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HealhtyNCT07530731

Platforms Comparison Study - NIXOS-COMPARISON

A study testing administration of 15 neuro-ophtalmological tests per platform by video-oculography in people with Healhty, run by Bulbitech at 1 site in Norway.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The purpose of the study is to verify that BulbiCAM®, a video-oculography medical device, gives similar results regardless of the Operating System (OS) used. The study compares three platforms: Windows, Linux Ubuntu, and Linux NixOS. Read more about this study

Who is it for?
Ages 18 to 75 yearsHealthy volunteers can take part
Conditions the study is for
Healhty
What is being tested?
administration of 15 neuro-ophtalmological tests per platform by video-oculography
Type of treatment
Medical device
Could I receive a placebo?
No, everyone receives an active treatment
How many people
36 participants
Where
1 siteNorway
Study dates
1 Apr 2026to 8 May 2026
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 75 years
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Who may be able to join

  • Healthy adult age 18-75 years inclusive
  • Willing and able to provide informed consent
  • Able to understand and follow instructions (Norwegian or English)
  • Able to complete testing procedures

Who cannot join

  • Ophthalmic:
  • Visual disturbance and blindness of any cause, except for corrected refractive errors
  • Visual acuity worse than 1.0 logMAR in the tested eye (unable to focus on test stimuli)
  • History of eye surgery in the last 6 months
  • Visible abnormalities of the eye (subconjunctival hemorrhages, inflammation, deformed pupils)
  • Significant eyelid ptosis that would interfere with testing
Show all 15Show fewer
  • Pupils unable to respond normally to dilation/contraction due to nerve damage, mechanical damage, or medication
  • Neurological/Medical:
  • Physical or psychiatric disease which may disturb the measuring procedure
  • Unable to tolerate testing or maintain attention for ~80 minutes with rest periods
  • Unable to understand and follow instructions
  • Photosensitive epilepsy
  • Other:
  • Known alcoholic or drug dependency
  • Any condition that, in the investigator's judgment, would make the subject unsuitable for the study

Trial locations and contacts

1 site in 1 country.

Norway1 site
  • Bulbitech

    Trondheim

Other trials in Norway

About this study

Official title: Comparison of NixOS-based Neuro-Ophtalmic Testing Platform Versus Windows and Ubuntu-based Platforms

The purpose of the study is to verify that BulbiCAM®, a video-oculography medical device, gives similar results regardless of the Operating System (OS) used. The study compares three platforms: Windows, Linux Ubuntu, and Linux NixOS.

Conditions
Healhty
Being tested
administration of 15 neuro-ophtalmological tests per platform by video-oculography
Keywords
video-oculography, healthy control

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • administration of 15 neuro-ophtalmological tests per platform by video-oculographyDevice

    List of the 15 tests per platform:

    1. Calibration (functional screening)
    2. Fixation test
    3. Smooth pursuit
    4. Horizontal pro-saccade
    5. Multidirectional pro-saccade
    6. Pursuit acuity
    7. Pursuit contrast sensitivity
    8. Strobe contrast sensitivity
    9. Variable strobe
    10. Pupil dynamics
    11. RAPD
    12. Visual Field 16-points
    13. Ptosis
    14. Anti saccade
    15. Memory saccade
Study groups in NCT07530731
Study groupRoleWhat they receive
Ubuntu-NixOS-WindowsExperimentalorder of tested platforms
Receives: Device: administration of 15 neuro-ophtalmological tests per platform by video-oculography
Ubuntu - Windows - NixOSExperimentalorder of tested platforms
Receives: Device: administration of 15 neuro-ophtalmological tests per platform by video-oculography
Windows - Ubuntu - NixOSExperimentalorder of tested platforms
Receives: Device: administration of 15 neuro-ophtalmological tests per platform by video-oculography
Windiws - NixOS - UbuntuExperimentalorder of tested platforms
Receives: Device: administration of 15 neuro-ophtalmological tests per platform by video-oculography
NixOS - Ubuntu - WindowsExperimentalorder of tested platforms
Receives: Device: administration of 15 neuro-ophtalmological tests per platform by video-oculography
NixOS - Windows - UbuntuExperimentalorder of tested platforms
Receives: Device: administration of 15 neuro-ophtalmological tests per platform by video-oculography

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. No statistical difference between acuracy of horizontal pro-saccades when comparing the three platforms

    unit: %

    Measured: single visit at enrollment

  2. No statistical difference between peak velocity of horizontal pro-saccades when comparing the three platforms

    unit: degree/s

    Measured: Single visit at enrollment

  3. No statistical difference between acuracy of multidirectional pro-saccades when comparing the three platforms

    Unit: %

    Measured: Single visit at enrollment

  4. No statistical difference between peak velocity of multidirectional pro-saccades when comparing the three platforms

    unit: degree/s

    Measured: Single visit at enrollment

  5. No statistical difference between contrast sensitivity results when comparing the three platforms

    unit: Pelli-Robson

    Measured: Single visit at enrollment

  6. No statistical difference between variable strobe test results when comparing the three platforms

    unit: Pelli-Robson

    Measured: Single visit at enrollment

  7. No statistical difference between strobe contrast sensitivity results when comparing the three platforms

    unit: Pelli-Robson

    Measured: Single visit at enrollment

  8. No statistical difference between RAPD test result when comparing the three platforms

    no unit

    Measured: Single visit at enrollment

  9. No statistical difference between ptosis MRD1 and 2 when comparing the three platforms

    unit mm

    Measured: Single visit at enrollment

  10. No statistical difference between duration of fixation when comparing the three platforms

    Unit: ms

    Measured: Single visit at enrollment

  11. No statistical difference between the amplitude of intrusive saccades when comparing the three platforms

    Unit: degree

    Measured: Single visit at enrollment

  12. No statistical difference between the peak velocity of intrusive saccades when comparing the three platforms

    unit: degree/s

    Measured: Single visit at enrollment

  13. No statistical difference between the mean fixation time when comparing the three platforms

    unit: ms

    Measured: Single visit at enrollment

  14. No statistical difference between mean pupil size when comparing the three platforms

    unit: mm

    Measured: Single visit at enrollment

  15. No statistical difference between anti-saccade amplitudes when comparing the three platforms

    unit: degree

    Measured: Single visit at enrollment

  16. No statistical difference between anti-saccades peak velocity when comparing the three platforms

    unit: degree/s

    Measured: Single visit at enrollment

  17. No statistical difference between memory saccades accuracy when comparing the three platforms

    unit: %

    Measured: Single visit at enrollment

  18. No statistical difference between number of errors in memory saccades task when comparing the three platforms

    no unit

    Measured: Single visit at enrollment

  19. No statistical difference between memory saccades latencies when comparing Ubuntu and NixOS platforms

    unit: ms

    Measured: Single visit at enrollment

  20. No statistical difference between anti saccades latencies when comparing Ubuntu and NixOS platforms

    unit: ms

    Measured: Single visit at enrollment

  21. No statistical difference between saccadic reaction time in visual field test when comparing Ubuntu and NixOS platforms

    unit: ms

    Measured: Single visit at enrollment

  22. No statistical difference between pupil area when comparing Ubuntu and NixOS platforms

    unit: mm*s

    Measured: Single visit at enrollment

  23. No statistical difference between pupil diameters when comparing Ubuntu and NixOS platforms

    unit: mm

    Measured: Single visit at enrollment

  24. No statistical difference between pupil contraction latencies when comparing Ubuntu and NixOS platforms

    unit: ms

    Measured: Single visit at enrollment

  25. No statistical difference between peak velocity of pupil dilation when comparing Ubuntu and NixOS platforms

    unit: mm/s

    Measured: Single visit at enrollment

  26. No statistical difference between multidirectional pro-saccade latencies when comparing Ubuntu and NixOS platforms

    unit: ms

    Measured: Single visit at enrollment

  27. No statistical difference between horizontal pro-saccades latencies when comparing Ubuntu and NixOS platforms

    unit: ms

    Measured: Single visit at enrollment

  28. No statistical difference between smooth pursuit gain when comparing Ubuntu and NixOS platforms

    unit: %

    Measured: Single visit at enrollment

  29. No statistical difference between the calibration ratio when comparing the three platforms

    no unit

    Measured: Single visit at enrollment

  30. No statistical difference between pursuit acuity results when comparing Windows versus NixOS platforms

    unit: LogMAR

    Measured: Single visit at enrollment

Secondary outcomes (20)
  1. No statistical difference between pupil areas when comparing Windows versus Ubuntu using the corrective formulas for signal processing enhancement, modified stimulus and timing calibration

    Ubuntu and NixOS platforms contain an enhanced algorithm incorporating Fourier transform analysis of pupil data.

    The light used as a stimulus for the pupil dynamics test has been modified (in intensity, wavelength, and spatial characteristics) under Ubuntu/NixOS platform compared to the original stimulus under Windows A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: mm*s

    Measured: Single visit at enrollment

  2. No statistical difference between pupil diameters when comparing Windows versus Ubuntu using the corrective formulas for signal processing enhancement, modified stimulus and timing calibration

    Ubuntu and NixOS platforms contain an enhanced algorithm incorporating Fourier transform analysis of pupil data.

    The light used as a stimulus for the pupil dynamics test has been modified (in intensity, wavelength, and spatial characteristics) under Ubuntu/NixOS platform compared to the original stimulus under Windows A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: mm

    Measured: Single visit at enrollment

  3. No statistical difference between latency of pupil contraction when comparing Windows versus Ubuntu using the corrective formulas for signal processing enhancement, modified stimulus and timing calibration

    Ubuntu and NixOS platforms contain an enhanced algorithm incorporating Fourier transform analysis of pupil data.

    The light used as a stimulus for the pupil dynamics test has been modified (in intensity, wavelength, and spatial characteristics) under Ubuntu/NixOS platform compared to the original stimulus under Windows A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: ms

    Measured: Single visit at enrollment

  4. No statistical difference between smooth pursuit gain when comparing Windows versus Ubuntu using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: %

    Measured: Single visit at enrollment

  5. No statistical difference between horizontal pro-saccade latency when comparing Windows versus Ubuntu using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    Unit: ms

    Measured: Single visit at enrollment

  6. No statistical difference between multidirectional pro-saccade latencies when comparing Windows versus Ubuntu using the corrective formulas for timing calibration.

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    Unit: ms

    Measured: Single visit at enrollment

  7. No statistical difference between saccadic reaction times in visual field test when comparing Windows versus Ubuntu using the corrective formulas for timing calibration.

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    Unit: ms

    Measured: Single visit at enrollment

  8. No statistical difference between anti-saccade latencies when comparing Windows versus Ubuntu using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: ms

    Measured: Single visit at enrollment

  9. No statistical difference between memory saccades latencies when comparing Windows versus Ubuntu using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: ms

    Measured: Single visit at enrollment

  10. No statistical difference between peak velocity of pupil dilation when comparing Windows versus Ubuntu using the corrective formulas for signal processing enhancement and modified stimulus

    Ubuntu and NixOS platforms contain an enhanced algorithm incorporating Fourier transform analysis of pupil data.

    The light used as a stimulus for the pupil dynamics test has been modified (in intensity, wavelength, and spatial characteristics) under Ubuntu/NixOS platform compared to the original stimulus under Windows.

    Unit: mm/s

    Measured: Single visit at enrollment

  11. No statistical difference between pupil area when comparing Windows versus NixOS using the corrective formulas for signal processing enhancement, modified stimulus and timing calibration

    Ubuntu and NixOS platforms contain an enhanced algorithm incorporating Fourier transform analysis of pupil data.

    The light used as a stimulus for the pupil dynamics test has been modified (in intensity, wavelength, and spatial characteristics) under Ubuntu/NixOS platform compared to the original stimulus under Windows A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    Unit: mm*s

    Measured: Single visit at enrollment

  12. No statistical difference between pupil diameters when comparing Windows versus NixOS using the corrective formulas for signal processing enhancement, modified stimulus and

    Ubuntu and NixOS platforms contain an enhanced algorithm incorporating Fourier transform analysis of pupil data.

    The light used as a stimulus for the pupil dynamics test has been modified (in intensity, wavelength, and spatial characteristics) under Ubuntu/NixOS platform compared to the original stimulus under Windows A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: mm

    Measured: Single visit at enrollment

  13. No statistical difference between latencies of pupil contraction when comparing Windows versus NixOS using the corrective formulas for signal processing enhancement, modified stimulus and timing calibration

    Ubuntu and NixOS platforms contain an enhanced algorithm incorporating Fourier transform analysis of pupil data.

    The light used as a stimulus for the pupil dynamics test has been modified (in intensity, wavelength, and spatial characteristics) under Ubuntu/NixOS platform compared to the original stimulus under Windows A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    Unit: ms

    Measured: Single visit at enrollment

  14. No statistical difference between smooth pursuit gain when comparing Windows versus NixOS using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay. .

    Unit: %

    Measured: Single visit at enrollment

  15. No statistical difference between horizontal pro-saccades latencies when comparing Windows versus NixOS using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    Unit: ms

    Measured: Single visit at enrollment

  16. No statistical difference between multidirectional pro-saccades latencies when comparing Windows versus NixOS using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: ms

    Measured: Single visit at enrollment

  17. No statistical difference between saccadic reaction time fo visual field test when comparing Windows versus NixOS using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    unit: ms

    Measured: Single visit at enrollment

  18. No statistical difference between anti-saccades latencies when comparing Windows versus NixOS using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    Unit: ms

    Measured: Single visit at enrollment

  19. No statistical difference between memory saccades latencies when comparing Windows versus NixOS using the corrective formulas for timing calibration

    A timing calibration was implemented for Ubuntu and NixOS to improve accuracy results by accounting for the device delay.

    Unit: ms

    Measured: Single visit at enrollment

  20. No statistical difference between peak velocity of the pupil when comparing Windows versus NixOS using the corrective formulas for signal processing enhancement and modified stimulus

    Ubuntu and NixOS platforms contain an enhanced algorithm incorporating Fourier transform analysis of pupil data.

    The light used as a stimulus for the pupil dynamics test has been modified (in intensity, wavelength, and spatial characteristics) under Ubuntu/NixOS platform compared to the original stimulus under Windows Unit: mm/s

    Measured: Single visit at enrollment

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted15 Apr 2026
  2. Study start1 Apr 2026
  3. Primary completion8 May 2026
  4. Study completion8 May 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Other
Allocation
Randomised
Intervention model
Crossover
Model description
Each subject will be tested on each of the three platform and serve as its own comparator.
Masking
None (open label)
Enrolment
36 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07530731
Sponsor's protocol ID
NIXOS-COMPARISON
Status last verified
Jul 2026
First submitted
25 Mar 2026
Last updated
27 Jul 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided

Questions about this trial

What is this clinical trial studying?

A study testing administration of 15 neuro-ophtalmological tests per platform by video-oculography in people with Healhty, run by Bulbitech at 1 site in Norway.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 15 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 27 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Norway. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

No statistical difference between acuracy of horizontal pro-saccades when comparing the three platforms (time frame: single visit at enrollment). The study lists 30 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Jul 2026.

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