Endodontic TreatmentNCT07526818
Comparison of Manual and Mechanical Glide Path Techniques for Measuring Root Canal Length Using Standalone Apex Locator and an Endomotor With built-in Apex Locator.
A study testing Endomotor with built-in apex locator E Connect S+ and Electronic Apex locators in people with Endodontic Treatment, run by Dow University of Health Sciences at 1 site in Pakistan.
Trial summary
This study is designed to compare two commonly used methods for measuring the length of the root canal during root canal treatment. Accurate measurement of the root canal is very important because it helps dentists clean, shape, and fill the canal properly, which improves the success of the treatment and reduces the… Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Endodontic Treatment
- What is being tested?
- Endomotor with built-in apex locator E Connect S+ and Electronic Apex locators
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 104 participants
- Where
- 1 sitePakistan
- Study dates
- 26 Mar 2026to 25 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Both sex.
- Aged 18 to 60 years.
- Lower first permanent molars seeking root canal treatment.
- Teeth exhibiting symptomatic irreversible pulpitis with normal periapical tissues.
- Teeth with mature apex.
- 3 visible canals from orifice to apex.
- -
Who cannot join
- Teeth with metallic restorations or previous root treated teeth.
- Fractured , teeth with immature apices, or developmental anomalies.
- Systemic disease and immune deficiency.
- Canals where the mechanical glide path could not be established.
- Teeth with canal calcification or root resorption.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of Mechanical and Manual Glide Path Techniques for Electronic Working Length Measurement Using Built-in or Standalone Apex Locator: A Randomized Controlled Trial.
This study is designed to compare two commonly used methods for measuring the length of the root canal during root canal treatment. Accurate measurement of the root canal is very important because it helps dentists clean, shape, and fill the canal properly, which improves the success of the treatment and reduces the risk of complications.
In this study, two different techniques will be evaluated. The first method uses small hand instruments (manual technique) to create a smooth pathway inside the root canal before measuring its length. The second method uses a machine-assisted system (mechanical technique) that creates this pathway automatically. Both methods use special electronic devices called apex locators, which help determine the exact length of the root canal more accurately than traditional X-rays alone.
Read more
Participants in this study will be patients who require root canal treatment on lower molar teeth. If you agree to take part, you will receive standard root canal treatment similar to routine dental care. The only difference is the method used to prepare the canal and measure its length, which will be randomly assigned. This means neither you nor the dentist will choose the method, ensuring fair comparison.
The procedure will include taking dental X-rays, administering local anesthesia, cleaning and shaping the root canal, and filling it after measurement. All steps follow standard dental practices and safety protocols. Your treatment will not be compromised in any way by participating in the study.
The purpose of this research is to determine which method is more accurate, efficient, and reliable. The results may help improve future dental treatments by guiding dentists toward better techniques, ultimately benefiting patients through safer and more effective care.
Participation in this study is completely voluntary. You have the right to refuse participation or withdraw at any time without affecting your dental treatment. All personal and medical information will be kept confidential and used only for research purposes.
There are minimal risks involved, as all procedures are part of routine root canal treatment. You may not receive direct personal benefit, but your participation will contribute to improving dental care for others in the future.
- Conditions
- Endodontic Treatment
- Being tested
- Endomotor with built-in apex locator E Connect S+, Electronic Apex locators
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Endomotor with built-in apex locator E Connect S+Device
Creating Mechanical glide path using E-connect S+ with auto apical stop function, confirmed radiographically
Electronic Apex locatorsDevice
Manual glide path with size 10 K-file, working length determined by Root ZX II, confirmed radiographically.
| Study group | Role | What they receive |
|---|---|---|
| Group 1: Control | Active comparator | Group 1( Control): ): Manual glide path with size 10 K-file, working length determined by Root ZX II, confirmed radiographically. Receives: Device: Electronic Apex locators |
| Group 2: Intervention | Experimental | Group 2 (Intervention): Mechanical glide path using E-connect S+ with auto apical stop function, confirmed radiographically Receives: Device: Endomotor with built-in apex locator E Connect S+ |
What is being measured
The primary outcome is the main question the study is designed to answer.
Electronic working length (in millimeters) of root canals
The primary outcome measure is the electronic working length (in millimeters) of root canals as determined by either a standalone apex locator or an endomotor with built-in apex locator, following manual or mechanical glide path preparation.
Measured: 1 hour.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Apr 2026
- Study start26 Mar 2026
- Primary completion25 Mar 2027 (estimated)
- Study completion25 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Endodontic TreatmentStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 104 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Dow University of Health Sciences
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dr. Amrita, Dow University of Health Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07526818
- Sponsor's protocol ID
- IRB4481/DUHS/Approval/2026/113
- Status last verified
- Mar 2026
- First submitted
- 7 Apr 2026
- Last updated
- 27 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Individual participant data will not be shared due to participant privacy concerns, consent limitations, and regulatory requirements. Protecting confidentiality and adhering to ethical and legal standards takes priority.
Study at a glance
From the registry record, last updated by the sponsor on 27 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Mechanical and Manual Glide Path Techniques for Electronic Working Length Measurement Using Built-in or Standalone Apex Locator: A Randomized Controlled Trial.
- ClinicalTrials.gov ID
- NCT07526818
- Acronym / sponsor ID
- IRB4481/DUHS/Approval/2026/113
- Conditions
- Endodontic Treatment
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 104 participants (estimated)
- Lead sponsor
- Dow University of Health SciencesUniversity, hospital or other
- Study start
- 26 Mar 2026 (actual)
- Primary completion
- 25 Mar 2027 (estimated)
- Study completion
- 25 Mar 2027 (estimated)
- First posted
- 13 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is designed to compare two commonly used methods for measuring the length of the root canal during root canal treatment. Accurate measurement of the root canal is very important because it helps dentists clean, shape, and fill the canal properly, which improves the success of the treatment and reduces the risk of complications.
In this study, two different techniques will be evaluated. The first method uses small hand instruments (manual technique) to create a smooth pathway inside the root canal before measuring its length. The second method uses a machine-assisted system (mechanical technique) that creates this pathway automatically. Both methods use special electronic devices called apex locators, which help determine the exact length of the root canal more accurately than traditional X-rays alone.
Participants in this study will be patients who require root canal treatment on lower molar teeth. If you agree to take part, you will receive standard root canal treatment similar to routine dental care. The only difference is the method used to prepare the canal and measure its length, which will be randomly assigned. This means neither you nor the dentist will choose the method, ensuring fair comparison.
The procedure will include taking dental X-rays, administering local anesthesia, cleaning and shaping the root canal, and filling it after measurement. All steps follow standard dental practices and safety protocols. Your treatment will not be compromised in any way by participating in the study.
The purpose of this research is to determine which method is more accurate, efficient, and reliable. The results may help improve future dental treatments by guiding dentists toward better techniques, ultimately benefiting patients through safer and more effective care.
Participation in this study is completely voluntary. You have the right to refuse participation or withdraw at any time without affecting your dental treatment. All personal and medical information will be kept confidential and used only for research purposes.
There are minimal risks involved, as all procedures are part of routine root canal treatment. You may not receive direct personal benefit, but your participation will contribute to improving dental care for others in the future.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group 1: Control | Active comparator | Device: Electronic Apex locatorsGroup 1( Control): ): Manual glide path with size 10 K-file, working length determined by Root ZX II, confirmed radiographically. |
| Group 2: Intervention | Experimental | Device: Endomotor with built-in apex locator E Connect S+Group 2 (Intervention): Mechanical glide path using E-connect S+ with auto apical stop function, confirmed radiographically |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Both sex.
- Aged 18 to 60 years.
- Lower first permanent molars seeking root canal treatment.
- Teeth exhibiting symptomatic irreversible pulpitis with normal periapical tissues.
- Teeth with mature apex.
Key exclusion criteria (5 listed)
- Teeth with metallic restorations or previous root treated teeth.
- Fractured , teeth with immature apices, or developmental anomalies.
- Systemic disease and immune deficiency.
- Canals where the mechanical glide path could not be established.
- Teeth with canal calcification or root resorption.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Endomotor with built-in apex locator E Connect S+Creating Mechanical glide path using E-connect S+ with auto apical stop function, confirmed radiographically | Device | Group 2: Intervention |
| Electronic Apex locatorsManual glide path with size 10 K-file, working length determined by Root ZX II, confirmed radiographically. | Device | Group 1: Control |
Primary outcome
Electronic working length (in millimeters) of root canals
Time frame: 1 hour.
The primary outcome measure is the electronic working length (in millimeters) of root canals as determined by either a standalone apex locator or an endomotor with built-in apex locator, following manual or mechanical glide path preparation.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Apr 2026.
- Individual participant dataSharing planned: Undecided. Individual participant data will not be shared due to participant privacy concerns, consent limitations, and regulatory requirements. Protecting confidentiality and adhering to ethical and legal standards takes priority.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Endomotor with built-in apex locator E Connect S+ and Electronic Apex locators in people with Endodontic Treatment, run by Dow University of Health Sciences at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 27 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Electronic working length (in millimeters) of root canals (time frame: 1 hour.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Apr 2026.