AsthmaNCT07508280
Effects of Energy Conservation Exercises Versus Circuit Training in Asthmatic Patients
A study testing Energy Conservation Technique and Circuit Training in people with Asthma, run by Riphah International University at 1 site in Pakistan.
Trial summary
The aim of this study was to evaluate the Effects of energy conservation exercises versus circuit training on dyspnea, functional capacity and quality of life in asthmatic patients. Read more about this study
- Who is it for?
- Ages 30 to 50 years
- Conditions the study is for
- Asthma
- What is being tested?
- Energy Conservation Technique and Circuit Training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 32 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Feb 2026to May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Subjects with asthma diagnosis grade according to FEV 60%-80%
Who cannot join
- Pregnancy
- Previous breathing exercise training
- Severe comorbidity
- Patients with short life expectancy
- subjects with Severe physical impairments
- Subjects with Mental disease
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Doctor's hospital
Jhang, Punjab Province, 35200
Qurat ul Ain, +92 3207374003, qurat.ain@riphah.edu.pk
Malaika Ashraf, CPPT
About this study
Official title: Effects of Energy Conservation Exercises Versus Circuit Training on Dyspnea, Functional Capacity and Quality of Life in Asthmatic Patients
The aim of this study was to evaluate the Effects of energy conservation exercises versus circuit training on dyspnea, functional capacity and quality of life in asthmatic patients.
Read the detailed description
Asthma is a chronic lung disease characterized by airway inflammation and constriction, presents ongoing challenges despite advancements in treatment.The aim of this study is to found out the comparative effects of energy conservation techniques versus circuit training on dyspnea, functional capacity and quality of life in asthmatic patients. Method: This study will be conducted at "Doctors Hospital" Jhang, it is randomized clinical trial (RCT) which will divided into two groups: Group A include energy conservation techniques with the baseline exercise which is diaphragmatic exercise and Group B include circuit training along with baseline exercise. Total 32 subjects will be recruited according inclusion and exclusions criteria by convenient sampling technique. Data collection procedure will follow standardized procedures like pre-assessment and post-assessment which will be after 4 weeks with 6MWT, dyspnea borg scale, and STGeorge questionnaire. Hypothesis postulated that the one intervention will be more affected than the other. However, null hypothesis will suggest that there is no significant difference between the two interventions.
- Conditions
- Asthma
- Being tested
- Energy Conservation Technique, Circuit Training
- Keywords
- Asthma, Energy Conservation, Circuit Training, Diaphragmatic breathing, Functional Capacity
- Medical subject headings
- Asthma
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Energy Conservation TechniqueOther
Energy conservation technique is used to focus on reducing physical fatigue and improving daily functioning through pacing, planning, prioritizing, and simplifying tasks.
- After breathing exercise as a baseline 2. Dictate some activities like that on first patient use more energy expenditure than less it might be his ADL's
Circuit TrainingOther
Circuit training is a series of exercises that involve little or no rest between repetitions. it is a resistance training for asthmatic patients at their pace.
After warm up patient move to next station which consumed higher H.R After that move to resting period like using or working on low H.R
| Study group | Role | What they receive |
|---|---|---|
| Energy conservation Technique | Experimental | Using energy conservation techniques to asthmatic patients in addition to standard treatment Receives: Other: Energy Conservation Technique |
| Circuit Training | Experimental | Using circuit Training to asthmatic patients in addition to standard treatment Receives: Other: Circuit Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
6MWT
Changes from baseline, is a safe, reliable, and valid tool for assessing functional exercise capacity in asthma patients, including those with severe, uncontrolled, or difficult-to-treat asthma.
Measured: through study completion, approximately 4 weeks
Secondary outcomes (2)
Modified Borg Dyspnea Scale
Changes from baseline, a 0-10 category ratio scale used to subjectively quantify the intensity of breathlessness or shortness of breath, particularly during physical activity or rehabilitation
Measured: through study completion, approximately 4 weeks
ST George questionnaire
Changes from baseline, to measure health-related quality of life, specifically in patients with chronic airflow obstruction diseases.
Measured: through study completion, approximately 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Apr 2026
- Study start1 Feb 2026
- Primary completionApr 2026 (estimated)
- Study completionMay 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (21)Papers the sponsor has linked to this study.
- Other trials for AsthmaStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 32 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Qurat ul Ain, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07508280
- Sponsor's protocol ID
- REC/RCRS&AHS/24/0352 Malaika
- Other IDs
- 9399
- Status last verified
- Mar 2026
- First submitted
- 27 Mar 2026
- Last updated
- 2 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Hammad H, Lambrecht BN. The basic immunology of asthma. Cell. 2021 Mar 18;184(6):1469-1485. doi: 10.1016/j.cell.2021.02.016. Epub 2021 Mar 11.
PubMed 33711259Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, Fahy JV, Fitzpatrick AM, Gaston BM, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Meyers DA, Moore WC, Peters M, Phillips BR, Phipatanakul W, Sorkness RL, Wenzel SE. Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma. Am J Respir Crit Care Med. 2019 Jun 1;199(11):1358-1367. doi: 10.1164/rccm.201808-1543OC.
PubMed 30682261Thomas D, McDonald VM, Pavord ID, Gibson PG. Asthma remission: what is it and how can it be achieved? Eur Respir J. 2022 Nov 3;60(5):2102583. doi: 10.1183/13993003.02583-2021. Print 2022 Nov.
PubMed 35361633Young TW. Fatal bronchial asthma with bilateral lung collapse. Am J Forensic Med Pathol. 2010 Dec;31(4):373-5. doi: 10.1097/PAF.0b013e3181c15948.
PubMed 21030852Shahid S, Rafique S, Shakoor AA, Sheraz M, Aamir R, Safder M, et al. A systematic review of prescription patterns and cost of treatment in Asthma management in Asian countries. Medical Science. 2024;28:e33ms3328.
Wingardh ASL, Goransson C, Larsson S, Slinde F, Vanfleteren LEGW. Effectiveness of Energy Conservation Techniques in Patients with COPD. Respiration. 2020;99(5):409-416. doi: 10.1159/000506816. Epub 2020 Apr 9.
PubMed 32272478Prieur G, Combret Y, Medrinal C, Arnol N, Bonnevie T, Gravier FE, Quieffin J, Lamia B, Reychler G, Borel JC. Energy conservation technique improves dyspnoea when patients with severe COPD climb stairs: a randomised crossover study. Thorax. 2020 Jun;75(6):510-512. doi: 10.1136/thoraxjnl-2019-214295. Epub 2020 Mar 26.
PubMed 32217783Kozu R, Shingai K, Hanada M, Oikawa M, Nagura H, Ito H, Kitagawa C, Tanaka T. Respiratory Impairment, Limited Activity, and Pulmonary Rehabilitation in Patients with Interstitial Lung Disease. Phys Ther Res. 2021 Apr 1;24(1):9-16. doi: 10.1298/ptr.R0012. eCollection 2021.
PubMed 33981523Cazorla S, Busegnies Y, D'Ans P, Heritier M, Poncin W. Breathing Control Exercises Delivered in a Group Setting for Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial. Healthcare (Basel). 2023 Mar 17;11(6):877. doi: 10.3390/healthcare11060877.
PubMed 36981534Mazzarin CM, Silveira BR, Lamezon AC, Cavon Luna B, Valderramas S. Effectiveness and Safety of Multicomponent Physical Training in Patients With Chronic Obstructive Pulmonary Disease: Protocol for a Randomized Clinical Trial. Health Serv Insights. 2023 May 2;16:11786329231169255. doi: 10.1177/11786329231169255. eCollection 2023.
PubMed 37153879Klimczak MK, Krzepkowski HA, Piotrowski WJ, Bialas AJ. The Short-Term Efficacy of a Three-Week Pulmonary Rehabilitation Program among Patients with Obstructive Lung Diseases. J Clin Med. 2024 Apr 27;13(9):2576. doi: 10.3390/jcm13092576.
PubMed 38731105Solanke AV, Lalwani L. Incorporating RC-Cornet PLUS and POWERbreathe Medic Plus Device Along With Pulmonary Rehabilitation on Functional Capacity and Quality of Life in Bronchiectasis: A Case Report. Cureus. 2025 Feb 21;17(2):e79433. doi: 10.7759/cureus.79433. eCollection 2025 Feb.
PubMed 40130109Bruton A, Lee A, Yardley L, Raftery J, Arden-Close E, Kirby S, Zhu S, Thiruvothiyur M, Webley F, Taylor L, Gibson D, Yao G, Stafford-Watson M, Versnel J, Moore M, George S, Little P, Djukanovic R, Price D, Pavord ID, Holgate ST, Thomas M. Physiotherapy breathing retraining for asthma: a randomised controlled trial. Lancet Respir Med. 2018 Jan;6(1):19-28. doi: 10.1016/S2213-2600(17)30474-5. Epub 2017 Dec 14.
PubMed 29248433Sosa-Pedreschi A, Donadio MVF, Iturriaga-Ramirez T, Yvert T, Perez-Salazar F, Santiago-Dorrego C, Barcelo-Guido O, Sanz-Santiago V, Giron R, Punter RMG, Rubio-Alonso M, Perez-Ruiz M. Effects of a remotely supervised resistance training program on muscle strength and body composition in adults with cystic fibrosis: Randomized controlled trial. Scand J Med Sci Sports. 2024 Jan;34(1):e14564. doi: 10.1111/sms.14564.
PubMed 38268067Develi E, Muammer R, Kucukardali Y. Effects of Neuromuscular Electrical Stimulation on Muscle Strength, Functional Capacity, and Quality of Life Among Older Patients With Asthma. Altern Ther Health Med. 2024 Jun;30(6):6-15.
PubMed 38843418
Study at a glance
From the registry record, last updated by the sponsor on 2 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Energy Conservation Exercises Versus Circuit Training on Dyspnea, Functional Capacity and Quality of Life in Asthmatic Patients
- ClinicalTrials.gov ID
- NCT07508280
- Acronym / sponsor ID
- REC/RCRS&AHS/24/0352 Malaika
- Conditions
- Asthma
- Keywords
- Asthma, Energy Conservation, Circuit Training, Diaphragmatic breathing, Functional Capacity
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 32 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Feb 2026 (actual)
- Primary completion
- Apr 2026 (estimated)
- Study completion
- May 2026 (estimated)
- First posted
- 2 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study was to evaluate the Effects of energy conservation exercises versus circuit training on dyspnea, functional capacity and quality of life in asthmatic patients.
Detailed description
Asthma is a chronic lung disease characterized by airway inflammation and constriction, presents ongoing challenges despite advancements in treatment.The aim of this study is to found out the comparative effects of energy conservation techniques versus circuit training on dyspnea, functional capacity and quality of life in asthmatic patients. Method: This study will be conducted at "Doctors Hospital" Jhang, it is randomized clinical trial (RCT) which will divided into two groups: Group A include energy conservation techniques with the baseline exercise which is diaphragmatic exercise and Group B include circuit training along with baseline exercise. Total 32 subjects will be recruited according inclusion and exclusions criteria by convenient sampling technique. Data collection procedure will follow standardized procedures like pre-assessment and post-assessment which will be after 4 weeks with 6MWT, dyspnea borg scale, and STGeorge questionnaire. Hypothesis postulated that the one intervention will be more affected than the other. However, null hypothesis will suggest that there is no significant difference between the two interventions.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Energy conservation Technique | Experimental | Other: Energy Conservation TechniqueUsing energy conservation techniques to asthmatic patients in addition to standard treatment |
| Circuit Training | Experimental | Other: Circuit TrainingUsing circuit Training to asthmatic patients in addition to standard treatment |
Who may qualify
- Ages
- 30 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Subjects with asthma diagnosis grade according to FEV 60%-80%
Key exclusion criteria (6 listed)
- Pregnancy
- Previous breathing exercise training
- Severe comorbidity
- Patients with short life expectancy
- subjects with Severe physical impairments
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Energy Conservation TechniqueEnergy conservation technique is used to focus on reducing physical fatigue and improving daily functioning through pacing, planning, prioritizing, and simplifying tasks. 1. After breathing exercise as a baseline 2. Dictate some activities like that on first patient use more energy expenditure than less it might be his ADL's | Other | Energy conservation Technique |
| Circuit TrainingCircuit training is a series of exercises that involve little or no rest between repetitions. it is a resistance training for asthmatic patients at their pace. After warm up patient move to next station which consumed higher H.R After that move to resting period like using or working on low H.R | Other | Circuit Training |
Primary outcome
6MWT
Time frame: through study completion, approximately 4 weeks
Changes from baseline, is a safe, reliable, and valid tool for assessing functional exercise capacity in asthma patients, including those with severe, uncontrolled, or difficult-to-treat asthma.
2 secondary outcomes
Modified Borg Dyspnea Scale
Time frame: through study completion, approximately 4 weeks
ST George questionnaire
Time frame: through study completion, approximately 4 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Apr 2026.
- Background: PubMed 33711259Hammad H, Lambrecht BN. The basic immunology of asthma. Cell. 2021 Mar 18;184(6):1469-1485. doi: 10.1016/j.cell.2021.02.016. Epub 2021 Mar 11.
- Background: PubMed 30682261Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, Fahy JV, Fitzpatrick AM, Gaston BM, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Meyers DA, Moore WC, Peters M, Phillips BR, Phipatanakul W, Sorkness RL, Wenzel SE. Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma. Am J Respir Crit Care Med. 2019 Jun 1;199(11):1358-1367. doi: 10.1164/rccm.201808-1543OC.
- Background: PubMed 35361633Thomas D, McDonald VM, Pavord ID, Gibson PG. Asthma remission: what is it and how can it be achieved? Eur Respir J. 2022 Nov 3;60(5):2102583. doi: 10.1183/13993003.02583-2021. Print 2022 Nov.
- Background: PubMed 21030852Young TW. Fatal bronchial asthma with bilateral lung collapse. Am J Forensic Med Pathol. 2010 Dec;31(4):373-5. doi: 10.1097/PAF.0b013e3181c15948.
- BackgroundShahid S, Rafique S, Shakoor AA, Sheraz M, Aamir R, Safder M, et al. A systematic review of prescription patterns and cost of treatment in Asthma management in Asian countries. Medical Science. 2024;28:e33ms3328.
- Background: PubMed 32272478Wingardh ASL, Goransson C, Larsson S, Slinde F, Vanfleteren LEGW. Effectiveness of Energy Conservation Techniques in Patients with COPD. Respiration. 2020;99(5):409-416. doi: 10.1159/000506816. Epub 2020 Apr 9.
- Background: PubMed 32217783Prieur G, Combret Y, Medrinal C, Arnol N, Bonnevie T, Gravier FE, Quieffin J, Lamia B, Reychler G, Borel JC. Energy conservation technique improves dyspnoea when patients with severe COPD climb stairs: a randomised crossover study. Thorax. 2020 Jun;75(6):510-512. doi: 10.1136/thoraxjnl-2019-214295. Epub 2020 Mar 26.
- Background: PubMed 33981523Kozu R, Shingai K, Hanada M, Oikawa M, Nagura H, Ito H, Kitagawa C, Tanaka T. Respiratory Impairment, Limited Activity, and Pulmonary Rehabilitation in Patients with Interstitial Lung Disease. Phys Ther Res. 2021 Apr 1;24(1):9-16. doi: 10.1298/ptr.R0012. eCollection 2021.
- Background: PubMed 36981534Cazorla S, Busegnies Y, D'Ans P, Heritier M, Poncin W. Breathing Control Exercises Delivered in a Group Setting for Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial. Healthcare (Basel). 2023 Mar 17;11(6):877. doi: 10.3390/healthcare11060877.
- Background: PubMed 37153879Mazzarin CM, Silveira BR, Lamezon AC, Cavon Luna B, Valderramas S. Effectiveness and Safety of Multicomponent Physical Training in Patients With Chronic Obstructive Pulmonary Disease: Protocol for a Randomized Clinical Trial. Health Serv Insights. 2023 May 2;16:11786329231169255. doi: 10.1177/11786329231169255. eCollection 2023.
- Background: PubMed 38731105Klimczak MK, Krzepkowski HA, Piotrowski WJ, Bialas AJ. The Short-Term Efficacy of a Three-Week Pulmonary Rehabilitation Program among Patients with Obstructive Lung Diseases. J Clin Med. 2024 Apr 27;13(9):2576. doi: 10.3390/jcm13092576.
- Background: PubMed 40130109Solanke AV, Lalwani L. Incorporating RC-Cornet PLUS and POWERbreathe Medic Plus Device Along With Pulmonary Rehabilitation on Functional Capacity and Quality of Life in Bronchiectasis: A Case Report. Cureus. 2025 Feb 21;17(2):e79433. doi: 10.7759/cureus.79433. eCollection 2025 Feb.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Qurat ul Ain principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Energy Conservation Technique and Circuit Training in people with Asthma, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Dr Imran Amjad, PhD ((+92) 03324390125, imran.amjad@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
6MWT (time frame: through study completion, approximately 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07508280, which also lists 21 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Apr 2026; AzTrials last refreshed its copy on 7 Nov 2026.