Sensation Diminished, PinprickNCT07533409
Tactile and Pain Sensory Thresholds and Hand Grip Strength
An observational study of Sensation Diminished, Pinprick and Pain, run by Sultan 1. Murat State Hospital at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study was to compare fingertip tactile sensation, hand and finger grip strength, and hand pain thresholds in children diagnosed with specific learning disorder with impairment in written expression and healthy controls. Read more about this study
- Who is it for?
- Ages 6 to 12 yearsHealthy volunteers can take part
- Conditions the study is for
- Sensation Diminished, Pinprick, Pain, Specific Learning Disorder, With Impairment in Written Expression
- What is being tested?
- Treatment outcome
- How many people
- 66 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 10 Apr 2026to 4 Sep 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 12 years
- All sexes
- Healthy volunteers accepted
- Child
Study population: The study will include 33 children diagnosed with specific learning disorder with impairment in written expression and 33 healty control children.
Who may be able to join
- Age between 6 and 12 years
- Clinically normal intellectual functioning
- Willingness to participate in the study on a voluntary basis
- Absence of any systemic disease
- Right-hand dominance
- Exclusion Criteria for specific learning disorder with impairment in written expression:
Show all 14Show fewer
- Presence of verbal or visual communication problems
- History of perinatal complications or physical head trauma
- Presence of psychiatric disorders other than specific learning disorder according to the DSM-5 diagnostic criteria
- History of known chronic physical or neurological disease (such as cerebral palsy, diabetes, epilepsy, autoimmune disease, liver failure, or kidney failure)
- Presence of substance or alcohol use disorder
- Diagnosis of a genetic disorder
- Previous surgery involving the hand region
- Presence of infection and/or sensory deficit in the hand region
Who cannot join
- Presence of any psychiatric disorder according to the DSM-5 diagnostic criteria
- Presence of verbal or visual communication problems
- History of perinatal complications or physical head trauma
- History of known chronic physical or neurological disease (such as cerebral palsy, diabetes, epilepsy, autoimmune disease, liver failure, or kidney failure)
- Presence of substance or alcohol use disorder
- Diagnosis of a genetic disorder
- Previous surgery involving the hand region
- Presence of infection and/or sensory deficit in the hand region
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of Tactile and Pain Sensory Thresholds and Hand Grip Strength in Children Diagnosed With Specific Learning Disorder With Impairment in Written Expression and Healthy Controls
The aim of this study was to compare fingertip tactile sensation, hand and finger grip strength, and hand pain thresholds in children diagnosed with specific learning disorder with impairment in written expression and healthy controls.
- Conditions
- Sensation Diminished, Pinprick, Pain, Specific Learning Disorder, With Impairment in Written Expression
- Being tested
- Treatment outcome
- Medical subject headings
- Somatosensory Disorders, Pain, Specific Learning Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Treatment outcomeOther
The participants' fingertip light touch and pain sensory thresholds, as well as hand and fingertip pinch strength, will be evaluated.
| Study group | Role | What they receive |
|---|---|---|
| Specific learning disorder with impairment in written expression | The children diagnosed with specific learning disorder with impairment in written expression according to the DSM-5 diagnostic criteria Receives: Other: Treatment outcome | |
| Control | The healthy children with no known medical condition Receives: Other: Treatment outcome |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fingertip light touch
The participants' light touch sensory thresholds will be assessed using Semmes-Weinstein monofilaments, which consist of calibrated synthetic monofilaments that differ in thickness and the amount of pressure applied. Measurements will be taken from the midpoint of the distal phalanx on the palmar surface of the first, second, and third fingers of the right hand. The test will be performed with the participants' eyes closed; starting with the smallest monofilament, contact will be applied to the test area and progressively larger monofilaments will be used. The test will be terminated when the participant first perceives the touch, and the corresponding value will be recorded.
Measured: Baseline
Hand grip strength
Hand grip strength will be assessed using a Jamar dynamometer (Patterson Medical, Green Bay, WI, USA). During the assessment, the participant will be seated with the shoulders adducted and in neutral rotation, the elbow flexed at 90°, the forearm in a neutral position, and the wrist between 0° and 30° of dorsiflexion. The evaluator will gently support the base of the dynamometer, place it in the participant's hand, and instruct the participant to squeeze as hard as possible. Three measurements of maximum voluntary contraction will be obtained for the right hand, and the highest value will be recorded in kilograms.
Measured: Baseline
Finger pinch strength
The pinch strength between the thumb and index finger of the participants' right hand will be assessed using a Jamar pinch gauge. During the assessment, the shoulder will be in adduction and neutral rotation, the elbow flexed at 90°, the forearm in mid-rotation, and the wrist in a neutral position. The participant will be instructed to squeeze the pinch gauge between the thumb and index finger as hard as possible. Three measurements of maximum voluntary contraction will be obtained for the right hand, and the highest value will be recorded in kilograms.
Measured: Baseline
Pressure pain threshold
The pressure pain threshold will be used to assess the patients' pain perception threshold. Pressure pain threshold will be measured using a manual pressure algometer (Baseline Dolorimeter®). The patients' pain perception thresholds will be measured at the right lateral epicondyle and at the midpoint of the web space between the first and second fingers. During the measurement, the algometer's flat circular probe with a surface area of 1.52 cm² will be placed on the relevant site, and pressure will be increased at a rate of 1 kg/second. The patients will be instructed to indicate the onset of pain by saying "stop" or by raising their hand when they begin to feel slight discomfort. For each reference site, the value will be calculated as the arithmetic mean of two measurements taken 30 seconds apart.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Apr 2026
- Study start10 Apr 2026
- Primary completion10 Aug 2026
- Study completion4 Sep 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Sensation Diminished, PinprickStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 66 participants (actual)
Sponsor and investigators
- Lead sponsor
- Sultan 1. Murat State Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Alper Mengi, Sultan 1. Murat State Hospital
- Investigators
- İbrahim Tiryaki, MD, Principal investigator, Sultan 1. Murat State Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07533409
- Sponsor's protocol ID
- 25/2/2026-Number:02/09
- Other IDs
- 25/2/2026-Number:02/09
- Status last verified
- Sep 2026
- First submitted
- 9 Apr 2026
- Last updated
- 9 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Tactile and Pain Sensory Thresholds and Hand Grip Strength in Children Diagnosed With Specific Learning Disorder With Impairment in Written Expression and Healthy Controls
- ClinicalTrials.gov ID
- NCT07533409
- Acronym / sponsor ID
- 25/2/2026-Number:02/09
- Conditions
- Sensation Diminished, Pinprick, Pain, Specific Learning Disorder, With Impairment in Written Expression
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 66 participants (actual)
- Lead sponsor
- Sultan 1. Murat State HospitalOther government
- Study start
- 10 Apr 2026 (actual)
- Primary completion
- 10 Aug 2026 (actual)
- Study completion
- 4 Sep 2026 (actual)
- First posted
- 16 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study was to compare fingertip tactile sensation, hand and finger grip strength, and hand pain thresholds in children diagnosed with specific learning disorder with impairment in written expression and healthy controls.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Specific learning disorder with impairment in written expression | – | Other: Treatment outcomeThe children diagnosed with specific learning disorder with impairment in written expression according to the DSM-5 diagnostic criteria |
| Control | – | Other: Treatment outcomeThe healthy children with no known medical condition |
Who may qualify
- Ages
- 6 to 12 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
- Study population
- The study will include 33 children diagnosed with specific learning disorder with impairment in written expression and 33 healty control children.
Key inclusion criteria (14 listed)
- Age between 6 and 12 years
- Clinically normal intellectual functioning
- Willingness to participate in the study on a voluntary basis
- Absence of any systemic disease
- Right-hand dominance
Key exclusion criteria (8 listed)
- Presence of any psychiatric disorder according to the DSM-5 diagnostic criteria
- Presence of verbal or visual communication problems
- History of perinatal complications or physical head trauma
- History of known chronic physical or neurological disease (such as cerebral palsy, diabetes, epilepsy, autoimmune disease, liver failure, or kidney failure)
- Presence of substance or alcohol use disorder
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Treatment outcomeThe participants' fingertip light touch and pain sensory thresholds, as well as hand and fingertip pinch strength, will be evaluated. | Other | Control, Specific learning disorder with impairment in written expression |
Primary outcome
Fingertip light touch
Time frame: Baseline
The participants' light touch sensory thresholds will be assessed using Semmes-Weinstein monofilaments, which consist of calibrated synthetic monofilaments that differ in thickness and the amount of pressure applied. Measurements will be taken from the midpoint of the distal phalanx on the palmar surface of the first, second, and third fingers of the right hand. The test will be performed with the participants' eyes closed; starting with the smallest monofilament, contact will be applied to the test area and progressively larger monofilaments will be used. The test will be terminated when the participant first perceives the touch, and the corresponding value will be recorded.
Hand grip strength
Time frame: Baseline
Hand grip strength will be assessed using a Jamar dynamometer (Patterson Medical, Green Bay, WI, USA). During the assessment, the participant will be seated with the shoulders adducted and in neutral rotation, the elbow flexed at 90°, the forearm in a neutral position, and the wrist between 0° and 30° of dorsiflexion. The evaluator will gently support the base of the dynamometer, place it in the participant's hand, and instruct the participant to squeeze as hard as possible. Three measurements of maximum voluntary contraction will be obtained for the right hand, and the highest value will be recorded in kilograms.
Finger pinch strength
Time frame: Baseline
The pinch strength between the thumb and index finger of the participants' right hand will be assessed using a Jamar pinch gauge. During the assessment, the shoulder will be in adduction and neutral rotation, the elbow flexed at 90°, the forearm in mid-rotation, and the wrist in a neutral position. The participant will be instructed to squeeze the pinch gauge between the thumb and index finger as hard as possible. Three measurements of maximum voluntary contraction will be obtained for the right hand, and the highest value will be recorded in kilograms.
Pressure pain threshold
Time frame: Baseline
The pressure pain threshold will be used to assess the patients' pain perception threshold. Pressure pain threshold will be measured using a manual pressure algometer (Baseline Dolorimeter®). The patients' pain perception thresholds will be measured at the right lateral epicondyle and at the midpoint of the web space between the first and second fingers. During the measurement, the algometer's flat circular probe with a surface area of 1.52 cm² will be placed on the relevant site, and pressure will be increased at a rate of 1 kg/second. The patients will be instructed to indicate the onset of pain by saying "stop" or by raising their hand when they begin to feel slight discomfort. For each reference site, the value will be calculated as the arithmetic mean of two measurements taken 30 seconds apart.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Sep 2026.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
İbrahim Tiryaki, MD principal investigator
Sultan 1. Murat State Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Sensation Diminished, Pinprick and Pain, run by Sultan 1. Murat State Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 14 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fingertip light touch (time frame: Baseline). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Sep 2026.