pain, fear of pain, functionality, and performance in individuals with piriformis syndrome.
Detailed description
In this randomized controlled trial, performance has been determined as the primary outcome measure. Pain, functionality, and fear of pain have been determined as secondary outcome measures. A 6-week asynchronous telerehabilitation protocol is planned for patients with Piriformis Syndrome, with a home program serving as the control group. Informed consent forms will be obtained from participants. Participants will be enrolled at the Physical Therapy and Rehabilitation Home Exercise Program Clinic of Kocaeli City Hospital Physical Therapy Hospital and the study will commence after obtaining ethical committee approval. The Helsinki Principles will be adhered to for individuals included in the study.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
- Model description
- Stretching and nerve mobilization exercises will be performed before other exercises in telerehabilitation and home program groups. These exercises will be demonstrated to participants by the physical therapist in person during the first session.
| Arm | Type | Receives |
|---|---|---|
| physical performance | Active comparator | Behavioral: Home exercise programme, Behavioral: telerehabilitationParticipants evaluted with 5 times sit stand test |
| pain | Active comparator | Behavioral: Home exercise programme, Behavioral: telerehabilitationPain levels of participants will evaluated |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Be between the ages of 18 and 45,
- Be willing to participate in the study,
- Have been diagnosed with piriformis syndrome by a specialist doctor,
- Have positive Fair and Lasegue tests,
- Have pain between 3 and 9 on the Numerical Pain Scale,
Key exclusion criteria (6 listed)
- Bilateral pain,
- Having a systemic disease,
- Recent injury to the lower extremity, having undergone surgery, having a pathology,
- Sacroiliac joint dysfunction, disc herniation, facet joint problem
- Having congenital problems,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Home exercise programmeApplications to be used for telerehabilitation: Musclewiki, YouTube (Medstar Health) may be used. Participants will be directed to exercise for 45 minutes, 3 days a week, via recorded videos sent to them. The difficulty level of the exercises is planned to increase every two weeks. | Behavioural | pain, physical performance |
| telerehabilitationApplications to be used for telerehabilitation: Musclewiki, YouTube (Medstar Health) may be used. Participants will be directed to exercise for 45 minutes, 3 days a week, via recorded videos sent to them. The difficulty level of the exercises is planned to increase every two weeks. | Behavioural | pain, physical performance |
Primary outcome
Physical performance
Time frame: before and after 8 week exercise programme
The Timed Up and Go Test (TUG) measures the time it takes for an individual to stand up from a chair upon command, walk around a point 3 meters away, and return to sit in the chair. A time exceeding 15 seconds indicates a risk of falling.
1 secondary outcome
pain catastrophise
Time frame: before and after the 8 week exercise programme
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Apr 2026.
- Background: PubMed 34357527Ozden F, Sari Z, Karaman ON, Aydogmus H. The effect of video exercise-based telerehabilitation on clinical outcomes, expectation, satisfaction, and motivation in patients with chronic low back pain. Ir J Med Sci. 2022 Jun;191(3):1229-1239. doi: 10.1007/s11845-021-02727-8. Epub 2021 Aug 6.
- Background: PubMed 39295626Onan D, Demirci E, Turhan E, Ulger O. Spinal stabilization exercises for transversus abdominis and lumbar multifidus thickness via telerehabilitation and face-to-face approaches in patients with nonspecific chronic neck pain: a randomized controlled trial. Turk J Med Sci. 2024 Jul 12;54(4):811-821. doi: 10.55730/1300-0144.5853. eCollection 2024.
- Background: PubMed 36901375Munoz-Tomas MT, Burillo-Lafuente M, Vicente-Parra A, Sanz-Rubio MC, Suarez-Serrano C, Marcen-Roman Y, Franco-Sierra MA. Telerehabilitation as a Therapeutic Exercise Tool versus Face-to-Face Physiotherapy: A Systematic Review. Int J Environ Res Public Health. 2023 Feb 28;20(5):4358. doi: 10.3390/ijerph20054358.
- Background: PubMed 36712711Ahmad Siraj S, Dadgal R. Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release. Cureus. 2022 Dec 26;14(12):e32952. doi: 10.7759/cureus.32952. eCollection 2022 Dec.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Home exercise programme and telerehabilitation in people with Piriformis Syndrome and Exercise Training, run by Hacettepe University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 20 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Physical performance (time frame: before and after 8 week exercise programme). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07502573, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Apr 2026.