Colorectal Cancer ScreeningNCT07522177
Animated Storytelling to Promote Colorectal Cancer Screening
A study testing Short animated storytelling video in people with Colorectal Cancer Screening, run by Stanford University at 1 site in United States.
Trial summary
This online randomized controlled trial will evaluate whether a short animated storytelling video increases behavioral expectation to obtain colorectal cancer screening among screening-eligible U.S. adults who report not yet having completed screening. Read more about this study
- Who is it for?
- Ages 45 years and older
- Conditions the study is for
- Colorectal Cancer Screening
- What is being tested?
- Short animated storytelling video
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 3,000 participants
- Where
- 1 siteUnited States
- Study dates
- 16 Oct 2026to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Resides in the United States
- Able to read and understand English
- Self-reports not having completed colorectal cancer screening
- Provides electronic informed consent
Who cannot join
- Prior diagnosis of colorectal cancer
- Self-reported completion of colorectal cancer screening
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Stanford University
Stanford, California, 94305
Maya Adam, MD, PhD, 650-839-3600, madam@stanford.edu
About this study
Official title: Using Short Animated Storytelling to Increase Intent for Colorectal Cancer Screening: A U.S. Online Randomized Controlled Trial
This online randomized controlled trial will evaluate whether a short animated storytelling video increases behavioral expectation to obtain colorectal cancer screening among screening-eligible U.S. adults who report not yet having completed screening. Participants will be recruited via Prolific and randomized in Stanford Qualtrics to view either a brief animated video or a time-neutral informational text. Outcomes will be assessed immediately after exposure.
- Conditions
- Colorectal Cancer Screening
- Being tested
- Short animated storytelling video
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Short animated storytelling videoBehavioural
A brief animated storytelling video about colorectal cancer screening and colonoscopy.
| Study group | Role | What they receive |
|---|---|---|
| Animated Storytelling Video | Experimental | Participants view a brief animated storytelling video about colorectal cancer screening and colonoscopy. Receives: Behavioral: Short animated storytelling video |
| Do-nothing Control | No intervention | Participants complete surveys only and receive no intervention. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change from baseline in behavioral expectation (simple and next-step) to obtain colorectal cancer screening, as measured by a 7-item visual analogue scale.
Participant self-reports their likelihood of discussing, scheduling, or obtaining colorectal cancer screening after exposure to assigned study material. Total scores range from 0-70 with higher scores indicating greater behavioral expectation (Item 7 is reverse scored).
Measured: Baseline, immediately post-intervention exposure (up to 24 hours)
Secondary outcomes (2)
Change from baseline in knowledge about colorectal cancer screening and colonoscopy, as measured by a 5-item knowledge questionnaire.
Self-reported knowledge regarding colorectal cancer screening and the preventive role of colonoscopy, including detection and removal of pre-cancerous polyps. Response options are true/false/not sure, with 1 point per correct answer and 0 points for incorrect or "not sure". Total scores range from 0-5, with higher scores indicating higher knowledge.
Measured: Baseline, immediately post-intervention exposure (up to 24 hours)
Change from baseline in perceptions and beliefs about colonoscopy, as measured by a 13-item scale.
Self-reported perceptions an beliefs about colonoscopy include perceived susceptibility, perceived severity, perceived benefits and perceived barriers. Responses will be compared on a Likert scale that ranges from 1-5 (Strongly disagree / Disagree / Neither / Agree / Strongly agree), where higher scores indicate more positive perceptions and beliefs, with the perceived barriers section reverse scored.
Measured: Baseline, immediately post-intervention exposure (up to 24 hours)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Apr 2026
- Study start16 Oct 2026
- Primary completionNov 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Colorectal Cancer ScreeningStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 3,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Collaborators
- Heidelberg University
- Responsible party
- Principal investigator, Maya Adam, Stanford University
- Investigators
- Maya Adam, MD, PhD, Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07522177
- Sponsor's protocol ID
- 85776
- Status last verified
- Oct 2026
- First submitted
- 3 Apr 2026
- Last updated
- 29 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Using Short Animated Storytelling to Increase Intent for Colorectal Cancer Screening: A U.S. Online Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07522177
- Acronym / sponsor ID
- 85776
- Conditions
- Colorectal Cancer Screening
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 3,000 participants (estimated)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Collaborators
- Heidelberg University
- Study start
- 16 Oct 2026 (actual)
- Primary completion
- Nov 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 13 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This online randomized controlled trial will evaluate whether a short animated storytelling video increases behavioral expectation to obtain colorectal cancer screening among screening-eligible U.S. adults who report not yet having completed screening. Participants will be recruited via Prolific and randomized in Stanford Qualtrics to view either a brief animated video or a time-neutral informational text. Outcomes will be assessed immediately after exposure.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Animated Storytelling Video | Experimental | Behavioral: Short animated storytelling videoParticipants view a brief animated storytelling video about colorectal cancer screening and colonoscopy. |
| Do-nothing Control | No intervention | –Participants complete surveys only and receive no intervention. |
Who may qualify
- Ages
- 45 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Resides in the United States
- Able to read and understand English
- Self-reports not having completed colorectal cancer screening
- Provides electronic informed consent
Key exclusion criteria (2 listed)
- Prior diagnosis of colorectal cancer
- Self-reported completion of colorectal cancer screening
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Short animated storytelling videoA brief animated storytelling video about colorectal cancer screening and colonoscopy. | Behavioural | Animated Storytelling Video |
Primary outcome
Change from baseline in behavioral expectation (simple and next-step) to obtain colorectal cancer screening, as measured by a 7-item visual analogue scale.
Time frame: Baseline, immediately post-intervention exposure (up to 24 hours)
Participant self-reports their likelihood of discussing, scheduling, or obtaining colorectal cancer screening after exposure to assigned study material. Total scores range from 0-70 with higher scores indicating greater behavioral expectation (Item 7 is reverse scored).
2 secondary outcomes
Change from baseline in knowledge about colorectal cancer screening and colonoscopy, as measured by a 5-item knowledge questionnaire.
Time frame: Baseline, immediately post-intervention exposure (up to 24 hours)
Change from baseline in perceptions and beliefs about colonoscopy, as measured by a 13-item scale.
Time frame: Baseline, immediately post-intervention exposure (up to 24 hours)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Oct 2026.
- Individual participant dataSharing planned: No
Related trials for Colorectal Cancer Screening
Recruiting
The Vanguard Study: Testing a New Way to Screen for Cancer
Bladder Carcinoma, Breast Carcinoma
Not yet recruiting
Improving Colorectal Cancer Screening Uptake Through Education and Stool-Based Testing Outreach
Colorectal Cancer (CRC) Screening, CRC Screening
Active, not recruitingObservational study
Prostate Lung Colorectal and Ovarian (PLCO) Cancer Screening Trial
Cancer, Death
RecruitingObservational study
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
RecruitingObservational study
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Brain Cancer, Breast Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Maya Adam, MD, PhD principal investigator
Stanford University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Short animated storytelling video in people with Colorectal Cancer Screening, run by Stanford University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 29 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change from baseline in behavioral expectation (simple and next-step) to obtain colorectal cancer screening, as measured by a 7-item visual analogue scale. (time frame: Baseline, immediately post-intervention exposure (up to 24 hours)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Oct 2026.