Diabetic Retinopathy (DR)NCT07519707
Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center
A study testing Animated Videos in people with Diabetic Retinopathy (DR) and Macular Edema (ME), run by University of California, San Francisco at 1 site in United States.
Trial summary
The study will evaluate whether videos can improve understanding of diabetic eye disease, and follow-up rates in the eye clinic. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Diabetic Retinopathy (DR), Macular Edema (ME)
- What is being tested?
- Animated Videos
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 150 participants
- Where
- 1 siteUnited States
- Study dates
- Sep 2026to Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosis of diabetes mellitus with or without diabetic retinopathy
- Scheduled visit to ZSFG clinic is specifically for diabetes mellitus or diabetic retinopathy care
- Able to speak and understand English or Spanish
Who cannot join
- Unable to view or understand the videos due to significant vision obstruction or impairment
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Zuckerberg San Francisco General Hospital and Trauma Center
San Francisco, California, 94110
Sriranjani Padmanabhan, MD, 415-353-2020, eyestudy@ucsf.edu
About this study
Official title: Addressing Low Patient Follow-up Rates Among Patients With Diabetes in the Eye Clinic at Zuckerberg San Francisco General Hospital and Trauma Center
The study will evaluate whether videos can improve understanding of diabetic eye disease, and follow-up rates in the eye clinic.
Read the detailed description
Health literacy is a prevalent issue at Zuckerberg San Francisco General Hospital, particularly at the eye clinic where understanding of diagnoses and treatment plans largely affect vision outcomes. This study will determine whether video-based explanations, created in both English and Spanish, of diabetic retinopathy can improve knowledge concordance and follow up rates among patients in the eye clinic. Knowledge concordance and patient satisfaction will be assessed through digital surveys in Qualtrics.
- Conditions
- Diabetic Retinopathy (DR), Macular Edema (ME)
- Being tested
- Animated Videos
- Keywords
- diabetic retinopathy, diabetes, ophthalmology, vision, health literacy
- Medical subject headings
- Diabetic Retinopathy, Macular Edema, Diabetes Mellitus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Animated VideosBehavioural
Animated videos (in English and Spanish) that describe diabetic retinopathy.
| Study group | Role | What they receive |
|---|---|---|
| Experimental Group | Experimental | Videos Receives: Behavioral: Animated Videos |
| Control | No intervention | Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Knowledge Concordance Assessed through Validated Questionarres
Validated questionnaires in Qualtrics consisting of multiple choice questions and scales from 0 through 10 will be used to assess knowledge concordance before and after the patient's appointment. The change in concordance will be determined for each patient.
Measured: 12 months
Secondary outcomes (2)
Follow Up Adherence, Assessed through Electronic Record Review
The number of scheduled follow-up appointments versus the number of attended follow-up appointments will be compared for each patient through electronic record review.
Measured: 12 months
Diabetic Retinopathy Progression, Assessed through Electronic Health Record Review
Electronic health records and ocular imaging will be reviewed to determine whether patients' diabetic retinopathy has progressed or improved. The numbers of patients with mild, moderate, severe, and proliferative diabetic retinopathy will be compared between groups at the end of the study period.
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Apr 2026
- Study startSep 2026 (estimated)
- Primary completionDec 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Diabetic Retinopathy (DR)Studies of the same condition, open and under way.
- More trials run by University of California, San FranciscoThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 150 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of California, San Francisco
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Sriranjani Padmanabhan, MD, Principal investigator, University of California, San Francisco
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07519707
- Sponsor's protocol ID
- 24-43161
- Status last verified
- Jul 2026
- First submitted
- 20 Mar 2026
- Last updated
- 22 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Addressing Low Patient Follow-up Rates Among Patients With Diabetes in the Eye Clinic at Zuckerberg San Francisco General Hospital and Trauma Center
- ClinicalTrials.gov ID
- NCT07519707
- Acronym / sponsor ID
- 24-43161
- Conditions
- Diabetic Retinopathy (DR), Macular Edema (ME)
- Keywords
- diabetic retinopathy, diabetes, ophthalmology, vision, health literacy
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 150 participants (estimated)
- Lead sponsor
- University of California, San FranciscoUniversity, hospital or other
- Study start
- Sep 2026 (estimated)
- Primary completion
- Dec 2027 (estimated)
- Study completion
- Dec 2027 (estimated)
- First posted
- 9 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study will evaluate whether videos can improve understanding of diabetic eye disease, and follow-up rates in the eye clinic.
Detailed description
Health literacy is a prevalent issue at Zuckerberg San Francisco General Hospital, particularly at the eye clinic where understanding of diagnoses and treatment plans largely affect vision outcomes. This study will determine whether video-based explanations, created in both English and Spanish, of diabetic retinopathy can improve knowledge concordance and follow up rates among patients in the eye clinic. Knowledge concordance and patient satisfaction will be assessed through digital surveys in Qualtrics.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimental Group | Experimental | Behavioral: Animated VideosVideos |
| Control | No intervention | –Control |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Diagnosis of diabetes mellitus with or without diabetic retinopathy
- Scheduled visit to ZSFG clinic is specifically for diabetes mellitus or diabetic retinopathy care
- Able to speak and understand English or Spanish
Key exclusion criteria (1 listed)
- Unable to view or understand the videos due to significant vision obstruction or impairment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Animated VideosAnimated videos (in English and Spanish) that describe diabetic retinopathy. | Behavioural | Experimental Group |
Primary outcome
Change in Knowledge Concordance Assessed through Validated Questionarres
Time frame: 12 months
Validated questionnaires in Qualtrics consisting of multiple choice questions and scales from 0 through 10 will be used to assess knowledge concordance before and after the patient's appointment. The change in concordance will be determined for each patient.
2 secondary outcomes
Follow Up Adherence, Assessed through Electronic Record Review
Time frame: 12 months
Diabetic Retinopathy Progression, Assessed through Electronic Health Record Review
Time frame: 12 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sriranjani Padmanabhan, MD principal investigator
University of California, San Francisco
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Animated Videos in people with Diabetic Retinopathy (DR) and Macular Edema (ME), run by University of California, San Francisco at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 22 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sriranjani Padmanabhan, MD (415-353-2020, eyestudy@ucsf.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Knowledge Concordance Assessed through Validated Questionarres (time frame: 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jul 2026.