Bronchiectasis AdultYOGA-BRNCT07540936
Effects of an Online Yoga Program on Exercise Capacity and Quality of Life in Bronchiectasis Patients
A study testing Yoga Program in people with Bronchiectasis Adult and Yoga, run by Istanbul Medipol University Hospital at 1 site in Turkey (Türkiye).
Trial summary
Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life. Read more about this study
- Who is it for?
- Ages 30 to 55 years
- Conditions the study is for
- Bronchiectasis Adult, Yoga
- What is being tested?
- Yoga Program
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Jan 2025to 15 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 55 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Adults aged 30-55 years
- Diagnosed with non-cystic fibrosis bronchiectasis based on clinical and radiological findings
- Clinically stable condition
- No participation in a structured exercise program within the previous 3 months
- Voluntary agreement to participate
Who cannot join
- Presence of additional respiratory diseases
- Acute exacerbation or antibiotic use within the previous 4 weeks
- Physical or cognitive impairments limiting participation
- Age above 55 years
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Istanbul Medipol University, Faculty of Physiotherapy and Rehabilitation
Istanbul, Beykoz, 34810
About this study
Official title: Effects of an Eight-Week Online Yoga Program on Pulmonary Function, Exercise Capacity, Dyspnea, and Quality of Life in Patients With Non-Cystic Fibrosis Bronchiectasis: A Randomized Controlled Trial
Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life. Non-pharmacological interventions, such as exercise-based approaches, are increasingly used to support symptom management in these patients.
This study aimed to evaluate the effects of an eight-week online yoga program on exercise capacity, dyspnea severity, respiratory function, and quality of life in adults with non-cystic fibrosis bronchiectasis. A total of 70 participants were randomly assigned to either a yoga intervention group or a control group. The yoga group participated in supervised online sessions three times per week, including breathing exercises, postures, and relaxation techniques, while the control group received usual care without additional intervention.
Outcomes were assessed at baseline and after eight weeks using pulmonary function tests, the six-minute walk test (6MWT), the Modified Medical Research Council (mMRC) Dyspnea Scale, and the St. George's Respiratory Questionnaire (SGRQ). The study investigated whether yoga could provide a safe and effective complementary approach to improve symptoms and functional capacity in individuals with bronchiectasis.
Read the detailed description
Bronchiectasis is a chronic and progressive respiratory disorder characterized by irreversible bronchial dilatation, chronic airway inflammation, and recurrent infections. Patients commonly experience dyspnea, reduced exercise tolerance, fatigue, and impaired quality of life. In addition to pharmacological treatments, pulmonary rehabilitation and exercise-based interventions play an important role in symptom management and functional improvement.
Yoga is a mind-body intervention that integrates breathing exercises (pranayama), physical postures (asanas), and relaxation techniques. Previous studies in chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease, have demonstrated that yoga can improve respiratory muscle function, ventilatory efficiency, and overall well-being. However, evidence regarding its effectiveness in bronchiectasis remains limited.
This randomized controlled trial was conducted to investigate the effects of an eight-week online yoga program on pulmonary function, functional exercise capacity, dyspnea perception, and disease-specific quality of life in patients with non-cystic fibrosis bronchiectasis. Participants were recruited from the Department of Chest Diseases at Istanbul Medipol University between January 2025 and October 2025. Eligible participants were randomly assigned to either a yoga intervention group or a control group using a computer-generated randomization method.
The intervention consisted of 24 supervised online yoga sessions delivered over eight weeks (three sessions per week). Each session included structured breathing exercises, postural practices, and relaxation techniques designed to improve respiratory control, chest expansion, and physical awareness. The control group received standard care without additional intervention during the study period.
Outcome measures included spirometric parameters (FEV1, FVC, FEV1/FVC, PEF, FEF25-75), functional exercise capacity assessed by the six-minute walk test (6MWT), dyspnea severity measured by the Modified Medical Research Council (mMRC) Dyspnea Scale, and health-related quality of life evaluated using the St. George's Respiratory Questionnaire (SGRQ). Assessments were performed at baseline and after the eight-week intervention period.
The study aimed to determine whether yoga could serve as a safe, feasible, and effective complementary intervention to improve functional outcomes and symptom burden in individuals with bronchiectasis, particularly in the context of accessible and remote rehabilitation models.
- Conditions
- Bronchiectasis Adult, Yoga
- Being tested
- Yoga Program
- Keywords
- Yoga, Bronchiectasis, Pulmonary Rehabilitation, Quality of Life, Respiratory Function
- Medical subject headings
- Bronchiectasis, Respiratory Aspiration
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Yoga ProgramBehavioural
The intervention consisted of an eight-week online supervised yoga program including breathing exercises (pranayama), physical postures (asanas), and relaxation techniques. Sessions were conducted three times per week, totaling 24 sessions. The program was designed to improve respiratory control, chest expansion, and overall physical awareness.
| Study group | Role | What they receive |
|---|---|---|
| Yoga Group | Experimental | Participants in this group received an eight-week supervised online yoga program consisting of breathing exercises, postures (asanas), and relaxation techniques, performed three times per week (24 sessions in total). Receives: Behavioral: Yoga Program |
| Control Group | No intervention | Participants in this group received usual care without any additional intervention during the study period |
What is being measured
The primary outcome is the main question the study is designed to answer.
6-Minute Walk Distance (6MWT)
The change in functional exercise capacity assessed by the six-minute walk test (6MWT), measured as the distance (in meters) walked in six minutes.
Measured: Baseline and 8 weeks
Secondary outcomes (7)
Dyspnea Severity (mMRC Scale)
Dyspnea severity assessed using the Modified Medical Research Council (mMRC) Dyspnea Scale (0-4), where higher scores indicate greater breathlessness.
Measured: Baseline and 8 weeks
Health-Related Quality of Life (SGRQ)
Disease-specific quality of life assessed using the St. George's Respiratory Questionnaire (SGRQ), including symptom, activity, impact, and total scores (0-100 scale, higher scores indicate worse quality of life).
Measured: Baseline and 8 weeks
FEV1
Forced Expiratory Volume in 1 Second (FEV1), Pulmonary function assessed as forced expiratory volume in one second (FEV1) using spirometry.
Measured: Baseline and 8 weeks
FVC
Forced Vital Capacity (FVC), Pulmonary function assessed as forced vital capacity (FVC) using spirometry.
Measured: Baseline and 8 weeks
FEV1/FVC
FEV1/FVC Ratio, Pulmonary function assessed as the ratio of FEV1 to FVC using spirometry.
Measured: Baseline and 8 weeks
PEF
Peak Expiratory Flow (PEF), Pulmonary function assessed as peak expiratory flow (PEF) using spirometry.
Measured: Baseline and 8 weeks
FEF25-75
Forced Expiratory Flow (FEF25-75), Pulmonary function assessed as forced expiratory flow between 25% and 75% of FVC (FEF25-75) using spirometry.
Measured: Baseline and 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Apr 2026
- Study start15 Jan 2025
- Primary completion20 Jun 2025
- Study completion15 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Bronchiectasis AdultStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants were randomly assigned to either a yoga intervention group or a control group in a parallel design. The intervention group received an eight-week supervised online yoga program, while the control group received usual care without additional intervention.
- Masking
- None (open label)
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Istanbul Medipol University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, salih tan, Istanbul Medipol University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07540936
- Sponsor's protocol ID
- MEDIPOL-BR-YOGA
- Acronym
- YOGA-BR
- Status last verified
- Apr 2026
- First submitted
- 8 Apr 2026
- Last updated
- 21 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: "De-identified participant data, study protocol, and statistical analysis plan will be shared with researchers upon reasonable request after publication of the main study results. Requests should be sent to the corresponding author via email, and access will be granted following review and approval by the study steering committee."
Study at a glance
From the registry record, last updated by the sponsor on 21 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of an Eight-Week Online Yoga Program on Pulmonary Function, Exercise Capacity, Dyspnea, and Quality of Life in Patients With Non-Cystic Fibrosis Bronchiectasis: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07540936
- Acronym / sponsor ID
- YOGA-BR / MEDIPOL-BR-YOGA
- Conditions
- Bronchiectasis Adult, Yoga
- Keywords
- Yoga, Bronchiectasis, Pulmonary Rehabilitation, Quality of Life, Respiratory Function
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Istanbul Medipol University HospitalUniversity, hospital or other
- Study start
- 15 Jan 2025 (actual)
- Primary completion
- 20 Jun 2025 (actual)
- Study completion
- 15 Oct 2025 (actual)
- First posted
- 21 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Bronchiectasis is a chronic lung disease characterized by persistent cough, sputum production, shortness of breath, and recurrent infections, which can reduce physical capacity and quality of life. Non-pharmacological interventions, such as exercise-based approaches, are increasingly used to support symptom management in these patients.
This study aimed to evaluate the effects of an eight-week online yoga program on exercise capacity, dyspnea severity, respiratory function, and quality of life in adults with non-cystic fibrosis bronchiectasis. A total of 70 participants were randomly assigned to either a yoga intervention group or a control group. The yoga group participated in supervised online sessions three times per week, including breathing exercises, postures, and relaxation techniques, while the control group received usual care without additional intervention.
Outcomes were assessed at baseline and after eight weeks using pulmonary function tests, the six-minute walk test (6MWT), the Modified Medical Research Council (mMRC) Dyspnea Scale, and the St. George's Respiratory Questionnaire (SGRQ). The study investigated whether yoga could provide a safe and effective complementary approach to improve symptoms and functional capacity in individuals with bronchiectasis.
Detailed description
Bronchiectasis is a chronic and progressive respiratory disorder characterized by irreversible bronchial dilatation, chronic airway inflammation, and recurrent infections. Patients commonly experience dyspnea, reduced exercise tolerance, fatigue, and impaired quality of life. In addition to pharmacological treatments, pulmonary rehabilitation and exercise-based interventions play an important role in symptom management and functional improvement.
Yoga is a mind-body intervention that integrates breathing exercises (pranayama), physical postures (asanas), and relaxation techniques. Previous studies in chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease, have demonstrated that yoga can improve respiratory muscle function, ventilatory efficiency, and overall well-being. However, evidence regarding its effectiveness in bronchiectasis remains limited.
This randomized controlled trial was conducted to investigate the effects of an eight-week online yoga program on pulmonary function, functional exercise capacity, dyspnea perception, and disease-specific quality of life in patients with non-cystic fibrosis bronchiectasis. Participants were recruited from the Department of Chest Diseases at Istanbul Medipol University between January 2025 and October 2025. Eligible participants were randomly assigned to either a yoga intervention group or a control group using a computer-generated randomization method.
The intervention consisted of 24 supervised online yoga sessions delivered over eight weeks (three sessions per week). Each session included structured breathing exercises, postural practices, and relaxation techniques designed to improve respiratory control, chest expansion, and physical awareness. The control group received standard care without additional intervention during the study period.
Outcome measures included spirometric parameters (FEV1, FVC, FEV1/FVC, PEF, FEF25-75), functional exercise capacity assessed by the six-minute walk test (6MWT), dyspnea severity measured by the Modified Medical Research Council (mMRC) Dyspnea Scale, and health-related quality of life evaluated using the St. George's Respiratory Questionnaire (SGRQ). Assessments were performed at baseline and after the eight-week intervention period.
The study aimed to determine whether yoga could serve as a safe, feasible, and effective complementary intervention to improve functional outcomes and symptom burden in individuals with bronchiectasis, particularly in the context of accessible and remote rehabilitation models.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants were randomly assigned to either a yoga intervention group or a control group in a parallel design. The intervention group received an eight-week supervised online yoga program, while the control group received usual care without additional intervention.
| Arm | Type | Receives |
|---|---|---|
| Yoga Group | Experimental | Behavioral: Yoga ProgramParticipants in this group received an eight-week supervised online yoga program consisting of breathing exercises, postures (asanas), and relaxation techniques, performed three times per week (24 sessions in total). |
| Control Group | No intervention | –Participants in this group received usual care without any additional intervention during the study period |
Who may qualify
- Ages
- 30 to 55 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Adults aged 30-55 years
- Diagnosed with non-cystic fibrosis bronchiectasis based on clinical and radiological findings
- Clinically stable condition
- No participation in a structured exercise program within the previous 3 months
- Voluntary agreement to participate
Key exclusion criteria (4 listed)
- Presence of additional respiratory diseases
- Acute exacerbation or antibiotic use within the previous 4 weeks
- Physical or cognitive impairments limiting participation
- Age above 55 years
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Yoga ProgramThe intervention consisted of an eight-week online supervised yoga program including breathing exercises (pranayama), physical postures (asanas), and relaxation techniques. Sessions were conducted three times per week, totaling 24 sessions. The program was designed to improve respiratory control, chest expansion, and overall physical awareness. | Behavioural | Yoga Group |
Primary outcome
6-Minute Walk Distance (6MWT)
Time frame: Baseline and 8 weeks
The change in functional exercise capacity assessed by the six-minute walk test (6MWT), measured as the distance (in meters) walked in six minutes.
7 secondary outcomes
Dyspnea Severity (mMRC Scale)
Time frame: Baseline and 8 weeks
Health-Related Quality of Life (SGRQ)
Time frame: Baseline and 8 weeks
FEV1
Time frame: Baseline and 8 weeks
FVC
Time frame: Baseline and 8 weeks
FEV1/FVC
Time frame: Baseline and 8 weeks
PEF
Time frame: Baseline and 8 weeks
FEF25-75
Time frame: Baseline and 8 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Apr 2026.
- Individual participant dataSharing planned: Undecided. "De-identified participant data, study protocol, and statistical analysis plan will be shared with researchers upon reasonable request after publication of the main study results. Requests should be sent to the corresponding author via email, and access will be granted following review and approval by the study steering committee."
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Yoga Program in people with Bronchiectasis Adult and Yoga, run by Istanbul Medipol University Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
6-Minute Walk Distance (6MWT) (time frame: Baseline and 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Apr 2026.