Spinal Cord InjuriesNCT07549087
Motor Imagery Reaction Time in Individuals With Paraplegic Spinal Cord Injury
An observational study of Spinal Cord Injuries, run by Istanbul Physical Medicine Rehabilitation Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
Individuals aged 18-65 years who have been clinically diagnosed with spinal cord injury and have developed paraplegia will be included in the study. Demographic and clinical data of the participants, including age, sex, height, weight, etiology of injury, level of injury, duration of injury, and comorbidities, will be… Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Spinal Cord Injuries
- How many people
- 128 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 20 Apr 2026to 20 May 2026
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Adult, Older adult
Study population: The study population will consist of individuals aged 18-65 years with a clinical diagnosis of spinal cord injury and paraplegia who are followed in the inpatient and outpatient clinics of Istanbul Physical Therapy and Rehabilitation Training and Research Hospital. A healthy control group, matched for age and sex, will also be included. Participants will be recruited from patients presenting to the clinic during the study period and from healthy volunteers. All participants will be medically stable and able to complete the study assessments.
Who may be able to join
- Aged between 18 and 65 years
- Clinically diagnosed with spinal cord injury
- Presence of paraplegia
- Injury duration of at least 3 months
- Medically stable condition
- Ability to understand and follow study instructions
Show all 9Show fewer
- Ability to complete the computer-based left/right judgment task
- Willingness to participate and provide written informed consent
- For the healthy control group: age- and sex-compatible individuals without a history of neurological or major musculoskeletal disease, willing to participate and provide written informed consent
Who cannot join
- Tetraplegia
- History of other neurological disorders that may affect motor imagery performance
- Severe cognitive impairment or communication problems preventing proper participation
- Severe visual impairment uncorrected by glasses or lenses
- Upper or lower extremity musculoskeletal disorders, deformities, or recent injuries that may affect task performance
- Severe psychiatric disorder
- Uncontrolled pain or acute medical condition at the time of assessment
- Current participation in another interventional clinical study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Istanbul Physical Medicine and Rehabilitation Trainig and Research Hospital
Istanbul, Bahcelievler, 34100
About this study
Official title: Upper and Lower Extremity Motor Imagery Reaction Time in Individuals With Paraplegic Spinal Cord Injury: A Comparative Study With Healthy Controls
Individuals aged 18-65 years who have been clinically diagnosed with spinal cord injury and have developed paraplegia will be included in the study. Demographic and clinical data of the participants, including age, sex, height, weight, etiology of injury, level of injury, duration of injury, and comorbidities, will be recorded. In addition, disease-specific characteristics such as ambulation status, wheelchair use, presence of incontinence, and presence and severity of pain will be assessed. For the healthy control group, demographic data including age, sex, height, weight, and comorbidities will be recorded.
Motor imagery performance of the participants will be evaluated using a computer-based left/right judgment task. In this context, both upper extremity (hand) and lower extremity (foot) images will be used to record reaction time (motor imagery reaction time) and accuracy rate. All tests will be performed under standardized conditions, in a seated position, and using the same device.
- Conditions
- Spinal Cord Injuries
- Being tested
- No intervention
- Medical subject headings
- Spinal Cord Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No interventionOther
No intervention
| Study group | Role | What they receive |
|---|---|---|
| SCI group | Patients with spinal cord injury Receives: Other: No intervention | |
| Control group | Healthy controls Receives: Other: No intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Motor Imagery Reaction Time - Upper Extremity
Reaction time (in milliseconds) required to correctly identify left or right hand images in a computer-based motor imagery task. Longer reaction times indicate impaired motor imagery processing.
Measured: Baseline
Motor Imagery Reaction Time - Lower Extremity
Reaction time (in milliseconds) required to correctly identify left or right foot images. Higher values indicate slower motor imagery performance.
Measured: Baseline
Secondary outcomes (3)
Functional Independence
Functional independence will be assessed only in individuals with spinal cord injury. Scores range from 0 to 100, with higher scores indicating greater independence.
Measured: Baseline
Hospital Anxiety and Depression Scale - Anxiety Subscale (HADS-A)
Scores range from 0 to 21, with higher scores indicating greater anxiety.
Measured: Baseline
Hospital Anxiety and Depression Scale - Depression Subscale (HADS-D)
Scores range from 0 to 21, with higher scores indicating greater depressive symptoms.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Apr 2026
- Study start20 Apr 2026 (estimated)
- Primary completion20 May 2026 (estimated)
- Study completion20 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Spinal Cord InjuriesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 128 participants (estimated)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07549087
- Sponsor's protocol ID
- istftreah12
- Status last verified
- Apr 2026
- First submitted
- 18 Apr 2026
- Last updated
- 23 Apr 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Upper and Lower Extremity Motor Imagery Reaction Time in Individuals With Paraplegic Spinal Cord Injury: A Comparative Study With Healthy Controls
- ClinicalTrials.gov ID
- NCT07549087
- Acronym / sponsor ID
- istftreah12
- Conditions
- Spinal Cord Injuries
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 128 participants (estimated)
- Lead sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research HospitalOther government
- Study start
- 20 Apr 2026 (estimated)
- Primary completion
- 20 May 2026 (estimated)
- Study completion
- 20 May 2026 (estimated)
- First posted
- 23 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Individuals aged 18-65 years who have been clinically diagnosed with spinal cord injury and have developed paraplegia will be included in the study. Demographic and clinical data of the participants, including age, sex, height, weight, etiology of injury, level of injury, duration of injury, and comorbidities, will be recorded. In addition, disease-specific characteristics such as ambulation status, wheelchair use, presence of incontinence, and presence and severity of pain will be assessed. For the healthy control group, demographic data including age, sex, height, weight, and comorbidities will be recorded.
Motor imagery performance of the participants will be evaluated using a computer-based left/right judgment task. In this context, both upper extremity (hand) and lower extremity (foot) images will be used to record reaction time (motor imagery reaction time) and accuracy rate. All tests will be performed under standardized conditions, in a seated position, and using the same device.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Day
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| SCI group | – | Other: No interventionPatients with spinal cord injury |
| Control group | – | Other: No interventionHealthy controls |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Age groups
- Adult, Older adult
- Study population
- The study population will consist of individuals aged 18-65 years with a clinical diagnosis of spinal cord injury and paraplegia who are followed in the inpatient and outpatient clinics of Istanbul Physical Therapy and Rehabilitation Training and Research Hospital. A healthy control group, matched for age and sex, will also be included. Participants will be recruited from patients presenting to the clinic during the study period and from healthy volunteers. All participants will be medically stable and able to complete the study assessments.
Key inclusion criteria (9 listed)
- Aged between 18 and 65 years
- Clinically diagnosed with spinal cord injury
- Presence of paraplegia
- Injury duration of at least 3 months
- Medically stable condition
Key exclusion criteria (8 listed)
- Tetraplegia
- History of other neurological disorders that may affect motor imagery performance
- Severe cognitive impairment or communication problems preventing proper participation
- Severe visual impairment uncorrected by glasses or lenses
- Upper or lower extremity musculoskeletal disorders, deformities, or recent injuries that may affect task performance
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No interventionNo intervention | Other | Control group, SCI group |
Primary outcome
Motor Imagery Reaction Time - Upper Extremity
Time frame: Baseline
Reaction time (in milliseconds) required to correctly identify left or right hand images in a computer-based motor imagery task. Longer reaction times indicate impaired motor imagery processing.
Motor Imagery Reaction Time - Lower Extremity
Time frame: Baseline
Reaction time (in milliseconds) required to correctly identify left or right foot images. Higher values indicate slower motor imagery performance.
3 secondary outcomes
Functional Independence
Time frame: Baseline
Hospital Anxiety and Depression Scale - Anxiety Subscale (HADS-A)
Time frame: Baseline
Hospital Anxiety and Depression Scale - Depression Subscale (HADS-D)
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Apr 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Spinal Cord Injuries, run by Istanbul Physical Medicine Rehabilitation Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 23 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Motor Imagery Reaction Time - Upper Extremity (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Apr 2026.