University StudentsNCT07511452
Health-Related Lifestyle Factors, Sex, and Neural Mechanosensitivity in University Students
An observational study of University Students and Health-related Lifestyle Factors, run by Fenerbahce University at 1 site in Turkey (Türkiye).
Trial summary
This observational cross-sectional study aims to investigate the effects of health-related lifestyle factors and sex on neural mechanosensitivity in university students. Specifically, the study will examine whether alcohol consumption, smoking status, physical activity level, age, body mass index, and sex are… Read more about this study
- Who is it for?
- Ages 18 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- University Students, Health-related Lifestyle Factors, Neural Mechanosensitivity
- How many people
- 55 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 30 Mar 2026to Jun 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Healthy university students aged 18 to 30 years enrolled at Fenerbahçe University will be recruited for this observational cross-sectional study. Participants must volunteer to participate, provide written informed consent, and have no condition preventing pressure pain threshold assessment in the tibial and peroneal nerve regions. Students with neurological disease, lower extremity musculoskeletal injury or surgery, acute pain, systemic conditions affecting nerve sensitivity, skin problems at the measurement site, or use of medications that may influence measurements will be excluded.
Who may be able to join
- Students enrolled at Fenerbahçe University
- Aged 18 to 30 years
- Willing to participate voluntarily
- Able to provide written informed consent
- No health problem preventing measurement in the tibial and peroneal nerve regions
Who cannot join
- Diagnosed neurological disease
- Lower extremity musculoskeletal injury, previous surgery, or acute pain
- Diabetes, peripheral neuropathy, or other systemic disease that may affect nerve sensitivity
- Open wound, infection, or skin problem at the measurement site
- Use of analgesic or neurologically active medication that may affect the measurements
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Fenerbahçe University
Istanbul, Ataşehir, 34758
About this study
Official title: The Effects of Health-Related Lifestyle Factors and Sex on Neural Mechanosensitivity in University Students
This observational cross-sectional study aims to investigate the effects of health-related lifestyle factors and sex on neural mechanosensitivity in university students. Specifically, the study will examine whether alcohol consumption, smoking status, physical activity level, age, body mass index, and sex are associated with pressure pain thresholds of the tibial and peroneal nerves.
Participants will be university students aged 18 to 30 years enrolled at Fenerbahçe University who voluntarily agree to participate and provide informed consent. Students with neurological disorders, lower extremity musculoskeletal injury or surgery, acute pain, systemic conditions affecting nerve sensitivity, skin problems at the measurement sites, or use of medications that may influence the measurements will be excluded.
Read more
Data will be collected face to face. Participants will complete a personal information form including demographic characteristics and lifestyle-related factors. Neural mechanosensitivity will be assessed by measuring pressure pain threshold over the tibial and peroneal nerve regions using a digital algometer. Three measurements will be obtained at each site and the average value will be used for analysis.
The study is expected to improve understanding of factors associated with peripheral nerve mechanosensitivity in young adults and may provide a scientific basis for future clinical and epidemiological research.
Read the detailed description
This is an observational, analytical, cross-sectional study designed to evaluate neural mechanosensitivity in healthy university students and to explore its association with health-related lifestyle factors and sex. The main objective is to determine whether alcohol consumption, smoking status, physical activity level, sex, age, and body mass index are associated with pressure pain threshold values measured over the tibial and peroneal nerves.
The study population will consist of students enrolled at Fenerbahçe University. Participants must be between 18 and 30 years of age, willing to participate voluntarily, and able to provide written informed consent. Individuals will be excluded if they have a diagnosed neurological disease, lower extremity musculoskeletal injury or previous surgery, acute pain, diabetes, peripheral neuropathy, systemic disorders that may affect nerve sensitivity, skin lesions or infection at the test site, or use of analgesic or neurologically active medication that could influence the measurements.
Data will be collected in person. After informed consent is obtained, participants will complete a personal information form developed by the investigators. This form will record sociodemographic characteristics and lifestyle-related variables, including age, sex, height, weight, alcohol consumption, smoking status, and physical activity habits. Body mass index will be calculated from height and weight data.
Neural mechanosensitivity will be assessed by pressure pain threshold measurements using a digital algometer. Measurements will be performed over standardized anatomical points corresponding to the tibial nerve and the common peroneal nerve. Pressure will be increased gradually at an approximate rate of 0.5 to 1 kg/cm²/s, and participants will be instructed to indicate when the sensation first becomes painful. Three repeated measurements will be obtained at each site, and the mean value will be used in the analyses. The algometer will be checked according to the manufacturer's calibration standards.
The planned minimum sample size is 55 participants, based on an a priori power analysis performed with G*Power 3.1, assuming an alpha of 0.05, a statistical power of 0.80, and a medium effect size. Statistical analyses will be conducted using IBM SPSS Statistics version 22. Descriptive statistics will summarize participant characteristics. Normality will be assessed using the Shapiro-Wilk test and visual methods. Group comparisons for lifestyle-related factors will be performed using one-way ANOVA, sex differences will be examined using the independent samples t-test, associations with age and body mass index will be tested using Pearson correlation analysis, and linear regression analysis will be used to further evaluate the effect of sex on pressure pain threshold values. Statistical significance will be set at p < 0.05.
This study is expected to provide information about factors associated with peripheral nerve mechanosensitivity in young adults and may contribute to future clinical and epidemiological research in physiotherapy and rehabilitation.
- Keywords
- Neural mechanosensitivity, pressure pain threshold, tibial nerve, peroneal nerve, university students
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Healthy University Students | University students aged 18 to 30 years enrolled at Fenerbahçe University who voluntarily participate in the study and undergo assessment of lifestyle factors and neural mechanosensitivity. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pressure Pain Threshold of the Tibial Nerve
Pressure pain threshold measured over the tibial nerve region using a digital algometer. Three measurements will be obtained and the mean value will be used for analysis.
Measured: At baseline (single assessment)
Pressure Pain Threshold of the Common Peroneal Nerve
Pressure pain threshold measured over the common peroneal nerve region using a digital algometer. Three measurements will be obtained and the mean value will be used for analysis.
Measured: At baseline (single assessment)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Apr 2026
- Study start30 Mar 2026
- Primary completionJun 2026 (estimated)
- Study completionJun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for University StudentsStudies of the same condition, open and under way.
- More trials run by Fenerbahce UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 55 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Fenerbahce University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sümeyye Akçay, Fenerbahce University
- Investigators
- Sümeyye Akçay, Principal investigator, Fenerbahçe UniversityDuygu Aktar Reyhanioğlu, Asst. Prof., Study chair, Fenerbahçe University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07511452
- Sponsor's protocol ID
- FenerbahceUniv
- Status last verified
- Mar 2026
- First submitted
- 30 Mar 2026
- Last updated
- 6 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: No individual participant data will be shared. The study involves a relatively small single-center sample of university students, and data sharing could increase the risk of participant re-identification. Results will be reported in aggregate form only, in accordance with ethical approval, informed consent, and applicable data protection regulations.
Study at a glance
From the registry record, last updated by the sponsor on 6 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Health-Related Lifestyle Factors and Sex on Neural Mechanosensitivity in University Students
- ClinicalTrials.gov ID
- NCT07511452
- Acronym / sponsor ID
- FenerbahceUniv
- Keywords
- Neural mechanosensitivity, pressure pain threshold, tibial nerve, peroneal nerve, university students
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 55 participants (estimated)
- Lead sponsor
- Fenerbahce UniversityUniversity, hospital or other
- Study start
- 30 Mar 2026 (actual)
- Primary completion
- Jun 2026 (estimated)
- Study completion
- Jun 2026 (estimated)
- First posted
- 6 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational cross-sectional study aims to investigate the effects of health-related lifestyle factors and sex on neural mechanosensitivity in university students. Specifically, the study will examine whether alcohol consumption, smoking status, physical activity level, age, body mass index, and sex are associated with pressure pain thresholds of the tibial and peroneal nerves.
Participants will be university students aged 18 to 30 years enrolled at Fenerbahçe University who voluntarily agree to participate and provide informed consent. Students with neurological disorders, lower extremity musculoskeletal injury or surgery, acute pain, systemic conditions affecting nerve sensitivity, skin problems at the measurement sites, or use of medications that may influence the measurements will be excluded.
Data will be collected face to face. Participants will complete a personal information form including demographic characteristics and lifestyle-related factors. Neural mechanosensitivity will be assessed by measuring pressure pain threshold over the tibial and peroneal nerve regions using a digital algometer. Three measurements will be obtained at each site and the average value will be used for analysis.
The study is expected to improve understanding of factors associated with peripheral nerve mechanosensitivity in young adults and may provide a scientific basis for future clinical and epidemiological research.
Detailed description
This is an observational, analytical, cross-sectional study designed to evaluate neural mechanosensitivity in healthy university students and to explore its association with health-related lifestyle factors and sex. The main objective is to determine whether alcohol consumption, smoking status, physical activity level, sex, age, and body mass index are associated with pressure pain threshold values measured over the tibial and peroneal nerves.
The study population will consist of students enrolled at Fenerbahçe University. Participants must be between 18 and 30 years of age, willing to participate voluntarily, and able to provide written informed consent. Individuals will be excluded if they have a diagnosed neurological disease, lower extremity musculoskeletal injury or previous surgery, acute pain, diabetes, peripheral neuropathy, systemic disorders that may affect nerve sensitivity, skin lesions or infection at the test site, or use of analgesic or neurologically active medication that could influence the measurements.
Data will be collected in person. After informed consent is obtained, participants will complete a personal information form developed by the investigators. This form will record sociodemographic characteristics and lifestyle-related variables, including age, sex, height, weight, alcohol consumption, smoking status, and physical activity habits. Body mass index will be calculated from height and weight data.
Neural mechanosensitivity will be assessed by pressure pain threshold measurements using a digital algometer. Measurements will be performed over standardized anatomical points corresponding to the tibial nerve and the common peroneal nerve. Pressure will be increased gradually at an approximate rate of 0.5 to 1 kg/cm²/s, and participants will be instructed to indicate when the sensation first becomes painful. Three repeated measurements will be obtained at each site, and the mean value will be used in the analyses. The algometer will be checked according to the manufacturer's calibration standards.
The planned minimum sample size is 55 participants, based on an a priori power analysis performed with G*Power 3.1, assuming an alpha of 0.05, a statistical power of 0.80, and a medium effect size. Statistical analyses will be conducted using IBM SPSS Statistics version 22. Descriptive statistics will summarize participant characteristics. Normality will be assessed using the Shapiro-Wilk test and visual methods. Group comparisons for lifestyle-related factors will be performed using one-way ANOVA, sex differences will be examined using the independent samples t-test, associations with age and body mass index will be tested using Pearson correlation analysis, and linear regression analysis will be used to further evaluate the effect of sex on pressure pain threshold values. Statistical significance will be set at p < 0.05.
This study is expected to provide information about factors associated with peripheral nerve mechanosensitivity in young adults and may contribute to future clinical and epidemiological research in physiotherapy and rehabilitation.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Healthy University Students | – | –University students aged 18 to 30 years enrolled at Fenerbahçe University who voluntarily participate in the study and undergo assessment of lifestyle factors and neural mechanosensitivity. |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Healthy university students aged 18 to 30 years enrolled at Fenerbahçe University will be recruited for this observational cross-sectional study. Participants must volunteer to participate, provide written informed consent, and have no condition preventing pressure pain threshold assessment in the tibial and peroneal nerve regions. Students with neurological disease, lower extremity musculoskeletal injury or surgery, acute pain, systemic conditions affecting nerve sensitivity, skin problems at the measurement site, or use of medications that may influence measurements will be excluded.
Key inclusion criteria (5 listed)
- Students enrolled at Fenerbahçe University
- Aged 18 to 30 years
- Willing to participate voluntarily
- Able to provide written informed consent
- No health problem preventing measurement in the tibial and peroneal nerve regions
Key exclusion criteria (5 listed)
- Diagnosed neurological disease
- Lower extremity musculoskeletal injury, previous surgery, or acute pain
- Diabetes, peripheral neuropathy, or other systemic disease that may affect nerve sensitivity
- Open wound, infection, or skin problem at the measurement site
- Use of analgesic or neurologically active medication that may affect the measurements
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Pressure Pain Threshold of the Tibial Nerve
Time frame: At baseline (single assessment)
Pressure pain threshold measured over the tibial nerve region using a digital algometer. Three measurements will be obtained and the mean value will be used for analysis.
Pressure Pain Threshold of the Common Peroneal Nerve
Time frame: At baseline (single assessment)
Pressure pain threshold measured over the common peroneal nerve region using a digital algometer. Three measurements will be obtained and the mean value will be used for analysis.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Apr 2026.
- Individual participant dataSharing planned: No. No individual participant data will be shared. The study involves a relatively small single-center sample of university students, and data sharing could increase the risk of participant re-identification. Results will be reported in aggregate form only, in accordance with ethical approval, informed consent, and applicable data protection regulations.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sümeyye Akçay principal investigator
Fenerbahçe University
Duygu Aktar Reyhanioğlu, Asst. Prof. study chair
Fenerbahçe University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of University Students and Health-related Lifestyle Factors, run by Fenerbahce University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 6 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pressure Pain Threshold of the Tibial Nerve (time frame: At baseline (single assessment)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Apr 2026.