Socket Shield TechniqueCGFNCT07520526
Immediate Implant Placement Using Socket Shield With CGF
A study testing Immediate implant placement with Socket Shield Technique and CGF in people with Socket Shield Technique and Concentrated Growth Factors, run by Cairo University at 1 site in Egypt.
Trial summary
This prospective case series study aims to clinically and radiographically evaluate the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) in immediate implant placement in the esthetic zone. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Socket Shield Technique, Concentrated Growth Factors, Immediate Dental Implant Placement
- What is being tested?
- Immediate implant placement with Socket Shield Technique and CGF
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 7 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Apr 2026to 30 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age ≥18 years old. (Younis, W., \& El-Rashidy, A. 2020).
- Both male and female patients.
- Maxillary, anterior and premolar segment.
Who cannot join
- A medical history that contraindicates oral surgical treatment such as (uncontrolled/untreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and/or intravenous bisphosphonates).
- Presence of active or untreated periodontal disease.
- Vertical root fractures involving the buccal aspect.
- Tooth /teeth with horizontal fractures below bone level.
- Tooth /teeth with external or internal resorption.
- Patients with destructive oral habits such as smoking, chewing tobacco, bruxism, etcetera.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Areej Khalid Rasheid, bachelors contact
About this study
Official title: Clinical and Radiographic Evaluation of Concentrated Growth Factors With Simultaneous Immediate Implant Placement in Socket Shield Technique
This prospective case series study aims to clinically and radiographically evaluate the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) in immediate implant placement in the esthetic zone. Outcomes will include crestal bone level changes assessed by CBCT and implant stability measured using Osstell.
Read the detailed description
This prospective case series study will be conducted to evaluate clinically and radiographically the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) during immediate implant placement in the esthetic zone.
Eligible patients requiring extraction and immediate implant placement in the maxillary anterior or premolar region will be included. Following atraumatic extraction, partial extraction therapy using the socket shield technique will be performed, leaving the buccal root fragment in place. Implant osteotomy and placement will then be carried out according to manufacturer instructions.
Autologous concentrated growth factors will be prepared from the patient's blood using a CGF centrifugation protocol. The CGF gel will be packed into the jumping gap between the implant and socket wall to promote bone regeneration and healing.
Clinical and radiographic evaluation will be performed using CBCT at baseline, 2 weeks, and 6 months postoperatively. The primary outcome will be crestal bone level changes measured radiographically, while the secondary outcome will include implant stability assessed using Osstell measurements (ISQ values).
Seven participants will be recruited in this case series. Follow-up will be conducted to evaluate healing, bone remodeling, and implant stability.
- Conditions
- Socket Shield Technique, Concentrated Growth Factors, Immediate Dental Implant Placement, Alveolar Bone Preservation, Alveolar Bone Loss
- Being tested
- Immediate implant placement with Socket Shield Technique and CGF
- Keywords
- Socket shield technique, immediate implants, concentrated growth factor
- Medical subject headings
- Alveolar Bone Loss
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Immediate implant placement with Socket Shield Technique and CGFProcedure or surgery
Also called Socket Shield technique, Concentrated Growth Factors, Immediate implant placement
Partial extraction therapy using the socket shield technique followed by immediate implant placement. Concentrated growth factors prepared from autologous blood will be packed in the jumping gap to enhance bone regeneration and healing.
| Study group | Role | What they receive |
|---|---|---|
| Socket Shield Technique with CGF | Experimental | Immediate implant placement using socket shield technique combined with concentrated growth factors in the esthetic zone. Receives: Procedure: Immediate implant placement with Socket Shield Technique and CGF |
What is being measured
The primary outcome is the main question the study is designed to answer.
Crestal bone level
Radiographic evaluation of crestal bone level changes around the implant using CBCT, measured in millimeters (mm).
Measured: 2 weeks and 6 months post-operatively
Secondary outcomes (1)
Implant stability
Implant stability will be assessed using resonance frequency analysis with the Osstell device and recorded as Implant Stability Quotient (ISQ). ISQ values range from 1 to 100, where higher values indicate greater implant stability and a better outcome.
Measured: Immediately after implant placement and at 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Apr 2026
- Study start1 Apr 2026 (estimated)
- Primary completion1 Sep 2026 (estimated)
- Study completion30 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Socket Shield TechniqueStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 7 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Areej khalid rashyd, Cairo University
- Investigators
- Tarek I.A El-Ghareeb, PHD Holder, Study chair, Cairo UniversityAbdelmoez Mohamed El-Sharkawy, Associate professor, Study director, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07520526
- Sponsor's protocol ID
- omfs_ 3-3-20
- Acronym
- CGF
- Status last verified
- Apr 2026
- First submitted
- 3 Apr 2026
- Last updated
- 13 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical and Radiographic Evaluation of Concentrated Growth Factors With Simultaneous Immediate Implant Placement in Socket Shield Technique
- ClinicalTrials.gov ID
- NCT07520526
- Acronym / sponsor ID
- CGF / omfs_ 3-3-20
- Conditions
- Socket Shield Technique, Concentrated Growth Factors, Immediate Dental Implant Placement, Alveolar Bone Preservation, Alveolar Bone Loss
- Keywords
- Socket shield technique, immediate implants, concentrated growth factor
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 7 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Apr 2026 (estimated)
- Primary completion
- 1 Sep 2026 (estimated)
- Study completion
- 30 Dec 2026 (estimated)
- First posted
- 9 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective case series study aims to clinically and radiographically evaluate the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) in immediate implant placement in the esthetic zone. Outcomes will include crestal bone level changes assessed by CBCT and implant stability measured using Osstell.
Detailed description
This prospective case series study will be conducted to evaluate clinically and radiographically the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) during immediate implant placement in the esthetic zone.
Eligible patients requiring extraction and immediate implant placement in the maxillary anterior or premolar region will be included. Following atraumatic extraction, partial extraction therapy using the socket shield technique will be performed, leaving the buccal root fragment in place. Implant osteotomy and placement will then be carried out according to manufacturer instructions.
Autologous concentrated growth factors will be prepared from the patient's blood using a CGF centrifugation protocol. The CGF gel will be packed into the jumping gap between the implant and socket wall to promote bone regeneration and healing.
Clinical and radiographic evaluation will be performed using CBCT at baseline, 2 weeks, and 6 months postoperatively. The primary outcome will be crestal bone level changes measured radiographically, while the secondary outcome will include implant stability assessed using Osstell measurements (ISQ values).
Seven participants will be recruited in this case series. Follow-up will be conducted to evaluate healing, bone remodeling, and implant stability.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Socket Shield Technique with CGF | Experimental | Procedure: Immediate implant placement with Socket Shield Technique and CGFImmediate implant placement using socket shield technique combined with concentrated growth factors in the esthetic zone. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Age ≥18 years old. (Younis, W., \& El-Rashidy, A. 2020).
- Both male and female patients.
- Maxillary, anterior and premolar segment.
Key exclusion criteria (6 listed)
- A medical history that contraindicates oral surgical treatment such as (uncontrolled/untreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and/or intravenous bisphosphonates).
- Presence of active or untreated periodontal disease.
- Vertical root fractures involving the buccal aspect.
- Tooth /teeth with horizontal fractures below bone level.
- Tooth /teeth with external or internal resorption.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Immediate implant placement with Socket Shield Technique and CGFAlso: Socket Shield technique, Concentrated Growth Factors, Immediate implant placementPartial extraction therapy using the socket shield technique followed by immediate implant placement. Concentrated growth factors prepared from autologous blood will be packed in the jumping gap to enhance bone regeneration and healing. | Procedure or surgery | Socket Shield Technique with CGF |
Primary outcome
Crestal bone level
Time frame: 2 weeks and 6 months post-operatively
Radiographic evaluation of crestal bone level changes around the implant using CBCT, measured in millimeters (mm).
1 secondary outcome
Implant stability
Time frame: Immediately after implant placement and at 6 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Apr 2026.
- Individual participant dataSharing planned: No
Related trials for Socket Shield Technique
Recruiting
Guided Root Slice Replantation vs. Socket Shielding for Immediate Implant Placement in Esthetic Zone
TEETH EXTRACTION, Esthetic Zone Implantology
Not yet recruiting
Multicenter Clinical Study on the Efficacy and Esthetic Outcomes of Immediate Implant Placement Using the Socket-Shield Technique Versus Conventional Immediate Implantation in the Anterior Maxillary Esthetic Zone
Teeth Absent, Teeth Missing
Active, not recruiting
Effect of Subepithelial Connective Tissue Graft With Socket Shield Technique
Socket Shield Technique Implant Placement, Immediate Implant Placement
Recruiting
Comparison Between Socket Shield and Conventional Techniques in Immediate Implant Placement.
Bone Density, Bone Level
Not yet recruiting
Supracrestal Socket Shield Technique in Anterior Maxilla. A Case Series
Immediate Dental Implant Placement, Anterior Maxilla
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Areej Khalid Rasheid, bachelors contact
Tarek I.A El-Ghareeb, PHD Holder study chair
Cairo University
Abdelmoez Mohamed El-Sharkawy, Associate professor study director
Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Immediate implant placement with Socket Shield Technique and CGF in people with Socket Shield Technique and Concentrated Growth Factors, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 13 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Areej Khalid Rasheid, bachelors (+201033903216 ext. +201033903216, areej.rashyd@dentistry.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Crestal bone level (time frame: 2 weeks and 6 months post-operatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Apr 2026.