Cervical Radicular PainNCT07506200
Neuromuscular Re-education on Pain, ROM and Disability in Cervical Radiculopathy
A study testing Neuromuscular Re education and Conventional Physical Therapy in people with Cervical Radicular Pain, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study explores the effectiveness of Neuromuscular Re-education compared to conventional therapies in managing pain, range of motion, and disability in patients with Cervical Radiculopathy Read more about this study
- Who is it for?
- Ages 30 to 50 years
- Conditions the study is for
- Cervical Radicular Pain
- What is being tested?
- Neuromuscular Re education and Conventional Physical Therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Mar 2026to 15 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Participants of Age between 30 and 50 years old.
- Participants of both gender included.
- Participants having Unilateral upper extremity pain, paresthesia, or numbness
- Participants with Four positive findings required:
- Positive Spurling's test
- Positive distraction test
Show all 10Show fewer
- Positive upper limb tension test
- Ipsilateral cervical rotation less than 60 degrees
- Participants must have experienced pain for at least 3 months.
- Participants must have a pain score of 4 to 6 on the 0-10 scale
Who cannot join
- Participants having prior cervical spine surgery.
- Participants with Cervical vertebral fracture
- Participants with severe osteoporosis, rheumatic disease, shoulder disease, or infection will be excluded.
- Participants with vertebro-basilar artery insufficiency and diabetic neuropathy
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
National hospital sialkot
Sialkot, Punjab Province, 54500
Javeria Ghazal, MS, 03335154664, javeria.ghazal@riphah.edu.pk
Sofia Rehman, MS
About this study
Official title: Effects of Neuromuscular Re-education on Pain, Range of Motion and Disability in Patients With Cervical Radiculopathy
This study explores the effectiveness of Neuromuscular Re-education compared to conventional therapies in managing pain, range of motion, and disability in patients with Cervical Radiculopathy
Read the detailed description
The study identifies a gap in the current literature surrounding the effectiveness of neuromuscular re-education interventions in targeting pain reduction, disability improvement, and enhancement of range of motion for CR patients. Previous studies emphasize conventional methods, such as proprioceptive neuromuscular facilitation and manual therapy, with a general focus on motor control and postural re-education. However, the precise benefits of structured NMR exercises tailored to CR symptoms, particularly targeting proprioceptive training and functional task simulation, are less explored, especially compared to traditional interventions like heat/cold application or general strengthening
- Conditions
- Cervical Radicular Pain
- Being tested
- Neuromuscular Re education, Conventional Physical Therapy
- Keywords
- Cervical Radiculopathy, Neuromuscular Re-education, Range of Motion, Pain Management
- Medical subject headings
- Radiculopathy, Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Neuromuscular Re educationOther
- Postural training and functional task simulation(chin tuck, Shoulder blade squeeze, reaching, carrying, lifting tasks) Proprioceptive tasks( single leg stance with head movement), deep cervical strengthening.
3 sessions per week, 30 minutes per session (10 mint each component),10 repetition per set, 2 set, 10 second Resting interval Resting period: 1 mint to next exercise
Conventional Physical TherapyOther
- TENS and hot pack for 10 to 15 minutes
- Manual therapy techniques (e.g., mobilizations grade II). 5 to 10 repetition
- Cervical isometric exercises 10 reps
- General education on posture and ergonomics guidelines
- Frequency: 3 sessions per week
- Duration: 50 minutes per session, 10 mint each component
- Repetition: 10 repetition per set, 2 set , 10 second resting interval
- Resting period: 1 mint to next exercise
| Study group | Role | What they receive |
|---|---|---|
| Neuromuscular Re-education Group | Experimental | postural training exercises, proprioceptive tasks, Dynamic control exercises, eye-head coordination tasks Receives: Other: Neuromuscular Re education |
| Conventional Physical Therapy | Active comparator | Electrotherapy, Manual Therapy Techniques Receives: Other: Conventional Physical Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Goniometer
A goniometer is used to measure cervical range of motion (ROM) by aligning its fulcrum over a bony landmark (like the C7 vertebrae or external auditory meatus) and its arms with other bony landmarks (such as the nose, acromion, or sternal notch) to measure the angle of movement in degrees.
Measured: 8th Week
NDI (Neck Disability Index)
The NDI is a 10-item questionnaire that assesses how neck pain affects daily activities(28). The Neck Disability Index (NDI) measures neck-specific disability through a 10-item questionnaire assessing pain and daily activities like personal care, lifting, and concentration. Scores range from 0-50 (or 0-100%), with higher scores indicating greater disability
Measured: 8th week
Numeric Pain Rate Scale
The Numerical Pain Rating Scale (NPRS) has been used to assess the level of pain patients experience. It can be used to assess pain either verbally or through a self completion questionnaires. Patients are asked to circle a number on a scale that best describes the pain the experience. Patients are asked to recall from the pain scale from 0 to 10. 0 equals No pain, 1-3 equals Mild pain, 4-6 equals Moderate pain, 7-9 equals Severe pain, and 10 equals Very Severe pain. NPRS shows strong test-retest score even in illiterate and literate patients
Measured: 8th week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Apr 2026
- Study start1 Mar 2026
- Primary completion16 Jun 2026 (estimated)
- Study completion15 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cervical Radicular PainStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 52 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Javeria Ghazal, MS, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07506200
- Sponsor's protocol ID
- REC/RCR & AHS/24/0298
- Status last verified
- Jun 2026
- First submitted
- 23 Feb 2026
- Last updated
- 10 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 10 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Neuromuscular Re-education on Pain, Range of Motion and Disability in Patients With Cervical Radiculopathy
- ClinicalTrials.gov ID
- NCT07506200
- Acronym / sponsor ID
- REC/RCR & AHS/24/0298
- Conditions
- Cervical Radicular Pain
- Keywords
- Cervical Radiculopathy, Neuromuscular Re-education, Range of Motion, Pain Management
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Mar 2026 (actual)
- Primary completion
- 16 Jun 2026 (estimated)
- Study completion
- 15 Jul 2026 (estimated)
- First posted
- 1 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study explores the effectiveness of Neuromuscular Re-education compared to conventional therapies in managing pain, range of motion, and disability in patients with Cervical Radiculopathy
Detailed description
The study identifies a gap in the current literature surrounding the effectiveness of neuromuscular re-education interventions in targeting pain reduction, disability improvement, and enhancement of range of motion for CR patients. Previous studies emphasize conventional methods, such as proprioceptive neuromuscular facilitation and manual therapy, with a general focus on motor control and postural re-education. However, the precise benefits of structured NMR exercises tailored to CR symptoms, particularly targeting proprioceptive training and functional task simulation, are less explored, especially compared to traditional interventions like heat/cold application or general strengthening
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Neuromuscular Re-education Group | Experimental | Other: Neuromuscular Re educationpostural training exercises, proprioceptive tasks, Dynamic control exercises, eye-head coordination tasks |
| Conventional Physical Therapy | Active comparator | Other: Conventional Physical TherapyElectrotherapy, Manual Therapy Techniques |
Who may qualify
- Ages
- 30 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (10 listed)
- Participants of Age between 30 and 50 years old.
- Participants of both gender included.
- Participants having Unilateral upper extremity pain, paresthesia, or numbness
- Participants with Four positive findings required:
- Positive Spurling's test
Key exclusion criteria (4 listed)
- Participants having prior cervical spine surgery.
- Participants with Cervical vertebral fracture
- Participants with severe osteoporosis, rheumatic disease, shoulder disease, or infection will be excluded.
- Participants with vertebro-basilar artery insufficiency and diabetic neuropathy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Neuromuscular Re educationA. Postural training and functional task simulation(chin tuck, Shoulder blade squeeze, reaching, carrying, lifting tasks) Proprioceptive tasks( single leg stance with head movement), deep cervical strengthening. 3 sessions per week, 30 minutes per session (10 mint each component),10 repetition per set, 2 set, 10 second Resting interval Resting period: 1 mint to next exercise | Other | Neuromuscular Re-education Group |
| Conventional Physical Therapy* TENS and hot pack for 10 to 15 minutes * Manual therapy techniques (e.g., mobilizations grade II). 5 to 10 repetition * Cervical isometric exercises 10 reps * General education on posture and ergonomics guidelines * Frequency: 3 sessions per week * Duration: 50 minutes per session, 10 mint each component * Repetition: 10 repetition per set, 2 set , 10 second resting interval * Resting period: 1 mint to next exercise | Other | Conventional Physical Therapy |
Primary outcome
Goniometer
Time frame: 8th Week
A goniometer is used to measure cervical range of motion (ROM) by aligning its fulcrum over a bony landmark (like the C7 vertebrae or external auditory meatus) and its arms with other bony landmarks (such as the nose, acromion, or sternal notch) to measure the angle of movement in degrees.
NDI (Neck Disability Index)
Time frame: 8th week
The NDI is a 10-item questionnaire that assesses how neck pain affects daily activities(28). The Neck Disability Index (NDI) measures neck-specific disability through a 10-item questionnaire assessing pain and daily activities like personal care, lifting, and concentration. Scores range from 0-50 (or 0-100%), with higher scores indicating greater disability
Numeric Pain Rate Scale
Time frame: 8th week
The Numerical Pain Rating Scale (NPRS) has been used to assess the level of pain patients experience. It can be used to assess pain either verbally or through a self completion questionnaires. Patients are asked to circle a number on a scale that best describes the pain the experience. Patients are asked to recall from the pain scale from 0 to 10. 0 equals No pain, 1-3 equals Mild pain, 4-6 equals Moderate pain, 7-9 equals Severe pain, and 10 equals Very Severe pain. NPRS shows strong test-retest score even in illiterate and literate patients
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Javeria Ghazal, MS principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Neuromuscular Re education and Conventional Physical Therapy in people with Cervical Radicular Pain, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 10 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 10 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Munaab Khan, PhD (+923367993611, muneeb.khan@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Goniometer (time frame: 8th Week). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Jun 2026; AzTrials last refreshed its copy on 7 Nov 2026.