StrokeNCT07512388
Acceptance and Commitment Therapy for Post-Stroke Adjustment Via Telerehabilitation
A study testing Acceptance and Commitment Therapy in people with Stroke and Psychological Flexibility, run by University of East Anglia at 1 site in United Kingdom.
Trial summary
A stroke can affect someone physically and emotionally. There are more than 1.3 million stroke survivors in the UK, so it is important the right support is available. Acceptance and commitment therapy is a psychological therapy that helps people adjust to new circumstances. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Stroke, Psychological Flexibility, Acceptance and Commitment Therapy
- What is being tested?
- Acceptance and Commitment Therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 5 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 4 Sep 2025to 22 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Suffered a stroke over three months ago.
- No other neurological illness.
- Not currently receiving any psychological intervention.
- No severe communication difficulties.
- No severe cognitive impairments.
- No current or historical suicidal ideation/self-harming behaviours.
- Not been diagnosed with major long-term health conditions in the last 12 months (except for stroke or trans-ischaemic attack; TIA)
- Access to a device with a camera, stable internet connection and private space
Who cannot join
- Had a TIA without the presence of a stroke.
- No current distress around adjusting to the consequences of stroke.
- Distress of a severity that it cannot be managed safely in a group therapy setting.
Trial locations and contacts
1 site in 1 country.
About this study
A stroke can affect someone physically and emotionally. There are more than 1.3 million stroke survivors in the UK, so it is important the right support is available.
Acceptance and commitment therapy is a psychological therapy that helps people adjust to new circumstances. Studies have found that it is helpful for people with long-term health conditions such as brain injury, chronic pain, and multiple sclerosis. Therefore, we want to assess if this therapy can help people adjust to life after a stroke.
Read more
To assess this, we are looking for adults over 18 who have:
- Had a stroke over three months ago.
- No other neurological illness.
- No severe cognitive or communication difficulties.
- Been discharged from all rehabilitation programmes.
- No severe psychological disorder.
- Not been diagnosed with a major health condition in the last 12 months.
- Access to a device with a camera, an internet connection and private space for video calls.
Participants will:
- Complete a weekly questionnaire for up to seven weeks on acceptance and action.
- Complete a second questionnaire at week 7 on mood, what is important to participants and how the stroke has affected their life.
- Attend an eight-week online group of acceptance and commitment therapy. Sessions are weekly for 90 minutes, including breaks. Participants will repeat the questionnaire.
- Give feedback after therapy ends and repeat the questionnaires.
- Repeat the questionnaires after three and six months. Participants will be reminded to complete the online questionnaires and can take breaks as needed.
At the end of the study, participants will have a debrief call to discuss details of the study.
Participants will get a £10 Amazon gift card to thank them for taking part.
- Being tested
- Acceptance and Commitment Therapy
- Keywords
- Stroke, acceptance and commitment therapy, ACT, psychological flexibility, wellbeing
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Acceptance and Commitment TherapyOther
Also called ACT
8 weeks of Acceptance and Commitment Therapy delivered as a group intervention via telerehabilitation (online, video call).
| Study group | Role | What they receive |
|---|---|---|
| Acceptance and Commitment Therapy | Experimental | 8-week ACT group intervention. Receives: Other: Acceptance and Commitment Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Psychological flexibility (CompACT-10)
Data collected using self-report measure (CompACT-10). Questionnaire completed online, via a link. Data collected weekly during baseline phase (up to 7 weeks) and intervention phase (8 weeks).
Measured: From baseline to end of intervention (13-15 weeks dependent on baseline length allocated).
Psychological Flexibility (CompACT-10)
Data collected using self-report measure (CompACT-10). Questionnaire completed online, via a link. Data collected 6 months after intervention ends.
Measured: 6 months post-intervention.
Secondary outcomes (13)
Psychological Flexibility (CompACT-10)
Data collected using self-report measure (CompACT-10). Questionnaire completed online, via a link. Data collected 3 months after intervention ends.
Measured: 3 months post-intervention.
Psychological Distress (CORE-10)
Data collected using self-report measure (CORE-10). Questionnaire completed online, via a link. Data collected immediately before and after intervention.
Measured: Start of intervention and 8 weeks later (after intervention ends)
Psychological Distress (CORE-10)
Data collected using self-report measure (CORE-10). Questionnaire completed online, via a link. Data collected 3 months after intervention ends.
Measured: 3 months post-intervention
Psychological Distress (CORE-10)
Data collected using self-report measure (CORE-10). Questionnaire completed online, via a link. Data collected 6 months after intervention ends.
Measured: 6 months post-intervention
Stroke Specific Quality of Life (SSQoL-12)
Data collected using self-report measure (SSQoL-12). Questionnaire completed online, via a link. Data collected immediately before and after 8 week intervention.
Measured: Start of intervention and post 8-week intervention.
Stroke Specific Quality of Life (SSQoL-12)
Data collected using self-report measure (SSQoL-12). Questionnaire completed online, via a link. Data collected 3 months post-intervention.
Measured: 3 months post-intervention
Stroke Specific Quality of Life (SSQoL-12)
Data collected using self-report measure (SSQoL-12). Questionnaire completed online, via a link. Data collected 6 months post-intervention.
Measured: 6 months post-intervention
Independence/Participation (CIQ-15)
Data collected using self-report measure (CIQ-15). Questionnaire completed online, via a link. Data collected 3 months post-intervention.
Measured: 3 months post-intervention
Independence/Participation (CIQ-15)
Data collected using self-report measure (CIQ-15). Questionnaire completed online, via a link. Data collected 6 months post-intervention.
Measured: 6 months post-intervention
Independence/Participation (CIQ-15)
Data collected using self-report measure (CIQ-15). Questionnaire completed online, via a link. Data collected immediately before and after 8 week intervention.
Measured: 8 weeks (before and after intervention).
Wellbeing (SWEMWBS)
Data collected using self-report measure (SWEMWBS). Questionnaire completed online, via a link. Data collected 3 months post-intervention.
Measured: 3 months post-intervention
Wellbeing (SWEMWBS)
Data collected using self-report measure (SWEMWBS). Questionnaire completed online, via a link. Data collected 6 months post-intervention.
Measured: 6 months post-intervention
Wellbeing (SWEMWBS)
Data collected using self-report measure (SWEMWBS). Questionnaire completed online, via a link. Data collected immediately before and after 8 week intervention.
Measured: 8 weeks (before and after intervention)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Apr 2026
- Study start4 Sep 2025
- Primary completion22 Jun 2026
- Study completion22 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 5 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of East Anglia
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07512388
- Sponsor's protocol ID
- 348067
- Status last verified
- Mar 2026
- First submitted
- 25 Mar 2026
- Last updated
- 19 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Acceptance and Commitment Therapy for Post-Stroke Adjustment Via Telerehabilitation
- ClinicalTrials.gov ID
- NCT07512388
- Acronym / sponsor ID
- 348067
- Keywords
- Stroke, acceptance and commitment therapy, ACT, psychological flexibility, wellbeing
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 5 participants (actual)
- Lead sponsor
- University of East AngliaUniversity, hospital or other
- Study start
- 4 Sep 2025 (actual)
- Primary completion
- 22 Jun 2026 (actual)
- Study completion
- 22 Jun 2026 (actual)
- First posted
- 6 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A stroke can affect someone physically and emotionally. There are more than 1.3 million stroke survivors in the UK, so it is important the right support is available.
Acceptance and commitment therapy is a psychological therapy that helps people adjust to new circumstances. Studies have found that it is helpful for people with long-term health conditions such as brain injury, chronic pain, and multiple sclerosis. Therefore, we want to assess if this therapy can help people adjust to life after a stroke.
To assess this, we are looking for adults over 18 who have:
- Had a stroke over three months ago.
- No other neurological illness.
- No severe cognitive or communication difficulties.
- Been discharged from all rehabilitation programmes.
- No severe psychological disorder.
- Not been diagnosed with a major health condition in the last 12 months.
- Access to a device with a camera, an internet connection and private space for video calls.
Participants will:
- Complete a weekly questionnaire for up to seven weeks on acceptance and action.
- Complete a second questionnaire at week 7 on mood, what is important to participants and how the stroke has affected their life.
- Attend an eight-week online group of acceptance and commitment therapy. Sessions are weekly for 90 minutes, including breaks. Participants will repeat the questionnaire.
- Give feedback after therapy ends and repeat the questionnaires.
- Repeat the questionnaires after three and six months. Participants will be reminded to complete the online questionnaires and can take breaks as needed.
At the end of the study, participants will have a debrief call to discuss details of the study.
Participants will get a £10 Amazon gift card to thank them for taking part.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Acceptance and Commitment Therapy | Experimental | Other: Acceptance and Commitment Therapy8-week ACT group intervention. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Suffered a stroke over three months ago.
- No other neurological illness.
- Not currently receiving any psychological intervention.
- No severe communication difficulties.
- No severe cognitive impairments.
Key exclusion criteria (3 listed)
- Had a TIA without the presence of a stroke.
- No current distress around adjusting to the consequences of stroke.
- Distress of a severity that it cannot be managed safely in a group therapy setting.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Acceptance and Commitment TherapyAlso: ACT8 weeks of Acceptance and Commitment Therapy delivered as a group intervention via telerehabilitation (online, video call). | Other | Acceptance and Commitment Therapy |
Primary outcome
Psychological flexibility (CompACT-10)
Time frame: From baseline to end of intervention (13-15 weeks dependent on baseline length allocated).
Data collected using self-report measure (CompACT-10). Questionnaire completed online, via a link. Data collected weekly during baseline phase (up to 7 weeks) and intervention phase (8 weeks).
Psychological Flexibility (CompACT-10)
Time frame: 6 months post-intervention.
Data collected using self-report measure (CompACT-10). Questionnaire completed online, via a link. Data collected 6 months after intervention ends.
13 secondary outcomes
Psychological Flexibility (CompACT-10)
Time frame: 3 months post-intervention.
Psychological Distress (CORE-10)
Time frame: Start of intervention and 8 weeks later (after intervention ends)
Psychological Distress (CORE-10)
Time frame: 3 months post-intervention
Psychological Distress (CORE-10)
Time frame: 6 months post-intervention
Stroke Specific Quality of Life (SSQoL-12)
Time frame: Start of intervention and post 8-week intervention.
Stroke Specific Quality of Life (SSQoL-12)
Time frame: 3 months post-intervention
Stroke Specific Quality of Life (SSQoL-12)
Time frame: 6 months post-intervention
Independence/Participation (CIQ-15)
Time frame: 3 months post-intervention
Independence/Participation (CIQ-15)
Time frame: 6 months post-intervention
Independence/Participation (CIQ-15)
Time frame: 8 weeks (before and after intervention).
Wellbeing (SWEMWBS)
Time frame: 3 months post-intervention
Wellbeing (SWEMWBS)
Time frame: 6 months post-intervention
Wellbeing (SWEMWBS)
Time frame: 8 weeks (before and after intervention)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Acceptance and Commitment Therapy in people with Stroke and Psychological Flexibility, run by University of East Anglia at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Psychological flexibility (CompACT-10) (time frame: From baseline to end of intervention (13-15 weeks dependent on baseline length allocated).). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Aug 2026.