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Mood DisordersNCT07523490

Investigation on Suicide Risk Factors of Patients With Mood Disorders

An observational study of Mood Disorders and Suicide, run by Tianjin Anding Hospital at 1 site in China.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

This study investigates the level and distribution of suicide risk and learned suicide ability of patients with mood disorders, investigates the related risk factors of suicide and suicide ability formation of patients with mood disorders from multiple dimensions (biological, psychological, social and clinical… Read more about this study

Who is it for?
Ages 16 to 60 years
Conditions the study is for
Mood Disorders, Suicide
How many people
300 participants
Where
1 siteChina
Study dates
31 Dec 2025to 30 Sep 2027
How long will I take part?
3 Months
Phase
Observational
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 16 to 60 years
  • All sexes
  • No healthy volunteers
  • Child, Adult

Study population: This study will recruit 300 patients meeting the diagnostic criteria of ICD-11 mood disorder.The 300 subjects, aged16 to 60 years old, come from Tianjin Anding Hospital's inpatient/outpatient services and must consent to participate. Exclusion Criteria are as follows:(1) unable to understand the contents of the questionnaire;(2) Serious organic diseases such as cardiovascular disease, brain disease, liver disease and kidney disease, and weak body, which affect the respondents of the questionnaire;(3) Other circumstances that make it impossible or unwilling to cooperate with the completion of the questionnaire.

Who may be able to join

  • Age: 16 to 60 years old;
  • seeing a doctor in a psychiatric clinic or a general hospital;
  • Willing to cooperate in this research project;
  • Sign the informed consent form (minors also need to obtain the informed consent signature of the guardian);
  • Meet the diagnostic criteria of ICD-11 mood disorder.

Who cannot join

  • unable to understand the contents of the questionnaire;
  • Serious organic diseases such as cardiovascular disease, brain disease, liver disease and kidney disease, and weak body, which affect the respondents of the questionnaire;
  • Other circumstances that make it impossible or unwilling to cooperate with the completion of the questionnaire.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

China1 site, 1 recruiting
  • Tianjin Anding Hospital

    Tianjin, Tianjin Municipality, 300000

    Jie Li, jieli@tjmhc.com

    Recruiting

Other trials in China

About this study

Official title: Investigation on Suicide Risk Factors of Patients With Mood Disorders in China

This study investigates the level and distribution of suicide risk and learned suicide ability of patients with mood disorders, investigates the related risk factors of suicide and suicide ability formation of patients with mood disorders from multiple dimensions (biological, psychological, social and clinical perspectives) and clarifies their importance, forms a list of suicide risk factors, and establishes a prediction model of learned suicide ability formation. Upon enrollment, participants will undergo comprehensive assessments including blood and urine sample collection and scale evaluation. The collection of scientific blood and urine is mainly used for the exploration of molecular mechanism of disease occurrence and development, the discovery and verification of biomarkers. Scale evaluation includes: Beck Scale for Suicide Ideation , Columbia Suicide Severity Rating Scale,, Hamilton Depression Rating Scale , Hamilton Anxiety Rating Scale, PHQ-9, GAD-7, Personal and Social Function Scale , Schihan Disability Scale , Emotional Adjustment Difficulty Scale , Acquired Capability for Suicide Scale, Interpersonal Needs Questionnaire , Ottawa Self-Injury Scale, Chinese version of Stress Perception Scale and Beck Hopelessness Scale . Follow-up was carried out for 3 months, including whether suicide/self-injury occurred, current status, and some baseline questionnaires (such as BSI-CV, GAD-7, PHQ-9, HAMD-17,HAMA, etc.).

Keywords
Mood Disorders, suicide, Biological Mechanism, prediction model
Medical subject headings
Mood Disorders, Suicide

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT07523490
Study groupRoleWhat they receive
patients with mood disorders1. Age: 16 to 60 years old; 2. seeing a doctor in a psychiatric clinic or a general hospital; 3. Willing to cooperate in this research project; 4. Sign the informed consent form (minors also need to obtain the informed consent signature of the guardian); 5. Meet the diagnostic criteria of ICD-11 mood disorder.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Columbia Suicide Severity Rating Scale

    Columbia Suicide Severity Rating Scale (C-SSRS) is a tool for evaluating the risk of individual suicide. It includes a series of questions to evaluate the frequency, intensity, persistence and concreteness of individual suicide behavior in the past period of time. The purpose of C-SSRS scale is to distinguish between suicidal ideation and suicidal attempt and higher scores mean a worse outcome. Developed by researchers from Columbia University, the scale is widely used in clinical and research fields to help identify and manage suicide risks.

    Measured: baseline, 3 months

Secondary outcomes (8)
  1. Beck Scale for Suicide Ideation

    Beck Scale for Suicide Ideation (BSI-CV) assesses the individual's thoughts about life and death and the severity of suicidal thoughts through series of questions. There are 19 items in the scale, which are divided into two dimensions: suicidal ideation and suicidal tendency. Each question is asked for two time periods, that is, the last week and the most depressed, melancholy or suicidal time in the past (that is, the most serious time). The scale adopts a three-level scoring system, that is, 0~2 points, and the total score is between 0~38 points. The higher the score, the stronger the suicidal ideation and the higher the risk of suicide.

    Measured: baseline, 3 months

  2. Hamilton Depression Rating Scale

    Hamilton Depression Rating Scale (HAMD-17), also known as Hamilton Depression Rating Scale, is a clinical tool for evaluating the severity of depressive symptoms, mainly evaluating patients' depressive symptoms in the past week, including mood, sleep, cognitive function, behavior and physical symptoms. According to the specific performance of patients, doctors or clinical evaluators will give corresponding scores. The total score ranges from 0 to 52 points. The higher the total score, the more serious the depressive symptoms are.

    Measured: baseline, 3 months

  3. Hamilton Anxiety Rating Scale

    Hamilton Anxiety Rating Scale (HAMA) is a clinical tool for evaluating the severity of anxiety symptoms. The scale was compiled by psychologist Hamilton in 1959, and it is widely used in clinical diagnosis, treatment effect evaluation and research work in psychiatry. HAMA contains 14 items, covering psychological anxiety and physical anxiety. Each item is scored according to the severity of symptoms, and the higher the total score, the more serious the anxiety symptoms are. The total score ranges from 0 to 56 points. Scoring standards are usually divided into four grades: mild, moderate, severe and extremely severe.

    Measured: baseline, 3 months

  4. Patient Health Questionnare

    Patient Health Question Nare (PHQ-9): It contains 9 questions, mainly focusing on depressed mood, lack of pleasure, sleep disorder, decreased energy, change of appetite, difficulty in concentration, reduced sense of self-worth, negative ideas or suicidal thoughts. Scores range from 0 to 27, with higher scores indicating more severe depressive symptoms.

    Measured: baseline, 3 months

  5. Generalized Anxiety Disorder

    Generalized Anxiety Disorder-7 (GAD-7): Self-rating anxiety scale, a total of 7 items, respectively: 1 nervous anxiety, 2 uncontrollable worries, 3 excessive worries, 4 inability to relax, 5 akathisia, 6 irritability, 7 sense of foreboding. Scores range from 0 to 21, with higher scores indicating more severe anxiety symptoms.

    Measured: baseline, 3 months

  6. acquired capability for suicide scale

    acquired capability for suicide scale (ACSS): The scale includes two sub-scales: reduced fear of death and improved physical pain tolerance, with a total of 20 topics. Each topic is scored on a 5-point Lickert scale of 1 (completely inconsistent) to 5 (completely consistent), of which 7 topics are reverse scoring. The higher the score, the lower the individual's fear of death and the higher the physical pain tolerance.

    Measured: baseline, 3 months

  7. Interpersonal Needs Questionnaire

    The Interpersonal Needs Questionnaire (INQ) consists of two subscales: thwarted belongingness (9 items) and perceived burdensomeness (6 items). Each item is scored on a 7-point Likert scale ranging from 1 (not at all true for me) to 7 (very true for me), with 6 items reverse-scored. Scores range from 9 to 63 for thwarted belongingness and from 6 to 42 for perceived burdensomeness. Higher scores indicate greater levels of thwarted belongingness and perceived burdensomeness, reflecting more severe interpersonal distress and unmet interpersonal needs.

    Measured: baseline, 3 months

  8. Beck Hopelessness Scale

    Beck Hopelessness Scale (BHS): Used to measure the degree of hopelessness that individuals feel. Hopelessness refers to the psychological state in which individuals are pessimistic about the future and believe that their efforts will not bring positive results. This feeling may be associated with depression, anxiety, and other mental health problems. The scale consists of 20 items, with scores ranging from 0 to 20, where higher scores indicate greater levels of hopelessness.

    Measured: baseline, 3 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted13 Apr 2026
  2. Study start31 Dec 2025
  3. Primary completion30 Sep 2027 (estimated)
  4. Study completion30 Sep 2027 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
300 participants (estimated)
Target duration
3 Months
IDs, dates and publications
ClinicalTrials.gov ID
NCT07523490
Sponsor's protocol ID
MD-SU
Status last verified
Apr 2026
First submitted
5 Apr 2026
Last updated
22 Apr 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No

Questions about this trial

What is this clinical trial studying?

An observational study of Mood Disorders and Suicide, run by Tianjin Anding Hospital at 1 site in China.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 22 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Xue Tian (+86-13602182093, 576491743@qq.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Columbia Suicide Severity Rating Scale (time frame: baseline, 3 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Apr 2026.

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