Coronary Artery Bypass GraftingNCT07528989
Nurse Navigation Programs Affect to Anxiety, Perception of Quality Nursing Care and Stress Hormone Levels
A study testing Nursing navigation program in people with Coronary Artery Bypass Grafting and Preoperative Anxiety, run by Uludag University at 1 site in Turkey (Türkiye).
Trial summary
This study aims to evaluate the effect of a nurse-led preoperative navigation program on preoperative anxiety, perceived quality of perioperative nursing care, and serum cortisol levels in patients undergoing coronary artery bypass graft (CABG) surgery. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Coronary Artery Bypass Grafting, Preoperative Anxiety
- What is being tested?
- Nursing navigation program
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Nov 2023to 1 Nov 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- • who is 18 years of age or older
- Planned to undergo elective coronary artery bypass graft surgery,
- Who agrees to participate in the research,
- Whose cognitive functions are in place
- Communicable • Able to speak and understand Turkish,
Who cannot join
- Undergoing emergency surgery
- Who cannot speak and understand Turkish
- Having a psychiatric diagnosis
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of a Nurse-led Preoperative Navigation Program on Anxiety, Perceived Quality of Perioperative Nursing Care, and Stress Hormone Levels in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial
This study aims to evaluate the effect of a nurse-led preoperative navigation program on preoperative anxiety, perceived quality of perioperative nursing care, and serum cortisol levels in patients undergoing coronary artery bypass graft (CABG) surgery. A total of 60 patients scheduled for CABG surgery will be recruited from the cardiovascular surgery clinic and randomly assigned to either the intervention group (n=30) or the control group (n=30). Patients in the intervention group will receive a structured nurse-led preoperative navigation program, including verbal education and an animated video about the surgical and operating room process. Patients in the control group will receive standard perioperative care. Preoperative anxiety, serum cortisol and glucose levels, and perceived quality of perioperative nursing care will be assessed at specified time points.
Read the detailed description
This study is designed as a randomized controlled trial to evaluate the effect of a nurse-led preoperative navigation program in patients undergoing coronary artery bypass graft (CABG) surgery. Participants in the intervention group (n=30) will receive a structured nurse-led preoperative navigation program delivered approximately 7 days prior to surgery. The program includes verbal education about the surgical process and operating room procedures, along with an educational animated video that can be viewed repeatedly until the day of surgery. Participants in the control group (n=30) will receive standard perioperative care without the structured navigation program. Participants will be randomly assigned to either the intervention or control group. Outcome measures will be assessed at predefined time points.
- Being tested
- Nursing navigation program
- Keywords
- Nurse navigation, Preoperative anxiety, Perioperative nursing care, Coronary artery bypass grafting, Cortisol, Randomized controlled trial
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nursing navigation programOther
Participants will receive a structured nurse-led preoperative navigation program delivered approximately 7 days prior to surgery. The program consists of verbal counselling provided by the researcher about the surgical process and operating room procedures, along with an educational animated video designed to explain the perioperative process in a clear and patient-friendly manner.
The animated video (9 minutes and 56 seconds) includes information on the purpose of coronary artery bypass graft surgery, preoperative preparation, transfer to the operating room, the operating room environment and surgical team, and postoperative care in the intensive care unit. The video will be made available to patients and/or their relatives and can be viewed repeatedly until the day of surgery.
| Study group | Role | What they receive |
|---|---|---|
| Nursing navigation program | Experimental | Participants in the intervention group will receive a structured nurse-led preoperative navigation program. After admission to the cardiovascular surgery clinic, patients will receive verbal information about the surgical process and operating room procedures. In addition, an educational animated video will be provided and can be viewed repeatedly until the day of surgery. The intervention will be delivered approximately 7 days prior to surgery. Receives: Other: Nursing navigation program |
| Control | No intervention | Participants in the control group will receive standard perioperative care according to routine clinical practice. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Anxiety
Preoperative anxiety was measured using the Amsterdam Preoperative Anxiety and Information Scale (APAIS). The scale consists of 6 items rated on a 5-point Likert scale from 1 (not at all) to 5 (extremely). The total score ranges from 6 to 30, with higher scores indicating higher levels of anxiety.
Measured: At hospital admission and again 1 day before surgery
Secondary outcomes (2)
Perceived Quality of Perioperative Nursing Care
Perceived quality of perioperative nursing care was measured using the Good Perioperative Nursing Care Scale (GPNCS). The Turkish version of the scale consists of 32 items rated on a Likert-type scale from 0 to 5. The total score ranges from 0 to 160, with higher scores indicating better perceived quality of perioperative nursing care.
Measured: Postoperative day 3
Serum Cortisol
Serum cortisol levels were measured from fasting blood samples collected in the morning under standardized conditions (before mobilization and getting out of bed). Samples will be analyzed using electrochemiluminescence immunoassay (ECLIA), and results will be reported in µg/dL.
Measured: The day before surgery and the morning of surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Apr 2026
- Study start1 Nov 2023
- Primary completion1 Jun 2024
- Study completion1 Nov 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Coronary Artery Bypass GraftingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This study is designed as a randomized controlled trial to evaluate the effect of a nurse-led preoperative navigation program on preoperative anxiety, perceived quality of perioperative nursing care, and serum cortisol and glucose levels in patients undergoing coronary artery bypass graft (CABG) surgery. Participants will be randomly assigned to either the intervention or control group.
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Uludag University
- Sponsor type
- University, hospital or other
- Collaborators
- Bursa City Hospital
- Responsible party
- Principal investigator, Zeynep Gürer, Uludag University
- Investigators
- Neriman Akansel, professor, Study director, faculty member
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07528989
- Sponsor's protocol ID
- 20212411
- Status last verified
- Apr 2026
- First submitted
- 13 May 2024
- Last updated
- 5 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of a Nurse-led Preoperative Navigation Program on Anxiety, Perceived Quality of Perioperative Nursing Care, and Stress Hormone Levels in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07528989
- Acronym / sponsor ID
- 20212411
- Keywords
- Nurse navigation, Preoperative anxiety, Perioperative nursing care, Coronary artery bypass grafting, Cortisol, Randomized controlled trial
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Uludag UniversityUniversity, hospital or other
- Collaborators
- Bursa City Hospital
- Study start
- 1 Nov 2023 (actual)
- Primary completion
- 1 Jun 2024 (actual)
- Study completion
- 1 Nov 2024 (actual)
- First posted
- 14 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the effect of a nurse-led preoperative navigation program on preoperative anxiety, perceived quality of perioperative nursing care, and serum cortisol levels in patients undergoing coronary artery bypass graft (CABG) surgery. A total of 60 patients scheduled for CABG surgery will be recruited from the cardiovascular surgery clinic and randomly assigned to either the intervention group (n=30) or the control group (n=30). Patients in the intervention group will receive a structured nurse-led preoperative navigation program, including verbal education and an animated video about the surgical and operating room process. Patients in the control group will receive standard perioperative care. Preoperative anxiety, serum cortisol and glucose levels, and perceived quality of perioperative nursing care will be assessed at specified time points.
Detailed description
This study is designed as a randomized controlled trial to evaluate the effect of a nurse-led preoperative navigation program in patients undergoing coronary artery bypass graft (CABG) surgery. Participants in the intervention group (n=30) will receive a structured nurse-led preoperative navigation program delivered approximately 7 days prior to surgery. The program includes verbal education about the surgical process and operating room procedures, along with an educational animated video that can be viewed repeatedly until the day of surgery. Participants in the control group (n=30) will receive standard perioperative care without the structured navigation program. Participants will be randomly assigned to either the intervention or control group. Outcome measures will be assessed at predefined time points.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
- Model description
- This study is designed as a randomized controlled trial to evaluate the effect of a nurse-led preoperative navigation program on preoperative anxiety, perceived quality of perioperative nursing care, and serum cortisol and glucose levels in patients undergoing coronary artery bypass graft (CABG) surgery. Participants will be randomly assigned to either the intervention or control group.
| Arm | Type | Receives |
|---|---|---|
| Nursing navigation program | Experimental | Other: Nursing navigation programParticipants in the intervention group will receive a structured nurse-led preoperative navigation program. After admission to the cardiovascular surgery clinic, patients will receive verbal information about the surgical process and operating room procedures. In addition, an educational animated video will be provided and can be viewed repeatedly until the day of surgery. The intervention will be delivered approximately 7 days prior to surgery. |
| Control | No intervention | –Participants in the control group will receive standard perioperative care according to routine clinical practice. |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (5 listed)
- • who is 18 years of age or older
Key exclusion criteria (3 listed)
- Undergoing emergency surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nursing navigation programParticipants will receive a structured nurse-led preoperative navigation program delivered approximately 7 days prior to surgery. The program consists of verbal counselling provided by the researcher about the surgical process and operating room procedures, along with an educational animated video designed to explain the perioperative process in a clear and patient-friendly manner. The animated video (9 minutes and 56 seconds) includes information on the purpose of coronary artery bypass graft surgery, preoperative preparation, transfer to the operating room, the operating room environment and surgical team, and postoperative care in the intensive care unit. The video will be made available to patients and/or their relatives and can be viewed repeatedly until the day of surgery. | Other | Nursing navigation program |
Primary outcome
Anxiety
Time frame: At hospital admission and again 1 day before surgery
Preoperative anxiety was measured using the Amsterdam Preoperative Anxiety and Information Scale (APAIS). The scale consists of 6 items rated on a 5-point Likert scale from 1 (not at all) to 5 (extremely). The total score ranges from 6 to 30, with higher scores indicating higher levels of anxiety.
2 secondary outcomes
Perceived Quality of Perioperative Nursing Care
Time frame: Postoperative day 3
Serum Cortisol
Time frame: The day before surgery and the morning of surgery
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Neriman Akansel, professor study director
faculty member
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nursing navigation program in people with Coronary Artery Bypass Grafting and Preoperative Anxiety, run by Uludag University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Anxiety (time frame: At hospital admission and again 1 day before surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 May 2026.