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Skin HealthNCT07510581

Evaluatation of a Microcurrent + Cold Therapy Device

A study testing Acute Microcurrent Treatment, Acute Microcurrent + cold therapy and 8-week Chronic Use of Microcurrent + Cold Therapy in people with Skin Health, run by Therabody, Inc. at 1 site in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The present study aims to assess use of a microcurrent and cryotherapy device on skin health over an 8-week period using an at-home device that provides 15-minutes of microcurrent + cold therapy once daily. Read more about this study

Who is it for?
Ages 25 to 65 years
Conditions the study is for
Skin Health
What is being tested?
Acute Microcurrent Treatment, Acute Microcurrent + cold therapy and 8-week Chronic Use of Microcurrent + Cold Therapy
Type of treatment
Medical device
Could I receive a placebo?
No, everyone receives an active treatment
How many people
112 participants
Where
1 siteUnited States
Study dates
30 Mar 2026to 1 Sep 2026
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 25 to 65 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Subject is female or male (approximately 85% female and 15% male)
  • Subject is between the ages of 25-65 (no more than 25% 55-65 per group)
  • Individuals with fine lines/wrinkles, lack of firmness, dullness, and uneven skin tone with a grade of at least 3 on a 10-point scale.
  • Individuals with sensitive skin.
  • Individuals who are able to cooperate with the Principal Investigator and study personnel throughout the duration of the study and are willing to comply with all study procedures, methods, evaluations, and study product use.
  • Individuals who are able to read and sign and informed consent.
  • Individuals who are able to receive emails on their cellular phones and are capable of completing electronic Informed Consents and/or Questionnaires on their device.
  • Individuals willing to be photographed and sign a model release.

Who cannot join

  • Individuals who have had Botox in the last 3 months prior to Baseline.
  • Individuals who have had Filler (Including Lip Filler) in the last 6 months prior to Baseline.
  • Individuals with a history of atopic eczema, psoriasis, or onychomycosis.
  • Individuals who have used a topical or system medication within 14 days prior to Baseline.
  • Individuals who are on anti-acne drugs, topical and/or oral retinoids.
  • Individuals currently on GLP1 medications or other weight loss regimens.
Show all 23Show fewer
  • Individuals who have used a beauty device of any kind in a clinical testing facility in the past 5 months prior to Baseline.
  • Individuals who have used self-tanners and/or tanning beds within 14 days prior to Baseline.
  • Individuals currently participating in other clinical studies that are testing a face product and/or device.
  • Individuals with uncontrolled medical condition(s), including dermatological problems, which could put them at risk in the opinion of the Principal Investigator or compromise the study outcome and/or chronic or serious diseases and conditions which would prevent participation in this clinical study such as cancer, AIDS, insulin-dependent diabetes, renal impairment, mental illness, and/or drug/alcohol addiction.
  • Individuals with a history of melanoma, or a treated skin cancer within the last 5 years.
  • Individuals who are pregnant, lactating, or planning to become pregnant. -Individuals who become pregnant during the study must inform the Principal Investigator immediately.
  • Individuals who are unreliable or unlikely to be available for the duration of the study.
  • Individuals with a history of allergic reactions, skin sensitization and/or known allergies to cosmetic and personal care products/ingredients.
  • Individuals who are immunocompromised.
  • Individuals who are employees of VCS, other testing firms/laboratories, consumer products, and/or raw goods manufacturers/suppliers.
  • Individuals who are unable to communicate or cooperate with the Principal Investigator/study personnel due to language problems, poor mental development, or impaired cerebral function.
  • Individuals who started hormones within the last three months preceding the commencement of the study.
  • Individuals who are using oral contraception for less than three months before study commencement or who have changed their contraceptive method within the three months before the Baseline visit or planning to modify their contraception treatment within the duration of the study.
  • Individuals who have regular salon and/or dermatological procedures that can interfere with study results (Microdermabrasion, Fillers, Facial Peels, etc.) and are not willing to stop throughout the study.
  • Individuals with facial tattoos and facial piercings (that can't be removed).
  • Individuals with tattooed/permanent make up (i.e., eyeliner, eyebrows, lip liner, etc.), eyebrow microblading, and/or eyelash extensions.
  • Individuals who plan to change their hairstyle throughout the course of the study or who wear hair coverings regularly (i.e., wigs, coloring, extensions, etc.).

Trial locations and contacts

1 site in 1 country.

United States1 site
  • Validated Claim Support

    Teaneck, New Jersey, 07666

Other trials in United States

About this study

Official title: An 8 Week Randomized, Crossover Study to Evaluate the Efficacy of a Microcurrent + Cold Therapy Device

The present study aims to assess use of a microcurrent and cryotherapy device on skin health over an 8-week period using an at-home device that provides 15-minutes of microcurrent + cold therapy once daily. An additional aim is to assess the acute (i.e., single) use of microcurrent or microcurrent + cold therapy on measures of skin health. The primary question it seeks to answer is whether daily use of the TheraFace Pro Gen 2 alters facial skin characteristics. Secondary aims include collecting clinical images, professional photographs, and consumer perceptions of the device.

Participants between the ages of 25-65 with various skin types will be enrolled for participation. Participants will visit the clinic three times for collection of outcome metrics at baseline with microcurrent therapy, baseline 2 using microcurrent + cold therapy, and 8 weeks after baseline. Measurements include: expert clinical grading, digital imaging, subjective assessment of skin, and clinical grade-images.

Read the detailed description

At home treatments to minimize and/or reverse the effects of skin aging has been gaining popularity over time. Two treatments commonly used in spa-settings to achieve these goals are microcurrent therapy and cold-therapy. Microcurrent therapy is a gentle skin treatment that uses low-level voltage to stimulate the facial muscles. This low-level voltage is applied during microcurrent facials to help tone and firm the skin by causing subtle muscle contractions. Localized cold therapy helps reduce inflammation by narrowing blood vessels and decreasing blood flow to the treated area. The central aim of this study is to investigate both acute and chronic (8 weeks) use of an at-home device that delivers both microcurrent and cold therapy on skin health. Participants will complete two acute baseline visits in randomized order, microcurrent alone and microcurrent + cold therapy in order to assess the acute effects of this therapy. Participants will then complete 8-weeks of microcurrent + cold therapy lasting about 8 minutes/day using the Therabody TheraFace Pro Gen 2 at home. Outcome measures include expert assessment and participant subjective health of skin of the face.

Conditions
Skin Health
Being tested
Acute Microcurrent Treatment, Acute Microcurrent + cold therapy, 8-week Chronic Use of Microcurrent + Cold Therapy

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Acute Microcurrent TreatmentDevice

    The esthetician will apply only the microcurrent setting during the 18-step routine.

  • Acute Microcurrent + cold therapyDevice

    The esthetician will apply cold + microcurrent therapy during the 18-step routine.

  • 8-week Chronic Use of Microcurrent + Cold TherapyDevice

    Participants will be instructed to use the TheraFace Pro Gen 2 for approximately 8 minutes a day following an 18-step routine on each side of the face. The steps include: ower neck (glide), upper neck (glide), vertical neck (glide), neck contour (glide), neck contour (press + hold), jawline cradle (glide), jawline cradle (press + hold), jaw contour (glide), jaw contour (press + hold), cheek contour (glide), cheek contour (press + hold), cheekbone contour (glide), cheek contour (press + hold), brow lift (glide), brow lift (press + hold), eye contour (glide), eye contour (press + hold), inner brow (glide), \& inner brow (press + hold). Each location will receive ~10 seconds of treatment.

Study groups in NCT07510581
Study groupRoleWhat they receive
Acute Application of Microcurrent by EstheticianExperimentalA licensed esthetician will complete an 18-step routine on the right and left side of the face including: lower neck (glide), upper neck (glide), vertical neck (glide), neck contour (glide), neck contour (press + hold), jawline cradle (glide), jawline cradle (press + hold), jaw contour (glide), jaw contour (press + hold), cheek contour (glide), cheek contour (press + hold), cheekbone contour (glide), cheek contour (press + hold), brow lift (glide), brow lift (press + hold), eye contour (glide), eye contour (press + hold), inner brow (glide), \& inner brow (press + hold).
Receives: Device: Acute Microcurrent Treatment; Device: Acute Microcurrent + cold therapy
Chronic Use of Microcurrent + Cold TherapyExperimentalAll evaluations will occur after sitting in 15-minutes of ambient conditions. Participants will be instructed to use the TheraFace Pro Gen 2 for approximately 8 minutes a day following an 18-step routine on each side of the face. The steps include: ower neck (glide), upper neck (glide), vertical neck (glide), neck contour (glide), neck contour (press + hold), jawline cradle (glide), jawline cradle (press + hold), jaw contour (glide), jaw contour (press + hold), cheek contour (glide), cheek contour (press + hold), cheekbone contour (glide), cheek contour (press + hold), brow lift (glide), brow lift (press + hold), eye contour (glide), eye contour (press + hold), inner brow (glide), \& inner brow (press + hold). Each location will receive ~10 seconds of treatment.
Receives: Device: 8-week Chronic Use of Microcurrent + Cold Therapy

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Expert grading

    Expert clinical grading will be used to measure a variety of skin health appearance measures including: fine lines/wrinkles, firmness, elasticity, radiance plumping (lips), contour (cheeks), pore appearance, lift (mid-face and jowls), nasolabial folds, and skin tone evenness. These will be graded on a scale from 0 to 10, with 0 representing a positive outcome (i.e., no wrinkles) and 10 representing a negative outcome (i.e., numerous, deep wrinkles). These will be assessed by an expert grader.

    Measured: 8-weeks

  2. Cutometer

    The Cutometer MPA 580 measures the viscoelastic properties of the skin using suction and a probe to determine the penetration depth using an optical measuring system. The resistance of the skin to be sucked up by the negative pressure (firmness) and its ability to return to its original position (elasticity) are calculated and displayed as curves. The Cutometer outputs include many parameters of different portions of the measurement curve including R0 (Uf, firmness), R2 (Ua/Uf, gross elasticity), R5 (Ur/Ue, net elasticity), R7 (Ur/Uf, elastic portion) and R9 (R3[last max amp]-R0[Uf], fatigue). Elasticity will be reported using the R5 (Ur/Ue) parameter, as the skin becomes more elastic this value will increase. Skin Firmness will be reported using the R0 (Uf) parameter, as the skin becomes firmer this value will decrease. R0 (elasticity) and R5 (firmness) will be the only two parameters provided.

    Measured: 8 weeks

  3. VISIA CR Imaging

    The VISIA-CR is a clinical facial imaging system used to analyze skin conditions. Images are taken in a variety of lighting conditions (Standard 1, Raked, Cross Polarized, and Primos 3D) to assess wrinkle depth and texture. Images will be taken of the face, utilizing the following angles: 45 degrees right, straight on, and 45 degrees left with the following lighting conditions: Standard 1, Raked, Cross Polarized, and Primos 3D. Analysis is performed by Canfield. The VISIA-CR provides a percentile value compared to others with similar skin (the higher the better); the feature count (the lower the better) and the absolute score (the lower the better).

    Measured: 8 weeks

  4. Clinical Photography

    Clinical photography involves analysis of high-resolution images taken at different angles (45 degrees right, straight on, 45 degrees left) to compare in a side-by-side format at each time point. Images at each time point will be compared to highlight key changes in skin condition.

    Measured: 8 weeks

  5. Participant perceptions of skin health

    Participants will complete subjective questionnaires ranking the impact of the treatment on overall skin health measures, including: finelines, facial puffiness, bounce, resiliency, sculpting of jawline, firmness, lift, plumping (lips), texture, comfort, plumpness, facial contour, rejuvenation, skin tone, sagging skin, and liveliness. Participants will also rank enjoyment, convenience, ease of use, and comfort of device usage. All measures will be ranked on a 5-point Likert scale, with 0 indicating strongly disagree and 5 indicating strongly agree.

    Measured: 8 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted3 Apr 2026
  2. Study start30 Mar 2026
  3. Primary completion10 Jun 2026
  4. Study completion1 Sep 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Crossover
Model description
Participants will recieve the acute microcurrent and microcurrent + cold treatment by a licensed esthitican in a randomized order. There will be one visit for each treatment with a 24hr washout. Then all participants will complete the 8-week chronic intervention.
Masking
Single blind
Who is masked
Participant
Enrolment
112 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07510581
Sponsor's protocol ID
PR251054.V03
Status last verified
Sep 2026
First submitted
26 Mar 2026
Last updated
1 Oct 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing Acute Microcurrent Treatment, Acute Microcurrent + cold therapy and 8-week Chronic Use of Microcurrent + Cold Therapy in people with Skin Health, run by Therabody, Inc. at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 8 inclusion and 23 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 1 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Expert grading (time frame: 8-weeks). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Oct 2026.

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