Cerebral Palsy (CP)Tele-RehabNCT07518511
Sensory-Enhanced Asynchronous Tele-Rehabilitation Model for Improving Function in Children With Cerebral Palsy
A study testing Sensory-Enhanced Home-based Intensive Program (SE-HIP) and Standard Home Program (SHP) in people with Cerebral Palsy (CP) and Tele-rehabilitation, run by Cairo University at 1 site in Egypt.
Trial summary
PURPOSE: This study evaluated the effectiveness of a Sensory-Enhanced Home-based Intensive Program (SE-HIP), delivered via asynchronous video guidance, compared to a Standard Home Program (SHP) on improving upper limb function in children with cerebral palsy (CP). Read more about this study
- Who is it for?
- Ages 5 to 10 years
- Conditions the study is for
- Cerebral Palsy (CP), Tele-rehabilitation
- What is being tested?
- Sensory-Enhanced Home-based Intensive Program (SE-HIP) and Standard Home Program (SHP)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2026to 31 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 5 to 10 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Mild spasticity (MAS 1 or 1+), independent ambulation (AFOs permitted), and the ability to follow simple instructions
Who cannot join
- Significant fixed deformities, cognitive or sensory impairments hindering participation, uncontrolled epilepsy, or recent interventions like botulinum toxin or orthopedic surgery
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Faculty of Physical Therapy, Cairo University
Giza, Cairo Governorate, 12613
About this study
Official title: Sensory-Enhanced Asynchronous Tele-Rehabilitation Model for Improving Function in Children With Cerebral Palsy: A Randomized Controlled Trial
PURPOSE: This study evaluated the effectiveness of a Sensory-Enhanced Home-based Intensive Program (SE-HIP), delivered via asynchronous video guidance, compared to a Standard Home Program (SHP) on improving upper limb function in children with cerebral palsy (CP).
BACKGROUND: Children with cerebral palsy (CP) often have upper limb (UL) impairments that limit daily life and participation. Intensive, repetitive therapy is crucial, but traditional delivery has limitations. Home-based programs supported by tele-rehabilitation offer increased dosage and accessibility. Asynchronous models delivered via video guidance are flexible but are less studied for intensive upper limb therapy. Sensory processing deficits are common in cerebral palsy; integrating sensory enhancement may augment motor learning. Evidence combining sensory-enhanced intensive upper limb programs delivered asynchronously is lacking.
Read more
HYPOTHESES: The investigators hypothesized that children receiving the Sensory-Enhanced Home-based Intensive Program (SE-HIP) would demonstrate significantly greater improvements in primary upper limb functional outcomes, measured by the Box and Block Test (BBT) and the Nine-Hole Peg Test (NHPT), compared to those receiving the Standard Home Program (SHP).
RESEARCH QUESTION: Does a sensory-enhanced, asynchronous video-guided home program lead to significantly greater improvements in upper limb function (manual dexterity measured by the Box and Block Test (BBT) and the Nine-Hole Peg Test (NHPT)) compared to a standard video-guided home program in children with cerebral palsy (CP)?
- Conditions
- Cerebral Palsy (CP), Tele-rehabilitation
- Being tested
- Sensory-Enhanced Home-based Intensive Program (SE-HIP), Standard Home Program (SHP)
- Medical subject headings
- Cerebral Palsy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sensory-Enhanced Home-based Intensive Program (SE-HIP)Other
Videos include sensory preparation and intensive motor practice delivered asynchronously at home.
Standard Home Program (SHP)Other
Videos cover standard home exercise activities delivered asynchronously at home.
| Study group | Role | What they receive |
|---|---|---|
| Sensory-Enhanced Home-based Intensive Program (SE-HIP) | Experimental | Children receive videos that include sensory preparation and intensive motor practice as part of the Sensory-Enhanced Home-based Intensive Program (SE-HIP). Receives: Other: Sensory-Enhanced Home-based Intensive Program (SE-HIP) |
| Standard Home Program (SHP) | Active comparator | Children receive videos that cover standard activities as part of the Standard Home Program (SHP). Receives: Other: Standard Home Program (SHP) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Nine-Hole Peg Test
Assesses fine manual dexterity (finger dexterity). The patient places and removes nine pegs into a board as quickly as possible.
Measured: Baseline and after 6 weeks of training
Box and Block Test
Assesses gross manual dexterity. The patient moves small wooden blocks across a partition in 60 seconds
Measured: Baseline and after 6 weeks of training
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Apr 2026
- Study start1 Jan 2026
- Primary completion30 Mar 2026
- Study completion31 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Cerebral Palsy (CP)Studies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tamer Mohamed El-Saeed, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07518511
- Sponsor's protocol ID
- P.T.REC/012/006150
- Acronym
- Tele-Rehab
- Status last verified
- Apr 2026
- First submitted
- 31 Mar 2026
- Last updated
- 8 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is currently no plan to share de-identified individual participant data (IPD) from this trial outside the primary research group.
Publications
Kashif M, Albalwi A, Mehdi Kazmi SA, Alharbi AA, Bashir K, Aqeel Aslam M, Ghaffar T. Role of telerehabilitation in the rehabilitation of children with cerebral palsy during COVID-19: A review. Medicine (Baltimore). 2024 Mar 1;103(9):e37214. doi: 10.1097/MD.0000000000037214.
PubMed 38428904Molinaro A, Micheletti S, Pagani F, Garofalo G, Galli J, Rossi A, Fazzi E, Buccino G. Action Observation Treatment in a tele-rehabilitation setting: a pilot study in children with cerebral palsy. Disabil Rehabil. 2022 Apr;44(7):1107-1112. doi: 10.1080/09638288.2020.1793009. Epub 2020 Aug 17.
PubMed 32805150
Study at a glance
From the registry record, last updated by the sponsor on 8 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Sensory-Enhanced Asynchronous Tele-Rehabilitation Model for Improving Function in Children With Cerebral Palsy: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07518511
- Acronym / sponsor ID
- Tele-Rehab / P.T.REC/012/006150
- Conditions
- Cerebral Palsy (CP), Tele-rehabilitation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 30 Mar 2026 (actual)
- Study completion
- 31 Mar 2026 (actual)
- First posted
- 8 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
PURPOSE: This study evaluated the effectiveness of a Sensory-Enhanced Home-based Intensive Program (SE-HIP), delivered via asynchronous video guidance, compared to a Standard Home Program (SHP) on improving upper limb function in children with cerebral palsy (CP).
BACKGROUND: Children with cerebral palsy (CP) often have upper limb (UL) impairments that limit daily life and participation. Intensive, repetitive therapy is crucial, but traditional delivery has limitations. Home-based programs supported by tele-rehabilitation offer increased dosage and accessibility. Asynchronous models delivered via video guidance are flexible but are less studied for intensive upper limb therapy. Sensory processing deficits are common in cerebral palsy; integrating sensory enhancement may augment motor learning. Evidence combining sensory-enhanced intensive upper limb programs delivered asynchronously is lacking.
HYPOTHESES: The investigators hypothesized that children receiving the Sensory-Enhanced Home-based Intensive Program (SE-HIP) would demonstrate significantly greater improvements in primary upper limb functional outcomes, measured by the Box and Block Test (BBT) and the Nine-Hole Peg Test (NHPT), compared to those receiving the Standard Home Program (SHP).
RESEARCH QUESTION: Does a sensory-enhanced, asynchronous video-guided home program lead to significantly greater improvements in upper limb function (manual dexterity measured by the Box and Block Test (BBT) and the Nine-Hole Peg Test (NHPT)) compared to a standard video-guided home program in children with cerebral palsy (CP)?
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Sensory-Enhanced Home-based Intensive Program (SE-HIP) | Experimental | Other: Sensory-Enhanced Home-based Intensive Program (SE-HIP)Children receive videos that include sensory preparation and intensive motor practice as part of the Sensory-Enhanced Home-based Intensive Program (SE-HIP). |
| Standard Home Program (SHP) | Active comparator | Other: Standard Home Program (SHP)Children receive videos that cover standard activities as part of the Standard Home Program (SHP). |
Who may qualify
- Ages
- 5 to 10 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (1 listed)
- Mild spasticity (MAS 1 or 1+), independent ambulation (AFOs permitted), and the ability to follow simple instructions
Key exclusion criteria (1 listed)
- Significant fixed deformities, cognitive or sensory impairments hindering participation, uncontrolled epilepsy, or recent interventions like botulinum toxin or orthopedic surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Sensory-Enhanced Home-based Intensive Program (SE-HIP)Videos include sensory preparation and intensive motor practice delivered asynchronously at home. | Other | Sensory-Enhanced Home-based Intensive Program (SE-HIP) |
| Standard Home Program (SHP)Videos cover standard home exercise activities delivered asynchronously at home. | Other | Standard Home Program (SHP) |
Primary outcome
Nine-Hole Peg Test
Time frame: Baseline and after 6 weeks of training
Assesses fine manual dexterity (finger dexterity). The patient places and removes nine pegs into a board as quickly as possible.
Box and Block Test
Time frame: Baseline and after 6 weeks of training
Assesses gross manual dexterity. The patient moves small wooden blocks across a partition in 60 seconds
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Apr 2026.
- Background: PubMed 38428904Kashif M, Albalwi A, Mehdi Kazmi SA, Alharbi AA, Bashir K, Aqeel Aslam M, Ghaffar T. Role of telerehabilitation in the rehabilitation of children with cerebral palsy during COVID-19: A review. Medicine (Baltimore). 2024 Mar 1;103(9):e37214. doi: 10.1097/MD.0000000000037214.
- Background: PubMed 32805150Molinaro A, Micheletti S, Pagani F, Garofalo G, Galli J, Rossi A, Fazzi E, Buccino G. Action Observation Treatment in a tele-rehabilitation setting: a pilot study in children with cerebral palsy. Disabil Rehabil. 2022 Apr;44(7):1107-1112. doi: 10.1080/09638288.2020.1793009. Epub 2020 Aug 17.
- Individual participant dataSharing planned: No. There is currently no plan to share de-identified individual participant data (IPD) from this trial outside the primary research group.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Sensory-Enhanced Home-based Intensive Program (SE-HIP) and Standard Home Program (SHP) in people with Cerebral Palsy (CP) and Tele-rehabilitation, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Nine-Hole Peg Test (time frame: Baseline and after 6 weeks of training). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07518511, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Apr 2026.