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Healthy Young AdultsNCT07529678

Differences in Autonomic Recovery Between Physically Active and Inactive Women Following an Automated Massage Chair Intervention

A study testing Massage chair in people with Healthy Young Adults and Physical Activity Levels, run by Universiti Sains Malaysia at 1 site in Malaysia.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The goal of this study is to investigate whether an automated massage chair can improve the body's recovery system in healthy young women (aged 19-26 years) who are either physically active or inactive. The main questions it aims to answer are: 1. Read more about this study

Who is it for?
Ages 19 to 26 years, women onlyHealthy volunteers can take part
What is being tested?
Massage chair
Type of treatment
Medical device
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
20 participants
Where
1 siteMalaysia
Study dates
23 Apr 2024to 18 Apr 2025
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 19 to 26 years
  • Women only
  • Healthy volunteers accepted
  • Adult

Participants in the physically active group were university athletes from various sports (athletics, football, volleyball, and badminton) with at least one year of competition experience at the university level and who engaged in supervised training sessions at least three times per week. Physically inactive were those who did not meet these criteria and were identified as having low physical activity levels based on the International Physical Activity Questionnaire (IPAQ).

Trial locations and contacts

1 site in 1 country.

Malaysia1 site
  • Exercise and Sports Science Laboratory

    Kubang Kerian, Kelantan, 16150

Other trials in Malaysia

About this study

Official title: The Effect of Automated Electronic Massage Chair on the Autonomic Nervous System of Female University Student-Athletes and Non- Athletes

The goal of this study is to investigate whether an automated massage chair can improve the body's recovery system in healthy young women (aged 19-26 years) who are either physically active or inactive.

The main questions it aims to answer are:

Read more
  1. Does a single session in an automated massage chair improve heart rate variability (HRV) as an indicator of stress, relaxation, and recovery balance?
  2. Do individuals who are more physically active recover better after using a massage chair compared to those who are inactive?

Researchers will compare the physically active group to the physically inactive group to see if baseline physical activity levels influence the short-term recovery effects of the massage at different time points.

Participants will:

  1. Complete a standardized 20-minute automated massage chair session using a preset program at a self-selected moderate intensity.
  2. Have their heart rate data collected at baseline, prior to the massage session.
  3. Undergo follow-up heart rate data collection at 24, 48, and 72 hours after the session to monitor short-term recovery changes.
Read the detailed description

Background and Rationale Massage therapy is widely utilized to promote overall health, alleviate stress, and facilitate recovery following physical exertion. A primary mechanism through which massage aids recovery is by modulating the autonomic nervous system (ANS). The ANS consists of the sympathetic nervous system (SNS), which drives the "fight-or-flight" stress response, and the parasympathetic nervous system (PNS), which governs "rest-and-digest" processes vital for tissue repair and cardiovascular recovery.In recent years, automated electric massage chairs (AEMCs) have surged in popularity as an accessible means to replicate therapist-delivered manual massage. Despite their widespread commercial use for health and wellness, research examining their physiological impacts-particularly on autonomic regulation-remains limited. Furthermore, while physically active individuals typically demonstrate greater autonomic flexibility and faster physiological recovery than inactive individuals, it is largely unknown if these baseline physical activity levels influence the body's acute response to an automated massage intervention.

Study Objective This study aims to evaluate the acute physiological effects of a single AEMC session on autonomic regulation among healthy female university students. By utilizing heart rate variability (HRV) as a non-invasive marker of sympathovagal balance, researchers will compare the physiological responses of physically active participants against those of inactive participants over a 72-hour recovery period.

Study Procedures Participants will be assigned to one of two groups based on their habitual physical activity levels: a physically active group (engaging in at least three supervised training sessions per week) and an inactive group (identified via the International Physical Activity Questionnaire as having low physical activity levels).

The study involves the following procedural sequence:

  1. Familiarization: Prior to the initial assessment, participants will complete a familiarization session to acclimate to the monitoring devices and the AEMC while it is both powered off and on.
  2. Baseline Assessment: On the experimental day, participants will be fitted with a wrist-worn heart rate monitor and a chest strap heart rate transmitter. Participants will sit in the powered-off AEMC for five minutes to capture baseline HRV data. During this time, they will be instructed to remain relaxed and minimize both body movements and communication.
  3. Intervention: Participants will be positioned in a reclined posture, with their upper bodies supported and legs and feet elevated to heart level. They will then undergo a 20-minute standardized "Recharge" program on the AEMC. This program delivers a continuous, moderate-intensity massage using kneading and rolling techniques focused on the back, neck, shoulders, forearms, and thighs. The intensity will be subjectively selected by the participant to a moderate level and adjusted via a Bluetooth-connected application to ensure suitable pressure.
  4. Post-Intervention Monitoring: Following the massage session, participants will be instructed to resume normal daily activities but must refrain from structured exercise for three days. Participants will return to the laboratory at 24, 48, and 72 hours post-session to have their HRV recorded. All follow-up HRV measurements will be recorded at the same time of day to control for circadian variations.

Data Analysis and Mechanisms Heart rate data will be synced and analyzed using specialized software to calculate frequency-domain HRV indices. The analysis will specifically look at the high-frequency (HF) component, the low-frequency (LF) component, and the LF/HF ratio. The HF component primarily reflects parasympathetic activity, whereas the LF component represents a mixture of sympathetic and parasympathetic influences. The LF/HF ratio serves as an index of autonomic balance, with lower values indicating a state of parasympathetic dominance and enhanced recovery capacity. Tracking these metrics across multiple time points will allow researchers to observe the timeline of short-term autonomic changes and determine if habitual physical activity primes individuals to derive greater physiological recovery benefits from automated massage chair therapy.

Being tested
Massage chair
Keywords
automated massage chair, Physically inactive, physically active, autonomic nervous system, heart rate variability, sympathetic nervous system, parasympathetic nervous system

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Massage chairDevice

    The intervention utilized the Ogawa Master Drive AI 2.0 massage chair, which is an advanced, fully automated, electrically powered unit featuring Bluetooth-enabled control via the Ogawa Wellness app.

Study groups in NCT07529678
Study groupRoleWhat they receive
Physically Inactive GroupSham comparatorPhysically inactive participants undergo a single 20-minute treatment utilizing a commercial automated electric massage chair. For the duration of the intervention, subjects rest in a heavily reclined position, allowing the device to fully support the head and torso while keeping the lower extremities elevated.The massage chair is programmed to execute the manufacturer's specific "Recharge" protocol. This setting applies a combination of mechanical kneading and rolling motions across the upper and lower back, cervical region, arms, and thighs.To ensure consistency in perceived physical exertion, the mechanical force is customized per user. Researchers calibrate the physical pressure through a wireless application, relying on the participant's verbal feedback to lock in a self-reported "moderate" intensity rating prior to the 20-minute session. Heart rate variability is measured at pre, post 24-, post 48-, and post 72-hours massage intervention.
Receives: Device: Massage chair
Physically Active GroupActive comparatorParticipants are active.The intervention consists of a single 20-minute standardized session in an automated electric massage chair. Participants are positioned in a reclined posture where the back of the chair is nearly parallel to the floor, with their hips and knees flexed at 90 degrees or more, and their legs and feet elevated to heart level.The session utilizes a preset "Recharge" program designed to deliver moderate-intensity massage therapy. The mechanical massage applies continuous, harmonized kneading and rolling techniques specifically targeting the back, neck, shoulders, forearms, and thighs.While the program is preset, participants subjectively self-select their perceived moderate pressure on a scale of 1 to 3. The massage intensity is then adjusted via Bluetooth using a paired application, ensuring the pressure is suitable and comfortable for each individual participant. Heart rate variability is measured at pre, post 24-, post 48-, and post 72-hours massage intervention.
Receives: Device: Massage chair

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Heart rate variability

    The primary outcome measures changes in autonomic nervous system regulation using frequency-domain indices of Heart Rate Variability (HRV). HRV is a non-invasive marker of sympathovagal balance.Three specific metrics are evaluated using Kubios software:

    1. High-Frequency (HF) power: Measured in normalized units (0.15-0.40 Hz). HF reflects parasympathetic (vagal) activity, which drives rest, relaxation, and recovery.
    2. Low-Frequency (LF) power: Measured in normalized units (0.04-0.15 Hz). LF indicates a mixture of sympathetic and parasympathetic nervous system influences.
    3. LF/HF Ratio: Calculated as an index of overall autonomic balance. Lower values denote greater parasympathetic dominance and more efficient recovery.These HRV outcomes are recorded at baseline, 24, 48, and 72 hours post-intervention to track short-term physiological recovery.

    Measured: Baseline, post 24-hours, post 48-hours, post 72-hours

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted14 Apr 2026
  2. Study start23 Apr 2024
  3. Primary completion1 Jul 2024
  4. Study completion18 Apr 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Other
Allocation
Non-randomised
Intervention model
Parallel groups
Model description
Two groups: 1. Physically Active 2. Physically Inactive Both groups receive the same intervention
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
20 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07529678
Sponsor's protocol ID
USM/JEPeM/KK/24010104
Status last verified
Apr 2026
First submitted
13 Aug 2025
Last updated
14 Apr 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: Participants indicated that their data should not be used for any purposes outside the current study, including future research or sharing with external agencies.

Publications

  • Chen YS, Lu WA, Clemente FM, Bezerra JP, Kuo CD. Increased Parasympathetic Activity by Foot Reflexology Massage after Repeated Sprint Test in Collegiate Football Players: A Randomised Controlled Trial. Sports (Basel). 2019 Nov 3;7(11):228. doi: 10.3390/sports7110228.

    PubMed 31684198
  • Yilmaz E, Aktop A, Abdioglu A, Melekoglu T, Nalbant M. The Effect of Heart Rate Variability Biofeedback on Recovery After Aerobic Exercise. Appl Psychophysiol Biofeedback. 2025 Mar;50(1):95-106. doi: 10.1007/s10484-024-09672-z. Epub 2024 Dec 4.

    PubMed 39630342
  • Miyagi R, Sasawaki Y, Shiotani H. The influence of short-term sedentary behavior on circadian rhythm of heart rate and heart rate variability. Chronobiol Int. 2019 Mar;36(3):374-380. doi: 10.1080/07420528.2018.1550422. Epub 2018 Dec 3.

    PubMed 30501447
  • Fazeli MS, Pourrahmat MM, Liu M, Guan L, Collet JP. The Effect of Head Massage on the Regulation of the Cardiac Autonomic Nervous System: A Pilot Randomized Crossover Trial. J Altern Complement Med. 2016 Jan;22(1):75-80. doi: 10.1089/acm.2015.0141. Epub 2015 Nov 12.

    PubMed 26562003
  • Tarvainen MP, Niskanen JP, Lipponen JA, Ranta-Aho PO, Karjalainen PA. Kubios HRV--heart rate variability analysis software. Comput Methods Programs Biomed. 2014;113(1):210-20. doi: 10.1016/j.cmpb.2013.07.024. Epub 2013 Aug 6.

    PubMed 24054542
  • Craig CL, Marshall AL, Sjostrom M, Bauman AE, Booth ML, Ainsworth BE, Pratt M, Ekelund U, Yngve A, Sallis JF, Oja P. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003 Aug;35(8):1381-95. doi: 10.1249/01.MSS.0000078924.61453.FB.

    PubMed 12900694
  • Mat Isar NEN, Abdul Halim MHZ, Ong MLY. Acute massage stimulates parasympathetic activation after a single exhaustive muscle contraction exercise. J Bodyw Mov Ther. 2022 Apr;30:105-111. doi: 10.1016/j.jbmt.2022.02.016. Epub 2022 Feb 7.

    PubMed 35500957
  • Forstenpointner J, Elman I, Freeman R, Borsook D. The omnipresence of autonomic modulation in health and disease. Prog Neurobiol. 2022 Mar;210:102218. doi: 10.1016/j.pneurobio.2022.102218. Epub 2022 Jan 13.

    PubMed 35033599
  • Xie J, Fu M, Liu T, Li S, Liu G, Wang J, Ji C, Zhang T. Clinical studies on the electric automatic massage therapy for recovery of acute sports fatigue. Technol Health Care. 2023;31(S1):185-197. doi: 10.3233/THC-236016.

    PubMed 37038791
  • Youn BY, Cho H, Joo S, Kim HJ, Kim JY. Utilization of massage chairs for promoting overall health and wellness: A rapid scoping review. Explore (NY). 2024 May-Jun;20(3):285-297. doi: 10.1016/j.explore.2023.10.002. Epub 2023 Oct 5.

    PubMed 37839928
  • Baek JY, Lee E, Gil B, Jung HW, Jang IY. Clinical effects of using a massage chair on stress measures in adults: A pilot randomized controlled trial. Complement Ther Med. 2022 Jun;66:102825. doi: 10.1016/j.ctim.2022.102825. Epub 2022 Mar 24.

    PubMed 35339652

Questions about this trial

What is this clinical trial studying?

A study testing Massage chair in people with Healthy Young Adults and Physical Activity Levels, run by Universiti Sains Malaysia at 1 site in Malaysia.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 14 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Malaysia. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Heart rate variability (time frame: Baseline, post 24-hours, post 48-hours, post 72-hours). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07529678, which also lists 11 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Apr 2026.

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