HealthyPTNCT07508150
Anthropometric Normalization in Inter-Individual Variability of Comprehensive Isokinetic Strength Assessment
An observational study of Healthy, run by Cairo University at 1 site in Egypt.
Trial summary
Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition. While body weight (BW) is commonly used, body mass index (BMI) may provide a more stable representation of inter-individual variability. Read more about this study
- Who is it for?
- Ages 25 to 35 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- effects of BW versus BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female
- How many people
- 112 participants
- Where
- 1 siteEgypt
- Study dates
- 30 Mar 2026to 30 Apr 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 35 years
- Women only
- Healthy volunteers accepted
- Adult
Study population: A total of 112 healthy sedentary females volunteered to participate in the study. Their demographic characteristics including age, weight, height and BMI are illustrated in Table 1. Ethical approval was obtained from the Research Ethics Committee of the Faculty of Physical Therapy, Cairo University. Prior to enrollment, all participants provided written informed consent after receiving a comprehensive explanation of the study objectives, procedures, and their rights as research subjects. All procedures were performed in accordance with the Helsinki Declaration. All participants provided informed written consent prior to participation, aligning with ethical standards for research with human subjects.
Who may be able to join
- he absence of any current or prior musculoskeletal injury or pain affecting the trunk, pelvis, or lower extremities within the preceding six months.
- absence of neurological, cardiovascular, or systemic conditions that could influence muscle strength or motor performance.
- a normal BMI relative to their age and sex and were recreationally active without engaging in any structured strength training program targeting the trunk or hip muscles during the three months preceding the study.
- all participants were able to comprehend the study procedures and provide written informed consent.
Who cannot join
- any history of musculoskeletal injury, surgery, or chronic pain involving the spine, pelvis, hip, knee, or ankle. Individuals with diagnosed neurological disorders, balance impairments, or vestibular conditions were also ineligible.
- cardiovascular, respiratory, or systemic diseases that could affect physical performance or muscle strength were excluded
- a prior history of lower limb or trunk fractures. Individuals engaged in competitive sports or structured resistance training programs targeting the trunk and lower limb muscles within the preceding three months were not included.
- musculoskeletal deformities, leg length discrepancies, or any other condition that could interfere with the testing procedures
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Role of Anthropometric Normalization in Inter-Individual Variability of Comprehensive Isokinetic Strength Assessment in Healthy Women: A Methodological Study
Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition. While body weight (BW) is commonly used, body mass index (BMI) may provide a more stable representation of inter-individual variability. The study aims to compare the effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female participants.
Read the detailed description
Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition. While body weight (BW) is commonly used, body mass index (BMI) may provide a more stable representation of inter-individual variability. The study aims to compare the effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female participants.
Thirty healthy adult females will undergo isokinetic testing of trunk flexors/extensors, hip flexors/extensors/abductors/adductors, and knee flexors/extensors. PT values will be normalized to BW and BMI. Coefficient of variation (CV%) will be calculated for each method to evaluate relative variability.
- Conditions
- Healthy
- Being tested
- effects of BW versus BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female
- Keywords
- Isokinetic strength, Peak torque, Normalization, Body weight, Body mass index
- Medical subject headings
- Body Weight
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
effects of BW versus BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy femaleDiagnostic test
effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female
What is being measured
The primary outcome is the main question the study is designed to answer.
trunk muscle peak torque
Isokinetic trunk muscle strength testing
Measured: two weeks
hip muscle peak torque
Isokinetic hip muscle strength testing
Measured: two weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Apr 2026
- Study start30 Mar 2026 (estimated)
- Primary completion28 Apr 2026 (estimated)
- Study completion30 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 112 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Azza Mohammed, Cairo University
- Investigators
- Azza M, professor, Principal investigator, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07508150
- Sponsor's protocol ID
- Approved by IRB
- Acronym
- PT
- Status last verified
- Apr 2026
- First submitted
- 27 Mar 2026
- Last updated
- 9 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Role of Anthropometric Normalization in Inter-Individual Variability of Comprehensive Isokinetic Strength Assessment in Healthy Women: A Methodological Study
- ClinicalTrials.gov ID
- NCT07508150
- Acronym / sponsor ID
- PT / Approved by IRB
- Conditions
- Healthy
- Keywords
- Isokinetic strength, Peak torque, Normalization, Body weight, Body mass index
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 112 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 30 Mar 2026 (estimated)
- Primary completion
- 28 Apr 2026 (estimated)
- Study completion
- 30 Apr 2026 (estimated)
- First posted
- 2 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition. While body weight (BW) is commonly used, body mass index (BMI) may provide a more stable representation of inter-individual variability. The study aims to compare the effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female participants.
Detailed description
Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition. While body weight (BW) is commonly used, body mass index (BMI) may provide a more stable representation of inter-individual variability. The study aims to compare the effects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female participants.
Thirty healthy adult females will undergo isokinetic testing of trunk flexors/extensors, hip flexors/extensors/abductors/adductors, and knee flexors/extensors. PT values will be normalized to BW and BMI. Coefficient of variation (CV%) will be calculated for each method to evaluate relative variability.
Study design
- Observational model
- Other
- Time perspective
- Prospective
Who may qualify
- Ages
- 25 to 35 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- A total of 112 healthy sedentary females volunteered to participate in the study. Their demographic characteristics including age, weight, height and BMI are illustrated in Table 1. Ethical approval was obtained from the Research Ethics Committee of the Faculty of Physical Therapy, Cairo University. Prior to enrollment, all participants provided written informed consent after receiving a comprehensive explanation of the study objectives, procedures, and their rights as research subjects. All procedures were performed in accordance with the Helsinki Declaration. All participants provided informed written consent prior to participation, aligning with ethical standards for research with human subjects.
Key inclusion criteria (4 listed)
- he absence of any current or prior musculoskeletal injury or pain affecting the trunk, pelvis, or lower extremities within the preceding six months.
Key exclusion criteria (4 listed)
- any history of musculoskeletal injury, surgery, or chronic pain involving the spine, pelvis, hip, knee, or ankle. Individuals with diagnosed neurological disorders, balance impairments, or vestibular conditions were also ineligible.
- cardiovascular, respiratory, or systemic diseases that could affect physical performance or muscle strength were excluded
- a prior history of lower limb or trunk fractures. Individuals engaged in competitive sports or structured resistance training programs targeting the trunk and lower limb muscles within the preceding three months were not included.
- musculoskeletal deformities, leg length discrepancies, or any other condition that could interfere with the testing procedures
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| effects of BW versus BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy femaleeffects of BW and BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female | Diagnostic test | – |
Primary outcome
trunk muscle peak torque
Time frame: two weeks
Isokinetic trunk muscle strength testing
hip muscle peak torque
Time frame: two weeks
Isokinetic hip muscle strength testing
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Apr 2026.
- An Optimization Method for Predicting Torque Control of Permanent Magnet Synchronous Motor Models Using Normalized Substitution of Weight FactorsLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Azza M, professor principal investigator
Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Healthy, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 9 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Azza M Abdelmohsen, professor (01145046304, dr_azzamohammed@yahoo.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
trunk muscle peak torque (time frame: two weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Apr 2026.