Axillary BlockNCT07531407
The Effects of Dexamethasone and Ibuprofen on Postoperative Analgesia in Patients Undergoing Hand and Forearm Surgery With Axillary Brachial Plexus Block
An observational study of Axillary Block and Dexamethasone, run by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization at 1 site in Turkey (Türkiye).
Trial summary
This study aims to comparatively examine the effects of preemptive intravenous dexamethasone and intravenous ibuprofen use on the duration of analgesia in ultrasound-guided Axillary Brachial Plexus Block applications for patients undergoing hand and forearm surgery. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Axillary Block, Dexamethasone, Ibuprofen
- What is being tested?
- IV Dexamethasone 8mg and iv ibuprofen
- Type of treatment
- Injection or infusion
- How many people
- 79 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 May 2025to 31 Oct 2025
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients aged between 18 and 65 years, with ASA physical status I or II, who were scheduled for hand or forearm surgery, were included in the study.
Who may be able to join
- Patient's consent to participate in the study (Informed consent)
- Aged between 18 and 65 years
- ASA physical status I or II
- Being oriented and cooperative
- Scheduled to undergo hand or forearm surgery
- Body Mass Index (BMI) below 40 kg/m²
- Scheduled for axillary brachial plexus blockade
Who cannot join
- Patient's refusal to participate in the study
- Refusal of regional anesthesia
- Known allergy to local anesthetics
- Known allergy to ibuprofen
- Known allergy to dexamethasone
- Presence of coagulopathy
Show all 12Show fewer
- Local infection at the site of regional anesthesia application
- Presence of malignancy at the surgical site
- Diagnosis of diabetes mellitus
- Body Mass Index (BMI) of 40 kg/m² or above
- Duration of surgery exceeding 4 hours
- Administration of opioid medication during the preoperative or intraoperative period
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Prof. Dr. Cemil Tascioglu City Hospital
Istanbul, 34384
About this study
This study aims to comparatively examine the effects of preemptive intravenous dexamethasone and intravenous ibuprofen use on the duration of analgesia in ultrasound-guided Axillary Brachial Plexus Block applications for patients undergoing hand and forearm surgery. Furthermore, investigating the relationship between the study drugs and the incidence of Postoperative Nausea and Vomiting and determining the time until the first use of rescue analgesic are also among the secondary objectives.
- Conditions
- Axillary Block, Dexamethasone, Ibuprofen, Hand Surgery, Forearm Surgery, Postoperative Analgesia
- Being tested
- IV Dexamethasone 8mg, iv ibuprofen
- Keywords
- Axillary Brachial Plexus Blockade, Hand and Forearm Surgery, Postoperative Analgesia, Intravenous Dexamethasone, Intravenous Ibuprofen
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
IV Dexamethasone 8mgDrug
Patients who are in group D had intravenouse 8 mg dexamethasone before axillary brachial plexus blockade.
iv ibuprofenDrug
Patients who are in group I had intravenouse 400 mg ibuprofen before axillary brachial plexus blockade.
| Study group | Role | What they receive |
|---|---|---|
| D | Patients who had intravenouse dexamethasone Receives: Drug: IV Dexamethasone 8mg | |
| I | Patients who had intravenouse ibuprofen Receives: Drug: iv ibuprofen |
What is being measured
The primary outcome is the main question the study is designed to answer.
Duration of analgesia
Duration of analgesia was defined as the time from the performance of the block until the patient's first report of pain.
Measured: 24 hours
Secondary outcomes (1)
Incidence of PONV
The incidence of PONV during the first 24 hours following the block administration will be evaluated.
Measured: 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Apr 2026
- Study start1 May 2025
- Primary completion31 Oct 2025
- Study completion31 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Axillary BlockStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 79 participants (actual)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ayşegül Bilen, Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07531407
- Sponsor's protocol ID
- SBU-ANES-BCC-01
- Status last verified
- May 2026
- First submitted
- 9 Apr 2026
- Last updated
- 22 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- Yes
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Dexamethasone and Ibuprofen on Postoperative Analgesia in Patients Undergoing Hand and Forearm Surgery With Axillary Brachial Plexus Block
- ClinicalTrials.gov ID
- NCT07531407
- Acronym / sponsor ID
- SBU-ANES-BCC-01
- Conditions
- Axillary Block, Dexamethasone, Ibuprofen, Hand Surgery, Forearm Surgery, Postoperative Analgesia
- Keywords
- Axillary Brachial Plexus Blockade, Hand and Forearm Surgery, Postoperative Analgesia, Intravenous Dexamethasone, Intravenous Ibuprofen
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 79 participants (actual)
- Lead sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital OrganizationUniversity, hospital or other
- Study start
- 1 May 2025 (actual)
- Primary completion
- 31 Oct 2025 (actual)
- Study completion
- 31 Oct 2025 (actual)
- First posted
- 15 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to comparatively examine the effects of preemptive intravenous dexamethasone and intravenous ibuprofen use on the duration of analgesia in ultrasound-guided Axillary Brachial Plexus Block applications for patients undergoing hand and forearm surgery. Furthermore, investigating the relationship between the study drugs and the incidence of Postoperative Nausea and Vomiting and determining the time until the first use of rescue analgesic are also among the secondary objectives.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Day
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| D | – | Drug: IV Dexamethasone 8mgPatients who had intravenouse dexamethasone |
| I | – | Drug: iv ibuprofenPatients who had intravenouse ibuprofen |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients aged between 18 and 65 years, with ASA physical status I or II, who were scheduled for hand or forearm surgery, were included in the study.
Key inclusion criteria (7 listed)
- Patient's consent to participate in the study (Informed consent)
- Aged between 18 and 65 years
- ASA physical status I or II
- Being oriented and cooperative
- Scheduled to undergo hand or forearm surgery
Key exclusion criteria (12 listed)
- Patient's refusal to participate in the study
- Refusal of regional anesthesia
- Known allergy to local anesthetics
- Known allergy to ibuprofen
- Known allergy to dexamethasone
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| IV Dexamethasone 8mgPatients who are in group D had intravenouse 8 mg dexamethasone before axillary brachial plexus blockade. | Drug | D |
| iv ibuprofenPatients who are in group I had intravenouse 400 mg ibuprofen before axillary brachial plexus blockade. | Drug | I |
Primary outcome
Duration of analgesia
Time frame: 24 hours
Duration of analgesia was defined as the time from the performance of the block until the patient's first report of pain.
1 secondary outcome
Incidence of PONV
Time frame: 24 hours
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 May 2026.
- Individual participant dataSharing planned: No
Related trials for Axillary Block
Not yet recruiting
Comparison of Serratus Posterior Superior Intercostal Plane Block and Rhomboid Intercostal Block in Patients Undergoing Breast Cancer Surgery
Breast Cancer, Lymph Node Dissection
Not yet recruiting
Effect of Serratus and Pectoralis II Plane Block Versus Pectoralis II Alone on Acute Postoperative Pain After Mastectomy
Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection
Not yet recruiting
Classic Versus Interfascial Axillary Block in Hand, Wrist, and Forearm Surgery
Nerve Block, Regional Anesthesia
Active, not recruitingPhase 4
Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.
Distal Radius Fractures, Fracture Dislocation
Recruiting
Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia in Mastectomy
Breast Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Axillary Block and Dexamethasone, run by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Duration of analgesia (time frame: 24 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 May 2026.