Colorectal CancerNCT07526090
Identification of Regional Epidemiological Characteristics and Key Prognostic Factors of Colorectal Cancer in Xinjiang and Shandong
An observational study of Colorectal Cancer, run by Qianfoshan Hospital at 1 site in China.
Trial summary
This is a multicenter, retrospective, cross-sectional observational study aiming to investigate the 5-year overall survival (OS) rate of colorectal cancer (CRC) patients in Xinjiang and Shandong provinces of China. Read more about this study
- Who is it for?
- Ages 18 to 120 years
- Conditions the study is for
- Colorectal Cancer
- What is being tested?
- Retrospective Data Collection
- How many people
- 500 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2016to 31 Dec 2020
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 120 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: This is a retrospective, cross-sectional, multicenter observational study. The study population includes patients pathologically diagnosed with colorectal adenocarcinoma between January 1, 2016 and December 31, 2020 from medical centers in Xinjiang Uygur Autonomous Region and Shandong Province. Patients aged 18 years and above with complete clinical, pathological, treatment and follow-up data will be included. The study aims to analyze the regional epidemiological characteristics and prognostic factors of colorectal cancer.
Who may be able to join
- 1. Pathologically confirmed colorectal adenocarcinoma.
- 2. Patients diagnosed between January 1, 2016 and December 31, 2020.
- 3. Age ≥ 18 years old.
- 4. Complete clinical, pathological, treatment and follow-up data available.
- 5. Patients from medical centers in Xinjiang and Shandong regions.
Who cannot join
- 1. Other pathological types of malignant tumors except colorectal adenocarcinoma.
- 2. Patients with incomplete clinical data or lost to follow-up.
- 3. Patients with severe organ dysfunction or other malignant tumors that may affect survival.
- 4. Age < 18 years old.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Identification of Regional Epidemiological Characteristics and Key Prognostic Factors of Colorectal Cancer in Xinjiang and Shandong: A Multicenter, Retrospective Study
This is a multicenter, retrospective, cross-sectional observational study aiming to investigate the 5-year overall survival (OS) rate of colorectal cancer (CRC) patients in Xinjiang and Shandong provinces of China. A total of no less than 500 pathologically confirmed CRC patients from 7 medical centers during January 1, 2016 to December 31, 2020 will be enrolled. We will collect and analyze the demographic characteristics, lifestyle, clinical pathological features, treatment patterns and survival prognosis data of patients, explore the regional differences of CRC and its key prognostic factors, and construct a CRC prognostic prediction model. The results will provide theoretical guidance for clinical practice and the formulation of public health policies.
Read the detailed description
Colorectal cancer is one of the most common malignant tumors with obvious regional distribution differences in incidence and prognosis. There are significant differences in economic development, lifestyle, dietary structure and medical resource allocation between Xinjiang (western China) and Shandong (eastern China), which may lead to different epidemiological characteristics and prognosis of CRC patients in the two regions. This study will enroll CRC patients from 7 multicenters in Xinjiang and Shandong, collect retrospective clinical data including demographic information, pathological features, treatment modes and follow-up records, use statistical methods such as Kaplan-Meier survival analysis and Cox proportional hazard regression model to analyze the 5-year OS rate and prognostic factors of patients in the two regions, compare the regional differences of CRC, and construct a Nomogram prognostic prediction model. The study will provide a scientific basis for the personalized treatment and regional public health prevention and control of CRC.
- Conditions
- Colorectal Cancer
- Being tested
- Retrospective Data Collection
- Keywords
- Colorectal Cancer, Epidemiology, Prognostic Factors, Survival, Retrospective, Multicenter, Xinjiang, Shandong
- Medical subject headings
- Colorectal Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Retrospective Data CollectionOther
Also called Retrospective Clinical Data Collection and Analysis for Colorectal Cancer
Retrospective collection, collation and statistical analysis of de-identified clinical, pathological, treatment and follow-up data of pathologically confirmed colorectal cancer patients from 7 medical centers in Xinjiang and Shandong provinces from January 1, 2016 to December 31, 2020. The collected data includes demographic characteristics, lifestyle, tumor clinical pathological features, treatment patterns and 5-year overall survival status, for the purpose of analyzing regional epidemiological characteristics and key prognostic factors of colorectal cancer.
| Study group | Role | What they receive |
|---|---|---|
| Group/Cohort Label 1：Xinjiang CRC Cohort | Retrospective collection and analysis of clinical, pathological and follow-up data of pathologically confirmed colorectal cancer patients from medical centers in Xinjiang region, including demographic characteristics, lifestyle, treatment patterns and 5-year overall survival status. Receives: Other: Retrospective Data Collection | |
| Group/Cohort Label 2：Shandong CRC Cohort | Retrospective collection and analysis of clinical, pathological and follow-up data of pathologically confirmed colorectal cancer patients from medical centers in Shandong region, including demographic characteristics, lifestyle, treatment patterns and 5-year overall survival status. Receives: Other: Retrospective Data Collection |
What is being measured
The primary outcome is the main question the study is designed to answer.
5-year Overall Survival
Five-year overall survival rate of patients with colorectal cancer, defined as the time from pathological diagnosis to death from any cause or last follow-up.
Measured: 5 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Apr 2026
- Study start1 Jan 2016
- Primary completion31 Dec 2020
- Study completion31 Dec 2020
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Colorectal CancerStudies of the same condition, open and under way.
- More trials run by Qianfoshan HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case crossover
- Time perspective
- Retrospective
- Enrolment
- 500 participants (actual)
Sponsor and investigators
- Lead sponsor
- Qianfoshan Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- The Second Affiliated Hospital of Shandong First Medical University, Affiliated Hospital of Jining Medical University, Xinjiang Medical University
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07526090
- Sponsor's protocol ID
- YXLL-KY-2026(047）
- Status last verified
- Feb 2026
- First submitted
- 6 Apr 2026
- Last updated
- 13 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is no plan to share individual participant data (IPD) from this study. Data will be used only for the purpose of this retrospective observational study and will not be shared with third parties.
Study at a glance
From the registry record, last updated by the sponsor on 13 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Identification of Regional Epidemiological Characteristics and Key Prognostic Factors of Colorectal Cancer in Xinjiang and Shandong: A Multicenter, Retrospective Study
- ClinicalTrials.gov ID
- NCT07526090
- Acronym / sponsor ID
- YXLL-KY-2026(047）
- Conditions
- Colorectal Cancer
- Keywords
- Colorectal Cancer, Epidemiology, Prognostic Factors, Survival, Retrospective, Multicenter, Xinjiang, Shandong
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 500 participants (actual)
- Lead sponsor
- Qianfoshan HospitalUniversity, hospital or other
- Collaborators
- The Second Affiliated Hospital of Shandong First Medical University, Affiliated Hospital of Jining Medical University, Xinjiang Medical University
- Study start
- 1 Jan 2016 (actual)
- Primary completion
- 31 Dec 2020 (actual)
- Study completion
- 31 Dec 2020 (actual)
- First posted
- 13 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a multicenter, retrospective, cross-sectional observational study aiming to investigate the 5-year overall survival (OS) rate of colorectal cancer (CRC) patients in Xinjiang and Shandong provinces of China. A total of no less than 500 pathologically confirmed CRC patients from 7 medical centers during January 1, 2016 to December 31, 2020 will be enrolled. We will collect and analyze the demographic characteristics, lifestyle, clinical pathological features, treatment patterns and survival prognosis data of patients, explore the regional differences of CRC and its key prognostic factors, and construct a CRC prognostic prediction model. The results will provide theoretical guidance for clinical practice and the formulation of public health policies.
Detailed description
Colorectal cancer is one of the most common malignant tumors with obvious regional distribution differences in incidence and prognosis. There are significant differences in economic development, lifestyle, dietary structure and medical resource allocation between Xinjiang (western China) and Shandong (eastern China), which may lead to different epidemiological characteristics and prognosis of CRC patients in the two regions. This study will enroll CRC patients from 7 multicenters in Xinjiang and Shandong, collect retrospective clinical data including demographic information, pathological features, treatment modes and follow-up records, use statistical methods such as Kaplan-Meier survival analysis and Cox proportional hazard regression model to analyze the 5-year OS rate and prognostic factors of patients in the two regions, compare the regional differences of CRC, and construct a Nomogram prognostic prediction model. The study will provide a scientific basis for the personalized treatment and regional public health prevention and control of CRC.
Study design
- Observational model
- Case crossover
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group/Cohort Label 1：Xinjiang CRC Cohort | – | Other: Retrospective Data CollectionRetrospective collection and analysis of clinical, pathological and follow-up data of pathologically confirmed colorectal cancer patients from medical centers in Xinjiang region, including demographic characteristics, lifestyle, treatment patterns and 5-year overall survival status. |
| Group/Cohort Label 2：Shandong CRC Cohort | – | Other: Retrospective Data CollectionRetrospective collection and analysis of clinical, pathological and follow-up data of pathologically confirmed colorectal cancer patients from medical centers in Shandong region, including demographic characteristics, lifestyle, treatment patterns and 5-year overall survival status. |
Who may qualify
- Ages
- 18 to 120 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- This is a retrospective, cross-sectional, multicenter observational study. The study population includes patients pathologically diagnosed with colorectal adenocarcinoma between January 1, 2016 and December 31, 2020 from medical centers in Xinjiang Uygur Autonomous Region and Shandong Province. Patients aged 18 years and above with complete clinical, pathological, treatment and follow-up data will be included. The study aims to analyze the regional epidemiological characteristics and prognostic factors of colorectal cancer.
Key inclusion criteria (5 listed)
- 1. Pathologically confirmed colorectal adenocarcinoma.
- 2. Patients diagnosed between January 1, 2016 and December 31, 2020.
- 3. Age ≥ 18 years old.
- 4. Complete clinical, pathological, treatment and follow-up data available.
- 5. Patients from medical centers in Xinjiang and Shandong regions.
Key exclusion criteria (4 listed)
- 1. Other pathological types of malignant tumors except colorectal adenocarcinoma.
- 2. Patients with incomplete clinical data or lost to follow-up.
- 3. Patients with severe organ dysfunction or other malignant tumors that may affect survival.
- 4. Age < 18 years old.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Retrospective Data CollectionAlso: Retrospective Clinical Data Collection and Analysis for Colorectal CancerRetrospective collection, collation and statistical analysis of de-identified clinical, pathological, treatment and follow-up data of pathologically confirmed colorectal cancer patients from 7 medical centers in Xinjiang and Shandong provinces from January 1, 2016 to December 31, 2020. The collected data includes demographic characteristics, lifestyle, tumor clinical pathological features, treatment patterns and 5-year overall survival status, for the purpose of analyzing regional epidemiological characteristics and key prognostic factors of colorectal cancer. | Other | Group/Cohort Label 1：Xinjiang CRC Cohort, Group/Cohort Label 2：Shandong CRC Cohort |
Primary outcome
5-year Overall Survival
Time frame: 5 years
Five-year overall survival rate of patients with colorectal cancer, defined as the time from pathological diagnosis to death from any cause or last follow-up.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Apr 2026.
- Individual participant dataSharing planned: No. There is no plan to share individual participant data (IPD) from this study. Data will be used only for the purpose of this retrospective observational study and will not be shared with third parties.
Related trials for Colorectal Cancer
Not yet recruitingPhase 1
Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy
Colorectal Neoplasms, Neoplasms
Active, not recruiting
Streamlined Geriatric and Oncological Evaluation Based On IC Technology
Breast Cancer, Comorbidities and Coexisting Conditions
RecruitingObservational study
Pre- and On-treatment Multi-omics Profiling of Locally Advanced Rectal Cancer
Rectal Neoplasms
Enrolling by invitationObservational study
Natural History Study of Early Life Exposures in Agriculture (ELEA)
Prostate Cancer, Leukemia
RecruitingPhase 2
Tislelizumab in People With Colorectal Cancer
Colorectal Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Colorectal Cancer, run by Qianfoshan Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
5-year Overall Survival (time frame: 5 years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Apr 2026.