Benign Prostatic HyperplasiaNCT07513896
Factors Predicting The Success of Ejaculation Sparing Transurethral Resection of Prostate in Benign Prostatic Hyperplasia Patients
A study testing ejaculatory preserving TURP in people with Benign Prostatic Hyperplasia and Ejaculation, run by Ain Shams University at 1 site in Egypt.
Trial summary
evaluate the factors predicting the success of ejaculation-sparing TURP in patients with BPH after surgery, in terms of voiding improvement and preserved ejaculation post-operatively. Read more about this study
- Who is it for?
- Any age, men only
- Conditions the study is for
- Benign Prostatic Hyperplasia, Ejaculation
- What is being tested?
- ejaculatory preserving TURP
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 108 participants
- Where
- 1 siteEgypt
- Study dates
- 12 Apr 2025to 25 Jan 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- Men only
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- sexually active male patient with normal ejaculatory function
- upper urinary tract affection and renal insufficiency.
- Chronic Urinary Retention
- Patients with failed medical therapy.
- Patients not compliant to medical treatment
- Patients with recurrent hematuria or recurrent lower urinary tract infections
Who cannot join
- Patients with an anterior urethral stricture
- Patients with history of urethral operations
- Patients with previous prostatic surgery
- Patients with neurological disorders
- Non sexually active patients
Trial locations and contacts
1 site in 1 country.
About this study
evaluate the factors predicting the success of ejaculation-sparing TURP in patients with BPH after surgery, in terms of voiding improvement and preserved ejaculation post-operatively.
- Conditions
- Benign Prostatic Hyperplasia, Ejaculation
- Being tested
- ejaculatory preserving TURP
- Medical subject headings
- Prostatic Hyperplasia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ejaculatory preserving TURPProcedure or surgery
In our study, we performed an EP-TURP technique, which is adopted in our institute and involves the preservation of 1 cm of urethral mucosa all around the verumontanum, including the prostatic apical urethral mucosa, with adequate resection of the prostatic adenoma, including the apical prostatic tissue, which was resected lateral to the spared urethral mucosa to ensure adequate management of the outflow obstruction. (8). Bi-polar TURP was performed using a 26 Fr. Resectoscope (Karl Storz, Tuttlingen, Germany) and Karl Storz- AUTOCON® IV.
Intraoperative cystoscopic evaluation and documentation of the prostatic anatomy were done. SML was measured cystoscopically using a 22 Fr sheath with centimeter markings. Operative time, perioperative complications, catheterization duration, and hospital stay were recorded. Urethral catheter removal was planned after 24-48 hours unless prolonged catheterization was clinically indicated.
| Study group | Role | What they receive |
|---|---|---|
| patients with BPH underwent Ejaculatory preserving TURP | Experimental | Not described Receives: Procedure: ejaculatory preserving TURP |
What is being measured
The primary outcome is the main question the study is designed to answer.
Preservation of antegrade ejaculation at 3 months
The primary outcome was to assess the post operative ejaculation at 3 months using Male Sexual Health Questionnaire for ejaculatory dysfunction short form (MSHQ-Ej.D-SF).
Measured: 3 months
Secondary outcomes (1)
post-operative post-voiding residual volume
Measurement of post-operative post-voiding residual volume by Pelvi-abdominal Ultrasound
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Apr 2026
- Study start12 Apr 2025
- Primary completion12 Dec 2025
- Study completion25 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Benign Prostatic HyperplasiaStudies of the same condition, open and under way.
- More trials run by Ain Shams UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 108 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ain Shams University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07513896
- Sponsor's protocol ID
- FMASU MS 397/2025
- Status last verified
- Apr 2026
- First submitted
- 12 Feb 2026
- Last updated
- 7 Apr 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Publications
2. Tawfik AM, Alloussi S, Ben Rhouma S. (2017). Ejaculation-Sparing Techniques in TURP for Benign Prostatic Hyperplasia: A Systematic Review and Meta-analysis. Journal of Urology; 197(4): 1050-1057.
Study at a glance
From the registry record, last updated by the sponsor on 7 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Factors Predicting The Success of Ejaculation Sparing Transurethral Resection of Prostate in Benign Prostatic Hyperplasia Patients
- ClinicalTrials.gov ID
- NCT07513896
- Acronym / sponsor ID
- FMASU MS 397/2025
- Conditions
- Benign Prostatic Hyperplasia, Ejaculation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 108 participants (actual)
- Lead sponsor
- Ain Shams UniversityUniversity, hospital or other
- Study start
- 12 Apr 2025 (actual)
- Primary completion
- 12 Dec 2025 (actual)
- Study completion
- 25 Jan 2026 (actual)
- First posted
- 7 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
evaluate the factors predicting the success of ejaculation-sparing TURP in patients with BPH after surgery, in terms of voiding improvement and preserved ejaculation post-operatively.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| patients with BPH underwent Ejaculatory preserving TURP | Experimental | Procedure: ejaculatory preserving TURP |
Who may qualify
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (6 listed)
- sexually active male patient with normal ejaculatory function
- upper urinary tract affection and renal insufficiency.
- Chronic Urinary Retention
- Patients with failed medical therapy.
- Patients not compliant to medical treatment
Key exclusion criteria (5 listed)
- Patients with an anterior urethral stricture
- Patients with history of urethral operations
- Patients with previous prostatic surgery
- Patients with neurological disorders
- Non sexually active patients
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ejaculatory preserving TURPIn our study, we performed an EP-TURP technique, which is adopted in our institute and involves the preservation of 1 cm of urethral mucosa all around the verumontanum, including the prostatic apical urethral mucosa, with adequate resection of the prostatic adenoma, including the apical prostatic tissue, which was resected lateral to the spared urethral mucosa to ensure adequate management of the outflow obstruction. (8). Bi-polar TURP was performed using a 26 Fr. Resectoscope (Karl Storz, Tuttlingen, Germany) and Karl Storz- AUTOCON® IV. Intraoperative cystoscopic evaluation and documentation of the prostatic anatomy were done. SML was measured cystoscopically using a 22 Fr sheath with centimeter markings. Operative time, perioperative complications, catheterization duration, and hospital stay were recorded. Urethral catheter removal was planned after 24-48 hours unless prolonged catheterization was clinically indicated. | Procedure or surgery | patients with BPH underwent Ejaculatory preserving TURP |
Primary outcome
Preservation of antegrade ejaculation at 3 months
Time frame: 3 months
The primary outcome was to assess the post operative ejaculation at 3 months using Male Sexual Health Questionnaire for ejaculatory dysfunction short form (MSHQ-Ej.D-SF).
1 secondary outcome
post-operative post-voiding residual volume
Time frame: 3 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Apr 2026.
- Results publication2. Tawfik AM, Alloussi S, Ben Rhouma S. (2017). Ejaculation-Sparing Techniques in TURP for Benign Prostatic Hyperplasia: A Systematic Review and Meta-analysis. Journal of Urology; 197(4): 1050-1057.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ejaculatory preserving TURP in people with Benign Prostatic Hyperplasia and Ejaculation, run by Ain Shams University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Preservation of antegrade ejaculation at 3 months (time frame: 3 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07513896, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Apr 2026.