SpondylolisthesisNCT07514806
Ultrasound-Guided Erector Spinae Plane Block for Postoperative Pain Control in Lumbar Spondylolisthesis Surgery
A study testing Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block in people with Spondylolisthesis and Analgesia, Postoperative, run by Bangladesh Medical University at 1 site in Bangladesh.
Trial summary
This clinical trial aims to evaluate the effectiveness of ultrasound-guided erector spinae plane (ESP) block as an adjunct to general anesthesia for managing postoperative pain in patients undergoing lumbar spondylolisthesis surgery. Read more about this study
- Who is it for?
- Ages 18 to 64 years
- Conditions the study is for
- Spondylolisthesis, Analgesia, Postoperative, ESPB
- What is being tested?
- Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteBangladesh
- Study dates
- 1 Jun 2024to 30 Nov 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 64 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patient undergoing lumbar spondylolisthesis surgery.
- Elective procedures.
- Age between 18 to 64 years.
- American Society of Anaesthesiologists (ASA) physical status 1 and 2.
Who cannot join
- Patient refusal.
- Body Mass Index (BMI) >35 kg/m2
- Coagulopathy or bleeding disorders.
- Allergy to any of the study drugs.
- Substance abuse or dependence or previous history of opioid addiction.
- Patients with central nervous system disease, severe cardiovascular system disease, hepatic disease or renal disease.
- Local infection or inflammation at the site of block placement.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Estimation of Intraoperative Anaesthetic Drug Requirement in General Anaesthesia With or Without Erector Spinae Plane Block in Lumbar Spondylolisthesis Surgery
This clinical trial aims to evaluate the effectiveness of ultrasound-guided erector spinae plane (ESP) block as an adjunct to general anesthesia for managing postoperative pain in patients undergoing lumbar spondylolisthesis surgery. The study will compare two groups: one receiving general anesthesia with ESP block (intervention group) and the other receiving general anesthesia alone (control group). The primary objective is to assess postoperative pain relief, opioid consumption, and hemodynamic stability. Secondary outcomes include adverse events and recovery quality. This trial will provide valuable insights into the efficacy of ESP block in improving recovery outcomes and reducing opioid use in spine surgery patients.
Read the detailed description
This study is designed as a quasi-experimental trial to investigate the efficacy of the ultrasound-guided erector spinae plane (ESP) block in combination with general anesthesia for postoperative pain management in patients undergoing lumbar spondylolisthesis surgery. This clinical trial will recruit 50 adult patients scheduled for elective lumbar spine surgery, who are assigned to either the intervention or control group.
Intervention Group (Group B): Patients will receive ultrasound-guided ESP block as an adjunct to standard general anesthesia.
Control Group (Group A): Patients will receive general anesthesia without the erector spinae plane (ESP) block.
The trial will evaluate pain control (measured by Visual Analogue Scale [VAS] scores), opioid consumption, and hemodynamic parameters (such as heart rate, blood pressure, and oxygen saturation). Additionally, postoperative recovery quality, the incidence of adverse events, and any potential complications associated with the erector spinae plane (ESP) block will be monitored and compared between groups.
This trial also aims to assess whether the use of the erector spinae plane (ESP) block can reduce opioid consumption, improve hemodynamic stability, and enhance recovery quality in the postoperative period.
The study will be conducted at Bangladesh Medical University (BMU), Dhaka, with all ethical considerations adhered to, and informed consent will be obtained from all participants before enrollment. Participants will be followed for 24 hours post-surgery, with monitoring at several time points to assess the primary and secondary outcomes.
The results of this study are expected to provide valuable insights into the effectiveness of the erector spinae plane (ESP block) in improving surgical outcomes, reducing opioid use, and enhancing recovery after lumbar spine surgery.
- Conditions
- Spondylolisthesis, Analgesia, Postoperative, ESPB
- Being tested
- Control Group: General Anesthesia Without Erector Spinae Plane Block, Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block
- Keywords
- anaesthetic drug requirement, lumber spondylolisthesis surgery, Erector Spinae Plane Block
- Medical subject headings
- Spondylolisthesis, Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Control Group: General Anesthesia Without Erector Spinae Plane BlockProcedure or surgery
Intervention Type: Drug - General Anesthesia Description: Patients will receive general anesthesia using standard anesthetic agents (e.g., propofol, fentanyl, and isoflurane) without the addition of a regional block. No erector spinae plane (ESP) block will be performed.
Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane BlockProcedure or surgery
Description: Patients will receive general anesthesia in combination with an ultrasound-guided erector spinae plane (ESP) block. The ESP block will be performed at the L3-L5 vertebral level using a 22-gauge needle, with 20 mL of 0.25% bupivacaine and 5 mg dexamethasone administered bilaterally under sterile conditions.
| Study group | Role | What they receive |
|---|---|---|
| Control Group: General Anesthesia Without Erector Spinae Plane Block | Active comparator | Control Group: General Anesthesia Without Erector Spinae Plane Block In this group, patients will receive standard general anesthesia without the addition of an ultrasound-guided erector spinae plane (ESP) block. This arm will serve as the comparison group to assess the impact of the ESP block on postoperative pain and recovery outcomes. Receives: Procedure: Control Group: General Anesthesia Without Erector Spinae Plane Block |
| Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block | Experimental | Intervention Group: General Anaesthesia With Ultrasound-Guided Erector Spinae Plane (ESP) Block In this group, patients will receive general anaesthesia in combination with an ultrasound-guided erector spinae plane block. The aim is to evaluate whether adding the ESP block improves postoperative pain control, reduces opioid consumption, and enhances hemodynamic stability during and after lumbar spondylolisthesis surgery. Receives: Procedure: Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Intraoperative Opioid Requirements (Fentanyl in micrograms)
The total amount of opioid (fentanyl in microgram) administered during surgery. The goal is to evaluate the opioid consumption required to maintain adequate analgesia during the procedure.
Measured: Throughout the duration of surgery.
Intraoperative Inhalational Anaesthetic (Isoflurane in ml/hour) Agent Requirements
Description: The total consumption of inhalational anesthetic agents (Isoflurane in ml/hour) during the surgical procedure. This measure will help assess the inhalational anaesthetic requirement between groups.
Measured: Throughout the duration of surgery
Intraoperative Muscle Relaxant (vecuronium in mg) Requirements
The total dose of muscle relaxant (vecuronium, in mg) is administered to maintain muscle relaxation during surgery. This will be compared between the two groups.
Measured: Throughout the duration of surgery
Secondary outcomes (4)
Intraoperative heart rate (HR)
Measured: Recorded at 15-minute intervals during the surgery
Intraoperative Systolic Blood Pressure (mmHg)
Measured: Recorded at 15-minute intervals during the surgery
Intraoperative diastolic blood pressure (mmHg)
Measured: Recorded at 15-minute intervals during the surgery
Intraoperative Mean Arterial Pressure (mmHg)
Measured: Recorded at 15-minute intervals during the surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Apr 2026
- Study start1 Jun 2024
- Primary completion30 Nov 2024
- Study completion30 Nov 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (52)Papers the sponsor has linked to this study.
- Other trials for SpondylolisthesisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Bangladesh Medical University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Kazi Mahzabin Arin, Bangladesh Medical University
- Investigators
- AKM Akhtaruzzaman, MD, Study director, Bangladesh Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07514806
- Sponsor's protocol ID
- 4975
- Status last verified
- Apr 2026
- First submitted
- 31 Mar 2026
- Last updated
- 9 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Zhang S, Han X, Zhou D, Sun M, Cang J, Miao C, Liang C. The effects of erector spinae plane block on perioperative opioid consumption and rehabilitation in video assisted thoracic surgery. BMC Anesthesiol. 2021 Dec 10;21(1):313. doi: 10.1186/s12871-021-01536-x.
PubMed 34893026Yang HM, Choi YJ, Kwon HJ, O J, Cho TH, Kim SH. Comparison of injectate spread and nerve involvement between retrolaminar and erector spinae plane blocks in the thoracic region: a cadaveric study. Anaesthesia. 2018 Oct;73(10):1244-1250. doi: 10.1111/anae.14408. Epub 2018 Aug 16.
PubMed 30113699Wilson AA, Schmid AM, Pestana P Jr, Tubog TD. Erector Spinae Plane Block on Postoperative Pain and Opioid Consumption After Lumbar Spine Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials. J Perianesth Nurs. 2024 Feb;39(1):122-131. doi: 10.1016/j.jopan.2023.06.003. Epub 2023 Sep 23.
PubMed 37747377Willard FH, Vleeming A, Schuenke MD, Danneels L, Schleip R. The thoracolumbar fascia: anatomy, function and clinical considerations. J Anat. 2012 Dec;221(6):507-36. doi: 10.1111/j.1469-7580.2012.01511.x. Epub 2012 May 27.
PubMed 22630613Ueshima H, Inagaki M, Toyone T, Otake H. Efficacy of the Erector Spinae Plane Block for Lumbar Spinal Surgery: A Retrospective Study. Asian Spine J. 2019 Apr;13(2):254-257. doi: 10.31616/asj.2018.0114. Epub 2018 Nov 15.
PubMed 30424594Tulgar S, Kapakli MS, Senturk O, Selvi O, Serifsoy TE, Ozer Z. Evaluation of ultrasound-guided erector spinae plane block for postoperative analgesia in laparoscopic cholecystectomy: A prospective, randomized, controlled clinical trial. J Clin Anesth. 2018 Sep;49:101-106. doi: 10.1016/j.jclinane.2018.06.019. Epub 2018 Jun 15.
PubMed 29913392Tulgar S, Thomas DT, Deveci U. Erector spinae plane block provides sufficient surgical anesthesia for ileostomy closure in a high-risk patient. J Clin Anesth. 2018 Aug;48:2-3. doi: 10.1016/j.jclinane.2018.04.001. Epub 2018 Apr 11. No abstract available.
PubMed 29655135Tulgar S, Ahiskalioglu A, De Cassai A, Gurkan Y. Efficacy of bilateral erector spinae plane block in the management of pain: current insights. J Pain Res. 2019 Aug 27;12:2597-2613. doi: 10.2147/JPR.S182128. eCollection 2019.
PubMed 31695476Sullivan TR, Kanda P, Gagne S, Costache I. Harlequin Syndrome Associated with Erector Spinae Plane Block. Anesthesiology. 2019 Sep;131(3):665. doi: 10.1097/ALN.0000000000002733. No abstract available.
PubMed 31021847Soro Domingo M, Belda Nacher FJ, Aguilar Aguilar G, Ferrandis Comes R, Garcia-Raimundo M, Martinez Pons V. [Preoxygenation for anesthesia]. Rev Esp Anestesiol Reanim. 2004 Jun-Jul;51(6):322-7. Spanish.
PubMed 15303533Weinstein JN, Lurie JD, Tosteson TD, Hanscom B, Tosteson AN, Blood EA, Birkmeyer NJ, Hilibrand AS, Herkowitz H, Cammisa FP, Albert TJ, Emery SE, Lenke LG, Abdu WA, Longley M, Errico TJ, Hu SS. Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis. N Engl J Med. 2007 May 31;356(22):2257-70. doi: 10.1056/NEJMoa070302.
PubMed 17538085Schwartz RH, Urits I, Viswanath O, Urman RD, Kaye AD, Eskander JP. Successful combination of thoracodorsal interfascial plane block and erector spinae pain block for peri-operative pain control after lumbar laminectomy. J Clin Anesth. 2020 Jun;62:109705. doi: 10.1016/j.jclinane.2020.109705. Epub 2020 Jan 11. No abstract available.
PubMed 31935574Sachdev D, Mamikunian G, Kia C, Zhou H. Narrative review: erector spinae block in spine surgery. J Spine Surg. 2023 Dec 25;9(4):454-462. doi: 10.21037/jss-23-14. Epub 2023 Dec 20.
PubMed 38196733Rizkalla JM, Holderread B, Awad M, Botros A, Syed IY. The erector spinae plane block for analgesia after lumbar spine surgery: A systematic review. J Orthop. 2021 Feb 18;24:145-150. doi: 10.1016/j.jor.2021.02.006. eCollection 2021 Mar-Apr.
PubMed 33716419Peker K, Akcaboy ZN, Aydin G, Gencay I, Sahin AT, Kocak YF, Peker SA. The Effect of Erector Spinae Plane Block on Laparoscopic Cholecystectomy Anesthesia: Analysis of Opioid Consumption, Sevoflurane Consumption, and Cost. J Laparoendosc Adv Surg Tech A. 2020 Jul;30(7):725-729. doi: 10.1089/lap.2019.0809. Epub 2020 Feb 5.
PubMed 32023174
Study at a glance
From the registry record, last updated by the sponsor on 9 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Estimation of Intraoperative Anaesthetic Drug Requirement in General Anaesthesia With or Without Erector Spinae Plane Block in Lumbar Spondylolisthesis Surgery
- ClinicalTrials.gov ID
- NCT07514806
- Acronym / sponsor ID
- 4975
- Conditions
- Spondylolisthesis, Analgesia, Postoperative, ESPB
- Keywords
- anaesthetic drug requirement, lumber spondylolisthesis surgery, Erector Spinae Plane Block
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Bangladesh Medical UniversityUniversity, hospital or other
- Study start
- 1 Jun 2024 (actual)
- Primary completion
- 30 Nov 2024 (actual)
- Study completion
- 30 Nov 2024 (actual)
- First posted
- 7 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This clinical trial aims to evaluate the effectiveness of ultrasound-guided erector spinae plane (ESP) block as an adjunct to general anesthesia for managing postoperative pain in patients undergoing lumbar spondylolisthesis surgery. The study will compare two groups: one receiving general anesthesia with ESP block (intervention group) and the other receiving general anesthesia alone (control group). The primary objective is to assess postoperative pain relief, opioid consumption, and hemodynamic stability. Secondary outcomes include adverse events and recovery quality. This trial will provide valuable insights into the efficacy of ESP block in improving recovery outcomes and reducing opioid use in spine surgery patients.
Detailed description
This study is designed as a quasi-experimental trial to investigate the efficacy of the ultrasound-guided erector spinae plane (ESP) block in combination with general anesthesia for postoperative pain management in patients undergoing lumbar spondylolisthesis surgery. This clinical trial will recruit 50 adult patients scheduled for elective lumbar spine surgery, who are assigned to either the intervention or control group.
Intervention Group (Group B): Patients will receive ultrasound-guided ESP block as an adjunct to standard general anesthesia.
Control Group (Group A): Patients will receive general anesthesia without the erector spinae plane (ESP) block.
The trial will evaluate pain control (measured by Visual Analogue Scale [VAS] scores), opioid consumption, and hemodynamic parameters (such as heart rate, blood pressure, and oxygen saturation). Additionally, postoperative recovery quality, the incidence of adverse events, and any potential complications associated with the erector spinae plane (ESP) block will be monitored and compared between groups.
This trial also aims to assess whether the use of the erector spinae plane (ESP) block can reduce opioid consumption, improve hemodynamic stability, and enhance recovery quality in the postoperative period.
The study will be conducted at Bangladesh Medical University (BMU), Dhaka, with all ethical considerations adhered to, and informed consent will be obtained from all participants before enrollment. Participants will be followed for 24 hours post-surgery, with monitoring at several time points to assess the primary and secondary outcomes.
The results of this study are expected to provide valuable insights into the effectiveness of the erector spinae plane (ESP block) in improving surgical outcomes, reducing opioid use, and enhancing recovery after lumbar spine surgery.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control Group: General Anesthesia Without Erector Spinae Plane Block | Active comparator | Procedure: Control Group: General Anesthesia Without Erector Spinae Plane BlockControl Group: General Anesthesia Without Erector Spinae Plane Block In this group, patients will receive standard general anesthesia without the addition of an ultrasound-guided erector spinae plane (ESP) block. This arm will serve as the comparison group to assess the impact of the ESP block on postoperative pain and recovery outcomes. |
| Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block | Experimental | Procedure: Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane BlockIntervention Group: General Anaesthesia With Ultrasound-Guided Erector Spinae Plane (ESP) Block In this group, patients will receive general anaesthesia in combination with an ultrasound-guided erector spinae plane block. The aim is to evaluate whether adding the ESP block improves postoperative pain control, reduces opioid consumption, and enhances hemodynamic stability during and after lumbar spondylolisthesis surgery. |
Who may qualify
- Ages
- 18 to 64 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Patient undergoing lumbar spondylolisthesis surgery.
- Elective procedures.
- Age between 18 to 64 years.
- American Society of Anaesthesiologists (ASA) physical status 1 and 2.
Key exclusion criteria (7 listed)
- Patient refusal.
- Body Mass Index (BMI) >35 kg/m2
- Coagulopathy or bleeding disorders.
- Allergy to any of the study drugs.
- Substance abuse or dependence or previous history of opioid addiction.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Control Group: General Anesthesia Without Erector Spinae Plane BlockIntervention Type: Drug - General Anesthesia Description: Patients will receive general anesthesia using standard anesthetic agents (e.g., propofol, fentanyl, and isoflurane) without the addition of a regional block. No erector spinae plane (ESP) block will be performed. | Procedure or surgery | Control Group: General Anesthesia Without Erector Spinae Plane Block |
| Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane BlockDescription: Patients will receive general anesthesia in combination with an ultrasound-guided erector spinae plane (ESP) block. The ESP block will be performed at the L3-L5 vertebral level using a 22-gauge needle, with 20 mL of 0.25% bupivacaine and 5 mg dexamethasone administered bilaterally under sterile conditions. | Procedure or surgery | Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block |
Primary outcome
Intraoperative Opioid Requirements (Fentanyl in micrograms)
Time frame: Throughout the duration of surgery.
The total amount of opioid (fentanyl in microgram) administered during surgery. The goal is to evaluate the opioid consumption required to maintain adequate analgesia during the procedure.
Intraoperative Inhalational Anaesthetic (Isoflurane in ml/hour) Agent Requirements
Time frame: Throughout the duration of surgery
Description: The total consumption of inhalational anesthetic agents (Isoflurane in ml/hour) during the surgical procedure. This measure will help assess the inhalational anaesthetic requirement between groups.
Intraoperative Muscle Relaxant (vecuronium in mg) Requirements
Time frame: Throughout the duration of surgery
The total dose of muscle relaxant (vecuronium, in mg) is administered to maintain muscle relaxation during surgery. This will be compared between the two groups.
4 secondary outcomes
Intraoperative heart rate (HR)
Time frame: Recorded at 15-minute intervals during the surgery
Intraoperative Systolic Blood Pressure (mmHg)
Time frame: Recorded at 15-minute intervals during the surgery
Intraoperative diastolic blood pressure (mmHg)
Time frame: Recorded at 15-minute intervals during the surgery
Intraoperative Mean Arterial Pressure (mmHg)
Time frame: Recorded at 15-minute intervals during the surgery
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Apr 2026.
- Background: PubMed 34893026Zhang S, Han X, Zhou D, Sun M, Cang J, Miao C, Liang C. The effects of erector spinae plane block on perioperative opioid consumption and rehabilitation in video assisted thoracic surgery. BMC Anesthesiol. 2021 Dec 10;21(1):313. doi: 10.1186/s12871-021-01536-x.
- Background: PubMed 30113699Yang HM, Choi YJ, Kwon HJ, O J, Cho TH, Kim SH. Comparison of injectate spread and nerve involvement between retrolaminar and erector spinae plane blocks in the thoracic region: a cadaveric study. Anaesthesia. 2018 Oct;73(10):1244-1250. doi: 10.1111/anae.14408. Epub 2018 Aug 16.
- Background: PubMed 37747377Wilson AA, Schmid AM, Pestana P Jr, Tubog TD. Erector Spinae Plane Block on Postoperative Pain and Opioid Consumption After Lumbar Spine Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials. J Perianesth Nurs. 2024 Feb;39(1):122-131. doi: 10.1016/j.jopan.2023.06.003. Epub 2023 Sep 23.
- Background: PubMed 22630613Willard FH, Vleeming A, Schuenke MD, Danneels L, Schleip R. The thoracolumbar fascia: anatomy, function and clinical considerations. J Anat. 2012 Dec;221(6):507-36. doi: 10.1111/j.1469-7580.2012.01511.x. Epub 2012 May 27.
- Background: PubMed 30424594Ueshima H, Inagaki M, Toyone T, Otake H. Efficacy of the Erector Spinae Plane Block for Lumbar Spinal Surgery: A Retrospective Study. Asian Spine J. 2019 Apr;13(2):254-257. doi: 10.31616/asj.2018.0114. Epub 2018 Nov 15.
- Background: PubMed 29913392Tulgar S, Kapakli MS, Senturk O, Selvi O, Serifsoy TE, Ozer Z. Evaluation of ultrasound-guided erector spinae plane block for postoperative analgesia in laparoscopic cholecystectomy: A prospective, randomized, controlled clinical trial. J Clin Anesth. 2018 Sep;49:101-106. doi: 10.1016/j.jclinane.2018.06.019. Epub 2018 Jun 15.
- Background: PubMed 29655135Tulgar S, Thomas DT, Deveci U. Erector spinae plane block provides sufficient surgical anesthesia for ileostomy closure in a high-risk patient. J Clin Anesth. 2018 Aug;48:2-3. doi: 10.1016/j.jclinane.2018.04.001. Epub 2018 Apr 11. No abstract available.
- Background: PubMed 31695476Tulgar S, Ahiskalioglu A, De Cassai A, Gurkan Y. Efficacy of bilateral erector spinae plane block in the management of pain: current insights. J Pain Res. 2019 Aug 27;12:2597-2613. doi: 10.2147/JPR.S182128. eCollection 2019.
- Background: PubMed 31021847Sullivan TR, Kanda P, Gagne S, Costache I. Harlequin Syndrome Associated with Erector Spinae Plane Block. Anesthesiology. 2019 Sep;131(3):665. doi: 10.1097/ALN.0000000000002733. No abstract available.
- Background: PubMed 15303533Soro Domingo M, Belda Nacher FJ, Aguilar Aguilar G, Ferrandis Comes R, Garcia-Raimundo M, Martinez Pons V. [Preoxygenation for anesthesia]. Rev Esp Anestesiol Reanim. 2004 Jun-Jul;51(6):322-7. Spanish.
- Background: PubMed 17538085Weinstein JN, Lurie JD, Tosteson TD, Hanscom B, Tosteson AN, Blood EA, Birkmeyer NJ, Hilibrand AS, Herkowitz H, Cammisa FP, Albert TJ, Emery SE, Lenke LG, Abdu WA, Longley M, Errico TJ, Hu SS. Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis. N Engl J Med. 2007 May 31;356(22):2257-70. doi: 10.1056/NEJMoa070302.
- Background: PubMed 31935574Schwartz RH, Urits I, Viswanath O, Urman RD, Kaye AD, Eskander JP. Successful combination of thoracodorsal interfascial plane block and erector spinae pain block for peri-operative pain control after lumbar laminectomy. J Clin Anesth. 2020 Jun;62:109705. doi: 10.1016/j.jclinane.2020.109705. Epub 2020 Jan 11. No abstract available.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
AKM Akhtaruzzaman, MD study director
Bangladesh Medical University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block in people with Spondylolisthesis and Analgesia, Postoperative, run by Bangladesh Medical University at 1 site in Bangladesh.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Bangladesh. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Intraoperative Opioid Requirements (Fentanyl in micrograms) (time frame: Throughout the duration of surgery.). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07514806, which also lists 52 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Apr 2026.