ADHDADHD&meNCT07504107
ADHD&me: Targeting Self-esteem in Youth With ADHD
A study testing ADHD&me in people with ADHD, run by Universiteit Leiden at 1 site in Netherlands.
Trial summary
The goal of this clinical trial is to learn whether the ADHD\&me (ADHD\&ik) intervention can improve self-esteem in youth aged 16-25 years with Attention Deficit Hyperactivity Disorder (ADHD). Read more about this study
- Who is it for?
- Ages 16 to 25 years
- Conditions the study is for
- ADHD
- What is being tested?
- ADHD&me
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 110 participants
- Where
- 1 siteNetherlands
- Study dates
- 25 Mar 2026to 31 Mar 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 to 25 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- 16-25 years old.
- Official ADHD diagnosis, that is confirmed by research team using the clinical interview MINI-S.
- Low self-esteem, determined through a structured and multi-step procedure to minimize subjectivity:
- Referral by clinician. Clinicians from participating institutions identify potential participants. To ensure a uniform understanding of the study population and inclusion criteria, all clinicians receive specific training. The researcher(s) conduction the baseline assessment are also familiar with these training materials, so that the inclusion procedure is applied consistently.
- Telephone screening. Two items from the Rosenberg Self-Esteem Scale (RSES; Rosenberg, 1965) are administered ("At times I think I am no good at all" and "All in all, I am inclined to think I am a failure"). A score of 3 (agree) or 4 (strongly agree) on either of these items is considered indicative of low self-esteem.
- Baseline confirmation. During the baseline measurement, the full Rosenberg Self-Esteem Scale is administered. A cutoff score of < 15 is used as an objective reference point. This score is combined with a standardized clinical interview conducted by a trained researcher psychologist. At the ADHD section of the MINI-S at the baseline measurement, participants are asked by the researcher psychologist how their symptoms interfere with domains such as work, study, relationships, and self-esteem. If self-esteem is not mentioned, a follow-up question will be asked: "Many people with ADHD feel their symptoms affect their self-esteem, for example due to repeated negative feed- back, feeling like they are not good at things, or failing short. Do you recognize this in yourself"? Based on the participant's response, the trained researcher psychologist interviewer forms a professional, clinical impression of whether there are indicators of persistently low self-esteem (i.e.,insecurity, fear of failure, strong reactions to criticism, perfectionism, distress related to ADHD symptoms). This clinical assessment approach is based on examples provided by the Diagnostic Interview for ADHD in Adults (DIVA-2-NL; Kooij \& Francken, 2010). In all doubtful cases, the inclusion decision will be discussed in consensus meetings with the research team and supervisor, ensuring high inter-rater reliability.
- Pharmacological treatment for ADHD is allowed, but medication dose should be stabilized for a minimum of 4 weeks at baseline measurement (T0). Although changes in ADHD medication during the study are not preferred, they may occur in practice. Any such changed will be carefully documented.
Who cannot join
- Concurrent psychopathology that requires immediate attention (e.g., severe depression, suicidal thoughts/risk of suicide (as determined by the referring therapist and/or research team). Other comorbidity is allowed.
- Undergoing any concurrent psychological treatment during the study, including any form of therapy for ADHD (e.g., CBT for planning skills). Psychoeducation completed prior to the study entry is allowed, but not during the study.
- Low self-esteem that directly stems from a traumatic experience, which would indicate the need for trauma-specific treatment. This will be determined by the referring therapist. If someone in addition suffers from low self-esteem due to the ADHD symptoms, an appropriate timing of each treatment will be dis- cussed by the referring therapist and potential client.
- IQ < 80 assessed with two WAIS-IV subscales (Wechsler, 2008): Vocabulary and Block Design.
- Severe substance use (as determined by the referring therapist and/or research team).
- Confirmed Autism Spectrum Disorder (ASD) diagnosis. This also applies when the referring therapist indicates that an ASD diagnosis is very likely, even if it has not yet been established. Since ASD diagnostic procedures are time-consuming and fall outside the scope of this research project, formal ASD assessment will not be conducted within this study.
- Note. If included participants receive unforeseen supportive sessions outside the research setting, or if unforeseen medication changes occur during the study, these will be documented and considered during the analysis.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Jasmin Rahemenia contact
Netherlands1 site, 1 recruiting
- Recruiting
Psychologenpraktijk Kuin
Haarlem
Jasmin Rahemenia, MSc, +3171 5272727, j.rahemenia@fsw.leidenuniv.nl
About this study
Official title: ADHD&me: a Randomized Controlled Trial to Target Self-esteem in Youth With ADHD
The goal of this clinical trial is to learn whether the ADHD\&me (ADHD\&ik) intervention can improve self-esteem in youth aged 16-25 years with Attention Deficit Hyperactivity Disorder (ADHD). The ADHD\&me program is a cognitive behavioral therapy (CBT)-based intervention designed to help people with ADHD to develop a more positive view of themselves in their transition to adulthood.
The main questions it aims to answer are:
Read more
- Does the ADHD\&me intervention improve self-esteem in youth with ADHD, and are these effects maintained over time?
- Does the intervention also improve related outcomes, such as masking of ADHD-related behaviors and co-occurring mental health symptoms including anxiety, depression, and stress?
In this RCT, participants are assigned either to immediate treatment or to a waitlist control condition, with the latter receiving the intervention after an eight-week delay.
Participants will:
- Take part in seven individual therapy sessions according to the ADHD\&me intervention.
- Complete questionnaires about self-esteem, masking of ADHD-related behaviors, ADHD symptoms, and co-ccurring mental health symptoms at several time points.
- Complete short daily assessments (ecological momentary assessment) during one week at the start of the study and one week after the intervention or waitlist period to report momentary self-esteem, emotions, distress, and activities.
Read the detailed description
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental condition characterized by symptoms of inattention, impulsivity, and hyperactivity that may lead to impairments across multiple life domains. Although ADHD is often diagnosed in childhood, symptoms frequently persist into adulthood. Emerging adulthood is a developmental stage characterized by increasing independence and responsibilities related to education, work, and social relationships. For individuals with ADHD, these demands may intensify existing difficulties with attention regulation, organization, and time management. In addition to the core symptoms of ADHD, many individuals experience mental health difficulties such as anxiety, depression, and stress, which can further complicate daily functioning. These challenges highlight the importance of interventions that address not only ADHD symptoms but also broader psychological factors that influence functioning.
Low self-esteem is considered an important factor that may contribute to these difficulties. Throughout their lives, individuals with ADHD often encounter repeated experiences of failure, criticism, or negative feedback in academic, occupational, or social contexts. Over time, these experiences may lead to negative self-evaluations and reduced self-esteem. Low self-esteem may in turn exacerbate ADHD-related impairments and psychological distress, contributing to a negative cycle in which ADHD symptoms, stress, and comorbid mental health difficulties reinforce each other. Despite the importance of self-esteem for psychological functioning, many existing ADHD treatments primarily focus on reducing ADHD symptoms through skills training and may pay limited attention to self-esteem and masking. The aim of this study is therefore to evaluate whether the ADHD\&me intervention improves self-esteem in emerging adults with ADHD and whether these effects are associated with changes in related psychological outcomes.
The ADHD\&me (ADHD\&ik) intervention was developed to address this gap by specifically targeting self-esteem in emerging adults with ADHD. The intervention consists of seven individual therapy sessions and aims to strengthen self-esteem by addressing negative self-evaluations and masking behavior and by supporting participants in developing a more adaptive relationship with their ADHD. A pilot study was conducted, and the intervention protocol was refined through an iterative process based on its findings.
The effectiveness of the ADHD\&me intervention will be evaluated using a multicenter randomized controlled trial. Emerging adults with ADHD and low self-esteem will be randomly assigned in a 1:1 ratio to either (1) an immediate intervention group with two-month follow-up assessment or (2) a waitlist control condition receiving the intervention after an eight-week delay. Randomization will be performed using stratified block randomization based on ADHD medication use (yes/no), gender (male/female), and age group (16-20/21-25).
The primary outcome of the study is self-esteem. Secondary outcomes include masking of ADHD-related behaviors, ADHD symptoms, anxiety symptoms, depressive symptoms, perceived stress, executive functioning, rejection sensitivity, and quality of life. In addition to questionnaire assessments, ecological momentary assessment (EMA) will be used to examine fluctuations in self-esteem, emotions, and distress in daily life. Additional measures will assess treatment-related factors such as therapeutic alliance, client satisfaction, and treatment integrity to evaluate the quality of intervention delivery and therapists/participants' experiences.
- Conditions
- ADHD
- Being tested
- ADHD&me
- Keywords
- ADHD, Self-esteem, Masking, Comorbidity, Young adults, Youth, CBT, Intervention, RCT
- Medical subject headings
- Attention Deficit Disorder with Hyperactivity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ADHD&meBehavioural
Also called ADHD&ik
The ADHD\&me (ADHD\&ik) intervention is a cognitive behavioral therapy (CBT)-based program designed to improve self-esteem in emerging adults (aged 16-25 years) with ADHD and low self-esteem. The intervention consists of seven individual therapy sessions of approximately 45-60 minutes delivered by trained therapists. The program combines psychoeducation, cognitive and behavioral exercises to help participants understand the interaction between ADHD, stress, and self-beliefs. Core components include identifying negative self-beliefs and masking behaviours, strengthening positive self-representations through positive memories and personal strengths, and examining and modifying person-environment interactions. Sessions follow a structured workbook-based format and include exercises, goal setting, and between-session practice assignments to support the development of a more positive self-esteem.
| Study group | Role | What they receive |
|---|---|---|
| Intervention | Experimental | Participants receive the CBT-based ADHD\&me intervention immediately after randomization (7 weekly individual sessions) and have a follow-up assessment two months after treatment Receives: Behavioral: ADHD&me |
| Waitlist-control (delayed intervention) | Other | Participants are assigned to a waitlist and receive the intervention after an 8-week delay. Receives: Behavioral: ADHD&me |
What is being measured
The primary outcome is the main question the study is designed to answer.
Self-Esteem (Rosenberg Self-Esteem Scale; RSES)
Self-esteem will be assessed using the Rosenberg Self-Esteem Scale (RSES), a 10-item self-report questionnaire measuring global self-worth and positive and negative beliefs about the self. Items are rated on a four-point Likert scale, with higher scores indicating higher levels of self-esteem.
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Secondary outcomes (10)
Change in Masking of ADHD-Related Behavior (MAT-Q)
Masking of ADHD-related behavior will be assessed using the MAT-Q, measuring the extent to which individuals hide, compensate for, or suppress ADHD-related behavior in social, academic, or performance-related contexts. This questionnaire has yet to be validated.
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Depressive symptoms (Depression subscale of the DASS-42)
Depressive symptoms will be assessed using the depression subscale of the DASS-42 (14 items) scored on a 4-point scale; items are summed into a depression subscale score.
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Social anxiety symptoms (Liebowitz Social Anxiety Scale; LSAS)
Social anxiety symptoms will be assessed with the Dutch LSAS (24 items). Each item is scored twice (fear and avoidance) on a 4-point scale; scores are summed into a total score and subscale scores.
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Fear of negative evaluation (Brief Fear of Negative Evaluation; FNE)
Fear of negative evaluation will be assessed with the Dutch Brief FNE (12 items) scored on a 5-point scale; scores are summed into a total score. An additional item is included: "Do you believe you receive more/fewer negative evaluations compared to others?"
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Fear of positive evaluation (Fear of Positive Evaluation Scale; FPES)
Fear of positive evaluation will be assessed with the FPES (10 items) scored on a 0-9 scale; scores are summed into a total score. An additional item is included: "Do you believe you receive more/fewer positive evaluations compared to others?"
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Perceived stress (Perceived Stress Questionnaire; PSQ)
Perceived stress will be assessed using a translated Dutch version of the PSQ (30 items), scored on a 4-point scale reflecting how often it applied during the last month. Items are summed into a total score.
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Rejection sensitivity (Adult Rejection Sensitivity Questionnaire; ARSQ)
Rejection sensitivity will be assessed using a translated Dutch ARSQ (9 items) with ratings of rejection concern and rejection expectation. Total rejection sensitivity is calculated as the mean of item-level rejection sensitivity scores. An additional item is included: "Do you believe you are rejected more/less compared to others?"
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
ADHD symptoms (Self-report questionnaire on attention problems and hyperactivity; Kooij & Buitelaar, 1997)
ADHD symptoms will be assessed using the "Self-report questionnaire on attention problems and hyperactivity". The questionnaire includes 23 items scored on a 4-point scale. At baseline (T0) items are scored for adulthood and retrospectively for childhood; at T1 and T2 items are scored for adulthood only. Scores are summed into a total score.
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Executive functioning (Behavior Rating Inventory of Executive Function - Adult Version; BRIEF-A)
Executive functioning will be assessed with the Dutch BRIEF-A (75 items; 9 subscales). Items are scored on a 3-point scale. Scores are summarized into the Behavioral Regulation Index (BRI), Metacognition Index (MI), and Global Executive Composite (GEC), plus subscales.
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention/post-waitlist), and week 18 (two-month follow-up or post-intervention; T2).
Quality of life (Mental Health Quality of Life Questionnaire; MHQoL)
Quality of life will be assessed with the Dutch MHQoL (8 items). The first 7 items cover dimensions of quality of life (4 response levels); the final item assesses general psychological well-being on a 0-10 visual analogue scale.
Measured: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Mar 2026
- Study start25 Mar 2026
- Primary completion31 Mar 2028 (estimated)
- Study completion31 Mar 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ADHDStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to one of two conditions: an immediate intervention group or a waitlist control group. Participants in the immediate intervention group will start the ADHD\&me intervention directly after baseline assessment (T0). Participants in the waitlist control group will wait for eight weeks before starting the intervention. Both groups complete assessments at baseline (T0) and after the first study period (T1). Participants in the immediate intervention group then complete a follow-up assessment two months after the final intervention session (T2). Participants in the waitlist control group start the intervention after T1 and complete T2 after finishing the intervention. This delayed treatment design allows comparison between participants who receive the intervention and participants who are waiting to receive the intervention.
- Masking
- None (open label)
- Enrolment
- 110 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Universiteit Leiden
- Sponsor type
- University, hospital or other
- Collaborators
- Leids Universiteits Fonds
- Responsible party
- Principal investigator, Bianca Boyer, Universiteit Leiden
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07504107
- Sponsor's protocol ID
- NL-009591
- Acronym
- ADHD&me
- Status last verified
- May 2026
- First submitted
- 19 Mar 2026
- Last updated
- 14 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant data (IPD) underlying the results reported in publications may be shared after completion of the PhD project and after publication of the (primary) study results. Data sharing will only take place with permission of the principal investigator and in accordance with participant consent, applicable privacy regulations (GDPR), and institutional data management policies. Data will be shared in coded form for scientific research purposes only and may require a data sharing agreement. Requests for access to the data can be submitted to the principal investigator.
Study at a glance
From the registry record, last updated by the sponsor on 14 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- ADHD&me: a Randomized Controlled Trial to Target Self-esteem in Youth With ADHD
- ClinicalTrials.gov ID
- NCT07504107
- Acronym / sponsor ID
- ADHD&me / NL-009591
- Conditions
- ADHD
- Keywords
- ADHD, Self-esteem, Masking, Comorbidity, Young adults, Youth, CBT, Intervention
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 110 participants (estimated)
- Lead sponsor
- Universiteit LeidenUniversity, hospital or other
- Collaborators
- Leids Universiteits Fonds
- Study start
- 25 Mar 2026 (actual)
- Primary completion
- 31 Mar 2028 (estimated)
- Study completion
- 31 Mar 2028 (estimated)
- First posted
- 31 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn whether the ADHD\&me (ADHD\&ik) intervention can improve self-esteem in youth aged 16-25 years with Attention Deficit Hyperactivity Disorder (ADHD). The ADHD\&me program is a cognitive behavioral therapy (CBT)-based intervention designed to help people with ADHD to develop a more positive view of themselves in their transition to adulthood.
The main questions it aims to answer are:
- Does the ADHD\&me intervention improve self-esteem in youth with ADHD, and are these effects maintained over time?
- Does the intervention also improve related outcomes, such as masking of ADHD-related behaviors and co-occurring mental health symptoms including anxiety, depression, and stress?
In this RCT, participants are assigned either to immediate treatment or to a waitlist control condition, with the latter receiving the intervention after an eight-week delay.
Participants will:
- Take part in seven individual therapy sessions according to the ADHD\&me intervention.
- Complete questionnaires about self-esteem, masking of ADHD-related behaviors, ADHD symptoms, and co-ccurring mental health symptoms at several time points.
- Complete short daily assessments (ecological momentary assessment) during one week at the start of the study and one week after the intervention or waitlist period to report momentary self-esteem, emotions, distress, and activities.
Detailed description
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental condition characterized by symptoms of inattention, impulsivity, and hyperactivity that may lead to impairments across multiple life domains. Although ADHD is often diagnosed in childhood, symptoms frequently persist into adulthood. Emerging adulthood is a developmental stage characterized by increasing independence and responsibilities related to education, work, and social relationships. For individuals with ADHD, these demands may intensify existing difficulties with attention regulation, organization, and time management. In addition to the core symptoms of ADHD, many individuals experience mental health difficulties such as anxiety, depression, and stress, which can further complicate daily functioning. These challenges highlight the importance of interventions that address not only ADHD symptoms but also broader psychological factors that influence functioning.
Low self-esteem is considered an important factor that may contribute to these difficulties. Throughout their lives, individuals with ADHD often encounter repeated experiences of failure, criticism, or negative feedback in academic, occupational, or social contexts. Over time, these experiences may lead to negative self-evaluations and reduced self-esteem. Low self-esteem may in turn exacerbate ADHD-related impairments and psychological distress, contributing to a negative cycle in which ADHD symptoms, stress, and comorbid mental health difficulties reinforce each other. Despite the importance of self-esteem for psychological functioning, many existing ADHD treatments primarily focus on reducing ADHD symptoms through skills training and may pay limited attention to self-esteem and masking. The aim of this study is therefore to evaluate whether the ADHD\&me intervention improves self-esteem in emerging adults with ADHD and whether these effects are associated with changes in related psychological outcomes.
The ADHD\&me (ADHD\&ik) intervention was developed to address this gap by specifically targeting self-esteem in emerging adults with ADHD. The intervention consists of seven individual therapy sessions and aims to strengthen self-esteem by addressing negative self-evaluations and masking behavior and by supporting participants in developing a more adaptive relationship with their ADHD. A pilot study was conducted, and the intervention protocol was refined through an iterative process based on its findings.
The effectiveness of the ADHD\&me intervention will be evaluated using a multicenter randomized controlled trial. Emerging adults with ADHD and low self-esteem will be randomly assigned in a 1:1 ratio to either (1) an immediate intervention group with two-month follow-up assessment or (2) a waitlist control condition receiving the intervention after an eight-week delay. Randomization will be performed using stratified block randomization based on ADHD medication use (yes/no), gender (male/female), and age group (16-20/21-25).
The primary outcome of the study is self-esteem. Secondary outcomes include masking of ADHD-related behaviors, ADHD symptoms, anxiety symptoms, depressive symptoms, perceived stress, executive functioning, rejection sensitivity, and quality of life. In addition to questionnaire assessments, ecological momentary assessment (EMA) will be used to examine fluctuations in self-esteem, emotions, and distress in daily life. Additional measures will assess treatment-related factors such as therapeutic alliance, client satisfaction, and treatment integrity to evaluate the quality of intervention delivery and therapists/participants' experiences.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to one of two conditions: an immediate intervention group or a waitlist control group. Participants in the immediate intervention group will start the ADHD\&me intervention directly after baseline assessment (T0). Participants in the waitlist control group will wait for eight weeks before starting the intervention. Both groups complete assessments at baseline (T0) and after the first study period (T1). Participants in the immediate intervention group then complete a follow-up assessment two months after the final intervention session (T2). Participants in the waitlist control group start the intervention after T1 and complete T2 after finishing the intervention. This delayed treatment design allows comparison between participants who receive the intervention and participants who are waiting to receive the intervention.
| Arm | Type | Receives |
|---|---|---|
| Intervention | Experimental | Behavioral: ADHD&meParticipants receive the CBT-based ADHD\&me intervention immediately after randomization (7 weekly individual sessions) and have a follow-up assessment two months after treatment |
| Waitlist-control (delayed intervention) | Other | Behavioral: ADHD&meParticipants are assigned to a waitlist and receive the intervention after an 8-week delay. |
Who may qualify
- Ages
- 16 to 25 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (7 listed)
- 16-25 years old.
- Official ADHD diagnosis, that is confirmed by research team using the clinical interview MINI-S.
- Low self-esteem, determined through a structured and multi-step procedure to minimize subjectivity:
- Pharmacological treatment for ADHD is allowed, but medication dose should be stabilized for a minimum of 4 weeks at baseline measurement (T0). Although changes in ADHD medication during the study are not preferred, they may occur in practice. Any such changed will be carefully documented.
Key exclusion criteria (7 listed)
- Concurrent psychopathology that requires immediate attention (e.g., severe depression, suicidal thoughts/risk of suicide (as determined by the referring therapist and/or research team). Other comorbidity is allowed.
- Undergoing any concurrent psychological treatment during the study, including any form of therapy for ADHD (e.g., CBT for planning skills). Psychoeducation completed prior to the study entry is allowed, but not during the study.
- Low self-esteem that directly stems from a traumatic experience, which would indicate the need for trauma-specific treatment. This will be determined by the referring therapist. If someone in addition suffers from low self-esteem due to the ADHD symptoms, an appropriate timing of each treatment will be dis- cussed by the referring therapist and potential client.
- IQ < 80 assessed with two WAIS-IV subscales (Wechsler, 2008): Vocabulary and Block Design.
- Severe substance use (as determined by the referring therapist and/or research team).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ADHD&meAlso: ADHD&ikThe ADHD\&me (ADHD\&ik) intervention is a cognitive behavioral therapy (CBT)-based program designed to improve self-esteem in emerging adults (aged 16-25 years) with ADHD and low self-esteem. The intervention consists of seven individual therapy sessions of approximately 45-60 minutes delivered by trained therapists. The program combines psychoeducation, cognitive and behavioral exercises to help participants understand the interaction between ADHD, stress, and self-beliefs. Core components include identifying negative self-beliefs and masking behaviours, strengthening positive self-representations through positive memories and personal strengths, and examining and modifying person-environment interactions. Sessions follow a structured workbook-based format and include exercises, goal setting, and between-session practice assignments to support the development of a more positive self-esteem. | Behavioural | Intervention, Waitlist-control (delayed intervention) |
Primary outcome
Self-Esteem (Rosenberg Self-Esteem Scale; RSES)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Self-esteem will be assessed using the Rosenberg Self-Esteem Scale (RSES), a 10-item self-report questionnaire measuring global self-worth and positive and negative beliefs about the self. Items are rated on a four-point Likert scale, with higher scores indicating higher levels of self-esteem.
10 secondary outcomes
Change in Masking of ADHD-Related Behavior (MAT-Q)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Depressive symptoms (Depression subscale of the DASS-42)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Social anxiety symptoms (Liebowitz Social Anxiety Scale; LSAS)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Fear of negative evaluation (Brief Fear of Negative Evaluation; FNE)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Fear of positive evaluation (Fear of Positive Evaluation Scale; FPES)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Perceived stress (Perceived Stress Questionnaire; PSQ)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Rejection sensitivity (Adult Rejection Sensitivity Questionnaire; ARSQ)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
ADHD symptoms (Self-report questionnaire on attention problems and hyperactivity; Kooij & Buitelaar, 1997)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Executive functioning (Behavior Rating Inventory of Executive Function - Adult Version; BRIEF-A)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention/post-waitlist), and week 18 (two-month follow-up or post-intervention; T2).
Quality of life (Mental Health Quality of Life Questionnaire; MHQoL)
Time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 May 2026.
- Individual participant dataSharing planned: Yes. De-identified individual participant data (IPD) underlying the results reported in publications may be shared after completion of the PhD project and after publication of the (primary) study results. Data sharing will only take place with permission of the principal investigator and in accordance with participant consent, applicable privacy regulations (GDPR), and institutional data management policies. Data will be shared in coded form for scientific research purposes only and may require a data sharing agreement. Requests for access to the data can be submitted to the principal investigator.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Jasmin Rahemenia contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ADHD&me in people with ADHD, run by Universiteit Leiden at 1 site in Netherlands.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 14 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Bianca Boyer (+31 71 5272727, b.e.boyer@fsw.leidenuniv.nl), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Self-Esteem (Rosenberg Self-Esteem Scale; RSES) (time frame: Week 0 (T0; baseline), week 9 (T1; post-intervention or post-waitlist), and week 18 (T2; two-month follow-up or post-intervention.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 May 2026.