Type 2 DiabetesNCT07506278

Results Of Vivifrail Exercise In Older Type 2 Diabetic Patients With Fraity Syndrome

A study testing Vivifrail Exercise Programme Training in people with Type 2 Diabetes and Fraity Syndrome, run by National Geriatric Hospital at 1 site in Vietnam.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

Search all trials

Trial summary

Who is it for?: Ages 60 to 80 years
Conditions the study is for: Type 2 Diabetes, Fraity Syndrome, Exercise Intervention
What is being tested?: Vivifrail Exercise Programme Training
Type of treatment: Lifestyle or therapy programme
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 80 participants
Where: 1 siteVietnam
Study dates: 13 Sep 2024to 30 Jan 2026
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 60 to 80 years
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Type 2 diabetic patients diagnosed using American Diabetes Association 2022 criteria
HbA1c ≥ 6.5 and ≤ 9.0%
Frailty diagnosed using criteria from the The Fried frailty phenotype (FP)
Age ≥ 60 and ≤ 80

Who cannot join

Acute diabetic complications
Patients are in the acute phase of musculoskeletal disorders: acute gout, progressing low-grade arthritis, acute joint pain due to joint degeneration, sciatic pain, and infectious arthritis.
Patients suffer from conditions significantly affecting cognition and mobility: sequelae of stroke (with weakness, limb paralysis), muscular weakness, limb disabilities, severe heart failure, severe cognitive decline, and psychiatric disorders.
Patients have been bedridden due to illness for more than 1 month within the past 3 months up to the recruitment time.

Trial locations and contacts

1 site in 1 country.

Vietnam1 site

Phu Tho Province General Hospital
Viet Tri, Phu Tho, 35100

Other trials in Vietnam

About this study

Official title: Evaluating The Effect Of Fraity Intervention In Older Adults With Typ 2 Diabetes Using Exercise

A randomized controlled clinical trial that will test how physical exercise will impact outcomes of functional ability, cognitive function and quality of life in older patients with type 2 diabetes who have been diagnosed as Fraity syndrome. The intervention will be 6 months in duration with approximately 72 sessions of exercises. Outcome measures will be collected at baseline, 3 months and 6 months.

Read the detailed description

Fraity syndrome, prevalent among geriatric populations, is associated with higher susceptibility to falls, comorbidities, and mortality. Multidomain interventions have been shown to be effective in improving quality of life and delaying progression of functional impairment or disability in older adults. Specially, VIVIFRAIL was developed by world experts in the field of physical exercise and frailty, and is considered an important step towards the novel era of precise prescription of physical activity. Nevertheless, the effect of physical exercise as a systematic, structured and repetitive type of physical activity, in the reduction of risk of cognitive decline in the elderly, is not very clear.

Conditions: Type 2 Diabetes, Fraity Syndrome, Exercise Intervention
Being tested: Vivifrail Exercise Programme Training
Keywords: Type 2 Diabetes, Fraity syndrome, Exercise intervention, Vivifrail exercise programme, Fall Risk
Medical subject headings: Diabetes Mellitus, Type 2

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Vivifrail Exercise Programme TrainingBehavioural
Vivifrail exercise programme includes face-to-face education on Multi-component Physical training:
A Program for patients with moderate limitation with EXERCISE WHEEL include 7 exercises for 1 course. During the first 8 weeks, the patient exercises 3 times/week with a level of exertion according to Borg's category-ratio 10 (CR10) scale of 4-5 points. For the next 8 weeks, the patient exercises 3 times/week with Borg's CR10 exertion level of 6-7 points. In the last 8 weeks, the patient exercises 3 times/week with Borg's CR10 exertion level of 8-9 points.
The six-month intervention involves twenty-four weekly calls, with a focus on building rapport (e.g. providing feedback on the baseline assessment); education reinforcement on resistance training; and skill-building (e.g. self-monitoring and resistance training diary). The emphasis is on helping participants to gain the knowledge and skills necessary to achieve targeted intensity. Every 4 weeks, all patients are re-visite

Study groups in NCT07506278
Study group	Role	What they receive
Intervention group	Experimental	The intervention group receives supervised Vivifrail exercise programme training instructions: - Vivifrail exercise programme aims to increase muscle strength of the upper and lower limbs. Training duration 6 months, frequency 3 times/week, intensity gradually increases. Receives: Behavioral: Vivifrail Exercise Programme Training
Control group	No intervention	The control group receives the baseline treatment for diabetes: - Recommendations according to American Diabetes Association guidelines which include instructions to follow the diet and exercises as recommended for older type 2 diabetic patients (education about treatment measures such as diet and exercise) and provide basic information on flexibility training and balance training.

What is being measured

The primary outcome is the main question the study is designed to answer.

Physical performance 1 - Handgrip strength
Handgrip strength is assessed using a hand dynamometer named Jamar Hydraulic Hand Dynamometer: the higher number the better outcome.
Measured: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
Physical performance 2 - Gait speed
4-metre gait speed test (the shorter time the better outcome)
Measured: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
Physical performance 3 - Short Physical Performance Battery (SPPB)
The Short Physical Performance Battery developed by the National Institute on Aging: scores ranging from 0 (worst) to 12 (best)
Measured: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)

Secondary outcomes (5)

Nutritional status
Nutritional status is assessed using the Mini Nutritional Assessment Short-Form (MNA-SF): scores ranging from 0 (worst) to 14 (best)
Measured: Prior to the start of intervention,3 months and 6 months (completion of the intervention)
Activities of Daily Living (ADLs)
Katz Index of Independence in Activities of Daily Living (scores range from 0-worst to 6-best)
Measured: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
The Mini-Cog Score
The Mini-Cog Score uses a three-item recall for memory and intuitive clock-drawing test to screen a dementia (scores range from 0-worst to 5-best)
Measured: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
21-item Fall Risk Index questionnaire
The 21-item Fall Risk Index (FRI-21) has been used to detect elderly persons at risk for falls: scores ranging from 0 (best) to 21 (worst)
Measured: Prior to the start of intervention,3 months and 6 months (completion of the intervention)
Instrumental Activities of Daily Living (IADLs)
Lawton Instrumental Activities of Daily Living Scale (scores range from 0-low function \& dependent to 8-high function \& independent for women, and 0-worst to 5-best for men)
Measured: First visit, 3 months, 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

13 Sep 202430 Jan 2026

First posted1 Apr 2026
Study start13 Sep 2024
Primary completion28 Jul 2025
Study completion30 Jan 2026

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (24)Papers the sponsor has linked to this study.
Other trials for Type 2 DiabetesStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Enrolment: 80 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07506278
Sponsor's protocol ID: Organization's Unique Protocol
Status last verified: Mar 2026
First submitted: 23 Mar 2026
Last updated: 1 Apr 2026
Results posted: No
Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No

Publications

Topolski TD, LoGerfo J, Patrick DL, Williams B, Walwick J, Patrick MB. The Rapid Assessment of Physical Activity (RAPA) among older adults. Prev Chronic Dis. 2006 Oct;3(4):A118. Epub 2006 Sep 15.
PubMed 16978493
Buyukavci R, Akturk S, Evren B, Ersoy Y. Impacts of combined osteopenia/osteoporosis and sarcopenia on balance and quality of life in older adults. North Clin Istanb. 2020 Oct 1;7(6):585-590. doi: 10.14744/nci.2020.28003. eCollection 2020.
PubMed 33381698
Zhang XL, Zhang Z, Zhu YX, Tao J, Zhang Y, Wang YY, Ke YY, Ren CX, Xu J, Zhang XY. Comparison of the efficacy of Nutritional Risk Screening 2002 and Mini Nutritional Assessment Short Form in recognizing sarcopenia and predicting its mortality. Eur J Clin Nutr. 2020 Jul;74(7):1029-1037. doi: 10.1038/s41430-020-0621-8. Epub 2020 Apr 9.
PubMed 32273572
Beltz S, Gloystein S, Litschko T, Laag S, van den Berg N. Multivariate analysis of independent determinants of ADL/IADL and quality of life in the elderly. BMC Geriatr. 2022 Nov 23;22(1):894. doi: 10.1186/s12877-022-03621-3.
PubMed 36418975
Nguyen TTH, Vu HTT, Nguyen TN, Dao HT, Nguyen TX, Nguyen HTT, Dang AK, Nguyen AT, Pham T, Vu GT, Tran BX, Latkin CA, Ho CS, Ho RC. Assessment of nutritional status in older diabetic outpatients and related factors in Hanoi, Vietnam. J Multidiscip Healthc. 2019 Jul 30;12:601-606. doi: 10.2147/JMDH.S194155. eCollection 2019.
PubMed 31534342
Sanchez-Sanchez JL, Udina C, Medina-Rincon A, Esbri-Victor M, Bartolome-Martin I, Moral-Cuesta D, Marin-Epelde I, Ramon-Espinoza F, Latorre MS, Idoate F, Goni-Sarries A, Martinez-Martinez B, Bonet RE, Librero J, Casas-Herrero A. Effect of a multicomponent exercise program and cognitive stimulation (VIVIFRAIL-COGN) on falls in frail community older persons with high risk of falls: study protocol for a randomized multicenter control trial. BMC Geriatr. 2022 Jul 23;22(1):612. doi: 10.1186/s12877-022-03214-0.
PubMed 35870875
Tamura Y, Omura T, Toyoshima K, Araki A. Nutrition Management in Older Adults with Diabetes: A Review on the Importance of Shifting Prevention Strategies from Metabolic Syndrome to Frailty. Nutrients. 2020 Nov 1;12(11):3367. doi: 10.3390/nu12113367.
PubMed 33139628
Lopez-Garcia E, Hagan KA, Fung TT, Hu FB, Rodriguez-Artalejo F. Mediterranean diet and risk of frailty syndrome among women with type 2 diabetes. Am J Clin Nutr. 2018 May 1;107(5):763-771. doi: 10.1093/ajcn/nqy026.
PubMed 29722845
Gobl C, Tura A. Focus on Nutritional Aspects of Sarcopenia in Diabetes: Current Evidence and Remarks for Future Research. Nutrients. 2022 Jan 13;14(2):312. doi: 10.3390/nu14020312.
PubMed 35057493
O'Donovan M, Sezgin D, O'Caoimh R, Liew A. The relationship between frailty and diabetes: An investigation of self-rated health, depression symptoms and quality of life in the Study of Health Aging and Retirement in Europe. Arch Gerontol Geriatr. 2021 Sep-Oct;96:104448. doi: 10.1016/j.archger.2021.104448. Epub 2021 May 29.
PubMed 34144317
Sinclair AJ, Abdelhafiz A, Dunning T, Izquierdo M, Rodriguez Manas L, Bourdel-Marchasson I, Morley JE, Munshi M, Woo J, Vellas B. An International Position Statement on the Management of Frailty in Diabetes Mellitus: Summary of Recommendations 2017. J Frailty Aging. 2018;7(1):10-20. doi: 10.14283/jfa.2017.39.
PubMed 29412437
Hanlon P, Faure I, Corcoran N, Butterly E, Lewsey J, McAllister D, Mair FS. Frailty measurement, prevalence, incidence, and clinical implications in people with diabetes: a systematic review and study-level meta-analysis. Lancet Healthy Longev. 2020 Dec;1(3):e106-e116. doi: 10.1016/S2666-7568(20)30014-3.
PubMed 33313578
Aguayo GA, Hulman A, Vaillant MT, Donneau AF, Schritz A, Stranges S, Malisoux L, Huiart L, Guillaume M, Sabia S, Witte DR. Prospective Association Among Diabetes Diagnosis, HbA1c, Glycemia, and Frailty Trajectories in an Elderly Population. Diabetes Care. 2019 Oct;42(10):1903-1911. doi: 10.2337/dc19-0497. Epub 2019 Aug 26.
PubMed 31451533
Cheng G, Huang C, Deng H, Wang H. Diabetes as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies. Intern Med J. 2012 May;42(5):484-91. doi: 10.1111/j.1445-5994.2012.02758.x.
PubMed 22372522
Aguayo GA, Fagherazzi G. Intricate relationships between frailty and diabetes: where do we go from here? Lancet Healthy Longev. 2020 Dec;1(3):e92-e93. doi: 10.1016/S2666-7568(20)30019-2. Epub 2020 Nov 19. No abstract available.
PubMed 36094190

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

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Study at a glance

From the registry record, last updated by the sponsor on 1 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Evaluating The Effect Of Fraity Intervention In Older Adults With Typ 2 Diabetes Using Exercise
ClinicalTrials.gov ID: NCT07506278
Acronym / sponsor ID: Organization's Unique Protocol
Conditions: Type 2 Diabetes, Fraity Syndrome, Exercise Intervention
Keywords: Type 2 Diabetes, Fraity syndrome, Exercise intervention, Vivifrail exercise programme, Fall Risk
Study type: Interventional
Recruitment status: Completed
Enrolment: 80 participants (actual)
Lead sponsor: National Geriatric HospitalOther government
Study start: 13 Sep 2024 (actual)
Primary completion: 28 Jul 2025 (actual)
Study completion: 30 Jan 2026 (actual)
First posted: 1 Apr 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Number of arms: 2

Arm	Type	Receives
Intervention group	Experimental	Behavioral: Vivifrail Exercise Programme TrainingThe intervention group receives supervised Vivifrail exercise programme training instructions: - Vivifrail exercise programme aims to increase muscle strength of the upper and lower limbs. Training duration 6 months, frequency 3 times/week, intensity gradually increases.
Control group	No intervention	–The control group receives the baseline treatment for diabetes: - Recommendations according to American Diabetes Association guidelines which include instructions to follow the diet and exercises as recommended for older type 2 diabetic patients (education about treatment measures such as diet and exercise) and provide basic information on flexibility training and balance training.

Who may qualify

Ages: 60 to 80 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult, Older adult

Key inclusion criteria (4 listed)

Type 2 diabetic patients diagnosed using American Diabetes Association 2022 criteria
HbA1c ≥ 6.5 and ≤ 9.0%
Frailty diagnosed using criteria from the The Fried frailty phenotype (FP)
Age ≥ 60 and ≤ 80

Key exclusion criteria (4 listed)

Acute diabetic complications
Patients are in the acute phase of musculoskeletal disorders: acute gout, progressing low-grade arthritis, acute joint pain due to joint degeneration, sciatic pain, and infectious arthritis.
Patients suffer from conditions significantly affecting cognition and mobility: sequelae of stroke (with weakness, limb paralysis), muscular weakness, limb disabilities, severe heart failure, severe cognitive decline, and psychiatric disorders.
Patients have been bedridden due to illness for more than 1 month within the past 3 months up to the recruitment time.

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Vivifrail Exercise Programme TrainingVivifrail exercise programme includes face-to-face education on Multi-component Physical training: A Program for patients with moderate limitation with EXERCISE WHEEL include 7 exercises for 1 course. During the first 8 weeks, the patient exercises 3 times/week with a level of exertion according to Borg's category-ratio 10 (CR10) scale of 4-5 points. For the next 8 weeks, the patient exercises 3 times/week with Borg's CR10 exertion level of 6-7 points. In the last 8 weeks, the patient exercises 3 times/week with Borg's CR10 exertion level of 8-9 points. The six-month intervention involves twenty-four weekly calls, with a focus on building rapport (e.g. providing feedback on the baseline assessment); education reinforcement on resistance training; and skill-building (e.g. self-monitoring and resistance training diary). The emphasis is on helping participants to gain the knowledge and skills necessary to achieve targeted intensity. Every 4 weeks, all patients are re-visite	Behavioural	Intervention group

Primary outcome

Physical performance 1 - Handgrip strength
Time frame: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
Handgrip strength is assessed using a hand dynamometer named Jamar Hydraulic Hand Dynamometer: the higher number the better outcome.
Physical performance 2 - Gait speed
Time frame: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
4-metre gait speed test (the shorter time the better outcome)
Physical performance 3 - Short Physical Performance Battery (SPPB)
Time frame: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
The Short Physical Performance Battery developed by the National Institute on Aging: scores ranging from 0 (worst) to 12 (best)

5 secondary outcomes

Nutritional status
Time frame: Prior to the start of intervention,3 months and 6 months (completion of the intervention)
Activities of Daily Living (ADLs)
Time frame: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
The Mini-Cog Score
Time frame: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)
21-item Fall Risk Index questionnaire
Time frame: Prior to the start of intervention,3 months and 6 months (completion of the intervention)
Instrumental Activities of Daily Living (IADLs)
Time frame: First visit, 3 months, 6 months

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 1 Apr 2026.
Background: PubMed 16978493Topolski TD, LoGerfo J, Patrick DL, Williams B, Walwick J, Patrick MB. The Rapid Assessment of Physical Activity (RAPA) among older adults. Prev Chronic Dis. 2006 Oct;3(4):A118. Epub 2006 Sep 15.
Background: PubMed 33381698Buyukavci R, Akturk S, Evren B, Ersoy Y. Impacts of combined osteopenia/osteoporosis and sarcopenia on balance and quality of life in older adults. North Clin Istanb. 2020 Oct 1;7(6):585-590. doi: 10.14744/nci.2020.28003. eCollection 2020.
Background: PubMed 32273572Zhang XL, Zhang Z, Zhu YX, Tao J, Zhang Y, Wang YY, Ke YY, Ren CX, Xu J, Zhang XY. Comparison of the efficacy of Nutritional Risk Screening 2002 and Mini Nutritional Assessment Short Form in recognizing sarcopenia and predicting its mortality. Eur J Clin Nutr. 2020 Jul;74(7):1029-1037. doi: 10.1038/s41430-020-0621-8. Epub 2020 Apr 9.
Background: PubMed 36418975Beltz S, Gloystein S, Litschko T, Laag S, van den Berg N. Multivariate analysis of independent determinants of ADL/IADL and quality of life in the elderly. BMC Geriatr. 2022 Nov 23;22(1):894. doi: 10.1186/s12877-022-03621-3.
Background: PubMed 31534342Nguyen TTH, Vu HTT, Nguyen TN, Dao HT, Nguyen TX, Nguyen HTT, Dang AK, Nguyen AT, Pham T, Vu GT, Tran BX, Latkin CA, Ho CS, Ho RC. Assessment of nutritional status in older diabetic outpatients and related factors in Hanoi, Vietnam. J Multidiscip Healthc. 2019 Jul 30;12:601-606. doi: 10.2147/JMDH.S194155. eCollection 2019.
Background: PubMed 35870875Sanchez-Sanchez JL, Udina C, Medina-Rincon A, Esbri-Victor M, Bartolome-Martin I, Moral-Cuesta D, Marin-Epelde I, Ramon-Espinoza F, Latorre MS, Idoate F, Goni-Sarries A, Martinez-Martinez B, Bonet RE, Librero J, Casas-Herrero A. Effect of a multicomponent exercise program and cognitive stimulation (VIVIFRAIL-COGN) on falls in frail community older persons with high risk of falls: study protocol for a randomized multicenter control trial. BMC Geriatr. 2022 Jul 23;22(1):612. doi: 10.1186/s12877-022-03214-0.
Background: PubMed 33139628Tamura Y, Omura T, Toyoshima K, Araki A. Nutrition Management in Older Adults with Diabetes: A Review on the Importance of Shifting Prevention Strategies from Metabolic Syndrome to Frailty. Nutrients. 2020 Nov 1;12(11):3367. doi: 10.3390/nu12113367.
Background: PubMed 29722845Lopez-Garcia E, Hagan KA, Fung TT, Hu FB, Rodriguez-Artalejo F. Mediterranean diet and risk of frailty syndrome among women with type 2 diabetes. Am J Clin Nutr. 2018 May 1;107(5):763-771. doi: 10.1093/ajcn/nqy026.
Background: PubMed 35057493Gobl C, Tura A. Focus on Nutritional Aspects of Sarcopenia in Diabetes: Current Evidence and Remarks for Future Research. Nutrients. 2022 Jan 13;14(2):312. doi: 10.3390/nu14020312.
Background: PubMed 34144317O'Donovan M, Sezgin D, O'Caoimh R, Liew A. The relationship between frailty and diabetes: An investigation of self-rated health, depression symptoms and quality of life in the Study of Health Aging and Retirement in Europe. Arch Gerontol Geriatr. 2021 Sep-Oct;96:104448. doi: 10.1016/j.archger.2021.104448. Epub 2021 May 29.
Background: PubMed 29412437Sinclair AJ, Abdelhafiz A, Dunning T, Izquierdo M, Rodriguez Manas L, Bourdel-Marchasson I, Morley JE, Munshi M, Woo J, Vellas B. An International Position Statement on the Management of Frailty in Diabetes Mellitus: Summary of Recommendations 2017. J Frailty Aging. 2018;7(1):10-20. doi: 10.14283/jfa.2017.39.
Background: PubMed 33313578Hanlon P, Faure I, Corcoran N, Butterly E, Lewsey J, McAllister D, Mair FS. Frailty measurement, prevalence, incidence, and clinical implications in people with diabetes: a systematic review and study-level meta-analysis. Lancet Healthy Longev. 2020 Dec;1(3):e106-e116. doi: 10.1016/S2666-7568(20)30014-3.

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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Ngan Thi Kim Duong, Master study director

Phu Tho Province General Hospital

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Vivifrail Exercise Programme Training in people with Type 2 Diabetes and Fraity Syndrome, run by National Geriatric Hospital at 1 site in Vietnam.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 1 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Vietnam. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Physical performance 1 - Handgrip strength (time frame: Prior to the start of intervention, 3 months and 6 months (completion of the intervention)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07506278, which also lists 24 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Apr 2026.