Chronic Neck PainNCT07531537
Respiratory Exercises Versus Deep Neck Flexor Training in Chronic Mechanical Neck Pain
A study testing Respiratoty exercises, Deep neck flexor training and conventional program in people with Chronic Neck Pain, run by Cairo University at 1 site in Egypt.
Trial summary
This study will be conducted to compare the effect of adding respiratory exercises versus deep neck flexor training to conventional program on pain, cervical ROM, cervical muscle endurance, function, and chest expansion in patients with chronic mechanical neck pain. Read more about this study
- Who is it for?
- Ages 18 to 35 years
- Conditions the study is for
- Chronic Neck Pain
- What is being tested?
- Respiratoty exercises, Deep neck flexor training and conventional program
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 66 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Mar 2026to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients have mechanical neck pain lasting longer than three months.
- The ages of patients range from 18 to 35 years.
- Patients are lifetime non-smoker and non-alcoholic.
Who cannot join
- History of trauma or cervical spine fractures.
- Previous spinal surgery.
- Any inflammatory pathology.
- Any cervical disc pathology and neurological signs.
- Malignancy.
- Cervical radiculopathy.
Show all 10Show fewer
- Rheumatoid arthritis.
- Pregnant female.
- Currently using muscle relaxation medication.
- History of respiratory and cardiovascular illness
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Taheel center for physiotherapy
Zagazig
ola ismail ibrahim, M.Sc., +201008283364, olaismailibrahim@gmail.com
karima abdelaty hassan, Ass.Prof., +201114032967, karima.abelaty@pt.cu.edu.eg
About this study
Official title: Effect of Respiratory Muscle Exercises Versus Deep Neck Flexor Training on Pain, Function and Neck Muscle Endurance in Patients With Chronic Mechanical Neck Pain
This study will be conducted to compare the effect of adding respiratory exercises versus deep neck flexor training to conventional program on pain, cervical ROM, cervical muscle endurance, function, and chest expansion in patients with chronic mechanical neck pain. Sixty-six (66) of both genders ranging in age from 18 to 35 years old, with a history of mechanical neck pain longer than 3 months (chronic neck pain) will be invited to participate in this study. Participants will be randomly assigned into one of the three experimental groups as follow:
Group A will receive respiratory exercises in form of diaphragmatic breathing \& respiratory muscle stretch gymnastics plus conventional program.
Read more
Group B will receive deep neck flexor training in the form of low-load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program.
Group C (control group) will receive conventional program in form of TENS, infrared, isometric neck strengthening exercises and stretching exercises.
Read the detailed description
Introduction:
Neck pain (NP) impacts the cervical motor system, posture, and movement. Motor output of cervical muscles is impaired. Muscles have decreased strength, endurance, and force steadiness and cervical muscle behavior is altered eg., decreased activity of deep postural muscles, reduced directional specificity, delayed onset of muscle responses and muscle fatigability. Patients with neck pain usually present with weak deep neck flexors and extensors, increased fatigability of superficial neck flexors, alterations in posture, limited range of motion, decreased proprioception and other psycho-social affections such as anxiety, depression, kinesiophobia, and catastrophizing. These factors are responsible for the predisposition of respiratory dysfunction in these patients.
Statement of the problem:
This study will be conducted to answer the following question: Does adding respiratory exercises or deep neck flexor training to conventional program have any effect on pain, ROM, cervical muscle endurance, function, and chest expansion?
Significance of the study:
The Global Burden of Disease Study stated that neck pain is globally the fourth largest physical complaint in years lived with a disability. The clinical practice guidelines recommended for patients with CNP interventions are: education, cervical mobilization and manipulation, thoracic manipulation, and mixed exercises for cervical and scapulothoracic regions, or an association of different interventions. Despite the high prevalence and significant impact of chronic neck pain, the optimal exercise-based intervention remains unclear. While previous research has investigated the benefits of conventional physical therapy, there is no study to date comparing the effect of respiratory exercises versus deep neck flexor training while adding to conventional program in the management of chronic neck pain patients. Therefore the current study will be conducted to compare the effectiveness of adding respiratory exercises versus deep neck flexor training to conventional program in patients with chronic neck pain.
Delimitations:
This study will be delimited to:
- Sixty-six patients of both genders, ranging in age from 18 to 35 years old, with a history of neck pain longer than 3 months (chronic neck pain).
- There will be three groups of twenty-two patients for each group; Group (A) will receive respiratory exercises in the form of diaphragmatic breathing \& respiratory muscle stretch gymnastics plus conventional program in form of TENS, infrared, isometric strengthening and stretching exercises, Group (B) who will receive deep neck flexor training in form of low load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program in form of TENS, infrared, isometric strengthening and stretching exercises \& Group (C) who will receive combination of respiratory exercises and deep neck flexor training plus conventional program in form of TENS, infrared, isometric strengthening and stretching exercises for two times per week for 8 weeks.
- Neck pain will be measured by a visual analogue scale (VAS).
- The ACROM will be measured using a cervical range of motion device.
- Deep neck flexor endurance of cervical flexion will be assessed with the cranio-cervical flexion test using feedback from an air-filled pressure sensor.
- Neck function will be assessed with Arabic version of Neck Disability Index (NDI).
- Chest expansion will be assessed with measuring tape.
- Conditions
- Chronic Neck Pain
- Being tested
- Respiratoty exercises, Deep neck flexor training, conventional program
- Keywords
- chronic neck pain, deep neck flexor training, respiratory exercises
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Respiratoty exercisesOther
respiratory exercises in form of diaphragmatic breathing \& respiratory muscle stretch gymnastics plus conventional program
Deep neck flexor trainingOther
deep neck flexor training in the form of low-load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program
conventional programOther
conventional program in form of TENS, infrared, isometric neck strengthening exercises and stretching exercises
| Study group | Role | What they receive |
|---|---|---|
| Respiratory exercises group | Experimental | 22 male and female patients with chronic mechanical neck pain who will receive respiratory exercises in form of diaphragmatic breathing \& respiratory muscle stretch gymnastics plus conventional program. Receives: Other: Respiratoty exercises |
| Deep neck flexor training group | Experimental | 22 male and female patients with chronic mechanical neck pain who will receive deep neck flexor training in the form of low-load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program Receives: Other: Deep neck flexor training |
| control group | Experimental | 22 male and female patients with chronic mechanical neck pain who will receive conventional program in form of TENS, infrared, isometric neck strengthening exercises and stretching exercises Receives: Other: conventional program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Neck pain
pain will be assessed by visual analogue scale
Measured: From enrollment to the end of treatment at 8 weeks
Cervical ROM
cervical ROM will be assessed by CROM device
Measured: From enrollment to the end of treatment at 8 weeks
Neck muscle endurance
Neck muscle endurance will be assessed by crainiocervical flexion test using feedback from pressure sensor
Measured: From enrollment to the end of treatment at 8 weeks
Chest expansion
chest expansion will be assessed by taping measurement
Measured: From enrollment to the end of treatment at 8 weeks
Neck function
Neck function will be assessed by neck disability index, Arabic version
Measured: From enrollment to the end of treatment at 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Apr 2026
- Study start10 Mar 2026
- Primary completionOct 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Neck PainStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- single blinded randomized control trial
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 66 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Karima Abdelaty Hassan, Cairo University
- Investigators
- karima abdelaty hassan, Ass. Prof., Study director, Cairo Universitydina sayed abdullah, lecturer, Study director, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07531537
- Sponsor's protocol ID
- Chronic Mechanical Neck Pain
- Status last verified
- Apr 2026
- First submitted
- 3 Apr 2026
- Last updated
- 22 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 22 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Respiratory Muscle Exercises Versus Deep Neck Flexor Training on Pain, Function and Neck Muscle Endurance in Patients With Chronic Mechanical Neck Pain
- ClinicalTrials.gov ID
- NCT07531537
- Acronym / sponsor ID
- Chronic Mechanical Neck Pain
- Conditions
- Chronic Neck Pain
- Keywords
- chronic neck pain, deep neck flexor training, respiratory exercises
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 66 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 10 Mar 2026 (actual)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 15 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will be conducted to compare the effect of adding respiratory exercises versus deep neck flexor training to conventional program on pain, cervical ROM, cervical muscle endurance, function, and chest expansion in patients with chronic mechanical neck pain. Sixty-six (66) of both genders ranging in age from 18 to 35 years old, with a history of mechanical neck pain longer than 3 months (chronic neck pain) will be invited to participate in this study. Participants will be randomly assigned into one of the three experimental groups as follow:
Group A will receive respiratory exercises in form of diaphragmatic breathing \& respiratory muscle stretch gymnastics plus conventional program.
Group B will receive deep neck flexor training in the form of low-load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program.
Group C (control group) will receive conventional program in form of TENS, infrared, isometric neck strengthening exercises and stretching exercises.
Detailed description
Introduction:
Neck pain (NP) impacts the cervical motor system, posture, and movement. Motor output of cervical muscles is impaired. Muscles have decreased strength, endurance, and force steadiness and cervical muscle behavior is altered eg., decreased activity of deep postural muscles, reduced directional specificity, delayed onset of muscle responses and muscle fatigability. Patients with neck pain usually present with weak deep neck flexors and extensors, increased fatigability of superficial neck flexors, alterations in posture, limited range of motion, decreased proprioception and other psycho-social affections such as anxiety, depression, kinesiophobia, and catastrophizing. These factors are responsible for the predisposition of respiratory dysfunction in these patients.
Statement of the problem:
This study will be conducted to answer the following question: Does adding respiratory exercises or deep neck flexor training to conventional program have any effect on pain, ROM, cervical muscle endurance, function, and chest expansion?
Significance of the study:
The Global Burden of Disease Study stated that neck pain is globally the fourth largest physical complaint in years lived with a disability. The clinical practice guidelines recommended for patients with CNP interventions are: education, cervical mobilization and manipulation, thoracic manipulation, and mixed exercises for cervical and scapulothoracic regions, or an association of different interventions. Despite the high prevalence and significant impact of chronic neck pain, the optimal exercise-based intervention remains unclear. While previous research has investigated the benefits of conventional physical therapy, there is no study to date comparing the effect of respiratory exercises versus deep neck flexor training while adding to conventional program in the management of chronic neck pain patients. Therefore the current study will be conducted to compare the effectiveness of adding respiratory exercises versus deep neck flexor training to conventional program in patients with chronic neck pain.
Delimitations:
This study will be delimited to:
- Sixty-six patients of both genders, ranging in age from 18 to 35 years old, with a history of neck pain longer than 3 months (chronic neck pain).
- There will be three groups of twenty-two patients for each group; Group (A) will receive respiratory exercises in the form of diaphragmatic breathing \& respiratory muscle stretch gymnastics plus conventional program in form of TENS, infrared, isometric strengthening and stretching exercises, Group (B) who will receive deep neck flexor training in form of low load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program in form of TENS, infrared, isometric strengthening and stretching exercises \& Group (C) who will receive combination of respiratory exercises and deep neck flexor training plus conventional program in form of TENS, infrared, isometric strengthening and stretching exercises for two times per week for 8 weeks.
- Neck pain will be measured by a visual analogue scale (VAS).
- The ACROM will be measured using a cervical range of motion device.
- Deep neck flexor endurance of cervical flexion will be assessed with the cranio-cervical flexion test using feedback from an air-filled pressure sensor.
- Neck function will be assessed with Arabic version of Neck Disability Index (NDI).
- Chest expansion will be assessed with measuring tape.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 3
- Model description
- single blinded randomized control trial
| Arm | Type | Receives |
|---|---|---|
| Respiratory exercises group | Experimental | Other: Respiratoty exercises22 male and female patients with chronic mechanical neck pain who will receive respiratory exercises in form of diaphragmatic breathing \& respiratory muscle stretch gymnastics plus conventional program. |
| Deep neck flexor training group | Experimental | Other: Deep neck flexor training22 male and female patients with chronic mechanical neck pain who will receive deep neck flexor training in the form of low-load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program |
| control group | Experimental | Other: conventional program22 male and female patients with chronic mechanical neck pain who will receive conventional program in form of TENS, infrared, isometric neck strengthening exercises and stretching exercises |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Patients have mechanical neck pain lasting longer than three months.
- The ages of patients range from 18 to 35 years.
- Patients are lifetime non-smoker and non-alcoholic.
Key exclusion criteria (10 listed)
- History of trauma or cervical spine fractures.
- Previous spinal surgery.
- Any inflammatory pathology.
- Any cervical disc pathology and neurological signs.
- Malignancy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Respiratoty exercisesrespiratory exercises in form of diaphragmatic breathing \& respiratory muscle stretch gymnastics plus conventional program | Other | Respiratory exercises group |
| Deep neck flexor trainingdeep neck flexor training in the form of low-load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program | Other | Deep neck flexor training group |
| conventional programconventional program in form of TENS, infrared, isometric neck strengthening exercises and stretching exercises | Other | control group |
Primary outcome
Neck pain
Time frame: From enrollment to the end of treatment at 8 weeks
pain will be assessed by visual analogue scale
Cervical ROM
Time frame: From enrollment to the end of treatment at 8 weeks
cervical ROM will be assessed by CROM device
Neck muscle endurance
Time frame: From enrollment to the end of treatment at 8 weeks
Neck muscle endurance will be assessed by crainiocervical flexion test using feedback from pressure sensor
Chest expansion
Time frame: From enrollment to the end of treatment at 8 weeks
chest expansion will be assessed by taping measurement
Neck function
Time frame: From enrollment to the end of treatment at 8 weeks
Neck function will be assessed by neck disability index, Arabic version
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Apr 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
karima abdelaty hassan, Ass. Prof. study director
Cairo University
dina sayed abdullah, lecturer study director
Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Respiratoty exercises, Deep neck flexor training and conventional program in people with Chronic Neck Pain, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 22 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact ola ismail ibrahim, M.Sc. (+201008283364, olaismailibrahim@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Neck pain (time frame: From enrollment to the end of treatment at 8 weeks). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Apr 2026.