Healthy VolunteersPVFNCT07530900
Prediction of Visual Feedback Effects on Speech Motor Adaptation in Healthy Adults
A study testing Altered Auditory Feedback (AAF) and Visual-Acoustic Biofeedback in people with Healthy Volunteers and Speech, run by New York University at 1 site in United States.
Trial summary
This study examines whether individual differences in how speakers respond to hearing versus physical sensation during speech can predict who benefits most from visual feedback during a speech task. Read more about this study
- Who is it for?
- Ages 18 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy Volunteers, Speech
- What is being tested?
- Altered Auditory Feedback (AAF) and Visual-Acoustic Biofeedback
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 27 Apr 2026to 6 Aug 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age 18 to 45 years
- Self-reported English as dominant or equally dominant language (learned English by age 3)
- No self-reported history of significant speech, language, or hearing difficulty
- Pass pure-tone hearing screening at 25 dB HL
- Pass qualitative screening of speech, voice, and resonance based on connected speech sample
Who cannot join
- Learned English after age 3
- English is not a dominant language
- History of speech or language disorder, hearing loss, or neurodevelopmental disorder (e.g., autism spectrum disorder, Down syndrome)
- Failure to pass pure-tone hearing screening
- Failure to pass qualitative screening of speech, voice, and resonance
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Prediction of Visual Feedback Gain in Altered Auditory Feedback Tasks Using Computational Modeling
This study examines whether individual differences in how speakers respond to hearing versus physical sensation during speech can predict who benefits most from visual feedback during a speech task. Healthy adults will complete a series of tasks in which auditory feedback is altered in real time through headphones, with and without an added visual display of the speech signal. A computational model will be used to estimate how strongly each participant relies on hearing versus physical sensation when monitoring speech. The study will then test whether this individual profile predicts how much the visual display improves each participant's ability to respond to the altered feedback.
Read the detailed description
During speech, the brain relies on multiple sources of feedback, including auditory input and physical sensations from the tongue and lips, to monitor and adjust speech in real time. People differ in how much they rely on each of these feedback sources, and these individual differences may predict who benefits most from different types of technological support for speech learning.
This study examines whether a computational model of individual response to sensory feedback can predict how much a person benefits from the addition of real-time visual feedback during a speech task. Participants will complete a series of tasks in which auditory feedback of speech is altered in real time through headphones. A computational model is then used to estimate how strongly each participant relies on hearing versus physical sensation when monitoring speech. Participants then repeat the task with an added visual display showing the speech signal alongside a target, providing an additional source of feedback.
The primary question is whether the computational profile of sensory feedback use - specifically, whether a person relies more heavily on hearing or on physical sensation - predicts how much the visual display improves each participant's ability to respond to the altered feedback.
At baseline, participants complete two versions of an altered auditory feedback (AAF) task without visual feedback. The first uses a "fast adapt" design in which altered feedback is introduced and withdrawn repeatedly across short experimental runs; the second uses a standard adaptive design in which the altered feedback is introduced once and maintained for a longer run. Performance in both tasks is submitted to SimpleDIVA computational modeling to estimate participant-specific auditory and somatosensory response parameters. The use of two task variants allows evaluation of the stability of parameter estimates across elicitation conditions.
Participants then complete a standard adaptive AAF task with simultaneous real-time visual-acoustic biofeedback. The visual display presents the current audio playback signal (i.e., the altered signal) alongside a visual target derived from the participant's baseline production. The primary outcome measure is visual gain, defined as the within-participant difference in compensation magnitude between the auditory-visual feedback condition and the auditory-only condition of the standard adaptive AAF task.
The primary analysis uses linear regression to test whether SimpleDIVA parameters from the baseline phase predict the magnitude of visual gain. The predictor of primary interest is the ratio of auditory to total sensory weighting, reflecting the relative dominance of auditory versus somatosensory feedback. Baseline compensation magnitude in the auditory-only condition will be included as a covariate. A paired-samples t-test will also evaluate the overall effect of adding visual feedback on compensation magnitude across the sample.
- Conditions
- Healthy Volunteers, Speech
- Being tested
- Altered Auditory Feedback (AAF), Visual-Acoustic Biofeedback
- Keywords
- speech motor control, altered auditory feedback, biofeedback, sensorimotor adaptation, computational modeling
- Medical subject headings
- Speech
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Altered Auditory Feedback (AAF)Behavioural
Participants produce speech while hearing real-time altered auditory feedback delivered through headphones. Two task variants are administered: a fast-adapt design in which the altered feedback is introduced and withdrawn repeatedly, and a standard adaptive design in which the altered feedback is introduced once and maintained for an extended run. Administered to all participants as the baseline condition.
Visual-Acoustic BiofeedbackBehavioural
Participants perform the standard adaptive auditory feedback task with the addition of real-time visual display. The visual display presents the altered auditory signal alongside a visual target derived from the participant's baseline production. Administered to all participants following the auditory-only baseline phase.
| Study group | Role | What they receive |
|---|---|---|
| Altered Auditory Feedback With and Without Visual Feedback | Experimental | All participants complete altered auditory feedback tasks without visual feedback (baseline phase) followed by the same task with simultaneous real-time visual-acoustic biofeedback. Both conditions are administered within a single study visit. Receives: Behavioral: Altered Auditory Feedback (AAF); Behavioral: Visual-Acoustic Biofeedback |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean difference in F1 compensation magnitude between auditory-visual and auditory-only feedback conditions of standard adaptive feedback task
Visual gain is defined as the within-participant difference in acoustic compensation magnitude (measured from formant frequencies) between the auditory-visual feedback condition and the auditory-only condition of the standard adaptive feedback task. Greater visual gain indicates a larger compensatory response when visual feedback is available.
Measured: During study visit (Day 1)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Apr 2026
- Study start27 Apr 2026
- Primary completion6 Aug 2026
- Study completion6 Aug 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy VolunteersStudies of the same condition, open and under way.
- More trials run by New York UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- All participants complete both experimental conditions (auditory-only and auditory-visual feedback) in a within-subject design during a single study visit.
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- New York University
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Deafness and Other Communication Disorders (NIDCD)
- Responsible party
- Sponsor
- Investigators
- Tara McAllister, PhD, Principal investigator, New York University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07530900
- Sponsor's protocol ID
- PVF-Aim3
- Other IDs
- 1R01DC017476
- Acronym
- PVF
- Status last verified
- Apr 2026
- First submitted
- 2 Apr 2026
- Last updated
- 5 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Complete de-identified data and scripts to reproduce analyses reported in study manuscripts
Study at a glance
From the registry record, last updated by the sponsor on 5 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prediction of Visual Feedback Gain in Altered Auditory Feedback Tasks Using Computational Modeling
- ClinicalTrials.gov ID
- NCT07530900
- Acronym / sponsor ID
- PVF / PVF-Aim3
- Conditions
- Healthy Volunteers, Speech
- Keywords
- speech motor control, altered auditory feedback, biofeedback, sensorimotor adaptation, computational modeling
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- New York UniversityUniversity, hospital or other
- Collaborators
- National Institute on Deafness and Other Communication Disorders (NIDCD)
- Study start
- 27 Apr 2026 (actual)
- Primary completion
- 6 Aug 2026 (actual)
- Study completion
- 6 Aug 2026 (actual)
- First posted
- 15 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study examines whether individual differences in how speakers respond to hearing versus physical sensation during speech can predict who benefits most from visual feedback during a speech task. Healthy adults will complete a series of tasks in which auditory feedback is altered in real time through headphones, with and without an added visual display of the speech signal. A computational model will be used to estimate how strongly each participant relies on hearing versus physical sensation when monitoring speech. The study will then test whether this individual profile predicts how much the visual display improves each participant's ability to respond to the altered feedback.
Detailed description
During speech, the brain relies on multiple sources of feedback, including auditory input and physical sensations from the tongue and lips, to monitor and adjust speech in real time. People differ in how much they rely on each of these feedback sources, and these individual differences may predict who benefits most from different types of technological support for speech learning.
This study examines whether a computational model of individual response to sensory feedback can predict how much a person benefits from the addition of real-time visual feedback during a speech task. Participants will complete a series of tasks in which auditory feedback of speech is altered in real time through headphones. A computational model is then used to estimate how strongly each participant relies on hearing versus physical sensation when monitoring speech. Participants then repeat the task with an added visual display showing the speech signal alongside a target, providing an additional source of feedback.
The primary question is whether the computational profile of sensory feedback use - specifically, whether a person relies more heavily on hearing or on physical sensation - predicts how much the visual display improves each participant's ability to respond to the altered feedback.
At baseline, participants complete two versions of an altered auditory feedback (AAF) task without visual feedback. The first uses a "fast adapt" design in which altered feedback is introduced and withdrawn repeatedly across short experimental runs; the second uses a standard adaptive design in which the altered feedback is introduced once and maintained for a longer run. Performance in both tasks is submitted to SimpleDIVA computational modeling to estimate participant-specific auditory and somatosensory response parameters. The use of two task variants allows evaluation of the stability of parameter estimates across elicitation conditions.
Participants then complete a standard adaptive AAF task with simultaneous real-time visual-acoustic biofeedback. The visual display presents the current audio playback signal (i.e., the altered signal) alongside a visual target derived from the participant's baseline production. The primary outcome measure is visual gain, defined as the within-participant difference in compensation magnitude between the auditory-visual feedback condition and the auditory-only condition of the standard adaptive AAF task.
The primary analysis uses linear regression to test whether SimpleDIVA parameters from the baseline phase predict the magnitude of visual gain. The predictor of primary interest is the ratio of auditory to total sensory weighting, reflecting the relative dominance of auditory versus somatosensory feedback. Baseline compensation magnitude in the auditory-only condition will be included as a covariate. A paired-samples t-test will also evaluate the overall effect of adding visual feedback on compensation magnitude across the sample.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- All participants complete both experimental conditions (auditory-only and auditory-visual feedback) in a within-subject design during a single study visit.
| Arm | Type | Receives |
|---|---|---|
| Altered Auditory Feedback With and Without Visual Feedback | Experimental | Behavioral: Altered Auditory Feedback (AAF), Behavioral: Visual-Acoustic BiofeedbackAll participants complete altered auditory feedback tasks without visual feedback (baseline phase) followed by the same task with simultaneous real-time visual-acoustic biofeedback. Both conditions are administered within a single study visit. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age 18 to 45 years
- Self-reported English as dominant or equally dominant language (learned English by age 3)
- No self-reported history of significant speech, language, or hearing difficulty
- Pass pure-tone hearing screening at 25 dB HL
- Pass qualitative screening of speech, voice, and resonance based on connected speech sample
Key exclusion criteria (5 listed)
- Learned English after age 3
- English is not a dominant language
- History of speech or language disorder, hearing loss, or neurodevelopmental disorder (e.g., autism spectrum disorder, Down syndrome)
- Failure to pass pure-tone hearing screening
- Failure to pass qualitative screening of speech, voice, and resonance
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Altered Auditory Feedback (AAF)Participants produce speech while hearing real-time altered auditory feedback delivered through headphones. Two task variants are administered: a fast-adapt design in which the altered feedback is introduced and withdrawn repeatedly, and a standard adaptive design in which the altered feedback is introduced once and maintained for an extended run. Administered to all participants as the baseline condition. | Behavioural | Altered Auditory Feedback With and Without Visual Feedback |
| Visual-Acoustic BiofeedbackParticipants perform the standard adaptive auditory feedback task with the addition of real-time visual display. The visual display presents the altered auditory signal alongside a visual target derived from the participant's baseline production. Administered to all participants following the auditory-only baseline phase. | Behavioural | Altered Auditory Feedback With and Without Visual Feedback |
Primary outcome
Mean difference in F1 compensation magnitude between auditory-visual and auditory-only feedback conditions of standard adaptive feedback task
Time frame: During study visit (Day 1)
Visual gain is defined as the within-participant difference in acoustic compensation magnitude (measured from formant frequencies) between the auditory-visual feedback condition and the auditory-only condition of the standard adaptive feedback task. Greater visual gain indicates a larger compensatory response when visual feedback is available.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Nov 2026.
- Individual participant dataSharing planned: Yes. Complete de-identified data and scripts to reproduce analyses reported in study manuscripts
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Tara McAllister, PhD principal investigator
New York University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Altered Auditory Feedback (AAF) and Visual-Acoustic Biofeedback in people with Healthy Volunteers and Speech, run by New York University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean difference in F1 compensation magnitude between auditory-visual and auditory-only feedback conditions of standard adaptive feedback task (time frame: During study visit (Day 1)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Nov 2026.