Cognitive Function AssessmentNCT07511270
Prediction of Cognitive Test Performance Using AI-Based Analysis of Narrative Speech
A study testing AI-Based Storytelling Speech Assessment in people with Cognitive Function Assessment and Mild Cognitive Impairment, run by Chang Gung Memorial Hospital at 1 site in Taiwan.
Trial summary
This study aims to evaluate a new artificial intelligence (AI)-based method for measuring cognitive function using speech recordings. Participants will complete a short storytelling task in which they describe a story based on an image while their voice is recorded using a computer or mobile device. Read more about this study
- Who is it for?
- Ages 50 years and olderHealthy volunteers can take part
- Conditions the study is for
- Cognitive Function Assessment, Mild Cognitive Impairment, Subjective Cognitive Decline
- What is being tested?
- AI-Based Storytelling Speech Assessment
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 150 participants
- Where
- 1 siteTaiwan
- Study dates
- 1 Dec 2025to 30 Apr 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Age 50 years or older
- Able to communicate verbally and understand study instructions
- Able to hear and speak clearly
- Willing and able to provide written informed consent
Who cannot join
- Severe speech or hearing impairment
- History of major psychiatric disorders
- History of stroke, traumatic brain injury, Parkinson's disease, epilepsy, or other neurodegenerative diseases
- Current use of medications that may affect cognitive performance
- Unable to complete the study procedures due to severe attention deficits or agitation
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site, 1 recruiting
- Recruiting
Taoyuan
Taoyuan
Ching-Yi WU, ScD, +886-3-2118800 ext. 5761, cywu@mail.cgu.edu.tw
About this study
This study aims to evaluate a new artificial intelligence (AI)-based method for measuring cognitive function using speech recordings. Participants will complete a short storytelling task in which they describe a story based on an image while their voice is recorded using a computer or mobile device.
The speech recordings will be analyzed using AI technology to identify patterns in speech that may be related to cognitive function. The system will then estimate scores that correspond to commonly used cognitive tests.
Read more
To evaluate the accuracy of this method, the AI-generated scores will be compared with results from standard cognitive assessments administered by trained researchers. These assessments may include tests commonly used to measure memory, attention, and other cognitive abilities.
The goal of this study is to determine whether speech analysis using AI can provide a convenient and efficient approach for cognitive assessment. If successful, this technology may help support early detection of cognitive decline and provide a practical tool for large-scale or remote cognitive screening.
- Being tested
- AI-Based Storytelling Speech Assessment
- Keywords
- Artificial Intelligence, Speech Biomarkers, Storytelling Task, Cognitive Screening, Voice Analysis, Mild Cognitive Impairment
- Medical subject headings
- Cognitive Dysfunction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
AI-Based Storytelling Speech AssessmentBehavioural
Participants will be asked to describe a short story based on a randomly presented image while their speech is recorded using a web-based system on a computer or mobile device. The recorded speech will be analyzed using artificial intelligence algorithms to extract acoustic and linguistic features that may reflect cognitive function.
| Study group | Role | What they receive |
|---|---|---|
| storytelling speech task | Experimental | Participants will complete a storytelling speech task using a web-based platform followed by standardized cognitive assessments administered by trained research personnel. Receives: Behavioral: AI-Based Storytelling Speech Assessment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Correlation Between AI-Predicted Cognitive Scores and Standard Cognitive Assessment Scores
The correlation between cognitive scores predicted by the AI-based speech analysis system and scores obtained from clinician-administered cognitive assessments, including the Mini-Mental State Examination (MMSE) and the Wechsler Adult Intelligence Scale (WAIS).
Measured: Immediately after completion of the study session
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Apr 2026
- Study start1 Dec 2025
- Primary completion31 Mar 2026 (estimated)
- Study completion30 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cognitive Function AssessmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 150 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Chang Gung Memorial Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07511270
- Sponsor's protocol ID
- 202501155B0
- Status last verified
- Mar 2026
- First submitted
- 30 Mar 2026
- Last updated
- 6 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 6 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prediction of Cognitive Test Performance Using AI-Based Analysis of Narrative Speech
- ClinicalTrials.gov ID
- NCT07511270
- Acronym / sponsor ID
- 202501155B0
- Keywords
- Artificial Intelligence, Speech Biomarkers, Storytelling Task, Cognitive Screening, Voice Analysis, Mild Cognitive Impairment
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 150 participants (estimated)
- Lead sponsor
- Chang Gung Memorial HospitalUniversity, hospital or other
- Study start
- 1 Dec 2025 (actual)
- Primary completion
- 31 Mar 2026 (estimated)
- Study completion
- 30 Apr 2026 (estimated)
- First posted
- 6 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate a new artificial intelligence (AI)-based method for measuring cognitive function using speech recordings. Participants will complete a short storytelling task in which they describe a story based on an image while their voice is recorded using a computer or mobile device.
The speech recordings will be analyzed using AI technology to identify patterns in speech that may be related to cognitive function. The system will then estimate scores that correspond to commonly used cognitive tests.
To evaluate the accuracy of this method, the AI-generated scores will be compared with results from standard cognitive assessments administered by trained researchers. These assessments may include tests commonly used to measure memory, attention, and other cognitive abilities.
The goal of this study is to determine whether speech analysis using AI can provide a convenient and efficient approach for cognitive assessment. If successful, this technology may help support early detection of cognitive decline and provide a practical tool for large-scale or remote cognitive screening.
Study design
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| storytelling speech task | Experimental | Behavioral: AI-Based Storytelling Speech AssessmentParticipants will complete a storytelling speech task using a web-based platform followed by standardized cognitive assessments administered by trained research personnel. |
Who may qualify
- Ages
- 50 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age 50 years or older
- Able to communicate verbally and understand study instructions
- Able to hear and speak clearly
- Willing and able to provide written informed consent
Key exclusion criteria (5 listed)
- Severe speech or hearing impairment
- History of major psychiatric disorders
- History of stroke, traumatic brain injury, Parkinson's disease, epilepsy, or other neurodegenerative diseases
- Current use of medications that may affect cognitive performance
- Unable to complete the study procedures due to severe attention deficits or agitation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| AI-Based Storytelling Speech AssessmentParticipants will be asked to describe a short story based on a randomly presented image while their speech is recorded using a web-based system on a computer or mobile device. The recorded speech will be analyzed using artificial intelligence algorithms to extract acoustic and linguistic features that may reflect cognitive function. | Behavioural | storytelling speech task |
Primary outcome
Correlation Between AI-Predicted Cognitive Scores and Standard Cognitive Assessment Scores
Time frame: Immediately after completion of the study session
The correlation between cognitive scores predicted by the AI-based speech analysis system and scores obtained from clinician-administered cognitive assessments, including the Mini-Mental State Examination (MMSE) and the Wechsler Adult Intelligence Scale (WAIS).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Apr 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing AI-Based Storytelling Speech Assessment in people with Cognitive Function Assessment and Mild Cognitive Impairment, run by Chang Gung Memorial Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 6 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ching-Yi WU, ScD (+886-3-2118800 ext. 5761, cywu@mail.cgu.edu.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Correlation Between AI-Predicted Cognitive Scores and Standard Cognitive Assessment Scores (time frame: Immediately after completion of the study session). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Apr 2026; AzTrials last refreshed its copy on 28 Oct 2026.