Physical ActivitiesVITALNCT07529132
Changes in Energy Expenditure in Response to Physical Activity in Healthy Adults
An observational study of Physical Activities, run by Medical University of Bialystok at 1 site in Poland.
Trial summary
This study investigates how short, high-intensity body-weight exercises affect energy use in healthy young adults. The focus is on resting metabolic rate (RMR), total energy expenditure (TEE) and excess post-exercise oxygen consumption (EPOC), measured with a portable indirect calorimetry system (COSMED K5). Read more about this study
- Who is it for?
- Ages 18 to 30 years
- Conditions the study is for
- Physical Activities
- What is being tested?
- physical activity
- How many people
- 20 participants
- Where
- 1 sitePoland
- Study dates
- 1 Sep 2025to Jan 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- No healthy volunteers
- Adult
Study population: Healthy volunteers aged 18 to 30 years will be recruited from the academic community of the Medical University of Białystok, primarily students affiliated with the Student Research Group at the II Department of Pulmonary Diseases, Lung Cancer and Internal Medicine. Participants must be free of chronic diseases, musculoskeletal injuries, and active infections, and must meet standard medical screening criteria before enrollment.
Who may be able to join
- Age 18-30 years
- Healthy volunteers without chronic diseases
- Normal resting ECG (regular sinus rhythm, 60-90 bpm)
- Normal blood pressure according to ESC guidelines
- Ability and willingness to provide written informed consent
Who cannot join
- Chronic diseases or musculoskeletal injury within the past 6 months
- Use of tobacco or nicotine products within the past 6 months
- Blood donation >20 mL (except diagnostic) within the past 6 months
- Use of narcotics, sedatives, or dietary supplements (e.g., creatine) within the past 2 weeks
- Active infection, fever, or acute illness at the time of study
- Inability to comply with study instructions (dietary restrictions, abstinence from alcohol/caffeine, exercise restrictions)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Poland1 site, 1 recruiting
- Recruiting
II Departemnt of Lung Diseases, Lung Cancer, and Internal Medicine
Bialystok, Podlaskie Voivodeship, 15-540
Lukasz Minarowski, MD PhD, +48858316383, lukasz.minarowski@umb.edu.pl
About this study
Official title: Assessment of Changes in Energy Expanditure in Response to Short-term Physical Activity Measured by Indirect Calorymetry in Healthy Individuals
This study investigates how short, high-intensity body-weight exercises affect energy use in healthy young adults. The focus is on resting metabolic rate (RMR), total energy expenditure (TEE) and excess post-exercise oxygen consumption (EPOC), measured with a portable indirect calorimetry system (COSMED K5). Participants will be 14 volunteers, seven women and seven men aged 18 to 30 years, recruited from the academic community of the Medical University of Białystok. Each subject will first undergo basic screening, including ECG, blood pressure, and body composition. Measurements will be taken in three phases. In the resting phase, RMR will be recorded after fifteen minutes of quiet sitting. In the exercise phase, participants will perform squats, burpees, or a plank for one minute at maximum effort or sustained position while energy use is continuously monitored. In the recovery phase, EPOC will be measured immediately after exercise to capture short-term changes. Oxygen uptake, ventilation, heart rate, and oxygen saturation will be tracked throughout the session. Environmental conditions such as room temperature and humidity will be standardized, and participants will avoid caffeine, alcohol, and heavy physical activity at least 24 hours before testing. The main aim is to determine whether even one minute of exercise can meaningfully alter EPOC steady state parameters, and to compare the energy cost of different exercise types. The data will be analyzed in relation to anthropometric variables and cardiopulmonary function. Results are expected to improve understanding of short-term energy dynamics and may support more precise recommendations in pulmonary rehabilitation, cardiology, sports medicine, and nutrition. By providing reliable measurements of caloric cost in simple exercises, the study can help design safer and more effective training, rehabilitation, and weight control programs.
- Conditions
- Physical Activities
- Being tested
- physical activity
- Keywords
- resting metabolic rate, plank, squats, burpees, indirect calorymetry, energy expenditure, exercise physiology, pulmonary rehabilitation, post-exercise oxygen consumption
- Medical subject headings
- Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
physical activityDiagnostic test
Also called body-weight exercise, squats, burpees, plank
Participants perform short, body-weight exercises including squats, burpees, or plank while wearing a portable indirect calorimetry system (COSMED K5). Each activity lasts one minute and is carried out at maximum effort or sustained position. Energy expenditure, oxygen consumption, ventilation, and vital signs are continuously recorded during and immediately after the activity. Measurements are compared with resting metabolic rate obtained before and excess post-exercise oxygen consumption obtained after exercise to assess the acute impact of physical activity on energy use in healthy young adults.
What is being measured
The primary outcome is the main question the study is designed to answer.
Differences Between Pre- and Post-exercise Energy Expenditure Measurement
Resting metabolic rate (RMR) will be measured in kcal/min using the COSMED K5 portable indirect calorimetry system. Each participant will undergo a baseline measurement after 15 minutes of seated rest. Immediately following one minute of physical activity (squats, burpees, or plank) with continuous measurement of energy expenditure, then during restitution EPOC will be measured (in lO₂ or kcal) until values stabilize. The primary outcome is the difference between post-exercise energy expenditure and baseline, reflecting the acute impact of short-duration, high-intensity activity on energy metabolism in healthy young adults.
Measured: Baseline and immediately post-exercise (within 10-15 minutes).
Secondary outcomes (1)
Total Energy Expenditure (TEE) During Exercise
Resting metabolic rate (RMR) will be measured in kcal/min using the COSMED K5 portable indirect calorimetry system. Each participant will undergo a baseline measurement after 15 minutes of seated rest. Immediately following one minute of physical activity (squats, burpees, or plank) with continuous measurement of energy expenditure, then during restitution EPOC will be measured (in lO₂ or kcal) until values stabilize. The secondary outcome is a measure of energy expenditure during one minute of high-intensity activity in healthy young adults.
Measured: From the beginning to the end of performing the exercise (1 minute).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Apr 2026
- Study start1 Sep 2025
- Primary completionDec 2026 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Physical ActivitiesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Medical University of Bialystok
- Sponsor type
- University, hospital or other
- Collaborators
- University Teaching Hospital, Bialystok
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07529132
- Sponsor's protocol ID
- APK.002.256.2025
- Acronym
- VITAL
- Status last verified
- Oct 2026
- First submitted
- 7 Apr 2026
- Last updated
- 19 Oct 2026
- Results posted
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessment of Changes in Energy Expanditure in Response to Short-term Physical Activity Measured by Indirect Calorymetry in Healthy Individuals
- ClinicalTrials.gov ID
- NCT07529132
- Acronym / sponsor ID
- VITAL / APK.002.256.2025
- Conditions
- Physical Activities
- Keywords
- resting metabolic rate, plank, squats, burpees, indirect calorymetry, energy expenditure, exercise physiology, pulmonary rehabilitation
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- Medical University of BialystokUniversity, hospital or other
- Collaborators
- University Teaching Hospital, Bialystok
- Study start
- 1 Sep 2025 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 14 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study investigates how short, high-intensity body-weight exercises affect energy use in healthy young adults. The focus is on resting metabolic rate (RMR), total energy expenditure (TEE) and excess post-exercise oxygen consumption (EPOC), measured with a portable indirect calorimetry system (COSMED K5). Participants will be 14 volunteers, seven women and seven men aged 18 to 30 years, recruited from the academic community of the Medical University of Białystok. Each subject will first undergo basic screening, including ECG, blood pressure, and body composition. Measurements will be taken in three phases. In the resting phase, RMR will be recorded after fifteen minutes of quiet sitting. In the exercise phase, participants will perform squats, burpees, or a plank for one minute at maximum effort or sustained position while energy use is continuously monitored. In the recovery phase, EPOC will be measured immediately after exercise to capture short-term changes. Oxygen uptake, ventilation, heart rate, and oxygen saturation will be tracked throughout the session. Environmental conditions such as room temperature and humidity will be standardized, and participants will avoid caffeine, alcohol, and heavy physical activity at least 24 hours before testing. The main aim is to determine whether even one minute of exercise can meaningfully alter EPOC steady state parameters, and to compare the energy cost of different exercise types. The data will be analyzed in relation to anthropometric variables and cardiopulmonary function. Results are expected to improve understanding of short-term energy dynamics and may support more precise recommendations in pulmonary rehabilitation, cardiology, sports medicine, and nutrition. By providing reliable measurements of caloric cost in simple exercises, the study can help design safer and more effective training, rehabilitation, and weight control programs.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Healthy volunteers aged 18 to 30 years will be recruited from the academic community of the Medical University of Białystok, primarily students affiliated with the Student Research Group at the II Department of Pulmonary Diseases, Lung Cancer and Internal Medicine. Participants must be free of chronic diseases, musculoskeletal injuries, and active infections, and must meet standard medical screening criteria before enrollment.
Key inclusion criteria (5 listed)
- Age 18-30 years
- Healthy volunteers without chronic diseases
- Normal resting ECG (regular sinus rhythm, 60-90 bpm)
- Normal blood pressure according to ESC guidelines
- Ability and willingness to provide written informed consent
Key exclusion criteria (6 listed)
- Chronic diseases or musculoskeletal injury within the past 6 months
- Use of tobacco or nicotine products within the past 6 months
- Blood donation >20 mL (except diagnostic) within the past 6 months
- Use of narcotics, sedatives, or dietary supplements (e.g., creatine) within the past 2 weeks
- Active infection, fever, or acute illness at the time of study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| physical activityAlso: body-weight exercise, squats, burpees, plankParticipants perform short, body-weight exercises including squats, burpees, or plank while wearing a portable indirect calorimetry system (COSMED K5). Each activity lasts one minute and is carried out at maximum effort or sustained position. Energy expenditure, oxygen consumption, ventilation, and vital signs are continuously recorded during and immediately after the activity. Measurements are compared with resting metabolic rate obtained before and excess post-exercise oxygen consumption obtained after exercise to assess the acute impact of physical activity on energy use in healthy young adults. | Diagnostic test | – |
Primary outcome
Differences Between Pre- and Post-exercise Energy Expenditure Measurement
Time frame: Baseline and immediately post-exercise (within 10-15 minutes).
Resting metabolic rate (RMR) will be measured in kcal/min using the COSMED K5 portable indirect calorimetry system. Each participant will undergo a baseline measurement after 15 minutes of seated rest. Immediately following one minute of physical activity (squats, burpees, or plank) with continuous measurement of energy expenditure, then during restitution EPOC will be measured (in lO₂ or kcal) until values stabilize. The primary outcome is the difference between post-exercise energy expenditure and baseline, reflecting the acute impact of short-duration, high-intensity activity on energy metabolism in healthy young adults.
1 secondary outcome
Total Energy Expenditure (TEE) During Exercise
Time frame: From the beginning to the end of performing the exercise (1 minute).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Physical Activities, run by Medical University of Bialystok at 1 site in Poland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Poland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Lukasz Minarowski, MD PhD (+48858316383, lukasz.minarowski@umb.edu.pl), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Differences Between Pre- and Post-exercise Energy Expenditure Measurement (time frame: Baseline and immediately post-exercise (within 10-15 minutes).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026.